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Last Updated: Jan 12, 2012 - 1:31:26 AM |
Latest Research
Best way to boost adult immunizations is through office-based action, study finds
Promoting immunizations as a part of routine office-based medical practice is needed to improve adult vaccination rates, a highly effective way to curb the spread of diseases across communities, prevent needless illness and deaths, and lower health care costs, according to a new RAND Corporation study.
Jan 11, 2012 - 5:00:00 AM
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Latest Research
Scientists identify cell death pathway involved in lethal sepsis
Sepsis, a form of systemic inflammation, is the leading cause of death in critically ill patients. Sepsis is linked with massive cell death; however, the specific mechanisms involved in the lethality of sepsis are unclear. Now, a new study published by Cell Press in the December 23rd issue of the journal Immunity finds that inhibition of a specific cell death pathway called necroptosis protected mice from lethal inflammation. The research may lead to new therapeutic interventions for fatal inflammatory conditions that are notoriously hard to control.
Dec 22, 2011 - 5:00:00 AM
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Latest Research
'Pep talk' can revive immune cells exhausted by chronic viral infection
Chronic infections by viruses such as HIV or hepatitis C eventually take hold because they wear the immune system out, a phenomenon immunologists describe as exhaustion.
Dec 13, 2011 - 5:00:00 AM
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Latest Research
Chief scientific officer named first Richard L. Menschel Research Chair at Special Surgery
Steven R. Goldring, M.D., chief scientific officer, has been named the first Richard L. Menschel Research Chair at Hospital for Special Surgery. A gift of $5 million from an anonymous donor will permanently endow the position of the Hospital's chief scientific officer.
Dec 13, 2011 - 5:00:00 AM
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Latest Research
Risk of contracting diabetes to increase in world of 7 billion people
World citizen number 7 billion is less likely to die from infectious diseases like measles or even AIDS, and more likely to contract diabetes or other non-communicable diseases (NCDs), as they are now the leading causes of deaths globally.
Nov 14, 2011 - 5:00:00 AM
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Latest Research
Study finds shifting disease burden following universal Hib vaccination
[EMBARGOED FOR NOV. 11, 2011] Vaccination against Haemophilus influenzae type b, or Hib, once the most common cause of bacterial meningitis in children, has dramatically reduced the incidence of Hib disease in young children over the past 20 years, according to a study published in Clinical Infectious Diseases and available online (
Nov 11, 2011 - 5:00:00 AM
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Latest Research
Rheumatoid arthritis patients have low expectations after knee replacement surgery
Compared with osteoarthritis patients, individuals with rheumatoid arthritis who undergo total knee replacement surgery have lower expectations about their postsurgical outcomes, according to a new study by researchers at Hospital for Special Surgery (HSS) in New York City. These reduced expectations, which may be unnecessary, could cause some patients to slack on their postsurgical rehabilitation leading to worse outcomes, say doctors. The study will be presented November 7 at the annual meeting of the American College of Rheumatology.
Nov 5, 2011 - 4:00:00 AM
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Latest Research
Hospital for special surgery physician-scientists share advances in rheumatology research
Hospital for Special Surgery physician-scientists who focus on arthritis, lupus, vasculitis and related conditions are traveling from New York City to Chicago this week to share their recent findings at the 75th Annual Scientific Meeting of the American College of Rheumatology (ACR).
Nov 5, 2011 - 4:00:00 AM
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Latest Research
Stress triggers disease flares in patients with vasculitis
In patients with a devastating form of vasculitis who are in remission, stress can be associated with a greater likelihood of the disease flaring, according to a new study by investigators at Hospital for Special Surgery (HSS).
Nov 5, 2011 - 4:00:00 AM
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Latest Research
Dirt prevents allergy
Oversensitivity diseases, or allergies, now affect 25 per cent of the population of Denmark. The figure has been on the increase in recent decades and now researchers at the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), University of Copenhagen, are at last able to partly explain the reasons.
