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Latest Research : Musculoskeletal
  Last Updated: Nov 1, 2009 - 11:48:48 PM

Latest Research
Drug could provide first treatment for scleroderma
Investigators have identified a drug that is currently approved to treat certain types of cancer, Gleevec, that could provide the first treatment for scleroderma, a chronic connective tissue disease for which a treatment has remained elusive. The news will be presented at the annual meeting of the American College of Rheumatology on October 18 in Philadelphia.
Oct 17, 2009 - 3:59:36 AM

Latest Research
Advances in treating hip pain to be focus of International Society for Hip Arthroscopy meeting
Recent advances in diagnostic imaging techniques and hip arthroscopy procedures are giving physicians and surgeons better tools with which to treat hip pain. The 2009 International Society for Hip Arthroscopy meeting, hosted by Hospital for Special Surgery in New York, brings together leading surgeons from all over the world to take an in-depth look at hip arthroscopy and its potential benefits.
Sep 26, 2009 - 3:59:36 AM

Latest Research : Musculoskeletal
Artificial gravity prevents muscle loss in space
When the Apollo 11 crew got back from the moon some 40 years ago, they showed no ill effects from a week spent in weightlessness. But as space men began conducting longer-duration space flights, scientists noticed a disturbing trend: the longer humans stay in zero gravity, the more muscle they lose.
Aug 6, 2009 - 1:30:51 PM

Latest Research
Study to assess hip exercises as treatment for osteoarthritis in the knee joints
Researchers at Rush University Medical Center are testing a novel regimen of hip-muscle exercises to decrease the load on the knee joints in patients with osteoarthritis. The goal is not only to relieve pain but also, possibly, to halt progression of the disease.
Jul 15, 2009 - 3:59:36 AM

Latest Research
Study to assess hip exercises as treatment for osteoarthritis in the knee joints
Researchers at Rush University Medical Center are testing a novel regimen of hip-muscle exercises to decrease the load on the knee joints in patients with osteoarthritis. The goal is not only to relieve pain but also, possibly, to halt progression of the disease.
Jul 15, 2009 - 3:59:36 AM

Latest Research
Surgery may not be necessary for Achilles tendon rupture
The two ends of a ruptured Achilles tendon are often stitched together before the leg is put in plaster, in order to reduce the risk of the tendon rupturing again. However, Katarina Nilsson Helander, MD, PhD at the Sahlgrenska Academy, University of Gothenburg, Sweden, now suggests that surgery may be unnecessary. Patients who do not undergo surgery have just as good a chance of recovery.
May 14, 2009 - 3:59:36 AM

Latest Research
Risk of vibration-induced vascular injuries linked to vibration frequency differences
Speaking on April 19 at the Experimental Biology 2009 meeting in New Orleans, Dr. Kristine Krajnak, a team leader in the Engineering and Control Technologies Branch of the Health Effects Laboratory Division of NIOSH in Morgantown, West Virginia, describes results from the first study to directly link the different physical responses of tissue that occur with exposure to different vibration frequencies with biological mechanisms underlying the development of vascular dysfunction. Her presentation is part of the scientific program of The American Physiological Society.
Apr 19, 2009 - 3:59:36 AM

Latest Research
Biomedical engineering student recognized as IEEE's 'New Face of Engineering'
WASHINGTON (17 March 2009) -- Guruprasad Madhavan is working on neuromuscular stimulation approaches that may help prevent osteoporosis, heart failure and mild cognitive impairment -- all related to low blood pressure.
Mar 17, 2009 - 3:59:36 AM

Latest Research : Musculoskeletal
A couple of glasses of red wine a day keep disabilities away!
It is well known that moderate drinking can have positive health benefits — for instance, a couple of glasses of red wine a day can be good for the heart. But if you're a senior in good health, light to moderate consumption of alcohol may also help prevent the development of physical disability.
Jan 15, 2009 - 2:47:27 PM

Latest Research : Musculoskeletal : Muscular Dystrophies
Sarcospan may help in Duchenne muscular dystrophy
The overlooked and undervalued protein, sarcospan, just got its moment in the spotlight. Peter et al. now show that adding it to muscle cells might ameliorate the most severe form of muscular dystrophy.
Nov 3, 2008 - 12:00:46 AM

