|Last Updated: Nov 2, 2013 - 11:52:55 AM
Breathing new life into preterm baby research
Monash University researchers have received a prestigious National Institutes of Health (NIH) project grant to find ways to improve outcomes for very preterm infants who struggle to take their first breaths.
Oct 8, 2013 - 4:00:00 AM
Penn Medicine study: Proton therapy cuts side effects for pediatric head and neck cancer patients
ATLANTA -- The precise targeting and limited dosing of radiation via proton therapy is proving to be an advantage in ongoing efforts to reduce treatment side effects among head and neck cancer patients, according to a new study of pediatric patients from researchers at the Perelman School of Medicine at the University of Pennsylvania. The results were presented Monday at the 55th annual meeting of the American Society for Radiation Oncology (ASTRO) conference.
Sep 24, 2013 - 4:00:00 AM
NJ State House honors NJIT student inventors of autism app
NJIT Distinguished Professor Atam P. Dhawan, PhD, recently joined the autism community at the NJ State House to be recognized for improving public and private autism services. Dhawan, a noted electrical engineer and inventor in his own right, who heads NJIT's Interdisciplinary Design Studio (IDS) program, is also executive director of undergraduate research and innovation at NJIT. The IDS program is offered to Albert Dorman Honors College students at NJIT.
Sep 16, 2013 - 4:00:00 AM
Researchers from Mount Sinai receive NIH grant to study promising treatment for Autism subtype
Scientists at the Seaver Autism Center at the Icahn School of Medicine at Mount Sinai have received a grant from the National Institutes of Health (NIH) to study Insulin-Like Growth Factor-1 (IGF-1), a promising treatment for a subtype of autism called Phelan McDermid Syndrome (PMS). The grant will allow researchers to expand upon an ongoing study assessing the clinical benefit of IGF-1 in children with this severe type of autism.
Aug 26, 2013 - 4:00:00 AM
Brain size may signal risk of developing an eating disorder
AURORA, Colo. (August 22, 2013) - New research indicates that teens with anorexia nervosa have bigger brains than teens that do not have the eating disorder. That is according to a study by researchers at the University of Colorado's School of Medicine that examined a group of adolescents with anorexia nervosa and a group without. They found that girls with anorexia nervosa had a larger insula, a part of the brain that is active when we taste food, and a larger orbitofrontal cortex, a part of the brain that tells a person when to stop eating.
Aug 21, 2013 - 4:00:00 AM
Chromosome 21 abnormality tells oncologists to treat pediatric ALL more aggressively
A recent study by members of the Children's Oncology Group reports results of a large trial showing that children whose leukemia cells have amplification of a portion of chromosome 21 may require more aggressive treatment for Acute Lymphoblastic Leukemia (ALL) than children without this gene amplification.
Aug 20, 2013 - 4:00:00 AM
HudsonAlpha awarded grant to improve diagnoses of childhood genetic disorders
HUNTSVILLE, Ala -- Even in the absence of a ready solution, knowing why a child faces physical, emotional and intellectual challenges is helpful to physicians and families. Researchers at the HudsonAlpha Institute for Biotechnology are using high throughput genomic sequencing to meet major diagnostic needs for childhood genetic disorders through a multi-year grant potentially totaling more than $7.6 million from the National Institutes of Health.
Jul 23, 2013 - 4:00:00 AM
Insights into how brain compensates for recurring hearing loss point to new glue ear therapies
Important new insights into how the brain compensates for temporary hearing loss during infancy, such as that commonly experienced by children with glue ear, are revealed in a research study in ferrets. The Wellcome Trust-funded study at the University of Oxford could point to new therapies for glue ear and has implications for the design of hearing aid devices.
Jun 27, 2013 - 4:00:00 AM
CWRU study finds babies witnessing violence show aggression later in school
Aggression in school-age children may have its origins in children 3 years old and younger who witnessed violence between their mothers and partners, according to a new Case Western Reserve University study.
Jun 17, 2013 - 4:00:00 AM
Mayo Clinic first in US to test stem cells in pediatric congenital heart disease patients
ROCHESTER, Minn. -- Mayo Clinic has announced the first U.S. stem cell clinical trial for pediatric congenital heart disease. The trial aims to determine how stem cells from autologous umbilical cord blood can help children with hypoplastic left heart syndrome (HLHS), a rare defect in which the left side of the heart is critically underdeveloped.
Jun 11, 2013 - 4:00:00 AM
St. Jude scientist named Howard Hughes Medical Institute investigator
Michael Dyer, Ph.D., a scientist at St. Jude Children's Research Hospital, has been selected as a Howard Hughes Medical Institute (HHMI) investigator. Dyer is one of 27 scientists nationwide chosen for the recognition from among 1,155 applicants. There are approximately 330 HHMI investigators in the United States, and Dyer will become the third of these investigators currently working at St. Jude.
