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Last Updated: Jan 10, 2011 - 8:52:29 PM |
Latest Research
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Haematology
Particles created which may help in the development of synthetic blood
University of North Carolina at Chapel Hill researchers used technology known as PRINT (Particle Replication in Non-wetting Templates) to produce very soft hydrogel particles that mimic the size, shape and flexibility of red blood cells, allowing the particles to circulate in the body for extended periods of time.
Jan 10, 2011 - 8:44:51 PM
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Latest Research
Early safety results promising for Phase I/II trial of gene therapy treatment of hemophilia B
Investigators report no evidence of toxicity in the four hemophilia B patients enrolled to date in a gene therapy trial using a vector under development at St. Jude Children's Research Hospital and UCL (University College London) to correct the inherited bleeding disorder.
Dec 6, 2010 - 5:00:00 AM
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Latest Research
2 studies provide insight into stroke risk and prevention in young sickle cell anemia patients
Monthly blood transfusions combined with daily medication to remove the resulting excess iron remains the best approach for reducing the risk of recurrent strokes in young patients with sickle cell anemia, according to a preliminary analysis of a multicenter trial that includes St. Jude Children's Research Hospital.
Dec 6, 2010 - 5:00:00 AM
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Latest Research
Mathematical model of the life cycle of red blood cells may predict risk of anemia
A collaboration between a physician-researcher at Massachusetts General Hospital (MGH) and a mathematician from Harvard University has led to development of a mathematical model reflecting how red blood cells change in size and hemoglobin content during their four-month lifespan. In their report published online in PNAS Early Edition, John Higgins, MD, MGH Center for Systems Biology and Department of Pathology, and L. Mahadevan, PhD, Harvard School of Engineering and Applied Sciences (SEAS), also describe how their model may be used to provide valuable clinical information.
Nov 12, 2010 - 5:00:00 AM
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Latest Research
Key to blood-brain barrier opens way for treating Alzheimer's and stroke
While the blood-brain barrier (BBB) protects the brain from harmful chemicals occurring naturally in the blood, it also obstructs the transport of drugs to the brain. In an article in Nature scientists at the Swedish medical university Karolinska Institutet now present a potential solution to the problem. The key to the BBB is a cell-type in the blood vessel walls called pericytes, and the researchers hope that their findings will one day contribute to new therapies for diseases like Alzheimer's and stroke.
Oct 14, 2010 - 4:00:00 AM
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Latest Research
Filtering donor blood reduces heart, lung complications
Researchers at the University of Rochester Medical Center (URMC) have discovered yet another reason to filter the foreign white cells from donor blood: The resulting blood product is associated with dramatically fewer cardiopulmonary complications for patients who received a transfusion.
Jun 22, 2010 - 4:00:00 AM
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Latest Research
NHLBI funds research to improve safety of red blood cell transfusions
The National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health, is funding nine research grants to determine if the safety and efficacy of red blood cell transfusions vary depending on how long the cells have been stored. One of the grants supports the first large, multi-center, randomized clinical trial to compare outcomes in heart surgery patients who receive transfusions of red blood cells that have been stored for shorter or longer amounts of time. The other eight research grants provide about $3.9 million per year over four years to assess the safety and efficacy of red blood cell transfusions.
Jun 21, 2010 - 4:00:00 AM
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Latest Research
Stroke prevention study in children with sickle cell anemia, iron overload stopped early
The National Heart, Lung, and Blood Institute (NHLBI) has stopped a clinical trial evaluating a new approach to reduce the risk of recurrent stroke in children with sickle cell anemia and iron overload because of evidence that the new treatment was unlikely to prove better than the existing treatment.
Jun 4, 2010 - 4:00:00 AM
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Latest Research
NHLBI, CDC launch surveillance and research program for inherited blood diseases
Medical researchers are developing a new surveillance system to determine the number of patients diagnosed with a family of inherited blood disorders known as hemoglobinopathies, including sickle cell disease, thalassemias, and hemoglobin E disease.
