http://www.rxpgnews.com/ Medical News and Information Thu, 21 Aug 2008 02:00:28 PST en-us http://www.rxpgnews.com/creutzfeldtjakobdisease/Seven_UK_cases_of_Creutzfeldt-Jakob_disease_associ_4099_4099.shtml CJD Seven cases of Creutzfeldt-Jakob disease (CJD) associated with transplanted human tissue have occurred in the UK over a period of 33 years, reveals a study published ahead of print in the Journal of Neurology Neurosurgery and Psychiatry. Thu, 20 Apr 2006 16:50:00 PST http://www.rxpgnews.com/creutzfeldtjakobdisease/Seven_UK_cases_of_Creutzfeldt-Jakob_disease_associ_4099_4099.shtml http://www.rxpgnews.com/creutzfeldtjakobdisease/First_Successful_Blood_Test_for_Mad_Cow_Disease_Pr_2177_2177.shtml CJD Researchers at the University of Texas Medical Branch at Galveston (UTMB) have found a way to detect in blood the malformed proteins that cause "mad cow disease," the first time such "prions" have been detected biochemically in blood. Mon, 29 Aug 2005 23:22:00 PST http://www.rxpgnews.com/creutzfeldtjakobdisease/First_Successful_Blood_Test_for_Mad_Cow_Disease_Pr_2177_2177.shtml http://www.rxpgnews.com/creutzfeldtjakobdisease/Blocking_apoptosis_fails_to_stop_prion_damage_in_m_180_180.shtml CJD Researchers knew that prions, the misfolded proteins that cause mad cow disease and other brain disorders, were killing off a class of important brain cells in a transgenic mouse model. But when they found a way to rescue those cells, they were astonished to discover the mice still became sick. Thu, 23 Dec 2004 13:07:00 PST http://www.rxpgnews.com/creutzfeldtjakobdisease/Blocking_apoptosis_fails_to_stop_prion_damage_in_m_180_180.shtml http://www.rxpgnews.com/creutzfeldtjakobdisease/Mad_cow_prions_piggyback_on_iron-storing_proteins__162_162.shtml CJD A new study from the Department of Pathology at Case Western Reserve University School of Medicine shows that the infectious version of prion proteins, the main culprits behind the human form of mad cow disease or variant Creutzfeldt-Jakob Disease (vCJD), are not destroyed by digestive enzymes found in the stomach. Furthermore, the study finds that the infectious prion proteins, also known as prions, cross the normally stringent intestinal barrier by riding piggyback on ferritin, a protein normally absorbed by the intestine and abundantly present in a typical meat dish. The study appears in the Dec. 15 issue of the Journal of Neuroscience. Thu, 16 Dec 2004 18:50:00 PST http://www.rxpgnews.com/creutzfeldtjakobdisease/Mad_cow_prions_piggyback_on_iron-storing_proteins__162_162.shtml http://www.rxpgnews.com/creutzfeldtjakobdisease/Testing_Transepithelial_Prion_Protein_Transport_In_161_161.shtml CJD The discovery of the "mad cow" variant of Creutzfeldt–Jakob disease (CJD) as a foodborne illness not only created a worldwide scare but also focused attention on the mechanisms of transmission of the infective agent, the scrapie prion protein (PrPSc). Wed, 15 Dec 2004 18:45:00 PST http://www.rxpgnews.com/creutzfeldtjakobdisease/Testing_Transepithelial_Prion_Protein_Transport_In_161_161.shtml