Nov 2, 2011 - 4:00:00 AM
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Latest Research
Natural killer cells could be key to anthrax defense
GALVESTON, Texas -- One of the things that makes inhalational anthrax so worrisome for biodefense experts is how quickly a relatively small number of inhaled anthrax spores can turn into a lethal infection. By the time an anthrax victim realizes he or she has something worse than the flu and seeks treatment, it's often too late; even the most powerful antibiotics may be no help against the spreading bacteria and the potent toxins they generate.
Oct 27, 2011 - 4:00:00 AM
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Latest Research
A*STAR scientists first to identify stem cell key to lung regeneration
Scientists at A*STAR'S Genome Institute of Singapore (GIS) and Institute of Molecular Biology (IMB), have made a breakthrough discovery in the understanding of lung regeneration. Their research showed for the first time that distal airway stem cells (DASCs), a specific type of stem cells in the lungs, are involved in forming new alveoli to replace and repair damaged lung tissue, providing a firm foundation for understanding lung regeneration.
Oct 27, 2011 - 4:00:00 AM
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Latest Research
Brain immune cells respond to alcohol
When you think about your immune system, you probably think about it fighting off a cold. But new research from the University of Adelaide suggests that immune cells in your brain may contribute to how you respond to alcohol.
Sep 29, 2011 - 4:00:00 AM
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Latest Research
NIH modifies 'VOICE' HIV prevention study in women
A large-scale clinical trial evaluating whether daily use of an oral tablet or vaginal gel containing antiretroviral drugs can prevent HIV infection in women is being modified because an interim review found that the study cannot show that one of the study products, oral tenofovir, marketed under the trade name Viread, is effective.
Sep 28, 2011 - 4:00:00 AM
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Latest Research
New evidence highlights risk of comorbidities for COPD patients
Amsterdam, The Netherlands: A new study has shown that people with chronic obstructive pulmonary disease (COPD) or people with reduced lung function are at a serious risk of developing cardiovascular disease.
Sep 26, 2011 - 4:00:00 AM
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Latest Research
Scientists disarm HIV in step towards vaccine
Researchers have found a way to prevent HIV from damaging the immune system, in a new lab-based study published in the journal Blood. The research, led by scientists at Imperial College London and Johns Hopkins University, could have important implications for the development of HIV vaccines.
Sep 19, 2011 - 4:00:00 AM
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Latest Research
T cells making brain chemicals may lead to better treatments for inflammation, autoimmune diseases
MANHASSET, NY -- Scientists have identified a surprising new role for a new type of T cell in the immune system: some of them can be activated by nerves to make a neurotransmitter (acetylcholine) that blocks inflammation. The discovery of these T cells is novel and suggests that it may be possible to treat inflammation and autoimmune diseases by targeting the nerves and the T cells. The study was published this week in Science.
Sep 16, 2011 - 4:00:00 AM
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Latest Research
Pharmacists need to provide better information to teenagers on risks and benefits of medicines
Hyderabad, India: A large proportion of teenagers regularly and frequently take some form of medication without receiving targeted information about the risks and benefits, according to a review of current research, to be presented at the annual congress of the International Pharmaceutical Federation (FIP) tomorrow (Tuesday).
Sep 4, 2011 - 4:00:00 AM
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Latest Research
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Physiotherapy
Achieving realistic physical activity goals benefits RA patients
Researchers from The Netherlands report that patients with rheumatoid arthritis (RA) who have higher levels of self-efficacy for physical activity are more likely to achieve their physical activity goals. According to the study now available in Arthritis Care & Research, a journal of the American College of Rheumatology (ACR), achievement of physical activity goals is associated with lower self-reported arthritis pain and increased health-related quality of life (HRQOL).
Aug 25, 2011 - 4:00:00 AM
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Latest Research
Researchers on the trail of a treatment for cancer of the immune system
Infection with Epstein Barr means that the B cells, which are the primary memory cells of the immune system, are hi-jacked.
Aug 19, 2011 - 4:00:00 AM
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Latest Research
Trauma drama: K-State professor researches drama queen of immune system
MANHATTAN, KAN. -- Kansas State University's Sherry Fleming is investigating the factor that initiates the immune system's drama queen: the one responsible for intestinal cell damage after hemorrhage.
