||Last Updated: Nov 17th, 2006 - 22:35:04
Many adults with psychiatric disorders may also have undiagnosed ADHD
Shire plc (LSE: SHP, NASDAQ: SHPGY, TSX: SHQ) announced today that many adults with a depressive disorder, Bipolar Disorder (BPD), or an anxiety disorder may also have undiagnosed Attention-Deficit/Hyperactivity Disorder (ADHD), according to a longitudinal retrospective medical claims analysis presented today at a major medical meeting of child and adolescent psychiatrists.
Oct 28, 2006, 05:38
Lisdexamfetamine dimesylate (NRP104/LDX) is generally well-tolerated.
Shire plc (LSE: SHP, NASDAQ: SHPGY, TSX: SHQ) and its collaborative partner New River Pharmaceuticals Inc. (NASDAQ: NRPH) announced today that their investigational ADHD treatment, lisdexamfetamine dimesylate (also known as NRP104 or LDX), yielded a 60 percent improvement in the primary rating scale scores for symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD) in children aged 6 to 12 years who received six months of treatment in an open-label phase III study. Results also demonstrated that at 6 months, 95 percent of children taking lisdexamfetamine dimesylate (NRP104/LDX) produced a "much improved" or "very much improved" rating on the Clinical Global Impressions – Improvement score. These results were presented last weekend at a national meeting of child and adolescent psychiatrists.
Oct 28, 2006, 05:34
Preschoolers with ADHD improve with low doses of medication
The first long-term, large-scale study designed to determine the safety and effectiveness of treating preschoolers who have attention deficit/hyperactivity disorder (ADHD) with methylphenidate (Ritalin) has found that overall, low doses of this medication are effective and safe. However, the study found that children this age are more sensitive than older children to the medication's side effects and therefore should be closely monitored. The 70-week, six-site study was funded by the National Institutes of Health's National Institute of Mental Health (NIMH) and was described in several articles in the November 2006 issue of the Journal of the American Academy of Child and Adolescent Psychiatry.
Oct 17, 2006, 02:43
Controlling behavior of children with tourette and tic disorders
A program to train parents how to manage the disruptive behavior of children with Tourette syndrome (TS) and tic disorders works well, according to a pilot study conducted by Yale School of Nursing and the Yale Child Study Center.
Sep 27, 2006, 00:19
OROS methylphenidate is best for teenage drivers with ADHD
Researchers at the University of Virginia Health System have found that teenage drivers with attention deficit hyper activity disorder (ADHD) drive better when they took OROS methylphenidate (OROS MPH), a controlled-release stimulant, rather than extended release amphetamine salts (se-AMPH ER).
Sep 6, 2006, 01:05
Almost half of kids with ADHD are not being treated
In contrast to claims that children are being overmedicated for attention-deficit/hyperactivity disorder (ADHD), a team of researchers at Washington University School of Medicine in St. Louis has found that a high percentage of kids with ADHD are not receiving treatment. In fact, almost half of the children who might benefit from ADHD drugs were not getting them.
Aug 7, 2006, 13:49
How ADHD drugs work in brain
Although millions depend on medications such as Ritalin to quell symptoms of attention deficit hyperactivity disorder (ADHD), scientists have struggled to pinpoint how the drugs work in the brain.
Jun 27, 2006, 01:25
Pycnogenol reduces hyperactivity, increases concentration in ADHD
A new study to be published in the June 17 edition of the journal of European Child & Adolescent Psychiatry shows a significant reduction of Attention-Deficit/Hyperactivity Disorder (ADHD) symptoms in children after supplementing with Pycnogenol® (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree, everyday for one month.
Jun 17, 2006, 20:20
Severe body image concerns under-recognized in teens
Adolescents with negative body image concerns are more likely to be depressed, anxious, and suicidal than those without intense dissatisfaction over their appearance, even when compared to adolescents with other psychiatric illnesses, according to a new study by researchers at Bradley Hospital, Butler Hospital and Brown Medical School.
Jun 8, 2006, 06:16
Prematurity and low birth weight increase risk of hyperkinetic disorder
Premature or low birthweight babies are up to three times as likely to become hyperactive, with low attention spans, suggests research published ahead of print in the Archives of Disease in Childhood. Hyperactivity, low attention span, and impulsive behaviour characterise the syndrome known as hyperkinetic disorder, or HKD for short. It is one of the most common mental disorders diagnosed among children, say the authors.