Feb 18, 2010 - 5:00:00 AM
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Latest Research
Researchers revisit pulmonary arterial hypertension survival
Setting out to determine the survival of patients with pulmonary arterial hypertension (PAH), researchers at the University of Chicago Medical Center and their colleagues also discovered that an equation used for more than 20 years to predict survival is outdated. Accordingly, they developed and recently published a new survival prediction equation that will impact clinical practice and the drug development process.
Jan 6, 2010 - 4:59:36 AM
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Latest Research
H1N1 more risky than seasonal flu in children with sickle cell disease
Infection with the H1N1 virus, or swine flu, causes more life-threatening complications than seasonal flu in children with sickle cell disease, according to research from Johns Hopkins Children's Center. The findings, to be presented on Dec. 7 at the annual meeting of the American Society of Hematology, warn parents and caregivers that such children are more likely to need emergency treatment and stays in an intensive-care unit.
Dec 7, 2009 - 5:00:00 AM
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Latest Research
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Haematology
Vital discovery may save many from traumatic deaths
Researchers have unravelled how certain proteins can enter the bloodstream and begin to kill the lining of blood vessels, resulting in uncontrolled internal bleeding. Their discovery could help save thousands from traumatic deaths, caused by car crashes or on the battlefield.
Nov 5, 2009 - 3:06:44 PM
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Latest Research
The American Society of Hematology to honor inspirational hematologists with Mentor Awards
(WASHINGTON, November 3, 2009) - The American Society of Hematology (ASH) is honoring two prominent hematologists with ASH Mentor Awards in recognition of the important role they play in the training and career development of hematologists early in their careers. Stuart H. Orkin, MD, and Arthur W. Nienhuis, MD, will receive their awards during the 51st ASH Annual Meeting in New Orleans.
Nov 3, 2009 - 5:00:00 AM
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Latest Research
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Cardiology
Transfusions Risky For Cardiac Patients
Blood transfusion to hospitalised cardiac patients doubles the risk of infection and quadruples the risk of death, according to a new study.
Aug 8, 2009 - 1:45:47 PM
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Latest Research
NHLBI stops study of pulmonary hypertension treatment in sickle cell patients
The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health has stopped a clinical trial testing a drug treatment for pulmonary hypertension in adults with sickle cell disease nearly one year early due to safety concerns. In an interim review of safety data from 33 participants who completed 16 weeks of treatment, researchers found that, compared to participants on placebo (dummy pill), participants taking sildenafil (Revatio) were significantly more likely to have serious medical problems. The most common problem was episodes of severe pain called sickle cell crises, which resulted in hospitalization. No deaths have been associated with the drug in the clinical trial.
Jul 28, 2009 - 4:00:00 AM
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Latest Research
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Cardiology
Anemia linked with higher death risk in heart patients
The presence of anaemia in patients with chronic heart failure is linked to a significantly higher risk of death.
Jun 18, 2009 - 3:42:28 PM
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Latest Research
Common chemotherapy drug triggers fatal allergic reactions
CHICAGO -- A chemotherapy drug that is supposed to help save cancer patients' lives, instead resulted in life-threatening and sometimes fatal allergic reactions.
Jun 8, 2009 - 4:00:00 AM
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Latest Research
Canadian biomedical engineering pioneer receives international award
Countless individuals around the world are alive because of him. His 40 plus years of research have helped to make the use of life-saving devices such as prosthetic heart valves, vascular stents, vascular grafts, heart-assist devices, and heart-lung bypass systems almost commonplace. In the process, he has helped to establish Canada as a biomaterials leader.
Apr 23, 2009 - 4:00:00 AM
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Latest Research
Potential breakthrough for T-Cell lymphoma patients with drug that mimics folic acid
NEW YORK (Dec. 8, 2008) -- Preliminary results of a pivotal Phase 2 clinical trial of pralatrexate (PDX), a drug that partially works by mimicking folic acid, showed a complete or partial response in 27 percent of patients with recurrent or resistant peripheral T-cell lymphoma (PTCL). PROPEL (Pralatrexate in patients with Relapsed Or refractory PEripheral T-cell Lymphoma) findings were presented by the study's principal investigator, Dr. Owen A. O'Connor of the Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center and NewYork-Presbyterian Hospital, at the 50th Annual Meeting of the American Society of Hematology (ASH) in San Francisco.
