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Last Updated: May 10, 2008 - 3:38:29 AM |
Latest Research
Suspected cause of type 1 diabetes caught 'red-handed' for the first time
May 8, 2008 -- Scientists at Washington University School of Medicine in St. Louis working with diabetic mice have examined in unprecedented detail the immune cells long thought to be responsible for type 1 diabetes.
May 9, 2008 - 4:00:00 AM
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Latest Research
Harmful blood glucose levels linked to defective gene
A genetic mutation that can raise the amount of glucose in a person's
blood to harmful levels is identified today in a study in the journal
Science.
May 1, 2008 - 4:00:00 AM
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Latest Research
Researchers uncover new genetic links to psoriasis
In the first comprehensive study of the genetic basis of psoriasis, researchers at Washington University School of Medicine in St. Louis have discovered seven new sites of common DNA variation that increase the risk of the troublesome skin condition. They also found that variations in one genetic region link psoriasis and a related joint disorder, psoriatic arthritis, to four autoimmune diseases: type 1 diabetes, Grave's disease, celiac disease and rheumatoid arthritis.
Apr 3, 2008 - 4:00:00 AM
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Latest Research
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Endocrinology
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Diabetes
How diabetes accelerates atherosclerosis
Researchers have discovered how diabetes, by driving inflammation and slowing blood flow, dramatically accelerates atherosclerosis, according to research to be published in the March 14 edition of the journal Circulation Research.
Mar 13, 2008 - 10:12:00 AM
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Latest Research
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Endocrinology
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Diabetes
CRTC2 inhibitors may be needed for maintaining sugar levels
Continually revved up insulin production, the kind that results from overeating and obesity, slowly dulls the body’s response to insulin. As a result, blood sugar levels start to creep up, setting the stage for diabetes-associated complications such as blindness, stroke and renal failure. To make matters even worse, chronically elevated blood sugar concentrations exacerbate insulin resistance.
Mar 9, 2008 - 6:57:23 AM
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Latest Research
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Endocrinology
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Diabetes
A focus on the ADVANCE and RISC studies in the Diabetes UK conference March 2008
In the recent Annual Professional Conference held in Glasgow(March 5-7, 2008) an interesting talk was on the late breaking trials. There was a focus on the ADVANCE trial (presented by Dr Neil Poulter, London) and the RISC trial (presented by Dr Mark Walker, Newcastle). Here is a brief overview of the studies and the thoughts of the speakers and audience.
Mar 8, 2008 - 7:22:07 AM
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Latest Research
Type 2 diabetes may be caused by intestinal dysfunction
NEW YORK (March 5, 2008) -- Growing evidence shows that surgery may effectively cure Type 2 diabetes -- an approach that not only may change the way the disease is treated, but that introduces a new way of thinking about diabetes.
Mar 5, 2008 - 5:00:00 AM
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Latest Research
Protein target for diabetes drug regulates blood pressure
University of Iowa researchers have identified a molecular pathway in blood vessels that controls blood pressure and vascular function and may help explain why certain drugs for type II diabetes also appear to lower patients' blood pressure. The study is published in the March 5 issue of Cell Metabolism.
Mar 4, 2008 - 5:00:00 AM
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Latest Research
Rare syndrome provides clues on obesity, blood pressure
University of Iowa researchers have found a clue about how resistance to the hormone leptin might disrupt the brain signals that tell the body when to stop eating. The research, which focused on the rare genetic disorder Bardet-Biedl syndrome (BBS), also found an association between leptin resistance and high blood pressure.
Mar 3, 2008 - 5:00:00 AM
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Latest Research
Study: highly involved patients don't always see better health outcomes
Patients who prefer to be highly involved in their treatment don't necessarily have better luck managing chronic health conditions, a new study suggests.
