http://www.rxpgnews.com/ Medical News and Information Thu, 25 Oct 2007 07:48:36 PST en-us http://www.rxpgnews.com/research/Massive-microRNA-scan-uncovers-leads-to-treating-muscle-degeneration_69803.shtml Latest Research Researchers have discovered the first microRNAs – tiny bits of code that regulate gene activity – linked to each of 10 major degenerative muscular disorders, opening doors to new treatments and a better biological understanding of these debilitating, poorly understood, often untreatable diseases. The study, to be published online this week by the Proceedings of the National Academy of Sciences, was led by Iris Eisenberg, PhD, of the Program in Genomics at Children’s Hospital Boston. Louis Kunkel, PhD, director of the Program in Genomics and an investigator with the Howard Hughes Medical Institute, was senior investigator. Wed, 17 Oct 2007 04:00:00 PST http://www.rxpgnews.com/research/Massive-microRNA-scan-uncovers-leads-to-treating-muscle-degeneration_69803.shtml http://www.rxpgnews.com/research/FDA-approves-knee-injury-device-for-humans_66888.shtml Latest Research COLUMBIA, Mo. – A new knee-surgery device investigated by University of Missouri-Columbia researchers that will help to repair meniscus tears, which were previously defined as irreparable, has been approved by the FDA for use in humans. Tue, 02 Oct 2007 04:00:00 PST http://www.rxpgnews.com/research/FDA-approves-knee-injury-device-for-humans_66888.shtml http://www.rxpgnews.com/neurosciences/Brain-abnormalities-found-in-people-with-writers-cramp_53658.shtml Neurosciences People with serious cases of writer�s cramp have brain abnormalities, according to a study published in the July 24, 2007, issue of Neurology, the medical journal of the American Academy of Neurology. People with writer�s cramp had less brain tissue than healthy people in three areas of the brain that connect the senses and movement with their affected hand. Mon, 23 Jul 2007 04:00:00 PST http://www.rxpgnews.com/neurosciences/Brain-abnormalities-found-in-people-with-writers-cramp_53658.shtml http://www.rxpgnews.com/research/Sports-hernia-repair-technique-coupled-with-innovative-rehabilitation-program-speeds-return-to-play_52065.shtml Latest Research CALGARY, Alberta -- Surgical repair of athletic hernia using tension-free mesh and a standardized rehabilitation protocol are successful in returning athletes to competition, according to new research released today at the 2007 Annual Meeting of the American Orthopaedic Society for Sports Medicine at the Telus Convention Center (July 12-15). Sun, 15 Jul 2007 04:00:00 PST http://www.rxpgnews.com/research/Sports-hernia-repair-technique-coupled-with-innovative-rehabilitation-program-speeds-return-to-play_52065.shtml http://www.rxpgnews.com/research/Sports-hernia-repair-surgery-plus-innovative-rehab-program-helps-athletes-return-to-play_52067.shtml Latest Research St. Louis, July 15, 2007 — In recent years, sports hernias have sidelined many high-level athletes for months and, occasionally, prevented a return to competitive sports all together. New research at Washington University School of Medicine in St. Louis shows that surgical repair of sports hernias using tension-free mesh, coupled with an innovative rehabilitation program, successfully returned athletes to competition in 93 percent of cases. Sun, 15 Jul 2007 04:00:00 PST http://www.rxpgnews.com/research/Sports-hernia-repair-surgery-plus-innovative-rehab-program-helps-athletes-return-to-play_52067.shtml http://www.rxpgnews.com/research/Tennis-elbow-procedure-demonstrates-long-term-success_51954.shtml Latest Research CALGARY, Alberta -- Arthroscopic treatment of tennis elbow has shown to be successful at long-term follow-up, according to new research released today at the 2007 Annual Meeting of the American Orthopaedic Society for Sports Medicine at the Telus Convention Center (July 12-15). Sat, 14 Jul 2007 04:00:00 PST http://www.rxpgnews.com/research/Tennis-elbow-procedure-demonstrates-long-term-success_51954.shtml