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Last Updated: Nov 1, 2009 - 11:48:48 PM |
Latest Research
Progress made on group B streptococcus vaccine
WHAT: Scientists supported by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have completed a Phase II clinical study that indicates a vaccine to prevent Group B Streptococcus (GBS) infection is possible. GBS is the most common cause of sepsis and meningitis in newborns in the United States, according to the Centers for Disease Control and Prevention (CDC). It can also cause severe illness in pregnant women, the elderly and adults with chronic illnesses. Colonization of the genital or gastrointestinal tract is a critical risk factor for infections due to GBS.
Oct 30, 2009 - 3:59:36 AM
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Latest Research
NIH launches 2009 H1N1 influenza vaccine trials in HIV-infected pregnant women
The first clinical trials to test whether the 2009 H1N1 influenza vaccine can safely elicit a protective immune response in pregnant women launched yesterday, and a trial to conduct the same test in HIV-infected children and youth will begin next week. The International Maternal Pediatric Adolescent AIDS Clinical Trials Group is conducting the studies, which are sponsored and funded by the National Institute of Allergy and Infectious Diseases (NIAID) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), both part of the National Institutes of Health.
Oct 9, 2009 - 3:59:36 AM
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Latest Research
NIAID announces vaccine adjuvant discovery contracts
The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has awarded six new research contracts to discover and characterize novel adjuvants, substances that can be added to vaccines to enhance the protective immune response they induce.
Oct 8, 2009 - 3:59:36 AM
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Latest Research
Lessons learned from H1N1 virus pandemic
A comprehensive study has revealed, for the first time, the impact of swine flu on the health of the general public in Australia and New Zealand.
Oct 8, 2009 - 3:59:36 AM
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Latest Research
Research ensures 50 million vaccinated against deadly brain infection
Research at the University of Liverpool has supported the vaccination of more than 50 million people against a zoonotic brain infection that affects thousands of children across Asia every year.
Oct 6, 2009 - 3:59:36 AM
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Latest Research
HIV vaccine regimen demonstrates modest preventive effect in Thailand clinical study
In an encouraging development, an investigational vaccine regimen has been shown to be well-tolerated and to have a modest effect in preventing HIV infection in a clinical trial involving more than 16,000 adult participants in Thailand. Following a final analysis of the trial data, the Surgeon General of the U.S. Army, the trial sponsor, announced today that the prime-boost investigational vaccine regimen was safe and 31 percent effective in preventing HIV infection.
Sep 24, 2009 - 3:59:36 AM
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Latest Research
New vaccine strategy might offer protection against pandemic influenza strains
A novel vaccine strategy using virus-like particles (VLPs) could provide stronger and longer-lasting influenza vaccines with a significantly shorter development and production time than current ones, allowing public health authorities to react more quickly in the event of a potential pandemic.
May 18, 2009 - 3:59:36 AM
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Latest Research
Novel lung cancer vaccine shows promise in fighting early-stage lung cancer
CHICAGO - An experimental vaccine that triggers the patient's immune system to identify and attack specific tumor cells is showing new promise for the treatment of early lung cancer. Thoracic surgeons at Rush University Medical Center are researching the vaccine called MAGE-A3 Antigen-Specific Cancer Immunotherapeutic, which is designed to kill cancer cells without harming normal cells. Rush is one of only five hospitals in Illinois offering the vaccine.
Apr 6, 2009 - 3:59:36 AM
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Latest Research
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Infectious Diseases
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Dengue
New Test to Establish In-Vivo Safety of Dengue Vaccine
Washington, Feb 16 - Researchers have developed a test to determine whether vaccines against a virus that infects 100 million people annually, now ready for clinical trials, should really protect patients from infection, or would make it more dangerous for them.
Feb 16, 2009 - 4:35:46 PM
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Latest Research
Ireland Cancer Center researcher finds most triple-negative breast cancers express muc-1 target
CLEVELAND: Research out of the Ireland Cancer Center of University Hospitals Case Medical Center has found that the vast majority of triple negative breast cancers express the MUC-1 target. This first-of-its-kind finding, presented today at the San Antonio Breast Cancer Symposium, has paved the way for an upcoming vaccine trial for patients with early stage triple negative breast cancer that could potentially prevent recurrence of this aggressive type of breast cancer.