Latest Research
'Wildcat Power Cord' repairs cruciate ligament in dairy cow's knee
MANHATTAN, KAN. -- An 8-year-old Jersey dairy cow is back at her Kansas farm thanks to a decade of research and an experimental surgery performed at Kansas State University's Veterinary Medical Teaching Hospital.
Mar 27, 2008 - 3:59:37 AM

Latest Research
Lithium chloride slows onset of skeletal muscle disorder
Irvine, Calif., March 18, 2008 -- A new UC Irvine study finds that lithium chloride, a drug used to treat bipolar disorder, can slow the development of inclusion body myositis, a skeletal muscle disease that affects the elderly.
Mar 18, 2008 - 3:59:37 AM

Latest Research
Massive microRNA scan uncovers leads to treating muscle degeneration
Researchers have discovered the first microRNAs – tiny bits of code that regulate gene activity – linked to each of 10 major degenerative muscular disorders, opening doors to new treatments and a better biological understanding of these debilitating, poorly understood, often untreatable diseases. The study, to be published online this week by the Proceedings of the National Academy of Sciences, was led by Iris Eisenberg, PhD, of the Program in Genomics at Children’s Hospital Boston. Louis Kunkel, PhD, director of the Program in Genomics and an investigator with the Howard Hughes Medical Institute, was senior investigator.
Oct 17, 2007 - 3:59:37 AM

Latest Research
FDA approves knee-injury device for humans
COLUMBIA, Mo. – A new knee-surgery device investigated by University of Missouri-Columbia researchers that will help to repair meniscus tears, which were previously defined as irreparable, has been approved by the FDA for use in humans.
Oct 2, 2007 - 3:59:37 AM

Latest Research : Neurosciences
Brain abnormalities found in people with writer's cramp
People with serious cases of writer�s cramp have brain abnormalities, according to a study published in the July 24, 2007, issue of Neurology, the medical journal of the American Academy of Neurology. People with writer�s cramp had less brain tissue than healthy people in three areas of the brain that connect the senses and movement with their affected hand.
Jul 23, 2007 - 3:59:37 AM

Latest Research
Sports hernia repair technique coupled with innovative rehabilitation program speeds return to play
CALGARY, Alberta -- Surgical repair of athletic hernia using tension-free mesh and a standardized rehabilitation protocol are successful in returning athletes to competition, according to new research released today at the 2007 Annual Meeting of the American Orthopaedic Society for Sports Medicine at the Telus Convention Center (July 12-15).
Jul 15, 2007 - 3:59:37 AM

Latest Research
Sports hernia repair surgery plus innovative rehab program helps athletes return to play
St. Louis, July 15, 2007 — In recent years, sports hernias have sidelined many high-level athletes for months and, occasionally, prevented a return to competitive sports all together. New research at Washington University School of Medicine in St. Louis shows that surgical repair of sports hernias using tension-free mesh, coupled with an innovative rehabilitation program, successfully returned athletes to competition in 93 percent of cases.
Jul 15, 2007 - 3:59:37 AM

Latest Research
Tennis elbow procedure demonstrates long-term success
CALGARY, Alberta -- Arthroscopic treatment of tennis elbow has shown to be successful at long-term follow-up, according to new research released today at the 2007 Annual Meeting of the American Orthopaedic Society for Sports Medicine at the Telus Convention Center (July 12-15).
Jul 14, 2007 - 3:59:37 AM

Latest Research
Women and arthritis sufferers have poorer short-term recovery from arthroscopic knee surgery
CALGARY, Alberta -- The factors associated with poor short-term recovery from knee surgery appear to be different than those found to mar long-term outcome from the same surgery, according to new research released today at the 2007 Annual Meeting of the American Orthopaedic Society for Sports Medicine at the Telus Convention Center (July 12-15).
Jul 14, 2007 - 3:59:37 AM

Latest Research
Serica scientists win AOSSM Award for ACL tissue regeneration in preclinical study
MEDFORD, MA and CALGARY, CANADA, JULY13, 2007 -- Serica Technologies, Inc., a growth-stage medical device company developing silk-based biomaterial platforms for tissue regeneration, today announced that its scientists received the Cabaud Memorial Award from the American Orthopedic Society for Sports Medicine (AOSSM), for their pre-clinical research demonstrating the potential of Serica’s SeriACL™ Graft to regenerate or re-grow anterior cruciate ligament (ACL) tissue in the knee, in a large-animal model.
Jul 13, 2007 - 3:59:37 AM