http://www.rxpgnews.com/research/Women-and-arthritis-sufferers-have-poorer-short-term-recovery-from-arthroscopic-knee-surgery_51955.shtml Latest Research CALGARY, Alberta -- The factors associated with poor short-term recovery from knee surgery appear to be different than those found to mar long-term outcome from the same surgery, according to new research released today at the 2007 Annual Meeting of the American Orthopaedic Society for Sports Medicine at the Telus Convention Center (July 12-15). Sat, 14 Jul 2007 04:00:00 PST http://www.rxpgnews.com/research/Women-and-arthritis-sufferers-have-poorer-short-term-recovery-from-arthroscopic-knee-surgery_51955.shtml http://www.rxpgnews.com/research/Serica-scientists-win-AOSSM-Award-for-ACL--tissue-regeneration-in-preclinical-study_51908.shtml Latest Research MEDFORD, MA and CALGARY, CANADA, JULY13, 2007 -- Serica Technologies, Inc., a growth-stage medical device company developing silk-based biomaterial platforms for tissue regeneration, today announced that its scientists received the Cabaud Memorial Award from the American Orthopedic Society for Sports Medicine (AOSSM), for their pre-clinical research demonstrating the potential of SericaÂ’s SeriACL™ Graft to regenerate or re-grow anterior cruciate ligament (ACL) tissue in the knee, in a large-animal model. Fri, 13 Jul 2007 04:00:00 PST http://www.rxpgnews.com/research/Serica-scientists-win-AOSSM-Award-for-ACL--tissue-regeneration-in-preclinical-study_51908.shtml http://www.rxpgnews.com/research/Groin-injuries-averted-by-preseason-injury-prevention_51561.shtml Latest Research CALGARY, Alberta -- Professional soccer players who participated in a special preseason groin injury prevention program had fewer groin injuries during that subsequent season than those who were not in the program, according to new research released today at the 2007 Annual Meeting of the American Orthopaedic Society for Sports Medicine at the Telus Convention Center (July 12-15). Thu, 12 Jul 2007 04:00:00 PST http://www.rxpgnews.com/research/Groin-injuries-averted-by-preseason-injury-prevention_51561.shtml http://www.rxpgnews.com/research/Neoprene-sleeve-equal-to-knee-brace-during-recovery-from-ACL-surgery_51562.shtml Latest Research CALGARY, Alberta -- Users of functional knee braces and neoprene sleeves have similar recoveries from anterior cruciate ligament (ACL) reconstruction, according to new research presented today at the 2007 Annual Meeting of the American Orthopaedic Society for Sports Medicine at the Telus Convention Center (July 12-15). Thu, 12 Jul 2007 04:00:00 PST http://www.rxpgnews.com/research/Neoprene-sleeve-equal-to-knee-brace-during-recovery-from-ACL-surgery_51562.shtml http://www.rxpgnews.com/research/Penn-researchers-find-a-new-target-for-muscular-dystrophy-drug-therapy_51746.shtml Latest Research PHILADELPHIA - Researchers at the University of Pennsylvania School of Medicine report how the gene for utrophin, which codes for a protein very similar to dystrophin, the defective protein in Duchenne muscular dystrophy (DMD), puts the brakes on its own expression in muscle cells, thereby suggesting a new target for treatment. The findings were published online in Molecular Biology Cell, in advance of print publication. Thu, 12 Jul 2007 04:00:00 PST http://www.rxpgnews.com/research/Penn-researchers-find-a-new-target-for-muscular-dystrophy-drug-therapy_51746.shtml http://www.rxpgnews.com/research/Anti-malarial-drug-may-reduce-risk-of-diabetes-for-patients-with-rheumatoid-arthritis_51302.shtml Latest Research Preliminary research suggests that use of the anti-malarial drug hydroxychloroquine may help reduce the risk of the development of diabetes in patients with rheumatoid arthritis, according to a study in the July 11 issue of JAMA. Tue, 10 Jul 2007 04:00:00 PST http://www.rxpgnews.com/research/Anti-malarial-drug-may-reduce-risk-of-diabetes-for-patients-with-rheumatoid-arthritis_51302.shtml http://www.rxpgnews.com/research/More-muscle-for-the-argument-to-give-up-smoking_51044.shtml Latest Research Researchers at The University of Nottingham