Dec 12, 2008 - 4:59:37 AM
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Latest Research
Immunology Center will continue to drive standard methods, better science
The Rochester Human Immunology Center (RHIC) has been awarded a $4 million renewal of its grant from the National Institute of Allergy and Infection Disease (NIAID). The renewal enables RHIC to continue leading the field of immunology in a worldwide effort to standardize how researchers use complex technologies like flow cytometry that are central to the discovery of new treatments.
Dec 11, 2008 - 4:59:37 AM
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Latest Research
1918 Spanish flu records could hold the key to solving future pandemics
Ninety years after Australian scientists began their race to stop the spread of Spanish flu in Australia, University of Melbourne researchers are hoping records from the 1918 epidemic may hold the key to preventing future deadly pandemic outbreaks.
Nov 9, 2008 - 4:59:37 AM
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Latest Research
Pneumococcal vaccine could prevent numerous deaths, save costs during a flu pandemic, model predicts
A new predictive model shows that vaccinating infants with 7 valent pneumococcal conjugate vaccine (PCV7)--the current recommendation--not only saves lives and money during a normal flu season by preventing related bacterial infections; it also would prevent more than 357,000 deaths during an influenza pandemic, while saving $7 billion in costs.
Oct 28, 2008 - 3:59:37 AM
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Latest Research
Groundbreaking, lifesaving TB vaccine a step closer
Researchers at Aberystwyth University, following a number of years of investment by the Biotechnology and Biological Sciences Research Council (BBSRC), have licensed ground-breaking research to a non-profit product development partnership working to develop new, more effective vaccines against Tuberculosis (TB). This development will give hope that significantly better prevention and treatment of TB will be available within the next few years.
Oct 7, 2008 - 3:59:37 AM
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Latest Research
USU researchers awarded $5.6 million NIH grant to fight deadly viruses
Researchers at the Uniformed Services University of the Health Sciences (USU) have been awarded a $5.6 million grant from the National Institute of Allergy and Infectious Diseases (NIAID) to develop and test vaccines and treatments for the deadly Nipah and Hendra viruses.
Jun 27, 2008 - 3:59:37 AM
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Latest Research
New HIV browser gives researchers access to valuable data from vaccine trials
SANTA CRUZ, CA--A new HIV data browser developed by the University of California, Santa Cruz, and the nonprofit organization Global Solutions for Infectious Diseases (GSID) will give researchers access to a wealth of data collected during clinical trials of an AIDS vaccine. Although the vaccine did not succeed in preventing infections, the clinical trial generated a huge amount of valuable data for researchers studying how the virus evolves and causes new infections.
May 29, 2008 - 3:59:37 AM
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Latest Research
Method for fast human antibodies against flu could find broad use
Scientists have developed a new, faster way to create human monoclonal antibodies against infectious disease by tapping the immune system at the peak of its powers.
Apr 30, 2008 - 3:59:37 AM
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Latest Research
A simplified method of giving rabies vaccine
A simplified economical method of giving rabies vaccine is just as effective as the expensive standard vaccine regimen at stimulating anti-rabies antibodies.
Apr 22, 2008 - 3:59:37 AM
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Latest Research
New vaccine may give long-term defense against deadly bird flu and its variant forms
WEST LAFAYETTE, Ind. - A new vaccine under development may provide protection against highly pathogenic bird flu and its evolving forms, according to researchers at Purdue University and the Centers for Disease Control and Prevention who discovered the new preventative drug and have tested it in mice.
