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Latest Research : Genetics
  Last Updated: Nov 2, 2013 - 11:52:55 AM

Health : Public Health
Genetic study of bedbugs may help identify pesticide resistance genes
OhioState University entomologists have conducted the first genetic study of bedbugs, paving the road to the identification of potential genes associated with pesticide resistance and possible new control methods for the troublesome insect, whose sudden resurgence in the United States has led to a public health scare.

Jan 19, 2011 - 5:08:01 PM

Latest Research : Genetics
Novel method of database analysis to help identify responsible genes and diagnostic markers
Researchers at the University of Gothenburg, Sweden, have developed new methods for analysing medical databases that can be used to identify diagnostic markers more quickly and to personalise medication for allergic disorders.
Jan 11, 2011 - 5:53:27 PM

Latest Research : Genetics
Environmental influences can be passed down to the next generation
Scientists at the University of Massachusetts Medical School and the University of Texas at Austin have uncovered evidence that environmental influences experienced by a father can be passed down to the next generation, "reprogramming" how genes function in offspring.
Dec 28, 2010 - 9:48:13 AM

Latest Research : Genetics
Gene found to be key in etiology of cleft palate
Cleft palate has been linked to dozens of genes. During their investigation of one of these genes, researchers at Washington University School of Medicine in St. Louis were surprised to find that cleft palate occurs both when the gene is more active and when it is less active than normal.
Feb 2, 2010 - 1:54:58 PM

Latest Research : Genetics
History, geography also seem to shape our genome
History and geography shape our genome, according to a new study.

Jun 18, 2009 - 6:00:21 PM

Latest Research : Genetics
Induced pluripotent stem cell lines from pigs
The discovery that adult skin cells can be 'reprogrammed' to behave like stem cells has been a major scientific boon, providing a way to tap the potential of embryonic stem cells without the associated ethical quandaries. Now, in a study appearing online in JBC, researchers have created a line of such reprogrammed stem cells from adult pigs.
Jun 7, 2009 - 3:44:15 AM

Latest Research : Genetics
Egg cells help extend life of sperms
In contrast to women, men are fertile throughout life, but research at the Sahlgrenska Academy, University of Gothenburg, Sweden, has now shown that a fertilising sperm can get help from the egg to rejuvenate. The result is an important step towards future stem cell therapy.
Mar 25, 2009 - 3:59:20 PM

Latest Research : Genetics
Family of genes known as KRAB-ZFP regulate genes dealing with stress
Research conducted by a team in Switzerland suggests that a family of genes involved in regulating the expression of other genes in the brain is responsible for helping us deal with external inputs such as stress. Their results, appearing in the December 11 advance online version of the journal Neuron, may also give a clue to why some people are more susceptible to anxiety or depression than others.
Dec 12, 2008 - 1:33:47 PM

Latest Research : Genetics
New screening strategy increases Down's syndrome detection before birth
A new national screening strategy in Denmark has halved the number of infants born with Down's syndrome and increased the number of infants diagnosed before birth by 30%, according to a study published on bmj.com.
Nov 29, 2008 - 3:34:26 AM

Latest Research : Genetics
Can genetic research spur racist attitudes?
Toronto, Nov 18 - People might be different in many ways but genetically they are quite similar. However, is it possible that genetic research may evoke racist attitudes, asks University of Alberta's Tim Caulfield. He organised a seminar to examine the issue.

Nov 19, 2008 - 11:59:33 AM

Latest Research : Genetics
Atlas of kidney genome created
A comprehensive genome-based atlas, created by researchers, would help shed light on healthy and abnormal kidney development and disease. The atlas shows how the entire genome is regulated to produce thousands of specific genes that are mixed and re-mixed to form genetic teams.

Nov 13, 2008 - 10:43:26 AM

Latest Research : Genetics
Customised DNA-based prescriptions to avert drug reactions
Washington, Oct 24 - Customised DNA-based prescriptions could help avert adverse drug reactions, a new research has found.