have got more bad news for smokers. Not only does it cause cancer, heart attacks and strokes but smokers will also lose more muscle mass in old age than a non-smoker. The effect of this predisposes smokers to an accelerated decline in physical function and loss of independence. Mon, 09 Jul 2007 04:00:00 PST http://www.rxpgnews.com/research/More-muscle-for-the-argument-to-give-up-smoking_51044.shtml http://www.rxpgnews.com/research/Faulty-cell-membrane-repair-causes-heart-disease_48421.shtml Latest Research During vigorous exercise, heart muscle cells take a beating. In fact, some of those cells rupture, and if not for a repair process capable of resealing cell membranes, those cells would die and cause heart damage (cardiomyopathy). Tue, 03 Jul 2007 04:00:00 PST http://www.rxpgnews.com/research/Faulty-cell-membrane-repair-causes-heart-disease_48421.shtml http://www.rxpgnews.com/research/New-dynamic-brace-developed-to-advance-clubfoot-treatment_48012.shtml Latest Research A new brace that maintains correction for clubfoot, a birth defect in which the foot is turned in toward the body, has shown better compliance and fewer complications than the traditional brace used to treat the condition. Thu, 28 Jun 2007 04:00:00 PST http://www.rxpgnews.com/research/New-dynamic-brace-developed-to-advance-clubfoot-treatment_48012.shtml http://www.rxpgnews.com/research/New-genetic-test-developed-at-Emory-advances-detection-and-diagnosis-of-muscular-dystrophy_47914.shtml Latest Research A new genetic test targeting the most common types of muscular dystrophy--those caused by mutations in the dystrophin gene--is far quicker with greater accuracy and sensitivity than existing tests. It can be used to confirm clinical diagnoses, to test female family members who may be carriers, and to perform prenatal testing. Wed, 27 Jun 2007 04:00:00 PST http://www.rxpgnews.com/research/New-genetic-test-developed-at-Emory-advances-detection-and-diagnosis-of-muscular-dystrophy_47914.shtml http://www.rxpgnews.com/research/Mouse-model-points-to-possible-new-strategy-for-treating-rare-muscle-disease-kidney-disorders_37683.shtml Latest Research Based on clues provided by a study with transgenic mice, a research group at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), has developed a strategy that will be tested as the first treatment for people with hereditary inclusion body myopathy (HIBM), a rare, degenerative muscle disease. In an unexpected finding, the research indicates that the approach also might benefit patients with certain kidney disorders. Fri, 01 Jun 2007 04:00:00 PST http://www.rxpgnews.com/research/Mouse-model-points-to-possible-new-strategy-for-treating-rare-muscle-disease-kidney-disorders_37683.shtml http://www.rxpgnews.com/research/When-the-villain-becomes-your-friend-The-strange-tale-of-muscle-lactate_41762.shtml Latest Research In a paper published this week in The Journal of Physiology, Frank de Paoli and colleagues, working at the University of Aarhus in Denmark, add to the growing literature leading to a more complete understanding of the physiological role of lactic acid production in muscle. Thu, 31 May 2007 04:00:00 PST http://www.rxpgnews.com/research/When-the-villain-becomes-your-friend-The-strange-tale-of-muscle-lactate_41762.shtml http://www.rxpgnews.com/research/Existence-of-muscle-building-stem-cells-points-to-regenerative-therapies-for-muscular-disease_42307.shtml Latest Research A new report in the June 1 issue of the journal Cell, a publication of Cell Press, confirms the existence of some apparently uncommitted stem cells amongst cells responsible for generating the bulging biceps of body builders and the rippling abs of fitness buffs. The findings could lead to new muscle-regenerating therapies—including cell transplantation regimens and stem cell-replenishing drugs—for people with various muscle-wasting diseases, including muscular dystrophies. Ultimately, such treatments might also help keep people strong as they age, according to the researchers. Thu, 31 May 2007 04:00:00 PST