Aug 8, 2011 - 4:00:00 AM
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Latest Research
NIH funds Emory-led consortium to advance AIDS vaccine research
A consortium of leading vaccine researchers at Emory University and partner institutions has received a National Institutes of Health (NIH) grant aimed at developing an effective HIV/AIDS vaccine.
Jul 18, 2011 - 4:00:00 AM
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Latest Research
Lack of clarity about HPV vaccine and the need for cervical cancer screening
The research will be presented today [Thursday 7 July] at the Annual Scientific Meeting of the Society of Academic Primary Care, hosted this year by the Academic Unit of Primary Health Care, University of Bristol.
Jul 6, 2011 - 4:00:00 AM
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Latest Research
Sport doctors say non-alcoholic wheat beer boosts athletes' health
Many amateur athletes have long suspected what research scientists for the Department of Preventative and Rehabilitative Sports Medicine of the Technische Universitaet Muenchen at Klinikum rechts der Isar have now made official: Documented proof, gathered during the world's largest study of marathons, Be-MaGIC (beer, marathons, genetics, inflammation and the cardiovascular system), that the consumption of non-alcoholic weissbier, or wheat beer, has a positive effect on athletes' health. Under the direction of Dr. Johannes Scherr, physicians examined 277 test subjects three weeks before and two weeks after the 2009 Munich Marathon.
Jun 9, 2011 - 4:00:00 AM
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Latest Research
Researchers discover biochemical weakness of malaria parasite -- vaccine to be developed
Every year, 10,000 pregnant women and up to 200,000 newborn babies are killed by the malaria parasite. Doctors all around the globe have for years been looking in vain for a medical protection, and now researchers from the University of Copenhagen have found the biochemically weakness of the lethal malaria parasite, and will now start developing a vaccine to combat pregnancy related malaria.
Jun 7, 2011 - 4:00:00 AM
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Latest Research
Adjuvant combo shows potential for universal influenza vaccine
Researchers at National Jewish Health have discovered how to prime a second arm of the immune system to potentially boost influenza vaccine effectiveness. A combination of two adjuvants, chemicals used to boost the effectiveness of some vaccines, induced CD8, or killer, T cells to join antibodies in response to influenza infection. Since the killer T cells targeted a highly conserved protein that does not change from year to year, the adjuvant strategy suggests potential for a universal flu vaccine.
Jun 7, 2011 - 4:00:00 AM
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Latest Research
Clinical trial of malaria vaccine begins in Africa
The vaccine, RTS,S, developed by GlaxoSmithKline (GSK) Biologicals and PATH Malaria Vaccine Initiative (MVI), is currently in phase III clinical trials and has previously reduced episodes of malaria in infants and young children by more than 50%. The Liverpool team, in collaboration with the University College of Medicine, Malawi, are working in Blantyre over the next three years to investigate how to maximise its effectiveness when delivered through the childhood immunisation programme.
May 25, 2011 - 4:00:00 AM
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Latest Research
New test could give SLE patients a more tolerable life
At present, it can take up to a year before a patient is diagnosed with SLE. This is because the symptoms are diffuse and are often mistaken for other diseases. However, with this blood-based test, it is possible to determine quickly whether someone has the disease or not, says Christer Wingren, associate professor in Immunotechnology at CREATE Health, Lund University.
May 9, 2011 - 4:00:00 AM
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Latest Research
Antibodies help protect monkeys from HIV-like virus, NIH scientists show
WHAT: Using a monkey model of AIDS, scientists have identified a vaccine-generated immune-system response that correlates with protection against infection by the monkey version of HIV, called simian immunodeficiency virus (SIV). The researchers found that neutralizing antibodies generated by immunization were associated with protection against SIV infection. This finding marks an important step toward understanding how an effective HIV vaccine could work, according to scientists who led the study at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.
May 5, 2011 - 4:00:00 AM
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Latest Research
Systematic effort helps hospital raise employee flu vaccination rates
A systematic effort to improve flu vaccination rates for healthcare workers has increased flu vaccinations rates from 59 percent to 77 percent at the University Health System (UHS) in San Antonio. A report detailing their interventions to increase vaccination was published in the June issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.