Oct 24, 2008 - 4:42:27 PM

Latest Research : Genetics : Genetic Disorders
XXYY syndrome- features and treatment options elucidated by researchers
Researchers at the UC Davis M.I.N.D. Institute and The Children's Hospital in Denver have conducted the largest study to date describing the medical and psychological characteristics of a rare genetic disorder in which males have two "X" and two "Y" chromosomes, rather than the normal one of each. The study, published in the June 15, 2008, issue of the American Journal of Medical Genetics Part A, also offers treatment recommendations for men and boys with the disorder.
Aug 24, 2008 - 1:16:40 AM

Latest Research : Genetics
UC Davis M.I.N.D institute to start screening for fragile X
Researchers at the UC Davis M.I.N.D. Institute will launch the first widespread newborn screening for the genetic mutation that results in fragile X syndrome, the single most common inherited cause of mental retardation.
Aug 19, 2008 - 11:49:03 PM

Latest Research : Genetics
A tall story? Genes do manipulate height
New York, April 7 - Scientists now have a far clearer picture of what makes some people tall - and others not so.

Apr 7, 2008 - 9:41:15 AM

Latest Research : Genetics
Large gap between Genomic Medicine and Clinical practice
A large gap exists between what knowledge is available about genomic medicine and incorporating it into clinical practice for assessing the risk of and treating common chronic diseases, such as cardiovascular disease, diabetes mellitus, and cancer, according to a systematic review in the March 19 issue of JAMA, a theme issue on Genetics and Genomics.
Mar 18, 2008 - 9:31:45 AM

Latest Research
Moving an active gene from the interior of the nucleus can silence genes , preventing their transcription . scientists report .
Moving an active gene from the interior of the nucleus to its periphery can inactivate that gene report scientists from the University of Chicago Medical Center .
Feb 14, 2008 - 4:00:00 AM

Latest Research
Europe's most common genetic disease is a liver disorder
Much less widely known than the dangerous consequences of iron deficiencies is the fact that too much iron can also cause problems. The exact origin of the genetic iron overload disorder hereditary hemochromatosis (HH) has remained elusive. In a joint effort, researchers from the European Molecular Biology Laboratory (EMBL) and the University of Heidelberg, Germany, have now discovered that HH is a liver disease. They report in the current issue of Cell Metabolism that the disorder develops when a crucial gene is lacking in liver cells.

Feb 6, 2008 - 8:55:00 PM

Latest Research : Psychiatry : Depression
Genetic variations may predispose some men to suicidal thoughts during treatment for depression
Genetic variations may help explain why some men with depression develop suicidal thoughts and behaviors after they begin taking antidepressant medications, while most do not, according to a report in the June issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
Jun 7, 2007 - 4:00:00 PM

Latest Research : Genetics : Genetic Disorders
Switching genes to overdrive improves muscular dystrophy symptoms in mice
Scientists at Dana-Farber Cancer Institute have shown in a laboratory study that revving up a crucial set of muscle genes counteracts the damage caused by a form of muscular dystrophy.
Apr 1, 2007 - 11:56:50 AM

Latest Research : Genetics : Genetic Disorders
Gene mutation associated with X-linked mental retardation revealed
Researchers have identified a novel gene mutation that causes X-linked mental retardation for which there was no previously known molecular diagnosis, according to an article to be published electronically on Tuesday, March 20, 2007 in The American Journal of Human Genetics.
Mar 19, 2007 - 10:53:10 PM

Latest Research : Genetics
RNA Silencing Sheds Light on the RNA World
RNA silencing — also known as RNA interference — is an intriguing phenomenon in which short, double-stranded RNA “triggers” can prevent the expression of specific genes. First discovered in plants, RNA interference is now recognized as a widespread, if not ubiquitous, phenomenon, and it is causing great excitement as an experimental technique for selectively blocking gene expression.
Dec 5, 2006 - 7:51:55 AM

Latest Research : Genetics : Genetic Disorders : Huntington's
Link between Huntington's and abnormal cholesterol levels in brain discovered
Mayo Clinic researchers have discovered a protein interaction that may explain how the deadly Huntington's disease affects the brain. The findings, published in and featured on the cover of the current issue of Human Molecular Genetics, show how the mutated Huntington's protein interacts with another protein to cause dramatic accumulation of cholesterol in the brain.
Dec 3, 2006 - 3:10:30 PM

