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Last Updated: May 10, 2008 - 3:38:29 AM |
Latest Research
Suspected cause of type 1 diabetes caught 'red-handed' for the first time
May 8, 2008 -- Scientists at Washington University School of Medicine in St. Louis working with diabetic mice have examined in unprecedented detail the immune cells long thought to be responsible for type 1 diabetes.
May 9, 2008 - 4:00:00 AM
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Latest Research
Method for fast human antibodies against flu could find broad use
Scientists have developed a new, faster way to create human monoclonal antibodies against infectious disease by tapping the immune system at the peak of its powers.
Apr 30, 2008 - 4:00:00 AM
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Latest Research
Specialized white blood cells coordinate first responders to viral infection
Just as fire engines arrive quickly at the scene to save people and property, the cells that fight viruses have to reach the site of an infection promptly to mount a protective response.
Apr 24, 2008 - 4:00:00 AM
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Latest Research
A simplified method of giving rabies vaccine
A simplified economical method of giving rabies vaccine is just as effective as the expensive standard vaccine regimen at stimulating anti-rabies antibodies.
Apr 22, 2008 - 4:00:00 AM
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Latest Research
New vaccine may give long-term defense against deadly bird flu and its variant forms
WEST LAFAYETTE, Ind. - A new vaccine under development may provide protection against highly pathogenic bird flu and its evolving forms, according to researchers at Purdue University and the Centers for Disease Control and Prevention who discovered the new preventative drug and have tested it in mice.
Apr 17, 2008 - 4:00:00 AM
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Latest Research
Blood pressure enzyme can have tumor-sensing role
By increasing production of a blood pressure-regulating enzyme in mice, researchers have found they can enhance the mouse immune system's ability to sense tumor growth.
Apr 7, 2008 - 4:00:00 AM
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Latest Research
Researchers uncover new genetic links to psoriasis
In the first comprehensive study of the genetic basis of psoriasis, researchers at Washington University School of Medicine in St. Louis have discovered seven new sites of common DNA variation that increase the risk of the troublesome skin condition. They also found that variations in one genetic region link psoriasis and a related joint disorder, psoriatic arthritis, to four autoimmune diseases: type 1 diabetes, Grave's disease, celiac disease and rheumatoid arthritis.
Apr 3, 2008 - 4:00:00 AM
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Latest Research
Findings reveal how dengue virus matures, becomes infectious
WEST LAFAYETTE, Ind. - Biologists at Purdue University have determined why dengue virus particles undergo structural changes as they mature in host cells and how the changes are critical for enabling the virus to infect new host cells.
Mar 27, 2008 - 4:00:00 AM
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Latest Research
UT-ORNL and UCSD researchers find promise in HIV 'switch'
KNOXVILLE -- If the battle against HIV, the virus that causes AIDS, is a chess match, then new research published today gives new insight into one of the virus' most important moves.
Mar 16, 2008 - 4:00:00 AM
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Latest Research
How do infections and toxins launch a cell's self-destruct and alarm system?
Cells are coded with several programs for self-destruction. Many cells die peacefully. Others cause a ruckus on their way out.
Mar 10, 2008 - 4:00:00 AM
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Latest Research
Allergic response tied to lipid molecules in cell membrane
A team of Penn State University researchers is the first to demonstrate that lipid molecules in cell membranes participate in mammals' reactions to allergens in a living cell. The finding will help scientists better understand how allergy symptoms are triggered, and could contribute to the creation of improved drugs to treat them. The work will be reported in the 14 March issue of the Journal of Biological Chemistry.
Mar 7, 2008 - 5:00:00 AM
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Latest Research
Scientists successfully treat new mouse model of inflammatory bowel disease
March 6, 2008 -- Researchers trying to improve cancer immune therapy have made an unexpected find: They've produced the most accurate mouse model to date of inflammatory bowel disease (IBD), a cluster of conditions that afflict approximately 1.4 million Americans with abdominal pain, constipation and diarrhea.