Dec 9, 2008 - 5:00:00 AM
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Latest Research
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Haematology
Bone marrow stem cell niche discovered
Researchers have identified the precise location of the bone marrow stem cell niche.
Dec 7, 2008 - 5:36:33 PM
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Latest Research
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Haematology
Transcranial Doppler ultrasonography screening helps in preventing strokes in children with sickle cell disease
Screening with an ultrasound machine has proved highly successful in preventing stroke among children with sickle cell disease, by identifying children who are then preventively treated with blood transfusions. Over an eight-year period at The Children's Hospital of Philadelphia, researchers found that the technique, transcranial Doppler ultrasonography (TCD), along with regular transfusions for children found to be at high risk, reduced stroke to one-tenth of the incidence found before TCD was introduced.
Dec 7, 2008 - 2:10:44 PM
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Latest Research
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Haematology
Evaluation of new anti-coagulant drugs
The largest study ever to examine the preventive use of blood-thinning medication to help prevent deadly blood clots in patients with cancer undergoing chemotherapy was presented in a press conference during the 50th Annual Meeting of the American Society of Hematology in San Francisco, CA. Additional research featured at the press conference includes studies that examine the use of three different investigational blood-thinning medications that belong to a new class of therapies called Factor Xa inhibitors.
Dec 7, 2008 - 2:02:09 PM
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Latest Research
Researchers aim to over-stress already taxed mantle cell lymphoma cells
AUGUSTA, Ga. - Cancer cells are already stressed by the fast pace they require to grow and spread and scientists believe a little more stress just may kill them.
Nov 10, 2008 - 5:00:00 AM
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Latest Research
'Old blood' linked to infection
Blood stored for 29 days or more, nearly 2 weeks less than the current standard for blood storage, is associated with a higher infection rate in patients who received transfusions with the blood. In a new study presented at CHEST 2008, the 74th annual international scientific assembly of the American College of Chest Physicians (ACCP), researchers found that patients who received transfusions with blood stored for 29 days or more were twice as likely to suffer from nosocomial infections, including pneumonia, upper respiratory infections, and sepsis, with the oldest blood being associated with the most infections. Currently, federal regulations allow red blood cells to be stored up to 42 days, after which they must be discarded.
Oct 28, 2008 - 4:00:00 AM
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Latest Research
Einstein and Montefiore receive grants to expand disease-focused stem cell research
The Empire State Stem Cell Board has awarded research planning grants to Albert Einstein College of Medicine and to Montefiore Medical Center. The grants, totaling $238,000, are part of $2 million in grants announced by State Health Commissioner Richard F. Daines, M.D. The funding, awarded to 18 medical colleges, medical centers and labs will strengthen New York State's capacity for stem cell research and could lead to the development of new therapies for Alzheimer's, diabetes, Parkinson's, ALS and other conditions.
Oct 3, 2008 - 4:00:00 AM
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Latest Research
High blood pressure takes big toll on small filtering units of the kidney
Take a kidney out of the body and it still knows how to filter toxins from the blood.
Sep 19, 2008 - 4:00:00 AM
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Latest Research
Better understanding of blood vessel constrictor needed to harness its power for patients
To harness endothelin-1's power to constrict blood vessels and help patients manage high blood pressure or heart failure, scientists must learn more about how endothelin functions naturally and in disease states, says a Medical College of Georgia researcher.
Sep 18, 2008 - 4:00:00 AM
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Latest Research
'Cancer was one of the best things to happen to me... but I worry about the future'
London, UK: For Dan Savage, surviving testicular cancer has been a spur to him making the most of his life and taking more adventurous decisions, and he says, that in retrospect, it was probably one of the best things that has happened to him. But as he approaches the end of his fifth year in remission from the disease, when he will be signed off as cured by the medical profession, he worries that from now on he will have no regular medical checks that might pick up early signs of the cancer returning. It will be down to him to contact the cancer clinic if he is worried about any new symptoms.