Feb 22, 2008 - 5:00:00 AM
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Latest Research
Intensive blood sugar treatment in trial of diabetes and cardiovascular disease changed
The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health has stopped one treatment within a large, ongoing North American clinical trial of diabetes and cardiovascular disease 18 months early due to safety concerns after review of available data, although the study will continue.
Feb 6, 2008 - 11:40:00 PM
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Latest Research
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Endocrinology
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Diabetes
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Insulin Resistance
Insulin inhibits resistin expression and secretion
Does resistin play a role in insulin resistance? Is insulin the major regulator of resistin? A research article to be published on January 7, 2008 in the World Journal of Gastroenterology (volume 14, issue 1) addresses these questions.
Jan 16, 2008 - 2:07:29 PM
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Latest Research
Overweight people may not know when they've had enough
UPTON, NY - Researchers at the U.S. Department of Energy's Brookhaven National Laboratory have found new clues to why some people overeat and gain weight while others don't. Examining how the human brain responds to satiety messages delivered when the stomach is in various stages of fullness, the scientists have identified brain circuits that motivate the desire to overeat. Treatments that target these circuits may prove useful in controlling chronic overeating, according to the authors. The study is published online and will appear in the February 15, 2008 issue of NeuroImage.
Jan 9, 2008 - 5:00:00 AM
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Latest Research
Oral anti diabetic substance discovered
Research in the Department of Biology at the Faculty of Science and Science Education of the University of Haifa has discovered a substance that may become an oral treatment for diabetes and its complications. The substance, which is derived from yeast, is called Glucose Tolerance Factor (GTF). The research is now at the stage where the substance has been successfully tested on diabetic rats and was found to reduce sugar and lipids in the blood of the treated animals. The next stage of the research is to evaluate GTF efficacy in humans, said Dr. Nitsa Mirsky, who is conducting the research.
Dec 24, 2007 - 5:00:00 AM
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Latest Research
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Endocrinology
Melatonin could hurt memory formation at night
In a study with zebrafish (Danio rerio), Gregg W. Roman, assistant professor in the Department of Biology and Biochemistry at the University of Houston, has found that melatonin directly inhibits memory formation at night.
Nov 15, 2007 - 1:51:41 PM
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Latest Research
Stanford researchers shed light on black box of gestational diabetes
STANFORD, Calif. - A protein in the pancreas is giving researchers at the Stanford University School of Medicine their first chance at cracking the code that determines how diabetes develops during pregnancy, a finding that could lead to new treatments for all forms of diabetes.
Nov 1, 2007 - 4:00:00 AM
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Latest Research
'Knocking out' cell receptor may help block fat deposits in tissues, prevent weight gain
CINCINNATI—University of Cincinnati (UC) pathologists have identified a new molecular target that one day may help scientists develop drugs to reduce fat transport to adipocytes (fat cells) in the body and prevent obesity and related disorders, like diabetes.
Oct 25, 2007 - 4:00:00 AM
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Latest Research
'Twinkle after effect' can help retinal patients detect vision loss quickly and cheaply
Boston, MA—Scientists at Schepens Eye Research Institute have discovered a simple and inexpensive way for patients with retinal and other eye disease to keep track of changes in their vision loss. In a study published in this week’s PLoS One (October 24, 2007) they demonstrate that a compelling visual illusion known as the induced twinkle after-effect (TAE) can accurately identify the location and breadth of actual blind spots in people with retinal disease. The twinkle after-effect is a “twinkling” that people can see in a blind spot when they stare at a blank screen after staring at a noisy visual target such as a detuned television screen.
Oct 23, 2007 - 4:00:00 AM
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Latest Research
Exercise improves thinking, reduces diabetes risk in overweight children
Just three months of daily, vigorous physical activity in overweight children improves their thinking and reduces their diabetes risk, researchers say.
