||Last Updated: Nov 17th, 2006 - 22:35:04
New brain-chemistry differences found in depressed women
A new brain study finds major differences between women with serious depression and healthy women in a brain-chemical system that's crucial to stress and emotions.
Nov 7, 2006, 14:26
Stereotypical self-image interferes with depression treatment
A man’s stereotypical self-image as the “strong, silent type” and the stigma of depression are major reasons why older men are less likely than women to be referred to studies of depression, to seek treatment for depression, and to recognize and express symptoms of depression, according to clinicians and recruiters interviewed for a new study from the UC Davis Department of Psychiatry and Behavioral Sciences.
UC Davis Health System is an integrated, academic health system encompassing UC Davis School of Medicine, the 577-bed acute-care hospital and clinical services of UC Davis Medical Center, and the 800-member physician group known as UC Davis Medical Group.
Sep 29, 2006, 16:15
Exaggerated inflammatory response to psychological stress seen in major depression
Individuals with major depression have an exaggerated inflammatory response to psychological stress compared to those who do not suffer from depression, according to a study by researchers at Emory University School of Medicine. Because an overactive inflammatory response may contribute to a number of medical disorders as well as to depression, the findings suggest that increased inflammatory responses to stress in depressed patients may be a link between depression and other diseases, including heart disease, as well as contributing to depression itself.
Sep 4, 2006, 16:03
Ever-happy mice may hold key to new treatment of depression
A new breed of permanently 'cheerful' mouse is providing hope of a new treatment for clinical depression. TREK-1 is a gene that can affect transmission of serotonin in the brain. Serotonin is known to play an important role in mood, sleep and sexuality. By breeding mice with an absence of TREK-1, researchers were able create a depression-resistant strain. The details of this research, which involved an international collaboration with scientists from the University of Nice, France, are published in Nature Neuroscience this week.
Aug 24, 2006, 13:13
Treating depression may raise anxiety levels
An Indo-American team studying the brain of genetically engineered mice has found out why some people under treatment for depression are driven to commit suicide. All antidepressant medications sold in the US are required to carry a warning that use of these drugs 'increased the risk of suicidal thinking and behaviour.' The US Food and Drug Administration (FDA) made this warning mandatory two years ago on the basis of short-term clinical studies in children and adolescents.
Aug 15, 2006, 15:10
Depressed singles receive greater psychological benefits from getting married
Depressed singles receive greater psychological benefits from getting married than those who are not depressed, new research shows. While many studies have shown that marriage helps boost well-being, most studies have looked at a general, average population and don't examine whether some people were helped more by marriage than others.
Aug 14, 2006, 13:51
STAR*D Trial: Third antidepressant medication might help in treatment-resistant depression
The next wave of results from the nation's largest real-world study of treatment-resistant depression shows that patients had a moderate chance of becoming symptom-free when they switched to a third antidepressant medication, following two previously unsuccessful medication attempts. These results from the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial, funded by NIMH, were published in the American Journal of Psychiatry on July 1, 2006.
Jul 10, 2006, 21:01
Residual Depressive Cognitions could Predict Relapse of Depressive Illness
Some individuals with a history of depression may sink back into thinking patterns associated with the condition when faced with mild stresses or sadness, increasing their risk for relapse, according to a report in the July issue of the Archives of General Psychiatry, one of the JAMA/Archives journals. Many patients who recover from depression eventually relapse, according to background information in the article. Management of depression usually focuses on alleviating symptoms rather than reducing the risk for recurrence or identifying patients who might relapse after successful treatment. Previous studies have found that some patients who have recovered from depression still show cognitive processes-patterns in thinking, learning and memory-commonly associated with the condition, while others in remission do not. Such cognitive processes include certain ways of explaining events or particular assumptions about self-worth.
Jul 4, 2006, 13:26
Link Between Depression and Heart Disease
Naturally occurring steroids in the body may make people with a history of depression more vulnerable to coronary heart disease, according to new research from the University of Birmingham.
