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Latest Research : Pharmacology
  Last Updated: Mar 10, 2009 - 10:52:28 PM

Latest Research : Pharmacology
Majority of family nurse practitioners have low awareness of influence of marketing by pharmaceutical companies
Family nurse practitioners need to be more aware of the commercial pressures they face as a result of their increased involvement in prescribing, according to a survey published in the March issue of the UK-based Journal of Advanced Nursing.
Mar 10, 2009 - 10:47:24 PM

Latest Research : Pharmacology
Mode of activity of recombinant human activated protein C (rhAPC) discovered
Researchers have found a way to block the ability of white blood cells to sprint toward the sites of infection when such speed worsens the damage done by sepsis, the often fatal, whole-body bacterial infection, according to a study published in the journal Blood. The results recommend existing drugs as potential new treatments against sepsis, and suggest improvements in the current treatment that would increase its effect while eliminating a treatment-related risk for internal bleeding.
Feb 25, 2009 - 12:53:53 AM

Latest Research
New surgical option for wrist arthritis
NEW YORK (Feb. 13, 2009) -- Breaking a fall, such as a tumble on the sidewalk, with your hands and wrists is everyone's natural reflex. But, if you fall hard enough, you'll often fracture your radius bone, or even one of the smaller wrist bones and wrist ligaments. Left untreated, these injuries could lead to disabling wrist arthritis.
Feb 13, 2009 - 5:00:00 AM

Latest Research
Unexplained chest pain can be due to stress
Each year, many people seek emergency treatment for unexplained chest pains. A thesis from the Sahlgrenska Academy, University of Gothenburg, Sweden, indicates several common factors among those affected, including stress at work, anxiety, depression and a sedentary lifestyle.
Feb 9, 2009 - 5:00:00 AM

Latest Research : Pharmacology : Antihypertensives
ACE 2- Potential treatment for hypertension
Huijing Xia, PhD, a postdoctoral research associate in the lab of Eric Lazartigues, PhD, Assistant Professor of Pharmacology at LSU Health Sciences Center New Orleans, is the lead author on a paper reporting that a recently identified enzyme in the brain plays a critically important role in the central regulation of blood pressure. The LSUHSC research team showed that Angiotensin-converting enzyme 2 (ACE2) helps preserve the function of a key spontaneous reflex involved in blood pressure regulation and confirms its potential as a target for the prevention or treatment of High Blood Pressure.
Jan 30, 2009 - 2:48:00 PM

Latest Research : Pharmacology : Antibiotics
Inhibition of protein HipA pevents cell dormancy and bacterial persistence
Bacteria survive antibiotic attack when a protein flips a chemical switch that throws them into a dormant state until treatment abates, researchers at The University of Texas M. D. Anderson Cancer Center report in the Jan.16 edition of Science.
Jan 15, 2009 - 2:32:01 PM

Latest Research : Pharmacology : Antibiotics
Study on spread of antibiotic resistance between bacteria
Scientists have identified the structure of a key component of the bacteria behind such diseases as whooping cough, peptic stomach ulcers and Legionnaires' disease. The research, funded by the Wellcome Trust and the Biotechnology and Biological Sciences Research Council (BBSRC), sheds light on how antibiotic resistance genes spread from one bacterium to another.
Jan 10, 2009 - 9:25:41 AM

Latest Research
Genes for 9 health indicators
A new genome-wide study examines genetic variants associated with nine metabolic traits and is the first to draw out novel variants from a population unselected for current disease. The traits are indicators for common disease such as cardiovascular disease, type 2 diabetes, blood pressure, inflammation and lipid levels.
Dec 7, 2008 - 5:00:00 AM

Latest Research
Delays in radiation therapy lead to increased breast cancer recurrence
A new analysis of the National Cancer Institute's cancer registry has found that as many as one in five older women experience delayed or incomplete radiation treatment following breast-conserving surgery, and that this suboptimal care can lead to worse outcomes.
Dec 1, 2008 - 5:00:00 AM

Latest Research : Pharmacology
New method can detect contaminants in life-saving drug
Washington, Nov 18 - A simple, inexpensive method for detecting contaminants in heparin has been devised by Michigan University researchers.