Oct 22, 2007 - 4:00:00 AM
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Latest Research
Cross-species transplant in rhesus macaques is step toward diabetes cure for humans
St. Louis, Oct. 18, 2007 — With an eye on curing diabetes, scientists at Washington University School of Medicine in St. Louis have successfully transplanted embryonic pig pancreatic cells destined to produce insulin into diabetic macaque monkeys – all without the need for risky immune suppression drugs that prevent rejection.
Oct 18, 2007 - 4:00:00 AM
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Latest Research
Sex hormone signature indicates gender rather than just chromosomes
Help with assigning gender could one day be at hand for intersex individuals whose genital phenotypes and sex chromosomes don't match, thanks to the discovery of a stable sex hormone signature in our cells.
Oct 17, 2007 - 4:00:00 AM
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Latest Research
Insulin's brain impact links drugs and diabetes
Insulin, long known as an important regulator of blood glucose levels, now has a newly appreciated role in the brain.
Oct 16, 2007 - 4:00:00 AM
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Latest Research
Low doses of a red wine ingredient fight diabetes in mice
Even relatively low doses of resveratrol—a chemical found in the skins of red grapes and in red wine—can improve the sensitivity of mice to the hormone insulin, according to a report in the October issue of Cell Metabolism, a Cell Press publication. As insulin resistance is often characterized as the most critical factor contributing to the development of type 2 diabetes, the findings “provide a potential new therapeutic approach for preventing or treating” both conditions, the researchers said.
Oct 2, 2007 - 4:00:00 AM
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Latest Research
Genetic 'roadblock' hoped to inspire future type 2 diabetes research
Toronto, ON (October 2, 2007) – A team of Mount Sinai Hospital researchers has found that a “genetic roadblock” identified in a recent study could pave the way toward novel treatments for type 2 diabetes.
Oct 2, 2007 - 4:00:00 AM
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Latest Research
Botched production of insulin molecule may lead to diabetes
ANN ARBOR, Mich. — Picture a pretzel factory production line, with conveyer belts carrying the dough, formed into unbaked pretzels, down to the oven to be cooked.
Oct 1, 2007 - 4:00:00 AM
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Latest Research
Depression, aging, and proteins made by a virus may all play role in heart disease
COLUMBUS, Ohio – Researchers here have linked an increase in two immune system proteins essential for inflammation to a latent viral infection and proposed a chain of events that might accelerate cardiovascular disease.
Oct 1, 2007 - 4:00:00 AM
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Latest Research
Joslin researchers uncover potential role of leptin in diabetes
BOSTON–October 1, 2007–A new Joslin-led study has shown that leptin, a hormone known mainly for regulating appetite control and energy metabolism, plays a major role in islet cell growth and insulin secretion. This finding opens up new avenues for studying leptin and its role in islet cell biology, which may lead to new treatments for diabetes. This study appears in the October 2007 issue of The Journal of Clinical Investigation.
Oct 1, 2007 - 4:00:00 AM
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Latest Research
'Bad carbs' not the enemy, University of Virginia professor finds
The latest common wisdom on carbohydrates claims that eating so-called “bad” carbohydrates will make you fat, but University of Virginia professor Glenn Gaesser says, “that’s just nonsense.” Eating sandwiches with white bread, or an occasional doughnut, isn't going to kill you, or necessarily even lead to obesity, he said.
Sep 28, 2007 - 4:00:00 AM
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Latest Research
Discovery supports theory of Alzheimer's disease as form of diabetes
EVANSTON, Ill. --- Insulin, it turns out, may be as important for the mind as it is for the body. Research in the last few years has raised the possibility that Alzheimer’s memory loss could be due to a novel third form of diabetes.
Sep 26, 2007 - 4:00:00 AM
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Latest Research
Consumption of omega-3 fatty acids associated with decreased risk of type 1 diabetes
Preliminary research suggests that in children at increased risk for type 1 diabetes, dietary intake of omega-3 fatty acids was associated with a reduced risk of pancreatic islet autoimmunity, which is linked to the development of diabetes, according to an article in the Sept. 26 issue of JAMA.