http://www.rxpgnews.com/research/Existence-of-muscle-building-stem-cells-points-to-regenerative-therapies-for-muscular-disease_42307.shtml http://www.rxpgnews.com/research/Research-shows-aerobic-exercise-helps-maintain-muscle-in-elderly_37356.shtml Latest Research GALVESTON, Texas — Why do older people tend to lose muscle mass and grow frail? One important factor identified by medical science is the reduced ability of the elderly to respond to the muscle-building stimulus of the hormone insulin. Wed, 30 May 2007 04:00:00 PST http://www.rxpgnews.com/research/Research-shows-aerobic-exercise-helps-maintain-muscle-in-elderly_37356.shtml http://www.rxpgnews.com/research/Biofeedback-on-abnormal-mechanics-lowers-risk-for-stress-fractures-pain-under-kneecap_32153.shtml Latest Research More than seven out of 10 runners will sustain an injury over the course of a year, many of these injuries preventable without any adverse effects on running distance or performance, according to Dr. Irene Davis, director of the Running Injury Lab at the University of Delaware, and director of Research for Drayer Physical Therapy Institute. Mon, 30 Apr 2007 04:00:00 PST http://www.rxpgnews.com/research/Biofeedback-on-abnormal-mechanics-lowers-risk-for-stress-fractures-pain-under-kneecap_32153.shtml http://www.rxpgnews.com/research/Free-weight-training-gets-workers-with-rotator-cuff-injuries-back-on-the-job_32057.shtml Latest Research Resistance training, some of it job-specific, was successful in getting 90 percent of workers with severe rotator cuff injuries back to work, the majority (75 percent) at their previous job, after traditional physical therapy had failed to do so. Furthermore, all but one of the 42 employees in the study (98 percent) reported satisfaction with the resistance-training program and its outcome. Sun, 29 Apr 2007 04:00:00 PST http://www.rxpgnews.com/research/Free-weight-training-gets-workers-with-rotator-cuff-injuries-back-on-the-job_32057.shtml http://www.rxpgnews.com/research/Green-tea-compound-suppresses-factors-causing-cartilage-bone-destruction-in-arthritis_32208.shtml Latest Research In rheumatoid arthritis, a person's own immune system attacks the joints by activating the synovial tissue that lines the body's movable joints, causing inflammation, swelling, pain and eventually erosion of the bone and cartilage and deformation of the joint. It is among the most debilitating forms of arthritis, often making difficult even the simplest of daily activities. Sun, 29 Apr 2007 04:00:00 PST http://www.rxpgnews.com/research/Green-tea-compound-suppresses-factors-causing-cartilage-bone-destruction-in-arthritis_32208.shtml http://www.rxpgnews.com/research/Measuring-calcium-intake-can-help-to-identify-osteoporosis-in-men-with-prostate-cancer_32546.shtml Latest Research Measuring a manÂ’s daily calcium intake is an effective way of identifying prostate cancer patients with a higher than average risk of osteoporosis, according to the April issue of the urology journal BJU International. Tue, 10 Apr 2007 04:00:00 PST http://www.rxpgnews.com/research/Measuring-calcium-intake-can-help-to-identify-osteoporosis-in-men-with-prostate-cancer_32546.shtml http://www.rxpgnews.com/research/The-sturdier-sex----Study-by-Pittsburgh-scientists-finds-female-stem-cells-work-better_31902.shtml Latest Research PITTSBURGH – April 4, 2007 -- Female stem cells derived from muscle have a greater ability to regenerate skeletal muscle tissue than male cells, according to a study at ChildrenÂ’s Hospital of Pittsburgh of UPMC. Mon, 09 Apr 2007 04:00:00 PST http://www.rxpgnews.com/research/The-sturdier-sex----Study-by-Pittsburgh-scientists-finds-female-stem-cells-work-better_31902.shtml http://www.rxpgnews.com/research/Stevens-and-Connecticut-Innovations-agree-to-investment-of-%24500000-in-SPOC-Inc._32536.shtml Latest Research HOBOKEN, N.J. -- Stevens Institute of Technology and Connecticut Innovations (CI), the stateÂ’s quasi-public authority responsible for technology investing and innovation development, today announced that they