Nov 19, 2008 - 3:54:27 PM

Latest Research
Novel IBS treatment developed at UB garners $8.5 million for seven-year clinical trial
BUFFALO, N.Y. -- Irritable bowel syndrome is a chronic, debilitating disorder affecting 25 million people in the U.S -- 14-24 percent of women and 5-19 percent of men.
Nov 13, 2008 - 5:00:00 AM

Latest Research
FSU researcher's discovery leads to $1.5 million grant, potential new treatment of liver fibrosis
TALLAHASSEE, Fla. -- The discovery of a protein involved in the life-threatening mechanism of liver fibrosis has helped a researcher at the Florida State University College of Medicine attract a $1.5 million grant from the National Institutes of Health.
Oct 17, 2008 - 4:00:00 AM

Latest Research : Pharmacology
'Light' cigarettes occupy most brain nicotine receptors
For decades now, cigarette makers have marketed so-called light cigarettes — which contain less nicotine than regular smokes — with the implication that they are less harmful to smokers' health. A new UCLA study shows, however, that they deliver nearly as much nicotine to the brain.
Sep 26, 2008 - 11:34:51 PM

Latest Research
$4.8M NIH grant aids interstitial cystitis research
University of Iowa researchers are ready to find the causes of interstitial cystitis, thanks to a five-year, $4.8 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health. The grant is the largest ever received by the University of Iowa Department of Urology.
Sep 26, 2008 - 4:00:00 AM

Latest Research : Pharmacology
Triclocarban and triclosan- more risk than benefit?
A new study by UC Davis researchers calls into question the widespread use of two active ingredients -- triclocarban and triclosan -- in personal hygiene products, including anti-bacterial bar and liquid soaps. Using human and animal cell lines, researchers found that triclocarban disrupts reproductive hormone activity and triclosan interferes a type of cell signaling that occurs in brain, heart and other cells.
Jul 12, 2008 - 1:39:41 AM

Latest Research
Statins can provide some protection against dementia
Cholesterol-lowering drugs known as statins have a profound effect on an elite group of cells important to brain health as we age, scientists at the University of Rochester Medical Center have found. The new findings shed light on a long-debated potential role for statins in the area of dementia.

Jul 3, 2008 - 4:00:00 AM

Latest Research
Princeton University survey finds 'pain gap'
A novel study that attempts to paint the most accurate and detailed description yet of how Americans experience pain has found that a significant portion of the population -- 28 percent -- are in pain at any given moment and those with less education and lower income spend more of their time in pain. Those in pain are less likely to work or socialize with others and are more inclined to watch television than the pain-free.
May 1, 2008 - 4:00:00 AM

Latest Research
U. Iowa study finds biological link between pain and fatigue
A recent University of Iowa study reveals a biological link between pain and fatigue and may help explain why more women than men are diagnosed with chronic pain and fatigue conditions like fibromyalgia and chronic fatigue syndrome.
Apr 7, 2008 - 4:00:00 AM

Latest Research
Study: highly involved patients don't always see better health outcomes
Patients who prefer to be highly involved in their treatment don't necessarily have better luck managing chronic health conditions, a new study suggests.
Feb 22, 2008 - 5:00:00 AM

Latest Research
Intensive blood sugar treatment in trial of diabetes and cardiovascular disease changed
The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health has stopped one treatment within a large, ongoing North American clinical trial of diabetes and cardiovascular disease 18 months early due to safety concerns after review of available data, although the study will continue.

Feb 6, 2008 - 11:40:00 PM

Latest Research
Chronic pain harms the brain
CHICAGO -- People with unrelenting pain don't only suffer from the non-stop sensation of throbbing pain. They also have trouble sleeping, are often depressed, anxious and even have difficulty making simple decisions.
Feb 5, 2008 - 5:00:00 AM

Latest Research : Pharmacology : Anti-Clotting Drugs
Direct Intraclot Injection of Alteplase - effective treatment for deep vein thrombosis
A novel treatment for blood clots in the legs appears to be safe and effective, according to a pilot study published in the February issue of Radiology. The study found that injecting or “lacing” the clot with a fiber-binding thrombolytic agent effectively treats deep vein thrombosis (DVT) and reduces the risk of subsequent recurrence or bleeding.
Jan 29, 2008 - 1:26:04 PM

Latest Research
Naked mole-rats bear chili pepper heat
Pity the tiny naked mole-rat. The buck-toothed, sausage-like rodent lives by the hundreds in packed, oxygen-starved burrows some six feet under ground. It is even cold-blooded -- which, as far as we know, is unique among mammals.
Jan 28, 2008 - 5:00:00 AM

Latest Research
Use of opioids for pain in ERs on the rise, but racial differences in use still exist
In the last 15 years, use of opioid medications to treat patients with pain-related emergency department visits has improved although white patients were more likely to receive opioids than patients of a different race/ethnicity, according to a study in the January 2 issue of JAMA.
Jan 1, 2008 - 5:00:00 AM

Latest Research
Constipation most common cause of children's abdominal pain
A new study led by a University of Iowa researcher showed that acute and chronic constipation together accounted for nearly half of all cases of acute abdominal pain in children treated at one hospital.
Dec 17, 2007 - 5:00:00 AM