Mar 6, 2008 - 5:00:00 AM
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Latest Research
Immune deficiency and balance disorder result from single gene defect
A genetic defect that causes a severe immune deficiency in humans may also produce balance disorders, according to a new study by researchers at the University of Iowa, The Jackson Laboratory and East Carolina University.
Feb 21, 2008 - 5:00:00 AM
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Latest Research
Gene newly linked to inherited ALS may also play role in common dementia
Scientists at Washington University School of Medicine in St. Louis have linked a mutation in a gene known as TDP-43 to an inherited form of amyotrophic lateral sclerosis (ALS), the neurodegenerative condition often called Lou Gehrig's disease.
Feb 20, 2008 - 5:00:00 AM
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Latest Research
Vaccine/antibody therapy effective, milder side effects in melanoma and ovarian cancer
BOSTON--One of the shortcomings of a therapy that uses millions of identical antibodies to boost the immune system's attack on cancer cells is that many patients whose tumors recede in response to the treatment also experience serious inflammatory problems, such as severe diarrhea and rashes. In a new study, a team led by Dana-Farber Cancer Institute researchers shows that giving periodic infusions of such monoclonal antibodies to patients who have received a widely used cancer vaccine unleashes a strong immune response to tumors, with less-harsh side effects.
Feb 18, 2008 - 5:00:00 AM
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Latest Research
Moving an active gene from the interior of the nucleus can silence genes , preventing their transcription . scientists report .
Moving an active gene from the interior of the nucleus to its periphery can inactivate that gene report scientists from the University of Chicago Medical Center .
Feb 14, 2008 - 4:00:00 AM
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Latest Research
Transparent fish to make human biology clearer
Zebrafish are genetically similar to humans and are good models for human biology and disease. Now, researchers at Children's Hospital Boston have created a zebrafish that is transparent throughout its life. The new fish allows scientists to directly view its internal organs, and observe processes like tumor metastasis and blood production after bone-marrow transplant in a living organism.
Feb 6, 2008 - 5:00:00 AM
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Latest Research
T cell immunity enhanced by timing of interleukin-7 therapy
MADISON -- That the cell nurturing growth factor interleukin-7 can help ramp up the ability of the immune system to remember the pathogenic villains it encounters is well known.
Feb 5, 2008 - 8:25:00 AM
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Latest Research
Breakdown of kidney's ability to clean its own filters likely causes disease
Jan. 29, 2008 -- The kidney actively cleans its most selective filter to keep it from clogging with blood proteins, scientists from Washington University School of Medicine in St. Louis reveal in a new study.
Jan 29, 2008 - 5:00:00 AM
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Latest Research
Eczema still on the increase in developing countries
Experts are warning policy makers that allergic disease might replace infectious disease as a major cause of ill health in cities undergoing rapid demographic changes in developing countries.
Jan 7, 2008 - 5:00:00 AM
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Latest Research
More sun exposure may be good for some people
UPTON, NY - A new study by scientists at the U.S. Department of Energy's Brookhaven National Laboratory and colleagues in Norway suggests that the benefits of moderately increased exposure to sunlight - namely the production of vitamin D, which protects against the lethal effects of many forms of cancer and other diseases - may outweigh the risk of developing skin cancer in populations deficient in vitamin D. The study will be published online in the Proceedings of the National Academy of Sciences the week of January 7, 2008.
Jan 7, 2008 - 5:00:00 AM
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Latest Research
2 genes are important key to regulating immune response
NEW YORK (Dec. 28, 2007) -- A research team at Weill Cornell Medical College in New York City has identified two genes that may be crucial to the production of an immune system cytokine called interleukin-10 (IL-10).
Dec 28, 2007 - 5:00:00 AM
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Latest Research
Drug aimed at 2 bioterror agents blocks live viral infection, Weill Cornell team reports
NEW YORK (Dec. 19, 2007) -- Two deadly and highly infectious viruses -- both potential bioterror threats -- may have met their match in a new drug developed by scientists at Weill Cornell Medical College in New York City.
