http://www.rxpgnews.com/ Medical News and Information Thu, 25 Oct 2007 07:48:36 PST en-us http://www.rxpgnews.com/cysticfibrosis/Cystic_fibrosis-related_diabetes_is_due_to_functio_4659_4659.shtml Cystic Fibrosis A growing number of cystic fibrosis patients are battling a second, often deadly complication: a unique form of diabetes that shares characteristics of the type 1 and type 2 versions that strike many Americans. Many of these patients are teens who take enzymes to help digest their food and undergo daily physical therapy to loosen the thick, sticky mucus that clogs their lungs. But despite treatments that are helping thousands to live decades longer than ever before, when diabetes strikes, their life expectancy plummets -- on average by two years for men and an astounding 16 for women. Mon, 10 Jul 2006 06:21:00 PST http://www.rxpgnews.com/cysticfibrosis/Cystic_fibrosis-related_diabetes_is_due_to_functio_4659_4659.shtml http://www.rxpgnews.com/cysticfibrosis/No_evidence_for_inhaled_corticosteroids_efficacy_i_4465_4465.shtml Cystic Fibrosis In comparison to cystic fibrosis (CF) patients who regularly use inhaled corticosteroid, those who did not use these drugs for six months exhibited no positive or negative effects in terms of major disease factors. Such factors include amount of lung function decline, number of antibiotics prescribed, time to onset of acute chest exacerbation or frequency of using a bronchodilator. Thu, 15 Jun 2006 16:57:00 PST http://www.rxpgnews.com/cysticfibrosis/No_evidence_for_inhaled_corticosteroids_efficacy_i_4465_4465.shtml http://www.rxpgnews.com/cysticfibrosis/Hcp1_plays_a_critical_role_in_cystic_fibrosis_infe_4434_4434.shtml Cystic Fibrosis Harvard Medical School researchers have discovered one way that a hardy disease-causing bacteria could be surviving in the lungs of chronically infected cystic fibrosis (CF) patients. This work is important because pathogenic bacteria such as Pseudomonas aeruginosa (PA) use protein secretion systems to cause disease in their hosts. In the case of Pseudomonas aeruginosa, the host may be a cancer patient with a weakened immune system, a burn patient, or a person with cystic fibrosis (CF). Pseudomonas aeruginosa (PA), a pathogen that infects more than 80 percent of cystic fibrosis patients, is a leading cause of these patients' death. PA is difficult to treat because it is resistant to many drugs. Sat, 10 Jun 2006 13:43:00 PST http://www.rxpgnews.com/cysticfibrosis/Hcp1_plays_a_critical_role_in_cystic_fibrosis_infe_4434_4434.shtml http://www.rxpgnews.com/cysticfibrosis/Cystic_fibrosis_research_could_benefit_from_multi-_3796_3796.shtml Cystic Fibrosis Researchers are using an innovative, multi-functional sensing tool to investigate adenosine triposphate (ATP) release and its role in cystic fibrosis. The ATP study marks the first application of a novel sensing system developed by a research team led by Christine Kranz at the Georgia Institute of Technology. Mon, 27 Mar 2006 16:17:00 PST http://www.rxpgnews.com/cysticfibrosis/Cystic_fibrosis_research_could_benefit_from_multi-_3796_3796.shtml http://www.rxpgnews.com/cysticfibrosis/Loss_of_CFTR-mediated_fluid_secretion_is_the_culpr_3703_3703.shtml Cystic Fibrosis Scientists at Stanford University have determined that the buildup of sticky mucus found in cystic fibrosis is caused by a loss in the epithelial cell's ability to secrete fluid. This research appears as the "Paper of the Week" in the March 17 issue of the Journal of Biological Chemistry, an American Society for Biochemistry and Molecular Biology journal. Sun, 19 Mar 2006 20:56:00 PST http://www.rxpgnews.com/cysticfibrosis/Loss_of_CFTR-mediated_fluid_secretion_is_the_culpr_3703_3703.shtml http://www.rxpgnews.com/cysticfibrosis/New_treatment_for_cystic_fibrosis_patients_3145_3145.shtml Cystic Fibrosis Scientists have discovered a new therapy for lung problems associated with cystic fibrosis that they say may reduce the use of antibiotics. Thu, 19 Jan 2006 13:10:00 PST http://www.rxpgnews.com/cysticfibrosis/New_treatment_for_cystic_fibrosis_patients_3145_3145.shtml http://www.rxpgnews.com/cysticfibrosis/Genetic_variations_influence_cystic_fibrosis_sever_2600_2600.shtml Cystic Fibrosis Subtle differences in other genes -- besides the defective gene known to cause the illness cystic fibrosis -- can significantly modify the inherited disease's severity, a large new multi-center national study has concluded. The study, led by University of North Carolina at Chapel Hill and Case Western Reserve University researchers, for the first time shows that particular versions of the transforming growth factor beta 1 (TGFb1) gene are largely responsible for how badly the illness affects patients' lungs. Sat, 08 Oct 2005 05:24:00 PST http://www.rxpgnews.com/cysticfibrosis/Genetic_variations_influence_cystic_fibrosis_sever_2600_2600.shtml http://www.rxpgnews.com/cysticfibrosis/How_to_design_a_better_drug_to_treat_cystic_fibros_2224_2224.shtml Cystic Fibrosis There is no cure for cystic fibrosis. Management of the disease varies from person to person and generally focuses on treating respiratory and digestive problems to prevent infection and other complications. Treatment usually involves a combination of medications and home treatment methods, such as respiratory and nutritional therapies. Sun, 04 Sep 2005 08:30:00 PST http://www.rxpgnews.com/cysticfibrosis/How_to_design_a_better_drug_to_treat_cystic_fibros_2224_2224.shtml http://www.rxpgnews.com/cysticfibrosis/FDA_Gives_Clearance_to_the_First_Cystic_Fibrosis_D_1427_1427.shtml Cystic Fibrosis Tm Bioscience Corporation (Toronto, Ontario; TSX: TMC), a leader in the commercial genetic testing market, is pleased to announce that its Tag-It(TM) Cystic Fibrosis (CF) Kit is the first multiplexed human disease genotyping test to be cleared by the U.S. Food and Drug Administration (FDA) as an in vitro device (IVD) for diagnostic use in the United States. Tue, 10 May 2005 09:18:00 PST http://www.rxpgnews.com/cysticfibrosis/FDA_Gives_Clearance_to_the_First_Cystic_Fibrosis_D_1427_1427.shtml