had completed an agreement for a seed-stage investment of $500,000 in Stevens Proof of Concept Inc. (SPOC), a Technogenesis® Company founded at Stevens Institute of Technology. CI made this investment through its Connecticut BioSeed Fund. Mon, 02 Apr 2007 04:00:00 PST http://www.rxpgnews.com/research/Stevens-and-Connecticut-Innovations-agree-to-investment-of-%24500000-in-SPOC-Inc._32536.shtml http://www.rxpgnews.com/research/Switching-genes-to-overdrive-improves-muscular-dystrophy-symptoms-in-mice_32017.shtml Latest Research BOSTON -- Scientists at Dana-Farber Cancer Institute have shown in a laboratory study that revving up a crucial set of muscle genes counteracts the damage caused by a form of muscular dystrophy. Sat, 31 Mar 2007 04:00:00 PST http://www.rxpgnews.com/research/Switching-genes-to-overdrive-improves-muscular-dystrophy-symptoms-in-mice_32017.shtml http://www.rxpgnews.com/research/Women-need-expanded-musculoskeletal-care-during-pregnancy-study-finds_31630.shtml Latest Research (Arlington, Va.) -- Despite the high prevalence of musculoskeletal pain during pregnancy, few women in underserved populations receive treatment for their low back pain, according to a February 2007 study in the Journal of Manipulative and Physiological Therapeutics (JMPT). Moreover, researchers found that pain in a previous pregnancy may predict a high risk for musculoskeletal complaints in future pregnancies. Tue, 06 Mar 2007 05:00:00 PST http://www.rxpgnews.com/research/Women-need-expanded-musculoskeletal-care-during-pregnancy-study-finds_31630.shtml http://www.rxpgnews.com/research/Modified-ligament-surgery-improves-outcomes-for-baseball-pitchers-other-athletes_34961.shtml Latest Research In the largest study of its kind, surgeons at Hospital for Special Surgery have determined that by modifying a classic ligament surgery, they can return more athletes, such as baseball players, to their prior level of competition. The modified surgery repairs a torn medial collateral ligament (MCL), which links and stabilizes bones of the lower and upper arm where they meet at the elbow. Wed, 28 Feb 2007 05:00:00 PST http://www.rxpgnews.com/research/Modified-ligament-surgery-improves-outcomes-for-baseball-pitchers-other-athletes_34961.shtml http://www.rxpgnews.com/research/Power-boosting-signal-in-muscle-declines-with-age_34832.shtml Latest Research As people age, they may have to exercise even harder to get the benefits afforded to younger folk. That's the suggestion of a report in the February issue of the journal Cell Metabolism, published by Cell Press, showing that a signal that gives muscles a kind of metabolic boost in response to exercise is blunted in older animals. Tue, 06 Feb 2007 05:00:00 PST http://www.rxpgnews.com/research/Power-boosting-signal-in-muscle-declines-with-age_34832.shtml http://www.rxpgnews.com/research/Common-blood-pressure-drug-reduces-progressive-muscle-degeneration-in-mice_36506.shtml Latest Research Scientists supported in part by the National Institutes of Health's National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and National Institute of Neurological Disorders and Stroke (NINDS) have found that that the commonly prescribed blood pressure medication losartan improves muscle regeneration and repair in a mouse model of Duchenne muscular dystrophy (DMD), a devastating disease characterized by rapid progression of muscle degeneration in boys and young men. The research is based on similarities in the mechanism of DMD and another rare disease — Marfan syndrome — and the discovery that losartan is effective in blocking the key mechanism in animal models of both diseases. Further studies of the drug, scientists emphasize, are needed to assess its value in patients. Fri, 02 Feb 2007 05:00:00 PST http://www.rxpgnews.com/research/Common-blood-pressure-drug-reduces-progressive-muscle-degeneration-in-mice_36506.shtml http://www.rxpgnews.com/research/Smoking-worsens-knee-osteoarthritis_30216.shtml Latest Research ROCHESTER, Minn. -- New findings from a study led by a Mayo Clinic