Latest Research : Genetics
Reinventing Human genome
Geneticists have generally assumed that your string of DNA 'letters' is 99.9% identical to that of your neighbour's, with differences in the odd individual letter. These differences make each person genetically unique — influencing everything from appearance and personality to susceptibility to disease. But hold on, say the authors of a new study published in Nature. They have identified surprisingly large chunks of the genome that can differ dramatically from one person to the next.
Nov 23, 2006 - 4:27:05 PM

Latest Research : Genetics
Wnt reactivates dormant limb regeneration program
Chop off a salamander's leg and a brand new one will sprout in no time. But most animals have lost the ability to replace missing limbs. Now, a research team at the Salk Institute for Biological Studies has been able to regenerate a wing in a chick embryo – a species not known to be able to regrow limbs - suggesting that the potential for such regeneration exists innately in all vertebrates, including humans.
Nov 18, 2006 - 1:52:57 PM

Latest Research : Genetics
New research into csd genes could help designing strategies for breeding honey bees
Three years ago, scientists pinpointed a gene called csd that determines gender in honey bees, and now a research team led by University of Michigan evolutionary biologist Jianzhi "George" Zhang has unraveled details of how the gene evolved.
Oct 27, 2006 - 4:46:00 PM

Latest Research : Genetics : Genetic Disorders
Williams Syndrome, the brain and music
Children with Williams syndrome, a rare genetic disorder, just love music and will spend hours listening to or making music. Despite averaging an IQ score of 60, many possess a great memory for songs, an uncanny sense of rhythm, and the kind of auditory acuity, than can discern differences between different vacuum cleaner brands.
Oct 5, 2006 - 12:58:00 AM

Latest Research : Genetics
Genetic mutation identified as cause of cranio-lenticulo-sutural dysplasia
A research team led by a UC Davis Children’s Hospital scientist has identified a genetic mutation as the cause of a congenital craniofacial birth defect called cranio-lenticulo-sutural dysplasia. The mutation closes off a pathway that is vital to the transport of cellular proteins and, in doing so, significantly alters normal growth patterns of skeletal and connective tissue. The research finding, which appears in the October issue of Nature Genetics , is independently confirmed in a Vanderbilt University Medical Center study published in the same issue
Sep 29, 2006 - 4:08:00 PM

Latest Research : Genetics
Chance Fluctuations in mRNA Output in Mammalian Cells
In the drama of cell biology, both genetics and environment write the script, and chance throws in the twists of plot. In general, most cells live relatively predictable lives: divide, differentiate, and die. Yet chance leaves its imprint even in ordinary cells. For instance, bacterial or yeast cells in culture are known to produce widely different amounts of certain proteins, even when they are genetically identical. Scientists attribute such cell-to-cell variations to chance fluctuations in the cells’ ability to make these proteins. They also speculate that such fluctuations may benefit the cells in their struggle to adapt and survive.
Sep 13, 2006 - 3:44:00 AM

Latest Research : Genetics
Transposon Silencing Keeps Jumping Genes in Their Place
Nearly a century ago, two geneticists described “rogue” pea plants with an unorthodox pattern of inheritance. William Bateson and Caroline Pellew found that crossing inferior rogues with normal plants always produced rogue offspring, suggesting that the rogue appearance was a dominant trait. The real surprise came when rogue progeny were crossed back to normal plants. Following the principles of Mendelian inheritance, these crosses should have produced a mix of normal and rogue plants, but they produced only rogue plants. The phenomenon, later dubbed “paramutation,” allowed the rogues to break the rules by acting “epigenetically”—inducing heritable changes in gene expression without DNA mutations. In one-sided interactions between gene pairs, or alleles, only “paramutagenic” alleles can attenuate, and eventually silence, the expression of “paramutable” alleles.
Sep 13, 2006 - 3:40:00 AM

Latest Research : Genetics
GATA2 - predicting susceptibility to coronary artery disease
Variations in a gene that acts as a switch to turn
on other genes may predispose individuals to heart disease, an international team of researchers led by Duke University Medical Center scientists has discovered.