Apr 17, 2008 - 3:59:37 AM
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Latest Research
Vaccine/antibody therapy effective, milder side effects in melanoma and ovarian cancer
BOSTON--One of the shortcomings of a therapy that uses millions of identical antibodies to boost the immune system's attack on cancer cells is that many patients whose tumors recede in response to the treatment also experience serious inflammatory problems, such as severe diarrhea and rashes. In a new study, a team led by Dana-Farber Cancer Institute researchers shows that giving periodic infusions of such monoclonal antibodies to patients who have received a widely used cancer vaccine unleashes a strong immune response to tumors, with less-harsh side effects.
Feb 18, 2008 - 4:59:37 AM
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Latest Research
T cell immunity enhanced by timing of interleukin-7 therapy
MADISON -- That the cell nurturing growth factor interleukin-7 can help ramp up the ability of the immune system to remember the pathogenic villains it encounters is well known.
Feb 5, 2008 - 8:24:37 AM
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Latest Research
Drug aimed at 2 bioterror agents blocks live viral infection, Weill Cornell team reports
NEW YORK (Dec. 19, 2007) -- Two deadly and highly infectious viruses -- both potential bioterror threats -- may have met their match in a new drug developed by scientists at Weill Cornell Medical College in New York City.
Dec 19, 2007 - 4:59:37 AM
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Latest Research
Poxvirus ability to hide from the immune system may aid vaccine design
The cowpox virus, a much milder cousin of the deadly smallpox virus, can keep infected host cells from warning the immune system that they have been compromised, researchers at Washington University School of Medicine in St. Louis have found. The scientists also showed that more virulent poxviruses, such as the strains of monkeypox prevalent in Central Africa, likely have the same ability.
Nov 15, 2007 - 4:59:37 AM
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Latest Research
Mice help researchers understand chlamydia
Genetically engineered mice may hold the key to helping scientists from Queensland University of Technology and Harvard hasten the development of a vaccine to protect adolescent girls against the most common sexually transmitted disease, Chlamydia.
Oct 29, 2007 - 3:59:37 AM
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Latest Research
Influenza: Insights into cell specificity of human vs. avian viruses
Rotterdam, The Netherlands — Researchers have identified which sites and cell types within the respiratory tract are targeted by human versus avian influenza viruses, providing valuable insights into the pathogenesis of these divergent diseases. The report by van Riel et al, “Human and avian influenza viruses target different cells in the lower respiratory tract of humans and other mammals,” appears in the October issue of The American Journal of Pathology and is accompanied by a commentary and highlighted on the cover.
Oct 9, 2007 - 3:59:37 AM
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Latest Research
Patients with pneumonia who received pneumococcal vaccine have lower rate of death, ICU admission
Among patients hospitalized with community-acquired pneumonia, those who had previously received the pneumococcal vaccine had a lower risk of death and admission to the intensive care unit than patients who were not vaccinated, according to a report in the Oct. 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Oct 8, 2007 - 3:59:37 AM
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Latest Research
NIH grant supports UCSF research exploring early HIV infection
A team led by researchers at the UCSF Positive Health Program has been named to receive $15 million over five years to expand understanding of the complex interactions between HIV and the immune systems of newly infected patients following HIV transmission.
Oct 8, 2007 - 3:59:37 AM
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Latest Research
Scripps research scientists develop innovative dual action anthrax vaccine-antitoxin combination
The immune response generated in rats by the new agent protects against lethal toxin exposure after only one injection, and is faster and stronger than any currently available vaccine.
Oct 4, 2007 - 3:59:37 AM
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Latest Research
Flu vaccine in painless skin patches under development at Emory, Georgia Tech with NIH grants
Flu vaccine delivered through painless microneedles in patches applied to the skin could soon be an alternative to delivery through hypodermic needles, according to researchers at Emory University and the Georgia Institute of Technology. Using new grants from the National Institutes of Health (NIH) totaling approximately $11.5 million over five years, researchers from the two institutions plan to develop a new vaccine product using the microscopic needles.
