XML Feed for RxPG News   Add RxPG News Headlines to My Yahoo!   Javascript Syndication for RxPG News

Research Health World General
 
  Home
 
 Latest Research
 Cancer
 Psychiatry
 Genetics
 Surgery
 Aging
 Ophthalmology
 Gynaecology
 Neurosciences
 Pharmacology
 Cardiology
 Obstetrics
 Infectious Diseases
 Respiratory Medicine
 Pathology
 Endocrinology
 Immunology
 Nephrology
  Dialysis
 Gastroenterology
 Biotechnology
 Radiology
 Dermatology
 Microbiology
 Haematology
 Dental
 ENT
 Environment
 Embryology
 Orthopedics
 Metabolism
 Anaethesia
 Paediatrics
 Public Health
 Urology
 Musculoskeletal
 Clinical Trials
 Physiology
 Biochemistry
 Cytology
 Traumatology
 Rheumatology
 
 Medical News
 Health
 Opinion
 Healthcare
 Professionals
 Launch
 Awards & Prizes
 
 Careers
 Medical
 Nursing
 Dental
 
 Special Topics
 Euthanasia
 Ethics
 Evolution
 Odd Medical News
 Feature
 
 World News
 Tsunami
 Epidemics
 Climate
 Business
Search

Last Updated: Nov 17th, 2006 - 22:35:04

Dialysis Channel
subscribe to Dialysis newsletter

Latest Research : Nephrology : Dialysis

   DISCUSS   |   EMAIL   |   PRINT
Hemodialysis causes antioxidant loss leading to long-term complications
Apr 8, 2005, 01:34, Reviewed by: Dr.

"It is important to prevent reactive oxygen species production by improving the biocompatibility of the hemodialysis system"

 
An article published in Hemodialysis International discusses the role of oxidative stress (OS) in dialysis patients, an imbalance which can result in long-term health problems. Potential therapeutic options to restore balance in patients are also reviewed.

Oxidative stress, an imbalance between toxic compounds and defense mechanisms, and prevalent in the dialysis process, has been linked to numerous adverse complications in end-stage renal disease (ESRD) patients. The imbalance is caused by the overproduction of reactive oxygen species (ROS), or toxic compounds, and lack of antioxidants to fight these toxins. In fact, the hemodialysis process can cause loss of these necessary antioxidants.

Many ESRD and hemodialysis patients are in a state of chronic inflammation induced by the dialysis process which further enhances oxidative stress. This state is strongly associated with long-term complications such as cardiovascular disease, malnutrition, poor outcome and low survival.

"It is important to prevent reactive oxygen species production by improving the biocompatibility of the hemodialysis system," states Dr. Jean-Paul Cristol, corresponding author. Antioxidant supplementation and ROS modulation by specific or non-specific drugs, such as statins, are possible solutions outlined in the article.

"Correction of OS imbalance appears to be a basic requisite to prevent complications in long-term dialysis patients" and is "a promising avenue of research."
 

- This study is published in Hemodialysis International.
 

www.blackwellpublishing.com

 
Subscribe to Dialysis Newsletter
E-mail Address:

 

About the Author
Jean-Paul Cristol, MD is Head of the Biochemistry Department atLapeyronie Universitary Hospital in Montpellier, France. His experience in this field includes characterization of oxidative stress during uremia and hemodialysis, modulation of reactive oxygen species production by statins, and involvement of oxidative stress in atherosclerosis including animal models and clinical studies. Dr. Cristol can be reached for questions and interviews at [email protected]

About Hemodialysis International
Formerly, the journal was published three times a year and contained the Proceedings of the International Symposium on Hemodialysis held in conjunction with the Annual Dialysis Conference. Beginning in 2005, Hemodialysis International is published quarterly and contains original papers on clinical and experimental topics related to Hemodialysis. The Proceedings of the Annual Dialysis Conference are now published as a supplement to HI. Hemodialysis International is a must-have for Nephrologists, Nurses and Technicians worldwide. Quarterly issues of Hemodialysis International are included with the membership to the International Society for Hemodialysis (ISHD). The journal contains original articles, review articles, educational articles, commentary and latest news to keep readers completely updated in the field of hemodialysis. Edited by international and multidisciplinary experts, Hemodialysis International disseminates critical information in the field.

About the International Society for Hemodialysis
The International Society for Hemodialysis is an international and interdisciplinary society of nephrology physicians, critical care physicians, vascular surgeons, renal fellows, nurses, and other health professionals interested in Hemodialysis. Membership of the International Society for Hemodialysis is open to any individual who is interested in the field of hemodialysis. Patients, patients' relatives, technologists, social workers, dietitians, administrators, sales experts, nurses, scientists, journalists, physicians, industrialists, and philanthropists are all welcome. The Society can be joined on their website www.ishd.net.

About Blackwell Publishing
Blackwell Publishing is the world's leading society publisher, partnering with more than 600 academic and professional societies. Blackwell publishes over 750 journals and 600 text and reference books annually, across a wide range of academic, medical, and professional subjects.


Related Dialysis News

Dialysis patients may be overmedicated
Dialysis patients often have close family members also on dialysis - Study
Hemodialysis causes antioxidant loss leading to long-term complications
Oxidative Stress in Dialysis Patients can Lead to Long-Term Health Problems


For any corrections of factual information, to contact the editors or to send any medical news or health news press releases, use feedback form

Top of Page

 

© Copyright 2004 onwards by RxPG Medical Solutions Private Limited
Contact Us