Dec 19, 2007 - 5:00:00 AM
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Latest Research
Dr. Lewis Drusin receives American College of Physicians James D. Bruce Memorial Award
NEW YORK (Dec. 19, 2007) -- In recognition of his distinguished contributions in preventive medicine, epidemiologist Dr. Lewis Drusin of NewYork-Presbyterian Hospital/Weill Cornell Medical Center has been selected by the American College of Physicians to receive the prestigious James D. Bruce Memorial Award, one of 17 awards in internal medicine for 2008.
Dec 19, 2007 - 5:00:00 AM
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Latest Research
Immune system may target some brain synapses, Stanford researchers find
STANFORD, Calif. - A baby's brain has a lot of work to do, growing more neurons and connections. Later, a growing child's brain begins to pare down these connections until it develops into the streamlined brain of an adult.
Dec 13, 2007 - 5:00:00 AM
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Latest Research
Lymphatic vessel and lymph node function are restored with growth factor treatment
The frequent spread of certain cancers to lymph nodes often necessitates surgery or radiation therapy that damages the lymphatic system and can cause lymphedema, a condition of localized fluid retention that often increases susceptibility to infections.
Dec 2, 2007 - 5:00:00 AM
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Latest Research
Poxvirus ability to hide from the immune system may aid vaccine design
The cowpox virus, a much milder cousin of the deadly smallpox virus, can keep infected host cells from warning the immune system that they have been compromised, researchers at Washington University School of Medicine in St. Louis have found. The scientists also showed that more virulent poxviruses, such as the strains of monkeypox prevalent in Central Africa, likely have the same ability.
Nov 15, 2007 - 5:00:00 AM
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Latest Research
Abnormal immune cells may cause unprovoked anaphylaxis
Two new clinical reports shed light on why some people suffer from recurrent episodes of idiopathic anaphylaxis--a potentially life-threatening condition of unknown cause characterized by a drop in blood pressure, fainting episodes, difficulty in breathing, and wheezing.
Nov 9, 2007 - 5:00:00 AM
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Latest Research
Mice help researchers understand chlamydia
Genetically engineered mice may hold the key to helping scientists from Queensland University of Technology and Harvard hasten the development of a vaccine to protect adolescent girls against the most common sexually transmitted disease, Chlamydia.
Oct 29, 2007 - 4:00:00 AM
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Latest Research
Study proposes new theory of how viruses may contribute to cancer
PITTSBURGH, Oct. 23 – A new study suggests that viruses may contribute to cancer by causing excessive death to normal cells while promoting the growth of surviving cells with cancerous traits. Viruses may act as forces of natural selection by wiping out normal cells that support the replication of viruses and leaving behind those cells that have acquired defects in their circuitry. When this process is repeated over and over, cancer can develop say study authors, led by Preet M. Chaudhary, M.D., Ph.D., professor of medicine at the University of Pittsburgh School of Medicine. Their findings are published by Public Library of Science in the Oct. 24 issue of PLoS ONE.
Oct 23, 2007 - 4:00:00 AM
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Latest Research
Hand hygiene initiative aims to decrease healthcare-associated infection in developing countries
An open-access commentary in the December 2007 issue of Infection Control and Hospital Epidemiology examines a recently launched a global initiative by the World Health Organization (WHO) to combat healthcare-associated infection by improving hand hygiene in health care. The commentary is part of the Global Theme Issue on Poverty and Human Development. An international collaboration organized by the Council of Science Editors of simultaneously published research from more than 200 medical and scientific journals , the Global Theme Issue aims to raise awareness of the relationship between poverty and human development.
Oct 22, 2007 - 4:00:00 AM
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Latest Research
Zinc may reduce pneumonia risk in nursing home elderly
BOSTON — When elderly nursing home residents contract pneumonia, it is a blow to their already fragile health. Simin Nikbin Meydani, DVM, PhD of the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University and colleagues report that maintaining normal serum zinc concentration in the blood may help reduce the risk of pneumonia development in that population.