rheumatologist indicate that men with knee osteoarthritis who smoke experience greater cartilage loss and more severe pain than men who do not smoke. Results will be published online this week in the Annals of the Rheumatic Diseases. Thu, 07 Dec 2006 05:00:00 PST http://www.rxpgnews.com/research/Smoking-worsens-knee-osteoarthritis_30216.shtml http://www.rxpgnews.com/research/Improperly-sized-tennis-racket-grip-doesnt-cause-tennis-elbow_30458.shtml Latest Research Rosemont, Ill. – December 1, 2006 – Researchers apparently have gotten a grip on the relationship between the development of tennis elbow (tendonitis) and the size of the grip on the racket a player uses. Fri, 01 Dec 2006 05:00:00 PST http://www.rxpgnews.com/research/Improperly-sized-tennis-racket-grip-doesnt-cause-tennis-elbow_30458.shtml http://www.rxpgnews.com/research/Helping-muscle-regenerate_43171.shtml Latest Research Muscle wasting can occur at all ages as the result of genetic defects, heart failure, spinal injury or cancer. A therapy to cure the loss of muscle mass and strength, which has a severe impact on patients' lives, is desperately sought. Blocking a central signal molecule, researchers from the Mouse Biology Unit of the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy, have now found a way to protect muscle from degenerating after injury and to improve muscle healing in mice. The study appears in the current issue of the Journal of Clinical Investigation and suggests two molecules with the potential to speed up the regeneration of damaged muscle as promising drug targets for new therapies against muscle wasting. Wed, 01 Nov 2006 05:00:00 PST http://www.rxpgnews.com/research/Helping-muscle-regenerate_43171.shtml http://www.rxpgnews.com/musculardystrophies/Trichostatin_A_TSA_Can_Counteract_Muscular_Dystrop_5031_5031.shtml Muscular Dystrophies Scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other institutions have demonstrated for the first time that a single drug can rebuild damaged muscle in two strains of mice that develop diseases comparable to two human forms of muscular dystrophy. This advance, which is reported online in Nature Medicine, is the latest from a research collaboration that began several years ago by the teams of Vittorio Sartorelli, M.D., at NIAMS and Pier Lorenzo Puri, M.D., Ph.D., now at Dulbecco Telethon Institute (DTI) in Rome, Italy and The Burnham Institute in La Jolla, Calif. Thu, 05 Oct 2006 01:08:00 PST http://www.rxpgnews.com/musculardystrophies/Trichostatin_A_TSA_Can_Counteract_Muscular_Dystrop_5031_5031.shtml http://www.rxpgnews.com/research/Scientists-show-drug-can-counteract-muscular-dystrophy-in-mice_45821.shtml Latest Research Scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other institutions have demonstrated for the first time that a single drug can rebuild damaged muscle in two strains of mice that develop diseases comparable to two human forms of muscular dystrophy. This advance, which is reported online in Nature Medicine, is the latest from a research collaboration that began several years ago by the teams of Vittorio Sartorelli, M.D., at NIAMS and Pier Lorenzo Puri, M.D., Ph.D., now at Dulbecco Telethon Institute (DTI) in Rome, Italy and The Burnham Institute in La Jolla, Calif. Wed, 04 Oct 2006 04:00:00 PST http://www.rxpgnews.com/research/Scientists-show-drug-can-counteract-muscular-dystrophy-in-mice_45821.shtml http://www.rxpgnews.com/research/Muscle-cells-self-destruct-rather-than-grow-with-use_45404.shtml Latest Research Muscle cells that should grow stronger with use instead self-destruct when a protein called BAG3 isn't around, researchers have shown. Wed, 30 Aug 2006 04:00:00 PST http://www.rxpgnews.com/research/Muscle-cells-self-destruct-rather-than-grow-with-use_45404.shtml http://www.rxpgnews.com/research/Women-show-47-percent-greater-persistence-with-osteoporosis-drugs-if-offered-monthly-tablet-support_41761.shtml Latest Research Women who took an osteoporosis drug once a month and received extra telephone support from trained nurses showed 47 per