Latest Research
Study shows pine bark naturally reduces osteoarthritis knee pain

Dec 5, 2007 - 5:00:00 AM

Latest Research
Smoked cannabis proven effective in treating neuropathic pain
Smoked cannabis eased pain induced in healthy volunteers, according to a study by researchers at the University of California, San Diego (UCSD) Center for Medical Cannabis Research (CMCR.) However, the researchers found that less may be more.
Oct 24, 2007 - 4:00:00 AM

Latest Research
Role of a key enzyme in reducing heart disease identified
Virginia Commonwealth University researchers have identified the role of a key enzyme called CEH in reducing heart disease, paving the way for new target therapies to reduce plaques in the arteries and perhaps in the future, help predict a patients susceptibility to heart disease.
Oct 24, 2007 - 4:00:00 AM

Latest Research
Watching funny shows helps children tolerate pain longer, study finds
Watching comedy shows helps children tolerate pain for longer periods of time, according to a study by UCLA's Jonsson Comprehensive Cancer Center and the nonprofit organization Rx Laughter.
Oct 23, 2007 - 4:00:00 AM

Latest Research
Acupuncture reduces pain, need for opioids after surgery
DURHAM, N.C. Using acupuncture before and during surgery significantly reduces the level of pain and the amount of potent painkillers needed by patients after the surgery is over, according to Duke University Medical Center anesthesiologists who combined data from 15 small randomized acupuncture clinical trials.
Oct 16, 2007 - 4:00:00 AM

Latest Research
UI researchers seek to ease children's pain during medical procedures
A new system under development by a team of researchers at the University of Iowa will help children better cope with pain during difficult medical procedures.
Oct 15, 2007 - 4:00:00 AM

Latest Research
Virtual game helps children escape realities of burn unit
COLUMBUS, Ohio -- Nurses and physicians at Nationwide Childrens Hospital are using the latest technology to help young burn victims endure the extreme pain of dressing changes and wound care. Instead of traditional distraction devices, such as books and music, Nationwide Childrens Hospital Burn Center is now using virtual reality games to distract patients while nurses attend to the patients burn wounds.
Oct 8, 2007 - 4:00:00 AM

Latest Research
Cholesterol metabolism links early- and late-onset Alzheimer's disease
Oct. 4, 2007 -- Although the causes of Alzheimer's disease are not completely understood, amyloid-beta (A-beta) is widely considered a likely culprit the sticky protein clumps into plaques thought to harm brain cells.
Oct 4, 2007 - 4:00:00 AM

Latest Research
Treatment blocks pain without disrupting other functions
A combination of two drugs can selectively block pain-sensing neurons in rats without impairing movement or other sensations such as touch, according to a new study by National Institutes of Health (NIH)-supported investigators. The finding suggests an improved way to treat pain from childbirth and surgical procedures. It may also lead to new treatments to help the millions of Americans who suffer from chronic pain.
Oct 3, 2007 - 4:00:00 AM

Latest Research
Women with severe PMS perceive their sleep quality to be poor
WESTCHESTER, Ill. Women with severe premenstrual syndrome (PMS) perceive their sleep quality to be poorer in association with their symptoms in the late luteal (premenstrual) phase, despite there being no specific alterations in sleep structure associated with premenstrual symptoms, according to a study published in the October 1 issue of the journal SLEEP.
Oct 1, 2007 - 4:00:00 AM

Latest Research
Low maternal cholesterol tied to premature birth
Pregnant women who have very low cholesterol may face a greater risk of delivering their babies prematurely than women with more moderate cholesterol levels, a team led by the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), reported today.
Oct 1, 2007 - 4:00:00 AM

Latest Research
New test could help consumers avoid surprise headaches from chocolate, wine
Researchers in California are reporting development of a fast, inexpensive test suitable for home use that could help millions of people avoid those out of the blue headaches that may follow consumption of certain red wines, cheese, chocolate, and other aged or fermented foods.
Oct 1, 2007 - 4:00:00 AM

Latest Research
ACP and APS issue comprehensive guidelines for treating low-back pain
PHILADELPHIA, Oct. 2, 2007 - The American College of Physicians (ACP) and the American Pain Society (APS) today released joint guidelines on diagnosing and treating low back pain.
Oct 1, 2007 - 4:00:00 AM

Latest Research
Treating obstructive sleep apnea, preventing heart attacks and strokes
Researchers in Brazil have found that treating patients who suffer from obstructive sleep apnea (OSA) with continuous positive airway pressure (CPAP) dramatically reduces early indications of atherosclerosis in just months, linking OSA directly to the hardening or narrowing of the arteries. Until now, no study has demonstrated such a direct relationship between the two.
Sep 28, 2007 - 4:00:00 AM

Latest Research
'Bad carbs' not the enemy, University of Virginia professor finds
The latest common wisdom on carbohydrates claims that eating so-called bad carbohydrates will make you fat, but University of Virginia professor Glenn Gaesser says, thats just nonsense. Eating sandwiches with white bread, or an occasional doughnut, isn't going to kill you, or necessarily even lead to obesity, he said.
Sep 28, 2007 - 4:00:00 AM