Oct 3, 2007 - 3:59:37 AM
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Latest Research
Second pathway behind HIV-associated immune system dysfunction identified
Researchers at the Partners AIDS Research Center at Massachusetts General Hospital (PARC-MGH) may have discovered a second molecular “switch” responsible for turning off the immune system’s response against HIV. Last year members of the same team identified a molecule called PD-1 that suppresses the activity of HIV-specific CD8 T cells that should destroy virus-infected cells. Now the researchers describe how a regulatory protein called CTLA-4 inhibits the action of HIV-specific CD4 T cells that control the overall response against the virus. The report will appear in the journal Nature Immunology and is receiving early online release.
Sep 30, 2007 - 3:59:37 AM
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Latest Research
Chronic infection persists by targeting stromal cell network in lymphoid organs
One of the biggest challenges to treating infectious diseases and developing preventive vaccines is the ability of many chronic infections to suppress the immune T-cell response over time. An Emory-led team of scientists has discovered one important way in which chronic viral infections are able to evade the immune response. The research is reported this week online in the Proceedings of the National Academy of Sciences.
Sep 18, 2007 - 3:59:37 AM
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Latest Research
New nanoparticle vaccine is more effective but less expensive
Good news for public health: Bioengineering researchers from the EPFL in Lausanne, Switzerland, have developed and patented a nanoparticle that can deliver vaccines more effectively, with fewer side effects, and at a fraction of the cost of current vaccine technologies.
Sep 16, 2007 - 3:59:37 AM
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Latest Research
Novel HIV vaccine created at The Wistar Institute funded for clinical development
(PHILADELPHIA) – A promising new HIV vaccine created at The Wistar Institute has received funding for clinical development aimed at moving the vaccine into human clinical trials as soon as possible.
Aug 31, 2007 - 3:59:37 AM
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Latest Research
Binghamton University researchers investigate evolving malaria resistance
Funded by a $1.5 million grant from the National Institutes of Health, scientists at Binghamton University, State University of New York, hope to understand how the malaria parasite Plasmodium falciparum evolved resistance to the once-effective medication chloroquine.
Aug 30, 2007 - 3:59:37 AM
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Latest Research
IAVI, CDC and USMHRP release new data redefining laboratory reference ranges in Africa
(SEATTLE, August 21, 2007) Leading researchers from the International AIDS Vaccine Initiative (IAVI), the U.S. Centers for Disease Control and Prevention (CDC) and the U.S. Military HIV Research Program (USMHRP) presented final results today from a collection of independent studies reexamining the medical criteria for including African volunteers in AIDS vaccine trials. The findings, presented at the AIDS Vaccine 2007 Conference in Seattle, suggest that many healthy Southern and East Africans have, in the past, been excluded from participating in trials based on laboratory reference ranges that were developed for Western populations and may not be appropriate locally. Implementation of the results of the studies should improve participation of African volunteers in clinical trials for new drugs and vaccines against emerging infectious diseases currently ravaging Africa, including AIDS, TB and malaria, and enable clinicians to better monitor and define adverse events in trials.
Aug 21, 2007 - 3:59:37 AM
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Latest Research
Tumors use enzyme to recruit regulatory T-cells and suppress immune response
One way tumors fly under the radar of the immune system is by using IDO, an enzyme used by fetuses to help avoid rejection, to recruit powerful regulatory T cells that turn down the immune response, researchers say.
Aug 16, 2007 - 3:59:37 AM
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Latest Research
Anthrax vaccine produces immunity with nanoparticles, not needles
ANN ARBOR, Mich. — A vaccine against anthrax that is more effective and easier to administer than the present vaccine has proved highly effective in tests in mice and guinea pigs, report University of Michigan Medical School scientists in the August issue of Infection and Immunity.
Aug 15, 2007 - 3:59:37 AM
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Latest Research
HPV vaccine does not appear to be effective for treating pre-existing HPV infection
For women with human papillomavirus (HPV) infection, use of the HPV-16/18 vaccine will not accelerate reduction of the virus and should not be used to treat the infection, according to a study in the August 15 issue of JAMA.
Aug 14, 2007 - 3:59:37 AM
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Latest Research
DNA vaccine against multiple sclerosis appears safe, potentially beneficial
A newly developed DNA vaccine appears safe and may produce beneficial changes in the brains and immune systems of individuals with multiple sclerosis, according to an article posted online today that will appear in the October 2007 print issue of Archives of Neurology, one of the JAMA/Archives journals.
