Neurosciences
Scientists probe origins of brain disorders
By University of Edinburgh
Apr 25, 2005, 22:40

Many currently incurable diseases of the nervous system are likely to have their origin in problems which happen during the growth of the brain �but pinpointing where the defects occur is like finding a needle in a haystack, says a University of Edinburgh scientist. However, in his inaugural lecture on Tuesday, 19 April, Professor David Price will explain that research during the past twenty years has given hope for better understanding of the origins of diseases like epilepsy, motor neurone disease and schizophrenia.

He says: �The human brain is staggeringly complex: 15 billion cells with about a thousand billion connections between them. Understanding how the development of such a complex structure is controlled might seem an impossible task, but research in the past twenty years has made us more optimistic."

�In the mid-1980s, research that built on the earlier discovery, in the 1950s, of the structure of DNA and the genetic code, revolutionised our understanding of how simple organisms, such as insects, develop. And then a truly remarkable discovery was made� that the genes and genetic mechanisms which control development of even very simple organisms are retained in humans. This gives us hope that research on organisms with rudimentary brains will help us learn a lot about how our own brains develop.�

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