XML Feed for RxPG News   Add RxPG News Headlines to My Yahoo!   Javascript Syndication for RxPG News

Research Health World General
 
  Home
 
 Latest Research
 Cancer
 Psychiatry
 Genetics
 Surgery
 Aging
 Ophthalmology
 Gynaecology
 Neurosciences
 Pharmacology
 Cardiology
 Obstetrics
 Infectious Diseases
 Respiratory Medicine
  Asthma
  COPD
  Cystic Fibrosis
 Pathology
 Endocrinology
 Immunology
 Nephrology
 Gastroenterology
 Biotechnology
 Radiology
 Dermatology
 Microbiology
 Haematology
 Dental
 ENT
 Environment
 Embryology
 Orthopedics
 Metabolism
 Anaethesia
 Paediatrics
 Public Health
 Urology
 Musculoskeletal
 Clinical Trials
 Physiology
 Biochemistry
 Cytology
 Traumatology
 Rheumatology
 
 Medical News
 Health
 Opinion
 Healthcare
 Professionals
 Launch
 Awards & Prizes
 
 Careers
 Medical
 Nursing
 Dental
 
 Special Topics
 Euthanasia
 Ethics
 Evolution
 Odd Medical News
 Feature
 
 World News
 Tsunami
 Epidemics
 Climate
 Business
Search

Last Updated: Aug 19th, 2006 - 22:18:38

Community-Acquired Pneumonia Recovery in the Elderly (CAPRIE) study

Respiratory Medicine Channel
subscribe to Respiratory Medicine newsletter

Latest Research : Respiratory Medicine

   DISCUSS   |   EMAIL   |   PRINT
CAPRIE study: Moxifloxacin more effective in elders pneumonia
Jan 24, 2006, 23:52, Reviewed by: Dr. Sanjukta Acharya

"The CAPRIE study is very unique in that it was conducted only in patients 65 and older, such as the median age was 78"

 
A newer antibiotic medication proved more effective at knocking out community-acquired pneumonia (CAP) in patients 65 and older than the antibiotic that has been the front-line CAP treatment the last decade, according to a national study coordinated at The University of Texas Health Science Center at San Antonio.

CAP is the fifth-leading cause of death in the elderly, is diagnosed in 5.6 million adults annually in the U.S., and is 60 percent more likely to occur in the elderly than in the general population. The Community-Acquired Pneumonia Recovery in the Elderly (CAPRIE) study, led by Antonio Anzueto, M.D., professor of medicine at the Health Science Center, is reported in the current issue of Clinical Infectious Diseases.

"The CAPRIE study is very unique in that it was conducted only in patients 65 and older, such as the median age was 78," Dr. Anzueto said. "Community-acquired pneumonia is a common infectious disease process in the elderly. Pneumonia has been identified as the leading infectious disease associated with the higher mortality (death) in this age group. This is also the first time the two leading antibiotics for CAP have been compared in a well-controlled clinical trial."

Treated with the newer medication, moxifloxacin HCI, 97.9 percent of hospitalized patients recovered within three to five days of therapy onset, compared to 90 percent of patients treated with the standard medication, levofloxacin. Study findings were in 281 patients at 47 centers.

"At the end of the day, another important question was safety," Dr. Anzueto said. "This study involved very sophisticated assessment of cardiac safety. We found both treatments to be safe." San Antonio patients were treated at the South Texas Veterans Health Care System.

Moxifloxacin HCI's greater efficacy earlier in hospital stays should lead to less occurrence of incapacitating long-term effects, Dr. Anzueto said.

Moxifloxacin HCI and levofloxacin are in a group of antibiotics known as fluoroquinolones.
 

- University of Texas Health Science Center at San Antonio
 

www.uthscsa.edu

 
Subscribe to Respiratory Medicine Newsletter
E-mail Address:

 



Related Respiratory Medicine News

Acute lung injury is prevented by FoxM1 protein
Six-minute walk test predicts mortality rates in patients with pulmonary fibrosis
A dog in home may worsen asthma in children
Cystic fibrosis-related diabetes is due to functional abnormalities in beta cells
COPD patients using beta-agonist inhalers are at risk
Beta-agonists linked with increased number of respiratory deaths -study shows
Beta-agonists more than double death rate in COPD patients
No evidence for inhaled corticosteroids efficacy in cystic fibrosis
Lung function test underused in patients with COPD
Wrinkles clue to risk of progressive lung disease (COPD)


For any corrections of factual information, to contact the editors or to send any medical news or health news press releases, use feedback form

Top of Page

 

© Copyright 2004 onwards by RxPG Medical Solutions Private Limited
Contact Us