Latest Research
Groin injuries averted by preseason injury prevention
CALGARY, Alberta -- Professional soccer players who participated in a special preseason groin injury prevention program had fewer groin injuries during that subsequent season than those who were not in the program, according to new research released today at the 2007 Annual Meeting of the American Orthopaedic Society for Sports Medicine at the Telus Convention Center (July 12-15).
Jul 12, 2007 - 3:59:37 AM

Latest Research
Neoprene sleeve equal to knee brace during recovery from ACL surgery
CALGARY, Alberta -- Users of functional knee braces and neoprene sleeves have similar recoveries from anterior cruciate ligament (ACL) reconstruction, according to new research presented today at the 2007 Annual Meeting of the American Orthopaedic Society for Sports Medicine at the Telus Convention Center (July 12-15).
Jul 12, 2007 - 3:59:37 AM

Latest Research
Penn researchers find a new target for muscular dystrophy drug therapy
PHILADELPHIA - Researchers at the University of Pennsylvania School of Medicine report how the gene for utrophin, which codes for a protein very similar to dystrophin, the defective protein in Duchenne muscular dystrophy (DMD), puts the brakes on its own expression in muscle cells, thereby suggesting a new target for treatment. The findings were published online in Molecular Biology Cell, in advance of print publication.
Jul 12, 2007 - 3:59:37 AM

Latest Research
Anti-malarial drug may reduce risk of diabetes for patients with rheumatoid arthritis
Preliminary research suggests that use of the anti-malarial drug hydroxychloroquine may help reduce the risk of the development of diabetes in patients with rheumatoid arthritis, according to a study in the July 11 issue of JAMA.
Jul 10, 2007 - 3:59:37 AM

Latest Research
More muscle for the argument to give up smoking
Researchers at The University of Nottingham have got more bad news for smokers. Not only does it cause cancer, heart attacks and strokes but smokers will also lose more muscle mass in old age than a non-smoker. The effect of this predisposes smokers to an accelerated decline in physical function and loss of independence.
Jul 9, 2007 - 3:59:37 AM

Latest Research
Faulty cell membrane repair causes heart disease
During vigorous exercise, heart muscle cells take a beating. In fact, some of those cells rupture, and if not for a repair process capable of resealing cell membranes, those cells would die and cause heart damage (cardiomyopathy).
Jul 3, 2007 - 3:59:37 AM

Latest Research
New dynamic brace developed to advance clubfoot treatment
A new brace that maintains correction for clubfoot, a birth defect in which the foot is turned in toward the body, has shown better compliance and fewer complications than the traditional brace used to treat the condition.
Jun 28, 2007 - 3:59:37 AM

Latest Research
New genetic test developed at Emory advances detection and diagnosis of muscular dystrophy
A new genetic test targeting the most common types of muscular dystrophy--those caused by mutations in the dystrophin gene--is far quicker with greater accuracy and sensitivity than existing tests. It can be used to confirm clinical diagnoses, to test female family members who may be carriers, and to perform prenatal testing.
Jun 27, 2007 - 3:59:37 AM

Latest Research
Mouse model points to possible new strategy for treating rare muscle disease, kidney disorders
Based on clues provided by a study with transgenic mice, a research group at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), has developed a strategy that will be tested as the first treatment for people with hereditary inclusion body myopathy (HIBM), a rare, degenerative muscle disease. In an unexpected finding, the research indicates that the approach also might benefit patients with certain kidney disorders.
Jun 1, 2007 - 3:59:37 AM

Latest Research
When the villain becomes your friend: The strange tale of muscle lactate
In a paper published this week in The Journal of Physiology, Frank de Paoli and colleagues, working at the University of Aarhus in Denmark, add to the growing literature leading to a more complete understanding of the physiological role of lactic acid production in muscle.
May 31, 2007 - 3:59:37 AM

Latest Research
Existence of muscle-building stem cells points to regenerative therapies for muscular disease
A new report in the June 1 issue of the journal Cell, a publication of Cell Press, confirms the existence of some apparently uncommitted stem cells amongst cells responsible for generating the bulging biceps of body builders and the rippling abs of fitness buffs. The findings could lead to new muscle-regenerating therapies—including cell transplantation regimens and stem cell-replenishing drugs—for people with various muscle-wasting diseases, including muscular dystrophies. Ultimately, such treatments might also help keep people strong as they age, according to the researchers.
May 31, 2007 - 3:59:37 AM

