XML Feed for RxPG News   Add RxPG News Headlines to My Yahoo!   Javascript Syndication for RxPG News

Research Health World General
 
  Home
 
 Latest Research
 Cancer
 Psychiatry
 Genetics
 Surgery
  CTVS
  Transplantation
 Aging
 Ophthalmology
 Gynaecology
 Neurosciences
 Pharmacology
 Cardiology
 Obstetrics
 Infectious Diseases
 Respiratory Medicine
 Pathology
 Endocrinology
 Immunology
 Nephrology
 Gastroenterology
 Biotechnology
 Radiology
 Dermatology
 Microbiology
 Haematology
 Dental
 ENT
 Environment
 Embryology
 Orthopedics
 Metabolism
 Anaethesia
 Paediatrics
 Public Health
 Urology
 Musculoskeletal
 Clinical Trials
 Physiology
 Biochemistry
 Cytology
 Traumatology
 Rheumatology
 
 Medical News
 Health
 Opinion
 Healthcare
 Professionals
 Launch
 Awards & Prizes
 
 Careers
 Medical
 Nursing
 Dental
 
 Special Topics
 Euthanasia
 Ethics
 Evolution
 Odd Medical News
 Feature
 
 World News
 Tsunami
 Epidemics
 Climate
 Business
Search

Last Updated: Aug 19th, 2006 - 22:18:38

Surgery Channel
subscribe to Surgery newsletter

Latest Research : Surgery

   DISCUSS   |   EMAIL   |   PRINT
Supplemental Oxygen During Surgery Reduces Risk of Wound Infection
Oct 26, 2005, 22:59, Reviewed by: Dr.

"This result is consistent with most available in vitro data and 1 other appropriately designed randomized controlled trial. Supplemental oxygen appears to confer few risks to the patient, has little associated cost, and should be considered part of ongoing quality improvement activities related to surgical care."

 
Patients who received a higher concentration of supplemental oxygen during colorectal surgery had a significantly reduced risk of wound infection, according to a study in the October 26 issue of JAMA.

Surgical wound infections prolong hospitalization by an average of 1 week and substantially increase the cost of care, according to background information in the article. These infections are possibly the most common serious complication of surgery and anesthesia. Supplemental oxygen during and after surgery has been variously reported to halve or double the risk of surgical wound infection.

F. Javier Belda, M.D., Ph.D., of the Hospital Cl�nico Universitario de Valencia, Spain, and colleagues conducted a study to determine whether supplemental perioperative (performed at or around the time of an operation) oxygen reduces the risk of wound infection. The double-blind, randomized controlled trial included 300 patients aged 18 to 80 years who underwent elective colorectal surgery in 14 Spanish hospitals from March 1, 2003, to October 31, 2004. Baseline patient characteristics, anesthetic treatment, and potential confounding factors were recorded. Patients were randomly assigned to an oxygen/air mixture with a fraction (concentration) of inspired oxygen (Fio2) of 30 percent or 80 percent intraoperatively and for 6 hours after surgery.

A total of 143 patients received 30 percent perioperative oxygen and 148 received 80 percent perioperative oxygen. Surgical site infection (SSI) occurred in 35 patients (24.4 percent) administered 30 percent Fio2, and in 22 patients (14.9 percent) administered 80 percent Fio2.

" � we found that 80 percent supplemental oxygen reduced the risk of SSI by 39 percent. When controlling for multiple contributing factors, the reduction in SSI risk associated with 80 percent Fio2 was nearly 54 percent. Patients with infections had significantly longer hospital stays and delays to ambulation," the researchers write.

"This result is consistent with most available in vitro data and 1 other appropriately designed randomized controlled trial. Supplemental oxygen appears to confer few risks to the patient, has little associated cost, and should be considered part of ongoing quality improvement activities related to surgical care," the authors conclude.

In an accompanying editorial, E. Patchen Dellinger, M.D., of the University of Washington School of Medicine, Seattle, comments on the topic of preventing wound infection.

"� a large number of other factors and interventions are known to influence risk for SSI in operative patients. For many of these interventions, there is essentially no controversy, and yet they are not being consistently delivered to patients. Recent surveys of actual practice in the United States show that proper choice of prophylactic antibiotic, timing of antibiotic delivery, avoidance of shaving the surgical site, keeping the patient warm in the operating department, and maintaining normoglycemia are not achieved in 10 percent to 55 percent of patients. Recent quality improvement SSI surveillance data from 1 hospital has demonstrated that when an SSI does occur, in more than 70 percent of the cases, known preventive measures, such as antibiotic delivery and maintenance of normothermia [normal body temperature], were not achieved. A focused effort to change these conditions can result in a dramatic reduction in SSI."

"Surgeons and members of surgical teams should all be working in these areas until more definitive information about oxygen concentrations in the operating department becomes available. Surgeons should encourage the broader use of higher oxygen tensions for their patients undergoing major abdominal procedures and be more involved in quality improvement initiatives aimed at reducing SSI," Dr. Dellinger concludes.
 

- October 26 issue of JAMA
 

Read Research Article at JAMA Journal Website

 
Subscribe to Surgery Newsletter
E-mail Address:

 



Related Surgery News

Predicting survival in liver transplant patients
Many urinary stones can be treated without surgery
Mathematical tools for predicting facial surgery results
SALT protocol improves quality of donor lungs significantly
Costimulation blockade: Will this lead to rejection-free transplants?
Bringing space age to surgery equipment, procedures
Hepatorenal syndrome patients best benefited by a combined liver-kidney transplant
Botox Injections Help Minimize Facial Scars
Microskin relieves emotional trauma for child burn victims
'Domino' transplant program makes best use of altruistic donated kidneys


For any corrections of factual information, to contact the editors or to send any medical news or health news press releases, use feedback form

Top of Page

 

© Copyright 2004 onwards by RxPG Medical Solutions Private Limited
Contact Us