Jul 4, 2006, 01:43
Social factors not hormones cause post-natal depression
Women are being sold the idea that their bodies are biologically faulty and they need medication for PMS, post-natal depression and menopausal outbursts when in fact the pressures of being 'superwoman' are more likely to blame, says a leading expert.
Jun 22, 2006, 05:11
No evidence for congenital abnormalities by paroxetine
A study carried out by German researchers has failed to show that a popular antidepressant, paroxetine, causes congenital abnormalities if taken by pregnant women, the 22nd annual conference of the European Society of Human Reproduction and Embryology heard today (Monday).
Jun 20, 2006, 00:49
FDA approved Wellbutrin for seasonal affective disorder (SAD)
The Food and Drug Administration (FDA) today approved Wellbutrin XL for prevention of major depressive episodes in patients with a history of seasonal affective disorder (SAD). This is the first drug approved for SAD. Wellbutrin XL (bupropion HCL extended release tablets) previously was approved for treatment of major depressive disorder.
Jun 13, 2006, 05:41
Depression and Diabetes: Which Comes First?
The use of antidepressant drugs was associated with a significantly increased risk of developing type 2 diabetes in people who were already at greater risk of the disease – and this effect was not seen in those taking the drug metformin, according to a report presented here today at the American Diabetes Association's 66th Annual Scientific Sessions. Other studies yielded conflicting reports on the role of depression in the risk for diabetes. Researchers concurred, however, that those who have diabetes and depression need better management for the latter, which can interfere with their ability to provide self care for their diabetes.
Jun 13, 2006, 05:16
Brain images suggest vagal nerve stimulation for severe depression can take months to work
It takes time – between three and 12 months – before a new type of therapy for treatment-resistant depression starts to benefit patients, according to new preliminary brain scan research that confirms earlier observations by psychiatrists about vagal nerve stimulation. Saint Louis University, working in collaboration with Washington University School of Medicine, conducted a pilot study of brain scans of a small group of depressed patients who received vagal nerve stimulation after failing other therapies. Positron emission tomography (PET) scans showed significant changes in brain activity starting three months after vagal nerve stimulation treatment began. These changes continued to evolve over the course of the next 21 months.
May 26, 2006, 13:53
Melatonin improves mood in winter depression
OHSU study reveals how low-dose melatonin taken in the afternoon helps most winter depressives whose physiological clocks are off kilter due to the later winter sunrise
May 7, 2006, 19:41
SSRI anti-depressants may cause stillbirth
Women who take a type of antidepressant medication during pregnancy face the risk of a stillborn baby, warns a study. Canadian researchers at the University of Ottawa compared the health of babies born to 972 women taking SSRI (selective serotonin reuptake inhibitors) with that of babies born to mothers who did not use anti-depressants.
Apr 10, 2006, 13:54
Brain imaging can predict effectiveness of CBT in depression
Whether or not cognitive behavior therapy (CBT) will help a person recover from depression can be predicted through brain imaging, according to research results published by the University of Pittsburgh School of Medicine in the April issue of the American Journal of Psychiatry, the official journal of the American Psychiatric Association.
Apr 3, 2006, 06:52
Successful treatment of mothers with depression helps their children
Children whose mothers are depressed are more likely to suffer from anxiety, mental-health problems and disruptive behavior than those whose moms aren't. And if the mothers don't get better, these kids' problems often become worse, new research shows.
Mar 22, 2006, 07:10
Women with urinary incontinence face depression risk
Women who suffer from urinary incontinence are more likely to be depressed, says a study.
Mar 22, 2006, 01:27
Anti-depressant use associated with increased risk for heart patients
In a surprising finding, patients with coronary artery disease who take commonly used antidepressant drugs may be at significantly higher risk of death, Duke University Medical Center researchers have found. Even after controlling for such factors as age, degree of heart disease and severity of depression, the researchers found that heart patients taking antidepressant medications had a 55 percent higher risk of dying. Previously, Duke researchers reported that the presence of depression is an important risk factor for heart patients. This new finding of the risk from anti-depressants raises issues about the optimal way to treat depression in cardiac patients, the researchers said. According to Duke team leader Lana Watkins, Ph.D., the researchers believe their findings add further support for the potential role oft non-pharmocological approaches to treating depression, such as exercise, in reducing the risk of death in depressed heart patients. She said that physicians caring for heart patients who are taking antidepressants should monitor patients closely.