Aug 13, 2007 - 3:59:37 AM
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Latest Research
Study reveals gaps in vaccine financing for underinsured children
A national survey of state immunization program managers reveals gaps in coverage for the current vaccine financing system, suggesting that many underinsured children may not receive recommended vaccinations, such as for pneumonia and meningitis, according to a report in the August 8 issue of JAMA.
Aug 7, 2007 - 3:59:37 AM
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Latest Research
Study suggests nonpharmaceutical interventions may be helpful in severe influenza outbreaks
An analysis of non-pharmaceutical interventions used in the U.S. during the 1918-1919 influenza pandemic, such as closing schools and banning public gatherings, found an association between these interventions and reduced death rates, suggesting that non-pharmaceutical interventions may play a role in planning for future influenza pandemics, according to a study in the August 8 issue of JAMA.
Aug 7, 2007 - 3:59:37 AM
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Latest Research
Immune mechanism could help explain transient immune suppression often seen in acute infections
Scientists have discovered that at the same time the immune system is vigorously attacking invading viruses or bacteria, it is unexpectedly reducing its production of a particular type of factor that directs the movement of immune cells. The new finding, which could help explain the transient immune suppression often seen during acute infections, shows that the immune system is even more complex than previously believed.
Aug 2, 2007 - 3:59:37 AM
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Latest Research
Phase II study of therapeutic vaccine shows efficacy in patients with metastatic colorectal cancer
PHILADELPHIA – A therapeutic cancer vaccine has shown effectiveness when given alongside chemotherapy to patients with metastatic colorectal cancer in a phase II trial, according to researchers at Oxford BioMedica (UK) Ltd. The study found that six of the 17 metastatic colorectal cancer patients in the study showed tumor shrinkage, classified as complete or partial responses following independent expert review.
Aug 1, 2007 - 3:59:37 AM
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Latest Research
New target for HIV/AIDS drugs and vaccine discovered
Researchers from Rome, Italy, describe a finding in the August 2007 print issue of The FASEB Journal that could lead to new drugs to fight the HIV/AIDS virus, as well as new vaccines to prevent infection. It has been known that HIV proteins disable the antibody-forming part of the immune system (the “homeland defense” or acquired immune system). In this report, researchers demonstrate for the first time how the HIV-1 Nef viral protein delivers a one-two punch to the body’s innate immune system (our “early warning system” composed of dendritic and natural killer cells). First, Nef hijacks dendritic cells (DCs) to upset the function of natural killer (NK) cells. Second, after blocking this first line of defense against the immune system, Nef uses DCs and NK cells to create a microenvironment that actually makes it easier for HIV/AIDS to replicate.
Jul 26, 2007 - 3:59:37 AM
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Latest Research
Measles vaccinations need to be repeated to protect HIV-infected children
HIV-infected children may require repeat measles vaccination for protection, according to new research from the Johns Hopkins Bloomberg School of Public Health and other institutions. The researchers found that only half of the HIV-infected children who survived without antiretroviral therapy maintained protective antibody levels 27 months after receiving measles vaccine. By comparison, 89 percent of children without HIV maintained their immunity, as did 92 percent of the HIV-infected children who were revaccinated in a mass measles immunization campaign during the 27 months of follow-up. The study results were published online June 19, 2007, by The Journal of Infectious Diseases, and will be included in the August 1, 2007, printed issue of the journal.
Jul 17, 2007 - 3:59:37 AM
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Latest Research
Vaccine trials inject hope into koala's future
The first Australian trials of a vaccine developed by Queensland University of Technology that could save Australia's iconic koala from contracting chlamydia are planned to begin later this year.
Jul 16, 2007 - 3:59:37 AM
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Latest Research
Immune system 'escape hatch' gives cancer cells traction
Scientists at Johns Hopkins and elsewhere say they have mapped out an escape route that cancers use to evade the bodyÂ’s immune system, allowing the disease to spread unchecked.