May 4, 2011 - 4:00:00 AM
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Latest Research
Terry Strom, M.D., honored by International Society of Nephrology
BOSTON -- Terry Strom, MD, Co-director of the Transplant Institute at Beth Israel Deaconess Medical Center (BIDMC) and a leader in the field of immune tolerance research, was awarded the 2011 Alfred Newton Richards Award from the International Society of Nephrology during a program held earlier this month as part of the World Congress of Nephrology 2011 in Vancouver, Canada.
Apr 29, 2011 - 4:00:00 AM
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Latest Research
BIDMC's Peter Weller, M.D., receives NIH MERIT Award
BOSTON -- Peter Weller, MD, Chief of both the Division of Allergy and Inflammation and the Division of Infectious Diseases at Beth Israel Deaconess Medical Center (BIDMC), is the recipient of an NIH MERIT award from the National Institute of Allergy and Infectious Diseases. A Professor of Medicine at Harvard Medical School, Weller received the award for his longstanding grant, Human Eosinophils: Mechanisms of Functioning.
Apr 27, 2011 - 4:00:00 AM
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Latest Research
Nasal spray vaccines more effective against flu
Nasal vaccines that effectively protect against flu, pneumonia and even bioterrorism agents such as Yersinia pestis that causes the plague, could soon be a possibility, according to research presented at the Society for General Microbiology's Spring Conference in Harrogate. Professor Dennis Metzger describes how including a natural immune chemical with standard vaccines can boost their protective effect when delivered through the nose.
Apr 11, 2011 - 4:00:00 AM
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Latest Research
Allergy vaccine is nothing to sneeze at
Monash University researchers are working on a vaccine that could completely cure asthma brought on by house dust mite allergies.
Mar 21, 2011 - 4:00:00 AM
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Latest Research
New vaccine technology protects mice from hepatitis C virus
Immunology: Three percent of the world's population is currently infected by hepatitis C. The virus hides in the liver and can cause cirrhosis and liver cancer, and it's the most frequent cause of liver transplants in Denmark. Since the virus mutates strongly, we have no traditional vaccine, but researchers at the University of Copenhagen are now the first to succeed in developing a vaccine, which provides future hope for medical protection from this type of hepatitis.
Feb 23, 2011 - 5:00:00 AM
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Latest Research
Modell Chair in Pediatric Immunology established
The Children's Hospital of Philadelphia has announced the establishment of the Jeffrey Modell Endowed Chair in Pediatric Immunology Research.
Feb 16, 2011 - 5:00:00 AM
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Latest Research
Saint Louis University findings: Don't pitch stockpiled avian flu vaccine
ST. LOUIS -- A stockpiled vaccine designed to fight a strain of avian flu that circulated in 2004 can be combined with a vaccine that matches the current strain of bird flu to protect against a potential pandemic, researchers from Saint Louis University's Center for Vaccine Development have found.
Feb 9, 2011 - 5:00:00 AM
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Latest Research
Study suggests why HIV-uninfected babies of mothers with HIV might be more prone to infections
Babies whose mothers have HIV, but who are not HIV-infected themselves, are born with lower levels of specific proteins in their blood called antibodies, which fight infection, compared with babies not exposed to HIV, a new study has found. The finding, published today in the Journal of the American Medical Association, might explain in part why uninfected babies born to women with HIV have a higher risk of illness and death early in life.
Feb 8, 2011 - 5:00:00 AM
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Latest Research
Genes of the immune system are associated with increased risk of mental illness
Genes linked to the immune system can affect healthy people's personality traits as well as the risk of developing mental illness and suicidal behaviour, reveals a thesis from the University of Gothenburg, Sweden.
Feb 7, 2011 - 5:00:00 AM
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Latest Research
Patent awarded for method to dampen immune response
National Jewish Health has been issued a US patent claiming a method to desensitize B cells by inactivating antigen receptors on their surfaces. The method, discovered by John Cambier, PhD, Chairman of the Integrated Department of Immunology at National Jewish Health, holds promise for treatment of B-cell mediated diseases, such as lymphoma and leukemia, rheumatoid arthritis, lupus and rejection of organ transplants. This therapeutic approach has the potential advantage of inactivating B cells instead of killing them as current treatments do. Therefore, this potential therapy could be more rapidly adjusted in response to the changing needs of patients.