Jun 10, 2008 - 4:00:00 AM
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Latest Research
Cancer incidence and mortality in young people decreases with increasing deprivation
London, UK: Results of research into the associations between cancer and socio-economic deprivation and affluence have shown that, in contrast to cancers in older people, the numbers of new cases and deaths from the disease in teenagers and young adults (TYAs) decrease with increasing deprivation.
Jun 9, 2008 - 4:00:00 AM
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Latest Research
Teenagers and young adults with cancer can face long delays before finally being diagnosed
London, UK: Three studies to be presented at Teenage Cancer Trust's Fifth International Conference on Teenage and Young Adult Cancer Medicine today (Monday) have thrown light on the extent of delays that teenagers and young adults (TYAs) can face before being diagnosed with cancer, and on some of the reasons why this happens.
Jun 8, 2008 - 4:00:00 AM
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Latest Research
First early-detection blood test for Parkinson's shows promise
NEW YORK (March 11, 2008) -- A test that profiles molecular biomarkers in blood could become the first accurate diagnostic test for Parkinson's disease, new research shows.
Mar 11, 2008 - 4:00:00 AM
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Latest Research
Eltrombopag effective for hepatitis C patients with low blood-platelet counts
NEW YORK (Dec. 28, 2007) -- For patients with hepatitis C, having a low blood platelet count is a frequent complication associated with advanced disease. This problem is compounded by the fact that standard antiviral treatment for the disease can further reduce platelet numbers to dangerously low levels, effectively denying these patients the treatment they urgently need. Now, research published in the New England Journal of Medicine finds that a new drug, eltrombopag, appears to significantly boost platelet counts, opening the door to effective treatment.
Dec 28, 2007 - 5:00:00 AM
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Latest Research
Light and sound -- the way forward for better medical imaging
Detection and treatment of tumours, diseased blood vessels and other soft-tissue conditions could be significantly improved, thanks to an innovative imaging system being developed that uses both light and sound.
Dec 12, 2007 - 5:00:00 AM
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Latest Research
Children with sickle cell disease, silent strokes show some relief with blood transfusions
A group of children who have sickle cell disease and who experience silent strokes showed some relief from the silent strokes with blood transfusion therapy, researchers at Washington University School of Medicine in St. Louis have found.
Dec 10, 2007 - 5:00:00 AM
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Latest Research
Study proposes new theory of how viruses may contribute to cancer
PITTSBURGH, Oct. 23 – A new study suggests that viruses may contribute to cancer by causing excessive death to normal cells while promoting the growth of surviving cells with cancerous traits. Viruses may act as forces of natural selection by wiping out normal cells that support the replication of viruses and leaving behind those cells that have acquired defects in their circuitry. When this process is repeated over and over, cancer can develop say study authors, led by Preet M. Chaudhary, M.D., Ph.D., professor of medicine at the University of Pittsburgh School of Medicine. Their findings are published by Public Library of Science in the Oct. 24 issue of PLoS ONE.
Oct 23, 2007 - 4:00:00 AM
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Latest Research
Chemistry turns killer gas into potential cure
Despite its deadly reputation, the gas carbon monoxide (CO) could actually save lives and boost health in future as a result of leading-edge UK research.
Oct 15, 2007 - 4:00:00 AM
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Latest Research
Anticlotting drug found to be safe in sickle cell patients
CHAPEL HILL - An intravenous “blood thinner” widely used in patients with acute coronary syndromes and during coronary artery stent placement appears to be safe in patients with sickle cell disease and may have beneficial anti-inflammatory effects, a small study at the University of North Carolina at Chapel Hill School of Medicine has found.