Latest Research
Research shows aerobic exercise helps maintain muscle in elderly
GALVESTON, Texas — Why do older people tend to lose muscle mass and grow frail? One important factor identified by medical science is the reduced ability of the elderly to respond to the muscle-building stimulus of the hormone insulin.
May 30, 2007 - 3:59:37 AM

Latest Research
Biofeedback on abnormal mechanics lowers risk for stress fractures, pain under kneecap
More than seven out of 10 runners will sustain an injury over the course of a year, many of these injuries preventable without any adverse effects on running distance or performance, according to Dr. Irene Davis, director of the Running Injury Lab at the University of Delaware, and director of Research for Drayer Physical Therapy Institute.
Apr 30, 2007 - 3:59:37 AM

Latest Research
Free weight training gets workers with rotator cuff injuries back on the job
Resistance training, some of it job-specific, was successful in getting 90 percent of workers with severe rotator cuff injuries back to work, the majority (75 percent) at their previous job, after traditional physical therapy had failed to do so. Furthermore, all but one of the 42 employees in the study (98 percent) reported satisfaction with the resistance-training program and its outcome.
Apr 29, 2007 - 3:59:37 AM

Latest Research
Green tea compound suppresses factors causing cartilage, bone destruction in arthritis
In rheumatoid arthritis, a person's own immune system attacks the joints by activating the synovial tissue that lines the body's movable joints, causing inflammation, swelling, pain and eventually erosion of the bone and cartilage and deformation of the joint. It is among the most debilitating forms of arthritis, often making difficult even the simplest of daily activities.
Apr 29, 2007 - 3:59:37 AM

Latest Research
Measuring calcium intake can help to identify osteoporosis in men with prostate cancer
Measuring a manÂ’s daily calcium intake is an effective way of identifying prostate cancer patients with a higher than average risk of osteoporosis, according to the April issue of the urology journal BJU International.
Apr 10, 2007 - 3:59:37 AM

Latest Research
The sturdier sex? -- Study by Pittsburgh scientists finds female stem cells work better
PITTSBURGH – April 4, 2007 -- Female stem cells derived from muscle have a greater ability to regenerate skeletal muscle tissue than male cells, according to a study at Children’s Hospital of Pittsburgh of UPMC.
Apr 9, 2007 - 3:59:37 AM

Latest Research
Stevens and Connecticut Innovations agree to investment of $500,000 in SPOC Inc.
HOBOKEN, N.J. -- Stevens Institute of Technology and Connecticut Innovations (CI), the state’s quasi-public authority responsible for technology investing and innovation development, today announced that they had completed an agreement for a seed-stage investment of $500,000 in Stevens Proof of Concept Inc. (SPOC), a Technogenesis® Company founded at Stevens Institute of Technology. CI made this investment through its Connecticut BioSeed Fund.
Apr 2, 2007 - 3:59:37 AM

Latest Research
Switching genes to overdrive improves muscular dystrophy symptoms in mice
BOSTON -- Scientists at Dana-Farber Cancer Institute have shown in a laboratory study that revving up a crucial set of muscle genes counteracts the damage caused by a form of muscular dystrophy.
Mar 31, 2007 - 3:59:37 AM

Latest Research
Women need expanded musculoskeletal care during pregnancy, study finds
(Arlington, Va.) -- Despite the high prevalence of musculoskeletal pain during pregnancy, few women in underserved populations receive treatment for their low back pain, according to a February 2007 study in the Journal of Manipulative and Physiological Therapeutics (JMPT). Moreover, researchers found that pain in a previous pregnancy may predict a high risk for musculoskeletal complaints in future pregnancies.
Mar 6, 2007 - 4:59:37 AM

Latest Research
Modified ligament surgery improves outcomes for baseball pitchers, other athletes
In the largest study of its kind, surgeons at Hospital for Special Surgery have determined that by modifying a classic ligament surgery, they can return more athletes, such as baseball players, to their prior level of competition. The modified surgery repairs a torn medial collateral ligament (MCL), which links and stabilizes bones of the lower and upper arm where they meet at the elbow.
Feb 28, 2007 - 4:59:37 AM