Latest Research
Doctors learn to control their own brains' pain responses to better treat patients
Physicians apparently learn to shut off the portion of their brain that helps them appreciate the pain their patients experience while treating them and instead activate a portion of the brain connected with controlling emotions, according to new research using brain scans at the University of Chicago.
Sep 27, 2007 - 4:00:00 AM

Latest Research
Why don't painkillers work for people with fibromyalgia?
ANN ARBOR, Mich. People who have the common chronic pain condition fibromyalgia often report that they dont respond to the types of medication that relieve other peoples pain. New research from the University of Michigan Health System helps to explain why that might be: Patients with fibromyalgia were found to have reduced binding ability of a type of receptor in the brain that is the target of opioid painkiller drugs such as morphine.
Sep 27, 2007 - 4:00:00 AM

Latest Research
Mixing large doses of both acetaminophen painkiller and caffeine may increase risk of liver damage
WASHINGTON, Sept. 26 2007 -- Consuming large amounts of caffeine while taking acetaminophen, one of the most widely used painkillers in the United States, could potentially cause liver damage, according to a preliminary laboratory study reported in the Oct. 15 print issue of ACS Chemical Research in Toxicology, a monthly journal. The toxic interaction could occur not only from drinking caffeinated beverages while taking the painkiller but also from using large amounts of medications that intentionally combine caffeine and acetaminophen for the treatment of migraine headaches, menstrual discomfort and other conditions, the researchers say.
Sep 26, 2007 - 4:00:00 AM

Latest Research
Common abdominal pain may be due to a potentially treatable newly recognized inflammatory reaction
JACKSONVILLE, Fla. -- As many as one in four people in westernized countries experience pain or discomfort in their upper abdomen, and physicians have almost nothing to offer except anti-acid medicines, which usually dont work. Now, in a small but novel study, researchers have found evidence that an abnormal amount of inflammatory cells populates the upper intestine of affected individuals, which suggests a fresh way of understanding the common complaint.
Sep 19, 2007 - 4:00:00 AM

Latest Research
Smaller breast reduction surgeries provide health benefits and should be reimbursed
NEW YORK (Sept. 13, 2007) -- Smaller-framed women reap significant health and quality-of-life benefits from breast reductions that involve the removal of under 500 grams of tissue per breast, according to a first-of-its-kind study from NewYork-Presbyterian Hospital/Weill Cornell Medical Center and the New York University School of Medicine.
Sep 13, 2007 - 4:00:00 AM

Latest Research
Preventing or reducing enlarged heart decreases risk of heart failure
NEW YORK (Sept. 10, 2007) -- For high-blood-pressure patients, preventing or reducing enlarged heart (left ventricular hypertrophy or LVH) reduces risk of heart failure. The study is published in the Sept. 4 Annals of Internal Medicine and led by physician-scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center in New York City.
Sep 12, 2007 - 4:00:00 AM

Latest Research
Depression in women with migraine linked to childhood abuse
ST. PAUL, Minn. Childhood abuse is more common in women with migraine who suffer depression than in women with migraine alone, according to a study published in the September 4, 2007, issue of Neurology, the medical journal of the American Academy of Neurology.
Sep 3, 2007 - 4:00:00 AM

Latest Research
Metabolic study in mice could lead to 'good cholesterol' boosters
Researchers have identified a new player in the control of so-called “good” cholesterol that circulates in the bloodstream and reduces heart attack risk, according to a report in the August issue of Cell Metabolism, a publication of Cell Press. Should the metabolic pathway uncovered in mice operate similarly in humans, the new discovery could point the way to therapies that protect against heart disease by boosting concentrations of the beneficial high-density lipoprotein cholesterol (HDL-C).
Aug 7, 2007 - 4:00:00 AM

Latest Research
Older is better -- Top-10 comparison of diabetes drugs give metformin top grade
A type 2 diabetes drug taken orally and in widespread use for more than a decade has been found to have distinct advantages over nine other, mostly newer medications used to control the chronic disease, according to a study by researchers at Johns Hopkins.
Jul 24, 2007 - 4:00:00 AM

Latest Research
Restless legs genetics on the move
In Germany alone 8 million patients are affected by RLS, which makes it one of the most common neurological diseases. The patients suffer from an urge to move and paresthesia in the legs in the evening and during the night, when they come to rest, which can only be relieved by moving or walking around. The consequence may be severe sleeping disorders, chronic sleep loss and – associated with it – daytime fatigue. In severe cases the disease may lead to depression and social isolation. The frequency of RLS increases with age: up to ten per cent of over 65 year olds are affected, albeit in very different forms. Children can, however, also contract the disease.
Jul 19, 2007 - 4:00:00 AM

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