Oct 22, 2007 - 4:00:00 AM
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Latest Research
Scientists discover how gold eases pain of arthritis
DURHAM, N.C. – Scientists at Duke University Medical Center may have solved the mystery surrounding the healing properties of gold – a discovery they say may renew interest in gold salts as a treatment for rheumatoid arthritis and other inflammatory diseases.
Oct 22, 2007 - 4:00:00 AM
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Latest Research
Study reveals 2 genes linked to disabling arthritis
SEATTLE – An international team of researchers led by a Fred Hutchinson Cancer Research Center geneticist has discovered two genes linked to a disabling form of arthritis called ankylosing spondylitis, a painful and progressive disease in which some or all of the spine’s vertebrae fuse together. The researchers also validated the association of two genes implicated in Graves’ disease, an autoimmune condition that causes overactivity of the thyroid gland.
Oct 21, 2007 - 4:00:00 AM
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Latest Research
Major genetic breakthrough for ankylosing spondylitis brings treatment hope
Research funded by the Wellcome Trust and the Arthritis Research Campaign has identified two genes implicated in the disease ankylosing spondylitis, a common disease primarily causing back pain and progressive stiffness. The research, published online today in Nature Genetics, suggests that a treatment currently being trialled for Crohn's disease may also be applied to this disease.
Oct 21, 2007 - 4:00:00 AM
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Latest Research
Immune cells fighting chronic infections become progressively 'exhausted,' ineffective
(PHILADELPHIA) – A new study of immune cells battling a chronic viral infection shows that the cells, called T cells, become exhausted by the fight in specific ways, undergoing profound changes that make them progressively less effective over time.
Oct 18, 2007 - 4:00:00 AM
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Latest Research
Cross-species transplant in rhesus macaques is step toward diabetes cure for humans
St. Louis, Oct. 18, 2007 — With an eye on curing diabetes, scientists at Washington University School of Medicine in St. Louis have successfully transplanted embryonic pig pancreatic cells destined to produce insulin into diabetic macaque monkeys – all without the need for risky immune suppression drugs that prevent rejection.
Oct 18, 2007 - 4:00:00 AM
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Latest Research
West Nile virus' spread through nerve cells linked to serious complication
Oct. 18, 2007 -- Scientists believe they have found an explanation for a puzzling and serious complication of West Nile virus infection.
Oct 18, 2007 - 4:00:00 AM
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Latest Research
Immune cells promote blood vessel formation in mouse endometriosis
A discovery in mice of immune cells that promote the formation of new blood vessels could lead to new treatments for endometriosis, a painful condition associated with infertility that affects up to 15 percent of women of reproductive age.
Oct 18, 2007 - 4:00:00 AM
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Latest Research
Reunion with patient inspires follow-up study on treatment for DiGeorge syndrome
More than 20 years ago, doctors at Mattel Children's Hospital UCLA performed a successful bone marrow transplant on a baby girl who was born without a thymus gland and was suffering from severe immune deficiency. It marked the first time a bone marrow transplant, rather than a thymic transplant, had been used to treat the genetic condition known as DiGeorge Syndrome (DGS).
Oct 16, 2007 - 4:00:00 AM
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Latest Research
Feline virus, antiviral drug studied to understand drug resistance
COLUMBUS , Ohio –Researchers at Ohio State will spend the next two years testing their theories about just how an AIDS-like virus in cats is able to resist the powerful medicines that are thrown against it.
Oct 10, 2007 - 4:00:00 AM
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Latest Research
Influenza: Insights into cell specificity of human vs. avian viruses
Rotterdam, The Netherlands — Researchers have identified which sites and cell types within the respiratory tract are targeted by human versus avian influenza viruses, providing valuable insights into the pathogenesis of these divergent diseases. The report by van Riel et al, “Human and avian influenza viruses target different cells in the lower respiratory tract of humans and other mammals,” appears in the October issue of The American Journal of Pathology and is accompanied by a commentary and highlighted on the cover.