Sep 25, 2007 - 4:00:00 AM
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Latest Research
Breath analysis offers potential for noninvasive blood sugar monitoring in diabetes
Irvine, Calif. — Breath-analysis testing may prove to be an effective, non-invasive method for monitoring blood sugar levels in diabetes, according to a University of California, Irvine study.
Sep 24, 2007 - 4:00:00 AM
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Latest Research
Brain system serves as 'remote control' for fat metabolism
CINCINNATI—A system in the brain already known to regulate food intake also serves as a direct “remote control” for the way fat is stored and metabolized in the body, say University of Cincinnati (UC) researchers.
Sep 20, 2007 - 4:00:00 AM
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Latest Research
Cedars-Sinai hormone expert outlines causes and treatments for breast growth in men in NEJM
LOS ANGELES (September 14, 2007) Gynecomastia, the benign enlargement of male breast tissue, is a common occurrence in adolescents as well as in middle-aged and older men. While there are several reasons why men develop breast tissue, it is usually not a health concern, often resolves on its own, and is generally treatable, according to a clinical practice article appearing in the September 20 issue of the New England Journal of Medicine (NEJM).
Sep 19, 2007 - 4:00:00 AM
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Latest Research
Both aerobic and resistance exercise improved blood sugar control in people with diabetes
In a new randomized controlled trial, both aerobic and resistance exercise improved glycemic/blood sugar control in people with type 2 diabetes. The greatest improvements came from combined aerobic and resistance training.
Sep 17, 2007 - 4:00:00 AM
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Latest Research
Immune police recognize good and bad guys in the body
Immune system police are as good at recognizing bad guys, such as bacteria and viruses, as they are our own tissue, researchers say.
Sep 14, 2007 - 4:00:00 AM
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Latest Research
Long-term use of diabetes drug increases heart attack risk by more than 40 percent
WINSTON-SALEM, N.C. – An analysis of four studies involving more than 14,000 patients found that long-term use of the diabetes drug rosiglitazone (Avandia®) increased the risk of heart attack by 42 percent and doubled the risk of heart failure, according to a new report from researchers at Wake Forest University School of Medicine and colleagues. There was no effect on death from cardiovascular causes.
Sep 11, 2007 - 4:00:00 AM
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Latest Research
Children who learn heart healthy eating habits lower heart disease risk
A new study in a mid-August edition of Circulation: Journal of the America Heart Association confirms that when young children learn about heart healthy eating habits, it can strongly influence their heart disease risk later in life.
Sep 11, 2007 - 4:00:00 AM
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Latest Research
Scientists learn role of oxidative stress in estrogen-related bone loss
Scientists have discovered new information about an immune pathway in mice that explains how oxidative stress that results from acute estrogen deficiency leads to the loss of bone. The finding, published in the Proceedings of the National Academy of Sciences, could help in identifying a new drug target for preventing postmenopausal bone loss.
Sep 10, 2007 - 4:00:00 AM
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Latest Research
Mutations in the insulin gene can cause neonatal diabetes
Mutations in the insulin gene can cause permanent neonatal diabetes, an unusual form of diabetes that affects very young children and results in lifelong dependence on insulin injections, report researchers from the University of Chicago and Peninsula University (Exeter, UK) in Sept. 18, 2007, issue of the Proceedings of the National Academy of Sciences, published early online.
Sep 10, 2007 - 4:00:00 AM
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Latest Research
Low vitamin D during pregnancy linked to pre-eclampsia
PITTSBURGH, Sept. 7 – Vitamin D deficiency early in pregnancy is associated with a five-fold increased risk of preeclampsia, according to a study from the University of Pittsburgh Schools of the Health Sciences reported this week in the Journal of Clinical Endocrinology and Metabolism.