cent greater persistence with their drug treatment than those who took a weekly tablet, according to a study in the August issue of IJCP, the International Journal of Clinical Practice. Thu, 20 Jul 2006 04:00:00 PST http://www.rxpgnews.com/research/Women-show-47-percent-greater-persistence-with-osteoporosis-drugs-if-offered-monthly-tablet-support_41761.shtml http://www.rxpgnews.com/research/Solitons-could-power-molecular-electronics-artificial-muscles_46501.shtml Latest Research Columbus, Ohio -- Scientists have discovered something new about exotic particles called solitons. Thu, 06 Jul 2006 04:00:00 PST http://www.rxpgnews.com/research/Solitons-could-power-molecular-electronics-artificial-muscles_46501.shtml http://www.rxpgnews.com/musculoskeletal/Fibromyalgia_often_misdiagnosed_in_pregnant_women_4647_4647.shtml Musculoskeletal Pregnant women with fibromyalgia (FM) experience significant pain, fatigue and psychological stress, symptoms that are often misdiagnosed or undertreated as a normal part of pregnancy, according to a pilot study by Karen M. Schaefer, D.N.Sc., R.N., assistant professor of nursing at Temple University's College of Health Professions. Thu, 06 Jul 2006 02:58:00 PST http://www.rxpgnews.com/musculoskeletal/Fibromyalgia_often_misdiagnosed_in_pregnant_women_4647_4647.shtml http://www.rxpgnews.com/musculardystrophies/Valproate_effective_in_adult_spinal_muscular_atrop_4541_4541.shtml Muscular Dystrophies An epilepsy drug that has been on the market for decades can ease the symptoms of adult sufferers with a genetic disorder that seriously weakens muscles. Scientists at Washington University School of Medicine in St. Louis retrospectively reviewed results from off-label use of the drug valproate to treat seven adult spinal muscular atrophy (SMA) patients. Clinicians offered the drug to patients on the basis of research conducted elsewhere that showed the drug increased levels of a key protein in cell cultures. Sat, 24 Jun 2006 03:00:00 PST http://www.rxpgnews.com/musculardystrophies/Valproate_effective_in_adult_spinal_muscular_atrop_4541_4541.shtml http://www.rxpgnews.com/musculoskeletal/Cherry_Juice_May_Prevent_Muscle_Damage_Pain_4532_4532.shtml Musculoskeletal The familiar "no pain, no gain" phrase usually associated with exercise may be a thing of the past if results from a study on cherry juice published today in the online version of the British Journal of Sports Medicine prove true in future research. Fri, 23 Jun 2006 00:03:00 PST http://www.rxpgnews.com/musculoskeletal/Cherry_Juice_May_Prevent_Muscle_Damage_Pain_4532_4532.shtml http://www.rxpgnews.com/musculoskeletal/Natural_pine_bark_extract_Pycnogenol_relieves_musc_4480_4480.shtml Musculoskeletal A study published in this month's issue of Angiology shows that supplementation with the pine bark extract Pycnogenol® (pic-noj-en-all) improves blood flow to the muscles which speeds recovery after physical exercise. The study of 113 participants demonstrated that Pycnogenol significantly reduces muscular pain and cramps in athletes and healthy, normal individuals. Sat, 17 Jun 2006 01:41:00 PST http://www.rxpgnews.com/musculoskeletal/Natural_pine_bark_extract_Pycnogenol_relieves_musc_4480_4480.shtml http://www.rxpgnews.com/research/Ninety-six-percent-of-minimally-invasive-knee-replacement-patients-leave-same-day-no-complication_47625.shtml Latest Research Lead author surgeon Richard A. Berger says it's not just the surgeon's skills and techniques that help patients avoid a hospital stay. Mon, 19 Dec 2005 05:00:00 PST http://www.rxpgnews.com/research/Ninety-six-percent-of-minimally-invasive-knee-replacement-patients-leave-same-day-no-complication_47625.shtml http://www.rxpgnews.com/musculardystrophies/Muscular_dystrophy_-_early_cardiac_screening_shows_2750_2750.shtml Muscular Dystrophies Cardiac disease, particularly dilated cardiomyopathy and heart failure, is the major cause of mortality in patients with muscular dystrophy.Intervention with ACE inhibitor or beta blocker therapy improves heart size and function. Sun, 30 Oct 