Latest Research
Power-boosting signal in muscle declines with age
As people age, they may have to exercise even harder to get the benefits afforded to younger folk. That's the suggestion of a report in the February issue of the journal Cell Metabolism, published by Cell Press, showing that a signal that gives muscles a kind of metabolic boost in response to exercise is blunted in older animals.
Feb 6, 2007 - 4:59:37 AM

Latest Research
Common blood pressure drug reduces progressive muscle degeneration in mice
Scientists supported in part by the National Institutes of Health's National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and National Institute of Neurological Disorders and Stroke (NINDS) have found that that the commonly prescribed blood pressure medication losartan improves muscle regeneration and repair in a mouse model of Duchenne muscular dystrophy (DMD), a devastating disease characterized by rapid progression of muscle degeneration in boys and young men. The research is based on similarities in the mechanism of DMD and another rare disease — Marfan syndrome — and the discovery that losartan is effective in blocking the key mechanism in animal models of both diseases. Further studies of the drug, scientists emphasize, are needed to assess its value in patients.
Feb 2, 2007 - 4:59:37 AM

Latest Research
Smoking worsens knee osteoarthritis
ROCHESTER, Minn. -- New findings from a study led by a Mayo Clinic rheumatologist indicate that men with knee osteoarthritis who smoke experience greater cartilage loss and more severe pain than men who do not smoke. Results will be published online this week in the Annals of the Rheumatic Diseases.
Dec 7, 2006 - 4:59:37 AM

Latest Research
Improperly sized tennis racket grip doesn't cause tennis elbow
Rosemont, Ill. – December 1, 2006 – Researchers apparently have gotten a grip on the relationship between the development of tennis elbow (tendonitis) and the size of the grip on the racket a player uses.
Dec 1, 2006 - 4:59:37 AM

Latest Research
Helping muscle regenerate
Muscle wasting can occur at all ages as the result of genetic defects, heart failure, spinal injury or cancer. A therapy to cure the loss of muscle mass and strength, which has a severe impact on patients' lives, is desperately sought. Blocking a central signal molecule, researchers from the Mouse Biology Unit of the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy, have now found a way to protect muscle from degenerating after injury and to improve muscle healing in mice. The study appears in the current issue of the Journal of Clinical Investigation and suggests two molecules with the potential to speed up the regeneration of damaged muscle as promising drug targets for new therapies against muscle wasting.
Nov 1, 2006 - 4:59:37 AM

Latest Research : Musculoskeletal : Muscular Dystrophies
Trichostatin A (TSA) Can Counteract Muscular Dystrophy in Mice
Scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other institutions have demonstrated for the first time that a single drug can rebuild damaged muscle in two strains of mice that develop diseases comparable to two human forms of muscular dystrophy. This advance, which is reported online in Nature Medicine, is the latest from a research collaboration that began several years ago by the teams of Vittorio Sartorelli, M.D., at NIAMS and Pier Lorenzo Puri, M.D., Ph.D., now at Dulbecco Telethon Institute (DTI) in Rome, Italy and The Burnham Institute in La Jolla, Calif.
Oct 5, 2006 - 1:07:37 AM

Latest Research
Scientists show drug can counteract muscular dystrophy in mice
Scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other institutions have demonstrated for the first time that a single drug can rebuild damaged muscle in two strains of mice that develop diseases comparable to two human forms of muscular dystrophy. This advance, which is reported online in Nature Medicine, is the latest from a research collaboration that began several years ago by the teams of Vittorio Sartorelli, M.D., at NIAMS and Pier Lorenzo Puri, M.D., Ph.D., now at Dulbecco Telethon Institute (DTI) in Rome, Italy and The Burnham Institute in La Jolla, Calif.
Oct 4, 2006 - 3:59:37 AM

Latest Research
Muscle cells self-destruct rather than grow with use
Muscle cells that should grow stronger with use instead self-destruct when a protein called BAG3 isn't around, researchers have shown.
Aug 30, 2006 - 3:59:37 AM

Latest Research
Women show 47 percent greater persistence with osteoporosis drugs if offered monthly tablet, support
Women who took an osteoporosis drug once a month and received extra telephone support from trained nurses showed 47 per cent greater persistence with their drug treatment than those who took a weekly tablet, according to a study in the August issue of IJCP, the International Journal of Clinical Practice.
Jul 20, 2006 - 3:59:37 AM

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