Sep 7, 2007 - 4:00:00 AM
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Latest Research
Drug could improve pregnancy outcomes in wider range of women with insulin resistance
St. Louis, Sept. 6, 2007 — Women who are obese, have type 2 diabetes or a family history of type 2 diabetes could one day have more successful pregnancies because of a study at Washington University School of Medicine in St. Louis.
Sep 6, 2007 - 4:00:00 AM
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Latest Research
Sugary drinks, not fruit juice, may be linked to insulin
BOSTON (Sept. 5, 2007) — Steady increases in consumption of sugar-sweetened beverages over the last several decades, as well as rates of Type 2 diabetes mellitus, led nutritional epidemiologists at the Jean Mayer USDA Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University and colleagues to explore the relationship between sugar-sweetened beverage consumption and insulin resistance, a precursor to Type 2 diabetes. Their findings suggest that higher consumption of sugar-sweetened drinks, but not 100 percent fruit juice, may be associated with insulin resistance, even in otherwise healthy adults.
Sep 5, 2007 - 4:00:00 AM
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Latest Research
Environmental stress probed in cardiovascular disease, diabetes
How environmental stress contributes to cardiovascular disease and type II diabetes is under study at the Medical College of Georgia.
Sep 5, 2007 - 4:00:00 AM
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Latest Research
How insulin TORC2 blood sugar levels: glowing mice light the way
La Jolla, CA — With the help of genetically engineered mice whose livers turned into glowing light bulbs, researchers at the Salk Institute for Biological Studies have illuminated the underpinnings of an insidious and growing health concern— type II diabetes.
Sep 5, 2007 - 4:00:00 AM
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Latest Research
Mice stressed in simulated weightlessness show organ atrophy
New Brunswick, N.J. – A ground-based, experimental model used to simulate astronaut weightlessness in space has provided Rutgers scientists an opportunity to study the effects of stress on immune organs.
Sep 3, 2007 - 4:00:00 AM
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Latest Research
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Endocrinology
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Diabetes
Combination drug therapy for blood pressure may reduce cardiovascular outcomes for diabetes patients
By 2030, an estimated 350 million people will be living with diabetes worldwide. Individuals with type 2 diabetes are at an increased risk of cardiovascular outcomes including heart attack, stroke, and microvascular outcomes such as degenerative eye disease. Current guidelines recommend the lowering of blood pressure for people with type 2 diabetes to reduce the risk of such events, though a strategy to reduce blood pressure regardless of baseline blood pressure (ie, including people with diabetes who do not have raised blood pressure) has not been proven in randomised trials to date.
Sep 2, 2007 - 4:00:00 AM
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Latest Research
Treating diabetes during pregnancy can break link to childhood obesity
August 28, 2007 (Oakland, Calif) -- Treating diabetes during pregnancy can break the link between gestational diabetes and childhood obesity, according to a Kaiser Permanente study featured in the September issue of Diabetes Care.
Aug 28, 2007 - 4:00:00 AM
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Latest Research
Novel method enables genomic screening of blood vessels from patient tissue
COLUMBUS, Ohio – Scientists have developed a new method of capturing a complete genome-wide screening of blood vessel cells in their actual disease state, advancing the potential for genetic research on the tissue responsible for delivering nourishment that can accelerate the growth of both a cancer tumor or wound healing.
Aug 28, 2007 - 4:00:00 AM
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Latest Research
Focus on families aims to curb diabetes spread
Family lifestyles and their impact on the health of individual family members will be the focus of a new approach to preventing diabetes.
Aug 22, 2007 - 4:00:00 AM
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Latest Research
New Joslin research identifies sirtuin protein instrumental in fat production and metabolism
BOSTON--August 15, 2007--A new Joslin Diabetes Center-led study has identified a protein found in fat cells that may play a major role in how fat is produced and stored, offering a new target for treatments to prevent obesity and reduce the risk for type 2 diabetes. This latest research appears in the August 2007 issue of Cell Metabolism.
Aug 15, 2007 - 4:00:00 AM
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