Oct 11, 2007 - 4:00:00 AM
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Latest Research
MIT uncovers key blood protein
CAMBRIDGE, MA--Scientists working in the only lab at MIT doing hematology research have uncovered a protein that plays a key role in the recycling of iron from blood.
Oct 11, 2007 - 4:00:00 AM
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Latest Research
Daisies lead scientists down path to new leukemia drug
A new, easily ingested form of a compound that has already shown it can attack the roots of leukemia in laboratory studies is moving into human clinical trials, according to a new article by University of Rochester investigators in the journal, Blood.
Oct 2, 2007 - 4:00:00 AM
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Latest Research
Novel strategy under study for aggressive leukemia
A novel strategy to hopefully beat into oblivion one of the most aggressive forms of acute myelogenous leukemia combines the strengths of some of the newest leukemia agents, researchers say.
Sep 24, 2007 - 4:00:00 AM
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Latest Research
Sexual function affected by stem cell transplant according to long-term study
WASHINGTON, Sept. 18, 2007 -- A long-term study found that a type of stem cell transplant used for patients with life-threatening diseases, such as leukemia and lymphoma, results in decreased sexual function and activity for recipients. Further, males are likely to recover from these changes over time, while the sexuality of female patients remains compromised. In addition, neither male nor female long-term cancer survivors regained levels of sexual activity and function equal to those of their peers who have not had cancer, according to a Blood First Edition Paper prepublished online today. Blood is the official journal of the American Society of Hematology.
Sep 18, 2007 - 4:00:00 AM
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Latest Research
Unique role for blood formation gene identified
Hanover, NH--All blood cell production in adults depends on the steady work of a vital gene that if lost results in early bone marrow failure, Dartmouth Medical School cancer geneticists have found. Their research reveals an unexpected role for the gene in sustaining the adult blood-forming system, and opens novel strategies for targeting the gene, which is often involved in a type of childhood leukemia.
Sep 12, 2007 - 4:00:00 AM
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Latest Research
Small animal imaging facility is big boon to research
When powerful magnets line up the body’s protons before radiofrequency waves can grab their attention away, it’s called spin physics.
Aug 30, 2007 - 4:00:00 AM
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Latest Research
New cancer fighter may help ICU patients beat infections
HSP 90 inhibitors, which are finding favor in fighting cancer, may also help battle overwhelming infection in intensive care patients, researchers say.
Aug 27, 2007 - 4:00:00 AM
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Latest Research
Bench-to-bedside look at MSC research at Case Western Reserve conference in Cleveland
CLEVELAND—Researchers from 22 countries will come to Cleveland for a bench to bedside examination of the developing mesenchymal stem cells (MSC) from regenerative medicine and stem cell research to therapeutics in patient care. The National Center for Regenerative Medicine for Stem Cell and Regenerative Medicine (NCRM) and founding partner Case Western Reserve University have organized the 2007 Adult Mesenchymal Stem Cells in Regenerative Medicine Conference, August 27-29, at the Marriott Hotel in downtown Cleveland, to highlight advances in MSC research. The conference is the first organized by the two groups on MSCs.
Aug 24, 2007 - 4:00:00 AM
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Latest Research
Better life support for artificial liver cells
COLUMBUS , Ohio -- Researchers at Ohio State University are developing technology for keeping liver cells alive and functioning normally inside bioartificial liver-assist devices (BLADs).
Aug 23, 2007 - 4:00:00 AM
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Latest Research
Tumors use enzyme to recruit regulatory T-cells and suppress immune response
One way tumors fly under the radar of the immune system is by using IDO, an enzyme used by fetuses to help avoid rejection, to recruit powerful regulatory T cells that turn down the immune response, researchers say.
Aug 16, 2007 - 4:00:00 AM
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Latest Research
New study shows promise in reducing surgical risks associated with surgical bleeding
CHICAGO (August 10, 2007) – Surgeons may have a new patient safety tool to stop moderate surgical bleeding without some of the concerns associated with the current standard blood-clotting treatment. New research published in the August issue of the Journal of the American College of Surgeons shows that recombinant human thrombin (rhThrombin) reduces the risk of surgical complications associated with the use of plasma-derived bovine thrombin (bThrombin), which is currently the only commercially available stand-alone thrombin used to improve clotting during surgical procedures and stop bleeding.