Mar 6, 2006, 17:24
Brain Derived Neurotrophic Factor (BDNF) plays a role in development of social aversion
A Florida State University scientist used a gene transfer technique to block the expression of a gene associated with clinical depression in a new study of mice that could lead to better treatment of human beings with this condition.
Feb 12, 2006, 18:28
SSRIs linked with increased risk of persistent pulmonary hypertension in newborns
A University of California , San Diego (UCSD) School of Medicine collaborative study with Boston University ’s Slone Epidemiology Center found an increased risk of persistent pulmonary hypertension (PPHN) in newborns of mothers who used certain commonly prescribed antidepressants in late pregnancy. The results of the study will be published in the February 9 issue of the New England Journal of Medicine.
Feb 10, 2006, 15:52
Depression frequent and highly persistent in 'oldest old'
Amongst the oldest old (85-plus), depression is frequent and highly persistent, according to a new study from The Netherlands.
Jan 23, 2006, 17:22
Radio Frequency-powered Neural Stimulator (RFNS) as treatment for depression, seizures
Researchers from the University of Pittsburgh, with the help of a team of Pittsburgh high school science teachers, have developed a wireless device that is implanted in the neck to fight depression and epileptic seizures. The U.S. Food and Drug Administration already has approved a wired version of the device, but that one carries risks and several undesirable side effects.
Jan 21, 2006, 22:04
Antidepressants may affect human immune system
Drugs that treat depression by manipulating the neurotransmitter serotonin in the brain may also affect the user's immune system in ways that are not yet understood, say scientists from Georgetown University Medical Center and a Canadian research institute.
Jan 21, 2006, 21:54
Heritability of major depression is higher in women
Virginia Commonwealth University researchers have found that genes contribute more strongly to the risk of depression in women than in men, and that there may be some genetic factors that are operating uniquely in one sex and not in the other.
Jan 7, 2006, 17:55
Suicide risk decrease after initiation of antidepressants
The risk of serious suicide attempts or death by suicide generally decreases in the weeks after patients start taking antidepressant medication, according to a new study led by Group Health Cooperative researchers and published in the January issue of The American Journal of Psychiatry. The study also found that the risk of suicidal behavior after starting 10 newer antidepressant medications is less than the risk posed by older medications. These findings challenge a 2004 advisory by the U.S. Food and Drug Administration (FDA), which warned that suicidal behavior may emerge after treatment with the newer antidepressant drugs has begun.
Jan 1, 2006, 20:41
Swimming with dolphins can alleviate depression
Swimming with dolphins is an effective treatment for mild to moderate depression, say researchers in this week’s BMJ. Their findings support the theory of biophilia, which shows how human health and wellbeing are dependent on our relationships with the natural environment. The study was carried out in Honduras and involved 30 patients diagnosed with mild or moderate depression. Half were assigned to the experimental group and half to the control group.
Nov 25, 2005, 17:44
Promising Results from CCBT in Depression
Internet-delivered cognitive-behavioural therapy should be pursued further as a complement to treatment, or treatment alternative, for mild to moderate depression, a new study from Sweden has found. It is known that major depression can be treated with cognitive-behavioural therapy, but as skilled therapists are in short supply there is a need for self-help approaches. Many people with depression use the internet for discussion of their symptoms and to share their experiences.
Nov 10, 2005, 19:01
Abortion Does Not Raise Risk Of Depression
Claims that terminating an unwanted first pregnancy raises the risk of depression is called into question in a study published online by the BMJ. In fact, the authors suggest that abortion may be linked to a lower risk of depression through beneficial effects on education, income, and family size. The study involved 1,247 US women who aborted or delivered an unwanted first pregnancy between 1970 and 1992. The women were interviewed over several years to examine the relation between pregnancy outcome and later depression.
Oct 29, 2005, 14:42