2005 15:02:00 PST http://www.rxpgnews.com/musculardystrophies/Muscular_dystrophy_-_early_cardiac_screening_shows_2750_2750.shtml http://www.rxpgnews.com/pagetsdisease/Single_Infusion_of_Zoledronic_Acid_More_Effective__2305_2305.shtml Pagets Disease A head-to-head study published in The New England Journal of Medicine reports that a single infusion of the investigational bisphosphonate, zoledronic acid 5 mg solution, offers superior efficacy, longer period of remission, and faster onset of action compared to the oral bisphosphonate risedronate (Actonel®) in patients with PagetÂ’s disease. Thu, 08 Sep 2005 01:08:00 PST http://www.rxpgnews.com/pagetsdisease/Single_Infusion_of_Zoledronic_Acid_More_Effective__2305_2305.shtml http://www.rxpgnews.com/pagetsdisease/Studies_confirm_new_treatments_for_Paget_s_disease_2251_2251.shtml Pagets Disease Two studies led by researchers at The University of Auckland's Faculty of Medical and Health Sciences have pioneered new, more effective treatment for two forms of Paget's disease - a chronic and often painful bone disease. Mon, 05 Sep 2005 23:56:00 PST http://www.rxpgnews.com/pagetsdisease/Studies_confirm_new_treatments_for_Paget_s_disease_2251_2251.shtml http://www.rxpgnews.com/musculardystrophies/Gene_therapy_success_for_congenital_muscular_dystr_2075_2075.shtml Muscular Dystrophies Researchers from the University of Pittsburgh report the first study to achieve success with gene therapy for the treatment of congenital muscular dystrophy (CMD) in mice, demonstrating that the formidable scientific challenges that have cast doubt on gene therapy ever being feasible for children with muscular dystrophy can be overcome. Moreover, their results, published in this week's online edition of the Proceedings of the National Academy of Sciences (PNAS), indicate that a single treatment can have expansive reach to muscles throughout the body and significantly increase survival. Tue, 16 Aug 2005 19:46:00 PST http://www.rxpgnews.com/musculardystrophies/Gene_therapy_success_for_congenital_muscular_dystr_2075_2075.shtml http://www.rxpgnews.com/falls/Avoid_Falls_2049_2049.shtml Falls Whether it is caused by a wet floor, slippery throw rug, loose cord or objects in the wrong spot, falls in the home happen. The truth is, falls are not only the most common cause of injury among American adults age 65 and over, but are also the leading cause of death in the home, according to the National Safety Council. Fri, 12 Aug 2005 00:26:00 PST http://www.rxpgnews.com/falls/Avoid_Falls_2049_2049.shtml http://www.rxpgnews.com/falls/Genes_may_ultimately_dictate_seniors_mobility_2263_2263.shtml Falls Genes can keep elderly people from benefiting equally from exercise, no matter how much effort they expend, according to research findings published in today's (Aug. 10) Journal of the American Medical Association. Wed, 10 Aug 2005 00:28:00 PST http://www.rxpgnews.com/falls/Genes_may_ultimately_dictate_seniors_mobility_2263_2263.shtml http://www.rxpgnews.com/falls/Frequent_falls_Try_Tai_Chi_1774_1774.shtml Falls Falls are a major problem in the elderly and form a substantial proportion of the admissions in hospitals. Older people who took part in a structured programme of Tai Chi found that their balance and physical strength improved, reducing the risk of falls, according to a paper in the latest Journal of Advanced Nursing. Tue, 28 Jun 2005 00:24:00 PST http://www.rxpgnews.com/falls/Frequent_falls_Try_Tai_Chi_1774_1774.shtml http://www.rxpgnews.com/pagetsdisease/European_Commission_Approves_Zoledronic_acid_for_t_1215_1215.shtml Pagets Disease Novartis Pharma AG announced today that Aclasta® (zoledronic acid 5mg solution for infusion) has been granted Marketing Authorization by the European Commission for the treatment of Paget's disease of the bone in all 25 European member states, as well as Norway and Iceland. This represents the first approval for Aclasta. Sun, 24 Apr 2005 08:13:00 PST http://www.rxpgnews.com/pagetsdisease/European_Commission_Approves_Zoledronic_acid_for_t_1215_1215.shtml