Oct 9, 2007 - 4:00:00 AM
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Latest Research
Accentia announces investigational new drug application for Revimmune for refractory MS
TAMPA, FL—(October 9, 2007)—Accentia Biopharmaceuticals announces that it met with the Food and Drug Administration (FDA) on September 26, 2007 for a scheduled pre-Investigational New Drug (pre-IND) meeting on Revimmune™. The FDA has indicated its support for Accentia to submit an IND for a pivotal Phase 3 randomized controlled, multi-center clinical trial of Revimmune, the company’s potential therapeutic for refractory, relapsing-remitting Multiple Sclerosis (MS). The FDA indicated that they support the proposed submission from Accentia and that they are in overall agreement with the proposed design of the Accentia clinical program.
Oct 9, 2007 - 4:00:00 AM
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Latest Research
Stress contributes to range of chronic diseases, Carnegie Mellon psychologist says
PITTSBURGH -- In a review of the scientific literature on the relationship between stress and disease, Carnegie Mellon University psychologist Sheldon Cohen has found that stress is a contributing factor in human disease, and in particular depression, cardiovascular disease and HIV/AIDS. Cohen’s findings will be published in the Oct. 10 issue of the Journal of the American Medical Association (JAMA). The article was co-authored by Denise Janicki-Deverts of Carnegie Mellon and Gregory E. Miller of the University of British Columbia.
Oct 9, 2007 - 4:00:00 AM
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Latest Research
Patients with pneumonia who received pneumococcal vaccine have lower rate of death, ICU admission
Among patients hospitalized with community-acquired pneumonia, those who had previously received the pneumococcal vaccine had a lower risk of death and admission to the intensive care unit than patients who were not vaccinated, according to a report in the Oct. 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Oct 8, 2007 - 4:00:00 AM
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Latest Research
NIH grant supports UCSF research exploring early HIV infection
A team led by researchers at the UCSF Positive Health Program has been named to receive $15 million over five years to expand understanding of the complex interactions between HIV and the immune systems of newly infected patients following HIV transmission.
Oct 8, 2007 - 4:00:00 AM
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Latest Research
How Candida albicans transforms from its normally benign form into life-threatening form
Researchers at the Agency for Science, Technology and Research's (A*STAR) Institute of Molecular and Cell Biology (IMCB) have discovered new molecular mechanisms that provide a more detailed understanding of how the normally benign Dr. Jekyll-like fungus known as Candida albicans transforms into a serious and often life-threatening Mr. Hyde-like form.
Oct 4, 2007 - 4:00:00 AM
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Latest Research
Scripps research scientists develop innovative dual action anthrax vaccine-antitoxin combination
The immune response generated in rats by the new agent protects against lethal toxin exposure after only one injection, and is faster and stronger than any currently available vaccine.
Oct 4, 2007 - 4:00:00 AM
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Latest Research
Flu vaccine in painless skin patches under development at Emory, Georgia Tech with NIH grants
Flu vaccine delivered through painless microneedles in patches applied to the skin could soon be an alternative to delivery through hypodermic needles, according to researchers at Emory University and the Georgia Institute of Technology. Using new grants from the National Institutes of Health (NIH) totaling approximately $11.5 million over five years, researchers from the two institutions plan to develop a new vaccine product using the microscopic needles.
Oct 3, 2007 - 4:00:00 AM
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Latest Research
New test could help consumers avoid surprise headaches from chocolate, wine
Researchers in California are reporting development of a fast, inexpensive test suitable for home use that could help millions of people avoid those ‘out of the blue’ headaches that may follow consumption of certain red wines, cheese, chocolate, and other aged or fermented foods.
Oct 1, 2007 - 4:00:00 AM
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