RxPG News : Metabolic Syndrome

Single mechanism to explain metabolic syndrome

Mon, 30 Jun 2008 09:00:11 PST

Many of the 75 million Americans with essential hypertension also develop diabetes and other complications in addition to their high blood pressure, and researchers have discovered a common molecular mechanism in a strain of rat that explains why such metabolic disorders arise together in mammals.

Weight loss better than insulin therapy in type 2 Diabetes Mellitus

Tue, 11 Mar 2008 15:28:05 PST

Weight-loss and major lifestyle changes may be more effective than intensive insulin therapy for overweight patients with poorly controlled, insulin-resistant type 2 diabetes, according to a diabetes researcher at UT Southwestern Medical Center.

Separate mechanisms in metabolic syndrome- Akt and atypical PKC

Sun, 14 May 2006 18:55:00 PST

The new study, led by C. Ronald Kahn, M.D., and Cullen Taniguchi, M.D., Ph.D., of Joslin Diabetes Center in Boston and their colleagues, is published in the May edition of Cell Metabolism. The findings open the door to the development of new treatments that one day may target directly the conditions that contribute to type 2 diabetes and the metabolic syndrome.

New clinical team approach reduced cardiovascular risk for obese metabolic syndrome patients

Mon, 01 May 2006 00:47:00 PST

Obesity researchers at the Medical College of Wisconsin in Milwaukee found that a multidisciplinary clinical approach to caring for obese patients with metabolic syndrome could swiftly and significantly lower their risk for heart disease.

Study warns of growing Metabolic syndrome epidemic in China

Sat, 15 Apr 2006 09:58:00 PST

As more people in China adopt Western diets and lifestyles, many are developing a cluster of cardiovascular disease risk factors, according to a new study in the April 18, 2006, issue of the Journal of the American College of Cardiology.
"The metabolic syndrome has become increasingly common in this Asian population and the prevalence is about to catch up with that in Western populations. That's a very dangerous sign in terms of cardiovascular disease"

Whole grains in diet reduce risk of metabolic syndrome

Tue, 07 Feb 2006 15:27:00 PST

With the recent revision of the Food Guide Pyramid, the Dietary Guidelines for Americans have for the first time provided the public with a quantitative recommendation for whole-grain intake. In a study published in the January issue of American Journal of Clinical Nutrition, researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University (HNRCA) found that consuming a diet rich in whole-grain foods may lower an elderly person's risk for cardiovascular disease and reduce the onset of metabolic syndrome. Metabolic syndrome, which is a collection of risk factors, puts people at an increased risk of cardiovascular disease and type 2 diabetes.

Chronic stress at work and metabolic syndrome

Fri, 20 Jan 2006 15:19:00 PST

Stress at work is an important risk factor for the development of heart disease and diabetes, finds a study published online by the BMJ today.

Low-carb diet better at improving metabolic syndrome

Wed, 16 Nov 2005 19:25:00 PST

Diabetes and cardiovascular disease associated with it. In an article published today in the open access journal Nutrition & Metabolism, Jeff Volek and Richard Feinman review the literature and show that the features of metabolic syndrome are precisely those that are improved by reducing carbohydrates in the diet. Metabolic syndrome is a cluster of health signs that may occur together and indicate a risk for diabetes, stroke and heart disease. The markers of metabolic syndrome - high blood pressure, low HDL levels, high triglycerides, obesity, high blood glucose and high insulin levels are all improved by a low carbohydrate diet. By contrast, the evidence shows that they are not improved, and can even be worsened by low fat/high carbohydrate diets.

Genetics affect the severity of metabolic syndrome

Tue, 25 Oct 2005 22:01:00 PST

Hereditary factors appear to make obese individuals more susceptible to metabolic syndrome, a disorder associated with excess fat around the abdomen that increases the chances of heart disease, stroke and diabetes.

Potential metabolic effects of telmisartan in preliminary studies

Thu, 08 Sep 2005 01:34:00 PST

Preclinical studies show that the angiotensin II receptor blocker (ARB), Micardis® (telmisartan), has a beneficial effect on metabolic parameters including plasma glucose, insulin resistance and lipid abnormalities, in addition to its proven effect on high blood pressure, due to its partial activation of PPAR-gamma (peroxisome proliferator-activated receptor-gamma). PPAR-gamma is a hormone receptor known to have an important role in regulating carbohydrate and lipid metabolism, by increasing insulin sensitivity. High blood pressure, lipid abnormalities, insulin resistance and obesity are key components of metabolic syndrome, a common precursor of cardiovascular disease and type 2 diabetes.

Possible drug targets for treating metabolic syndrome outlined

Thu, 11 Aug 2005 17:29:00 PST

Ongoing studies by researchers at UT Southwestern Medical Center and other institutions have uncovered the biochemical basis of many of the factors contributing to what is known as the metabolic syndrome, suggesting potential new drug targets for treating the condition.

Metabolic syndrome increase risk of blocked arteries

Thu, 26 May 2005 18:47:00 PST

Conditions such as abdominal obesity, high blood pressure, abnormal cholesterol levels and high blood sugar are problematic enough for people all on their own. But when patients have three of these disorders at the same time, they have what is called the "metabolic syndrome" an increasingly prevalent disorder affecting up to 40 percent of the adult population in the United States frequently leading to diabetes and accelerated heart disease.

Metabolic syndrome - bad prognosis in MI

Thu, 26 May 2005 03:00:00 PST

Metabolic syndrome was known to be associated with cardiovascular risk factors. But this study shows metabolic syndrome to be associated with worse in-hospital outcomes, and an increased risk of heart failure in patients admitted with an acute myocardial infarction.

Effect of Plant Extracts on Metabolic Syndrome to be Investigated

Wed, 04 May 2005 18:17:00 PST

Rutgers University plant scientists are truly into something hot. They are working with a research laboratory named for the late Tabasco® Pepper Sauce heir, John S. McIlhenny, and built with a gift from the trust he established, the Coypu Foundation. The lab is part of the Pennington Biomedical Research Center, a campus of the Louisiana State University system. At this facility, researchers collaborating with Rutgers colleagues will investigate whether plant extracts can cut risk factors for heart disease, stroke, diabetes or other serious illnesses.

Simple Actions Wipe Out Huge Higher Heart Risks For Asian Diabetics

Mon, 25 Apr 2005 19:41:00 PST

New research, to be revealed on Tuesday 26th of April at the launch of the University of Warwick Medical School's new Clinical Sciences Research Institute at the University Hospital campus at Walsgrave in Coventry, has shown that very simple interventions to target the health care of UK Asian diabetics can almost wipe out the 40% higher risks of heart disease linked to diabetes in that community.