Aug 26, 2006 - 2:15:00 AM

Latest Research : Genetics : Genetic Disorders
Exploring genetics of congenital malformations
New research published in the August issue of the Journal of Cell Biology explains for the first time why congenital heart defects so often occur with limb deformities. In their research into the molecular mechanisms that control embryonic limb and heart development, Northwestern University researcher Hans-Georg Simon and his laboratory group recently identified a new protein, LMP4, which binds and regulates activity of the Tbx4 and Tbx5 transcription factors. Tbx5 and Tbx4 proteins play a key role in limb and heart formation in virtually all vertebrates, from fish to birds to mice to humans.
Aug 19, 2006 - 9:42:00 PM

Latest Research : Genetics
Genome insertions and deletions (INDELs) provide expanded view of human genetic differences
Emory University scientists have identified and created a map of more than 400,000 insertions and deletions (INDELs) in the human genome that signal a little-explored type of genetic difference among individuals. INDELS are an alternative form of natural genetic variation that differs from the much-studied single nucleotide polymorphisms (SNPs). Both types of variation are likely to have a major impact on humans, including their health and susceptibility to disease.
Aug 11, 2006 - 2:19:00 PM

Latest Research : Genetics
BRIT1 gene identified as protector of DNA
A single gene plays a pivotal role launching two DNA damage detection and repair pathways in the human genome, suggesting that it functions as a previously unidentified tumor suppressor gene, researchers at The University of Texas M. D. Anderson Cancer Center report in Cancer Cell.
Aug 6, 2006 - 11:17:00 AM

Latest Research : Genetics : Genetic Disorders
FDA Approves Idursulfase As First Treatment for Hunter Syndrome
The Food and Drug Administration (FDA) approved Elaprase (idursulfase), the first product for the treatment of Hunter syndrome (Mucopolysaccharidosis II, or MPS II), a rare inherited disease which can lead to premature death. Elaprase is a new molecular entity, which is an active ingredient never before marketed in the United States.
Aug 2, 2006 - 12:30:00 PM

Latest Research : Genetics : Genetic Disorders : Huntington's
PARP1 inhibitors can protect Huntington's disease affected cells from damage
An enzyme known to be critical for the repair of damaged cells and the maintenance of cellular energy may be a useful target for new strategies to treat Huntington's disease (HD) and other disorders characterized by low cellular energy levels. In the August issue of Chemistry & Biology, a research team from the MassGeneral Institute for Neurodegenerative Disease (MIND) describes their discovery of a novel inhibitor of Poly (ADP-ribose) polymerase (PARP1) and their findings that PARP1 inhibitors can protect HD-affected cells from damage in laboratory assays.
Jul 30, 2006 - 2:41:00 AM

Latest Research : Genetics
Genetic Gender Gap in Disease Risk, Drug Response
UCLA researchers report that thousands of genes behave differently in the same organs of males and females – something never detected to this degree. Published in the August issue of Genome Research, the study sheds light on why the same disease often strikes males and females differently, and why the genders may respond differently to the same drug.
Jul 10, 2006 - 6:29:00 AM

Latest Research : Genetics
'Molecular assassin' targets disease gene
University of New South Wales (UNSW) researchers have announced they are developing a new class of experimental drug that has the potential to treat a diverse range of health problems, from inflammation and cancer through to eye and heart disease.
Jul 5, 2006 - 3:16:00 PM

Latest Research : Genetics
Scientists Uncover Rules for Gene Amplification
Gene amplification plays an important role in causing cancers via activation of oncogenes. If scientists can determine the rules as to which segments of genetic material become amplified and how, oncologists and drug researchers may be able to interrupt that process and prevent the formation and growth of some tumors. Using yeast as a model organism, researchers at the Georgia Institute of Technology have discovered that the location of a hairpin-capped break relative to the end of the chromosome will determine the fate of the amplification event.
Jun 30, 2006 - 1:17:00 PM

Latest Research : Genetics : Genetic Disorders : Huntington's
Gene therapy protects neurons in Huntington's disease
Researchers at Rush University Medical Center, Chicago, and Ceregene Inc., San Diego, have successfully used gene therapy to preserve motor function and stop the anatomic, cellular changes that occur in the brains of mice with Huntington's disease (HD). This is the first study to demonstrate that, using this delivery method, symptom onset might be prevented in HD mice with this treatment.
Jun 30, 2006 - 3:02:00 AM