Jan 18, 2011 - 5:00:00 AM
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Latest Research
Researchers unzip MRSA and discover route for vaccine
University of Rochester Medical Center orthopaedic scientists are a step closer to developing a vaccine to prevent life-threatening methicillin-resistant staphylococcus aureus (MRSA) infections following bone and joint surgery.
Jan 16, 2011 - 5:00:00 AM
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Latest Research
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Immunology
Looking into the immune system of bacteria
Studying how bacteria incorporate foreign DNA from invading viruses into their own regulatory processes, Thomas Wood, professor in the Artie McFerrin Department of Chemical Engineering at Texas A&M University, is uncovering the secrets of one of nature's most primitive immune systems.
Dec 27, 2010 - 10:10:54 AM
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Latest Research
New lung disease network to benefit patients and boost UK economy
Scientists and clinicians in Nottingham are to work more closely with industry to develop new ways of diagnosing and treating lung disease.
Dec 1, 2010 - 5:00:00 AM
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Latest Research
Mother Nature and bioterrorists: Rochester battles both with $11.9 million award
Flu viruses are a great threat, whether they stem from Mother Nature or are modified by human hands to create a deadly bioweapon. The University of Rochester Medical Center will tackle both scenarios head on with a five-year contract, totaling approximately $11.9 million, from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH). The contract will further research into how we can use computer modeling to find ways of boosting human immune responses against and identify new areas of investigation into treatments for a variety of potentially lethal viruses.
Nov 10, 2010 - 5:00:00 AM
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Latest Research
Lupus patients: The doctor, nurse and social worker are here to see you
The benefits of collaborative, multidisciplinary care of patients with complex autoimmune diseases like lupus and multiple sclerosis are just beginning to be appreciated by physicians. Hospital for Special Surgery in New York will present evidence of the advantages of such a specialized disease center dedicated to comprehensive lupus care at the 74th Annual Meeting of the American College of Rheumatology in Atlanta.
Nov 9, 2010 - 5:00:00 AM
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Latest Research
New assessment tool helps shed light on lupus in kids worldwide
A newly designed tool is helping researchers shed light on the quality of life (QoL) of children with lupus around the world, according to research presented at the American College of Rheumatology (ACR) annual meeting, held Nov. 7-11, in Atlanta.
Nov 9, 2010 - 5:00:00 AM
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Latest Research
Hospital for Special Surgery scientists share advances in lupus and related conditions
Hospital for Special Surgery physicians who focus on lupus, scleroderma and related conditions are traveling from New York City to Atlanta this week to share their recent findings at the 74th Annual Scientific Meeting of the American College of Rheumatology (ACR).
Nov 7, 2010 - 4:00:00 AM
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Latest Research
International summit held to stimulate collaborative clinical research on antiphospholipid syndrome
Antiphospholipid Syndrome (APS) is a condition that may be responsible for up to one-third of strokes in people under age 50, up to one-fifth of all cases of blood clots in large veins, and one-quarter of recurrent miscarriages. Nonetheless, relatively few randomized clinical trials have been conducted involving people with APS, and those completed have included small numbers of participants.
Nov 2, 2010 - 4:00:00 AM
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Latest Research
Virginia Bioinformatics Institute to model immune responses to gut pathogens
The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has awarded a $10.6 million grant to researchers at the Virginia Bioinformatics Institute (VBI) and collaborators to determine how the human immune system responds to infection by pathogens of the gut. The funding will be used to apply mathematical modeling to the study of immune responses to gut pathogens.
Oct 8, 2010 - 4:00:00 AM
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Latest Research
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Immunology
Microfluidic tool for isolating neutrophils
A team led by Massachusetts General Hospital (MGH) scientists has developed a new microfluidic tool for quickly and accurately isolating neutrophils – the most abundant type of white blood cell – from small blood samples, an accomplishment that could provide information essential to better understanding the immune system's response to traumatic injury.
Aug 30, 2010 - 9:39:58 AM
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