XML Feed for RxPG News   Add RxPG News Headlines to My Yahoo!   Javascript Syndication for RxPG News

Research Health World General
 
  Home
 
 Latest Research
 Cancer
 Psychiatry
 Genetics
  X Chromosome
  Genetic Disorders
  Cloning
 Surgery
 Aging
 Ophthalmology
 Gynaecology
 Neurosciences
 Pharmacology
 Cardiology
 Obstetrics
 Infectious Diseases
 Respiratory Medicine
 Pathology
 Endocrinology
 Immunology
 Nephrology
 Gastroenterology
 Biotechnology
 Radiology
 Dermatology
 Microbiology
 Haematology
 Dental
 ENT
 Environment
 Embryology
 Orthopedics
 Metabolism
 Anaethesia
 Paediatrics
 Public Health
 Urology
 Musculoskeletal
 Clinical Trials
 Physiology
 Biochemistry
 Cytology
 Traumatology
 Rheumatology
 
 Medical News
 Health
 Opinion
 Healthcare
 Professionals
 Launch
 Awards & Prizes
 
 Careers
 Medical
 Nursing
 Dental
 
 Special Topics
 Euthanasia
 Ethics
 Evolution
 Odd Medical News
 Feature
 
 World News
 Tsunami
 Epidemics
 Climate
 Business
Search

Last Updated: Nov 17th, 2006 - 22:35:04

Genetics Channel
subscribe to Genetics newsletter

Latest Research : Genetics

   DISCUSS   |   EMAIL   |   PRINT
New Gene for Charcot-Marie-Tooth Disease Involved in Cell Transport
Apr 13, 2005, 00:21, Reviewed by: Dr.

In this study, an international team of researchers identified the responsible gene as Dynamin 2 (DNM2), whose protein helps cell membranes fuse together and separate.

 
Charcot-Marie-Tooth disease (CMT), which affects the peripheral nerves, comes in several forms and is due to mutation in a variety of genes.

Autosomal dominant CMT of the so-called intermediate form has previously been linked to chromosome 19.

In this study, an international team of researchers identified the responsible gene as Dynamin 2 (DNM2), whose protein helps cell membranes fuse together and separate. The mutation, found in several families from North America, Australia, and Belgium, impairs a variety of critical cell transport processes.

In addition, neutropenia, a white blood cell disorder, was found to be inherited along with the disease, which has not been seen in CMT families before. The same protein function that is impaired by the mutation--the ability to bind a high-energy molecule called CTP--is also impaired by other CMT gene mutations, suggesting this may be a central pathway for a large class of peripheral neuropathies.
 

- American Academy of Neurology 57th Annual Meeting held in Miami Beach, Fla., April 9 � 16, 2005.
 

www.aan.com

 
Subscribe to Genetics Newsletter
E-mail Address:

 

The American Academy of Neurology, an association of more than 18,000 neurologists and neuroscience professionals, is dedicated to improving patient care through education and research. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer's disease, epilepsy, multiple sclerosis, Parkinson's disease, and stroke.

For more information about the American Academy of Neurology, visit www.aan.com.


Related Genetics News

New research into csd genes could help designing strategies for breeding honey bees
Williams Syndrome, the brain and music
Genetic mutation identified as cause of cranio-lenticulo-sutural dysplasia
Chance Fluctuations in mRNA Output in Mammalian Cells
Transposon Silencing Keeps Jumping Genes in Their Place
GATA2 - predicting susceptibility to coronary artery disease
Exploring genetics of congenital malformations
Genome insertions and deletions (INDELs) provide expanded view of human genetic differences
BRIT1 gene identified as protector of DNA
FDA Approves Idursulfase As First Treatment for Hunter Syndrome


For any corrections of factual information, to contact the editors or to send any medical news or health news press releases, use feedback form

Top of Page

 

© Copyright 2004 onwards by RxPG Medical Solutions Private Limited
Contact Us