Aug 10, 2007 - 4:00:00 AM
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Latest Research
Teamwork between 2 key proteins necessary for normal development and regulation of red blood cells
RICHMOND, Va. (Aug. 6, 2007) – Virginia Commonwealth University researchers studying hemoglobin genes, mutations of which play a role in genetic blood disorders like sickle cell anemia and beta-thalassemia, have identified two proteins that are responsible for regulating overlapping groups of genes during the development of red blood cells.
Aug 6, 2007 - 4:00:00 AM
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Latest Research
Study shows radiofrequency ablation highly effective in treating kidney tumors
The patients underwent CT-guided radiofrequency ablation (RFA) at Wake Forest Baptist for kidney tumors ranging in size from 0.6 cm to 8.8 cm. A total of 125 tumors in 104 patients were treated over the period 2000 to 2006. In all of the patients, a biopsy had confirmed the presence of renal cell carcinomas (RCC), a common type of renal malignancy.
Aug 1, 2007 - 4:00:00 AM
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| Health |
Best way to boost adult immunizations is through office-based action, study finds
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'Pep talk' can revive immune cells exhausted by chronic viral infection
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Burning more sugar drives super athleticism
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Research aims to prevent obesity by reaching parents, young children through child care
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AMD-like lesions delayed in mice fed lower glycemic index diet
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Low vitamin C levels may raise heart failure patients' risk
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Sugar-sweetened beverages may increase cardiovascular risk in women
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Study finds shifting disease burden following universal Hib vaccination
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UT study: Climate change affects ants and biodiversity
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Dirt prevents allergy
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| | Healthcare |
Fitness club memberships help insurance plans to enrol healthier patients
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Anxiety disorders mount since credit crunch
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Doctors diagnose patients within moments of meeting
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Physician-defined patient complexity differs from current diagnosis-based measures
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Free health screening for school children Nov 14
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Systematic bias in the assessment of UK doctors
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White children far more likely to receive CT scans than Hispanic, African-American children
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Suspected brain disease kills 51 kids in Bihar
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New rules for bio-medical waste management in India
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Delhi hospitals lacking in emergency protocols
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| | Latest Research |
New device performs better than old for removing blood clots
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Gene related to fat preferences in humans found
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Cardiovascular Nursing Spring Meeting
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The effect of occasional binge drinking on heart disease and mortality among moderate drinkers
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ORNL, partners earn FLC honor for cookstove technology
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Clot-busting drugs appear safe for treating 'wake-up' stroke patients
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Infections in childhood linked to high risk of ischemic stroke
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Penn State scientists elected to American Geophysical Union
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Wayne State University project aims to reduce HIV, AIDS among African-Americans
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Scientists help define structure of exoplanets
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| | Medical News |
Women delivers baby near lift in Noida hospital
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Obesity on rise in school children: Study
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Over 10,000 dengue cases in India this year
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NRI doctors demands removal of 'tainted' medical council members
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Watch out for sexually transmitted 'superbug': Expert
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Panel stresses on infection control in hospitals
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Healthcare cost up 22 times in rural areas, shows study
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Superbug exists, but nothing alarming: Walia
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No power problem at AIIMS: Official
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40 percent Indians embarrassed to ask for contraceptives
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| | Special Topics |
Behold India's unfolding democratic revolution
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Chinese woman cuts open her belly to save surgery cost
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Improved Sense of Smell Produced Smarter Mammals
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Two-year-old world's first to have extra DNA strand
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172,155 kidney stones removed from one patient!
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'Primodial Soup' theory for origin of life rejected in paper
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Human species could have killed Neanderthal man
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History, geography also seem to shape our genome
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3,000 Kerala medical students to attend inter-college meet
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Tamil Nadu seeks to control deemed universities
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