Jun 5, 2006, 16:48
Ritalin, from whiskers to brain
Methylphenidate (Ritalin) elevates norepinephrine levels in the brains of rats to help focus attention while suppressing nerve signal transmissions in the sensory pathways to make it easier to block out extraneous stimuli, a Philadelphia research team has found. Their report in the Journal of Neurophysiology helps explain how a stimulant aids people with attention deficit and hyperactivity disorders to improve their focus without increasing their motor activity. Methylphenidate, prescribed under the brand name Ritalin, has been used for more than 20 years, mostly in children, to treat attention deficit hyperactivity disorder (ADHD) and attention deficit disorder (ADD). The drug can also help people who don't suffer either disorder to attend better to a cognitive task.
May 31, 2006, 17:03
NRP104 significantly reduced symptoms of attention deficit hyperactivity disorder in children
Treatment with the investigational drug, lisdexamfetamine dimesylate (NRP104), demonstrated statistically significant reduction in the symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD) in children aged 6 to 12 years according to the results of a phase III trial presented today at the American Psychiatric Association (APA) annual meeting.
May 25, 2006, 13:20
Extreme personality poses risk of ADHD, conduct disorder
Children with personalities marked by aggressiveness, mood swings, a sense of alienation and a need for excitement may be at greater risk for attention deficit hyperactivity disorder or conduct disorder, according to a new Florida State University study.
Mar 22, 2006, 07:58
Increased cognitive control in Tourette's syndrome
Though the repetitive vocal and motor tics characteristic of Tourette's syndrome may suggest an inability to control involuntary actions at the cognitive level, researchers have now found evidence that young people with Tourette's syndrome actually exhibit a greater level of cognitive control over their movements than their non-affected peers do. The research findings are consistent with a greater need for cognitive control of actions in individuals with Tourette's syndrome, and they offer clues to which regions of the brain may be involved in the generation of the syndrome's characteristic behavioral tics.
Mar 21, 2006, 02:23
TV viewing may not increase chances of ADHD
Children who watch television are no more likely to develop attention disorders, say scientists rejecting earlier studies that linked kids' television exposure to such problems. Earlier studies found that children who watch TV more often could face several health problems such as loss of sleep, poor academic performances and symptoms of attention deficit-hyperactivity disorder (ADHD), a mental condition.
Mar 8, 2006, 04:38
Parental Conflict Produces More Than Fleeting Distress for Children
Six-year-olds whose parents displayed frequent disagreements in their relationship responded to subsequent parental conflicts with elevated distress and negative thoughts, according to a team of researchers from the University of Rochester and the University of Notre Dame.
Feb 12, 2006, 18:36
Teasing contributes to children's eating disorder
Distress over being teased about their weight and rejection by peers could lead to eating disorders in children, says a study.
Feb 12, 2006, 17:58
Methylphenidate transdermal system showed promise
Shire announced at the US Psychiatric and Mental Health Congress in Las Vegas, Nevada, that its investigational methylphenidate transdermal system (MTS) demonstrated statistically significant reductions in the symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD) and was generally well tolerated in patients aged 6 to 12 in two clinical trials.
Nov 12, 2005, 20:24
Antisocial behaviour and ADHD linked to mothers' smoking during pregnancy
Both antisocial behaviour and attention-deficit hyperactivity disorder (ADHD) symptoms in offspring are independently influenced by maternal smoking during pregnancy, a new study has found.
Aug 7, 2005, 14:40
Surprise findings on childhood depression
A child's social environment may have only a modest effect on whether very young children become depressed, according to new Australian research.
Jun 2, 2005, 16:01
ADHD Improves with Sensory Intervention
Preliminary findings from a study of children with attention deficit hyperactivity disorder (ADHD) show that sensory intervention -- for example, deep pressure and strenuous exercise -- can significantly improve problem behaviors such as restlessness, impulsivity and hyperactivity. Of the children receiving occupational therapy, 95 percent improved. This is the first study of this size on sensory intervention for ADHD.
May 13, 2005, 19:59
Medication Combined with Behavior Therapy Works Best for ADHD
A new University at Buffalo study of treatments for children with attention deficit hyperactivity disorder (ADHD) has found that combining behavior modification therapy with medication is the most effective way to improve the behavior of many ADHD children.
May 7, 2005, 18:44