Latest Research : Genetics
DNA damage resets the cellular circadian clock
Dartmouth Medical School geneticists have discovered that DNA damage resets the cellular circadian clock, suggesting links among circadian timing, the cycle of cell division, and the propensity for cancer. Their work, reported June 29 in Science Express, the advance electronic publication of Science, implies a protective dimension for the biological clock in addition to its pacemaker functions that play such a sweeping role in the rhythms and activities of life.
Jun 30, 2006 - 2:42:00 AM

Latest Research : Genetics
Human cells use complex system of transcription-factor combinations
Scientists eager to help develop a new generation of pharmaceuticals are studying cellular proteins called transcription factors, which bind to upstream sequences of genes to turn the expression of those genes on or off. Some pharmaceutical companies are also hoping to develop drugs that selectively block the binding of transcription factors as a way to short-circuit the harmful effects of diseases, and researchers at the University of California, San Diego on June 16 reported new findings that could aid that effort.
Jun 19, 2006 - 1:22:00 AM

Latest Research : Genetics : Genetic Disorders : Huntington's
Huntingtin cleavage is caused by caspase-6
Researchers at the University of British Columbia's Centre for Molecular Medicine and Therapeutics (CMMT) have provided ground-breaking evidence for a cure for Huntington disease in a mouse offering hope that this disease can be relieved in humans.
Jun 17, 2006 - 8:10:00 PM

Latest Research : Genetics : Genetic Disorders
The risk of transmission of genetic disorders through donor's sperm
As medical technology continues to advance, fertility procedures such as in-vitro fertilization and donor insemination are becoming more commonplace. However, a study in the May issue of The Journal of Pediatrics warns that, even after thorough screenings of sperm donors, genetic disorders can be transmitted to the conceived children.

May 19, 2006 - 7:25:00 PM

Latest Research : Genetics
How can DNA be damaged
Researchers have known for years that damaged DNA can lead to human diseases such as cancer, but how damage occurs--and what causes it--has remained less clear.
May 18, 2006 - 2:58:00 AM

Latest Research : Genetics
Could cellular defenses against sunlight be the key to effective gene therapy?
An early study has demonstrated for the first time that laser light can target gene therapy right up to the edge of damaged cartilage, while leaving nearby healthy tissue untouched, according to an article published in the April edition of the Journal of Bone and Joint Surgery. True repair of injuries to articular cartilage would enable millions of patients, currently consigned to worsening arthritis and joint replacement, to return to athletic exercise.
Apr 25, 2006 - 7:33:00 PM

Latest Research : Genetics : Genetic Disorders : MSUD
Liver transplants provide metabolic cure for maple syrup urine disease
Liver transplants cured the metabolic symptoms of 11 patients with a rare but devastating genetic condition known as Maple Syrup Urine Disease (MSUD), according to a study by researchers from Children's Hospital of Pittsburgh and the Clinic for Special Children.
Apr 11, 2006 - 10:28:00 PM

Latest Research : Genetics
Gene therapy helps two Germans in global first
For the first time, gene therapy has been used to alter the cells of sick adults and allow them greater resistance to bacteria and fungi, a Germany-based team of scientists said.
Apr 3, 2006 - 2:38:00 PM

Latest Research : Genetics
Mutations Change the Boolean Logic of Gene Regulation
It is easy to think of a gene acting like a light bulb, switching either on or off, remaining silent, or being transcribed by the RNA-making machinery. The region of DNA that controls the gene's output is called its regulatory region, and in this simple (and too simplistic) scenario, that region would act like a simple on–off switch.
Mar 29, 2006 - 6:39:00 AM

Latest Research : Genetics
Synthetic biology experiment turns up a previously unrecognized gene-expression phenomenon
An experiment designed to show how a usually innocuous bacterium regulates the expression of an unnecessary gene for green color has turned up a previously unrecognized phenomenon that could partially explain a feature of bacterial pathogenicity.
Feb 16, 2006 - 7:47:00 PM

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