Jul 16, 2007 - 3:59:37 AM
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Latest Research
Japan's DNAVEC and IAVI partner on novel AIDS vaccine strategy
Tsukuba City, Japan and New York, July 9, 2007—The New York-based International AIDS Vaccine Initiative (IAVI) and DNAVEC Corporation today announced a collaboration to jointly develop an AIDS vaccine using DNAVEC's Sendai virus (SeV) vector technology. The candidate will be designed to be administered intra-nasally to stimulate immune responses in both the blood and mucosal tissues, the initial point of entry for HIV.
Jul 9, 2007 - 3:59:37 AM
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Latest Research
Novel genetics research advances possibility of HIV vaccine
A pioneering collaborative study has discovered how the HIV virus evades the human bodyÂ’s immune system.
Jul 5, 2007 - 3:59:37 AM
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Latest Research
Researchers discover method for identifying how cancer evades the immune system
One of the fundamental traits of a tumor – how it avoids the immune system – might become its greatest vulnerability, according to researchers from the University of Southern California. Their findings, demonstrated in human breast and colorectal cancers, indicate that a technique for determining a tumor’s “immune signature,” could be useful for diagnosing and treating specific cancers.
Jul 2, 2007 - 3:59:37 AM
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Musculoskeletal problems ail computer workers
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Eating less may help you live longer
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IOM report on national vaccine plan
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You may damage knees if you're an exercise freak
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American adults receiving flu vaccine at about the same rate as in 2008, study finds
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Widowed people have higher mortality
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Anxious women more likely to have smaller babies
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UIC receives $1 million grant to study 'fat taxes,' diet, obesity
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Progress made on group B streptococcus vaccine
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Exercise addiction could prove fatal
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| | Healthcare |
Biotech industry hails tax sops in Indian budget
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Junior doctors in Madhya Pradesh call off strike
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25000 NRI Doctors Could Return to India from UK
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AIIMS to guide 40 medical colleges on drug reaction
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15 percent of Indian women below 50 are obese: Azad
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Mexico expects swine flu infections to peak at New Year
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Wipro unveils new application for remote healthcare
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Azad hikes funds for cancer control, treatment of poor
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Kerala medical colleges doctors suspend agitation
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Delhi records 280 cases of dengue
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| | Latest Research |
Belatacept may preserve renal function better than calcineurin inhibitors in kidney transplantation
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K-State professor finds link between low oxygen levels in body and cancer-aiding protein
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HHMI's Gilliam Fellowships aim to increase diversity in the sciences
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Saving lives one breath at a time
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Improvements needed in genomic test result discussions
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Occupational sunlight exposure and kidney cancer risk in men
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The life and death of online communities
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Deep sedimentation of acantharian cysts -- a reproductive strategy?
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Adele Boskey 2010 recipient of ORS/AOA award for lifetime contributions to orthopedics
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National Jewish Health receives grant to learn how families cope with food allergy
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| | Medical News |
Azad invites NRI investment in pharmaceuticals, medical education
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25000 NRI Doctors Could Return to India from UK
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Eat pistachio to lower blood sugar
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Stricter resident doctor duty hour required to prevent medical errors
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Chandigarh adult drinks 11 bottles a month
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Swine flu vaccine nearing development: Official
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India to be diabetes' world capital by 2025: Expert
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US may allow 5,000 more Indian doctors for residency training
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Scissors taken out from man's stomach after two years
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India's swine flu toll reaches 967, over 26,000 infected
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| | Special Topics |
'Primodial Soup' theory for origin of life rejected in paper
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Human species could have killed Neanderthal man
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History, geography also seem to shape our genome
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3,000 Kerala medical students to attend inter-college meet
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Tamil Nadu seeks to control deemed universities
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Spiders which eat together, stay together and multiply
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Anna Hazare - the keeper of the earth and human conscience
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Indian American scientist wins top IMO prize
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Artificial human sperm could make men redundant: experts
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Will autopsy on Benazir's body become necessary?
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