http://www.rxpgnews.com/ Medical News and Information Thu, 25 Oct 2007 07:48:36 PST en-us http://www.rxpgnews.com/smallpox/Mass_vaccination_would_not_be_necessary_in_the_eve_5072_5072.shtml Small Pox Mass vaccination would not be necessary in the event of a large-scale smallpox bioterrorist attack in the United States, according to a study led by researchers at Fred Hutchinson Cancer Research Center that appears online in the International Journal of Infectious Diseases. Tue, 17 Oct 2006 02:07:00 PST http://www.rxpgnews.com/smallpox/Mass_vaccination_would_not_be_necessary_in_the_eve_5072_5072.shtml http://www.rxpgnews.com/smallpox/Research_suggests_therapy_against_serious_side_eff_3725_3725.shtml Small Pox Smallpox is considered a potential terrorist weapon, but millions of people in the United States are currently advised not to get a vaccine to the disease because they are susceptible to developing a severe adverse reaction. Researchers at National Jewish Medical and Research Center report in the March issue of Immunity that a deficiency in the innate immune response may pre-dispose patients with atopic dermatitis, or eczema, to developing the skin condition eczema vaccinatum after vaccination. The findings suggest potential therapeutic targets, which may reduce the risk of this devastating side effect. Wed, 22 Mar 2006 01:34:00 PST http://www.rxpgnews.com/smallpox/Research_suggests_therapy_against_serious_side_eff_3725_3725.shtml http://www.rxpgnews.com/smallpox/Defective_immune_system_response_to_smallpox_vacci_3723_3723.shtml Small Pox Scientists supported by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), have identified a defect in the immune response of people with the skin condition atopic dermatitis that puts them at risk of developing serious complications following smallpox vaccination. Led by Donald Y.M. Leung, M.D., Ph.D., of the National Jewish Medical and Research Center in Denver, the researchers used laboratory-grown human skin cells to show that an immune system protein called LL-37 is critical in controlling replication of vaccinia virus, the live virus that is the key component in standard smallpox vaccine. Wed, 22 Mar 2006 01:29:00 PST http://www.rxpgnews.com/smallpox/Defective_immune_system_response_to_smallpox_vacci_3723_3723.shtml http://www.rxpgnews.com/smallpox/Secret_of_smallpox_s_success_may_lead_to_bioterror_1534_1534.shtml Small Pox By manipulating what is perhaps the most devastating trick in cellular weaponry of pox viruses like smallpox, Arizona State University virologist and Biodesign Institute researcher Bertram Jacobs believes that he can turn the biochemical machinery of the pox viruses against themselves – and protect the public against catastrophic bioterror attacks. Sun, 22 May 2005 14:33:00 PST http://www.rxpgnews.com/smallpox/Secret_of_smallpox_s_success_may_lead_to_bioterror_1534_1534.shtml