May 9, 2013 - 4:00:00 AM
Parents who suck on their infants' pacifiers may protect their children against developing allergy
Swedish researchers at the Sahlgrenska Academy, University of Gothenburg, Sweden, report that a simple habit may give significant protection against allergy development, namely, the parental sucking on the baby's pacifier.
May 7, 2013 - 4:00:00 AM
Finding genes for childhood obesity
Researchers have identified four genes newly associated with severe childhood obesity. They also found an increased burden of rare structural variations in severely obese children.
Apr 7, 2013 - 4:00:00 AM
Researchers to develop next generation immunotherapy for children with deadly solid tumors
Recently, research using adoptive T-cell immunotherapy in blood cancers have shown success, most notably in the case of a seven-year-old girl whose leukemia went into remission using altered T-cells and a disabled HIV virus. Now, two of the pediatric cancer scientists involved in the T-cell/HIV study will develop a new experimental cancer immunotherapy treatment option for children with high-risk solid tumors based on the same novel approach that uses a patient's own T-cells to attack tumor cells.
Apr 3, 2013 - 4:00:00 AM
Nerve damage may underlie widespread, unexplained chronic pain in children
Massachusetts General Hospital (MGH) investigators have described what may be a newly identified disease that appears to explain some cases of widespread chronic pain and other symptoms in children and young adults. Their report that will appear in the April issue of the journal Pediatrics, and has received early online release, finds that most of a group of young patients seen at the MGH for chronic, unexplained pain had test results indicating small-fiber polyneuropathy, a condition not previously reported in children. The MGH investigators call this new syndrome juvenile-onset small-fiber polyneuropathy or JOSeFINE.
Mar 11, 2013 - 4:00:00 AM
Pediatric cancer charities partner to fund international collaborative research
Solving Kids' Cancer, along with U.K.-based charities Neuroblastoma Alliance UK, J-A-C-K, and other European organizations have aligned forces to improve access to promising clinical trials for children with high-risk neuroblastoma in North America, the U.K. and Europe. The aim of the International Neuroblastoma Research Collaborative (INBRC) is to bring the cancer research community together to produce immunotherapy options to treat, control and prevent the recurrence of neuroblastoma in children. The new initiative mandates a collaboration of international cancer centers, offering a grant award of up to $500,000 (USD).
Mar 4, 2013 - 5:00:00 AM
MSU launches groundbreaking drug trial in Africa
Determined to bring relief to seizure victims, a Michigan State University research team this month begins a groundbreaking clinical drug trial that could help prevent a quarter-million African children from developing epilepsy each year.
Feb 15, 2013 - 5:00:00 AM
MIND Institute researchers receive $1 million grant to study cognitive training in fragile X
Researchers at the UC Davis MIND Institute will examine whether children and youth with fragile X syndrome can improve their working memory, cognition and behavior by using an online computer-based cognitive training program, through a new $1 million grant from The John Merck Fund.
Feb 13, 2013 - 5:00:00 AM
Institute of Medicine report details for monitoring safety of childhood immunization schedule
ANN ARBOR -- A review of the available evidence underscores the safety of the federal childhood immunization schedule, according to a report released today by the Institute of Medicine. University of Michigan population ecologist Pejman Rohani served on the 13-person committee that wrote the report.
Jan 16, 2013 - 5:00:00 AM
Engineered immune cells produce complete response in child with an aggressive pediatric leukemia
By reprogramming a 7-year-old girl's own immune cells to attack an aggressive form of childhood leukemia, a pediatric oncologist has achieved a complete response in his patient, who faced grim prospects when she relapsed after conventional treatment. The innovative experimental therapy used bioengineered T cells, custom-designed to multiply rapidly in the patient, and then destroy leukemia cells. After the treatment, the child's doctors found that she had no evidence of cancer.
Dec 9, 2012 - 5:00:00 AM
UMass Medical School enrolling participants in National Children's Study pilot program
WORCESTER, MA -- UMass Medical School is enrolling expectant mothers from Worcester County in a pilot program in preparation for the much larger National Children's Study, the landmark undertaking in which 100,000 children will be followed from the womb to age 21 to determine the environment's impact on growth, development and onset of disease.
Dec 5, 2012 - 5:00:00 AM
CWRU dental and nursing students collaborate for 'one-stop' healthcare
Patients in dental chairs at the Case Western Reserve University School of Dental Medicine will see something new: a nurse.
Nov 20, 2012 - 5:00:00 AM
Whole genome sequencing of de novo balanced rearrangements in prenatal diagnosis
Whole genome sequencing of the DNA code of three prenatal samples provided a detailed map of the locations of their chromosomal abnormalities in 14 days, scientists reported today at the American Society of Human Genetics (ASHG) 2012 meeting in San Francisco.
Nov 7, 2012 - 5:00:00 AM
DNA sequencing of infants and children with anatomical defects of unknown causes
A presentation at the American Society of Human Genetics 2012 meeting updated genetics experts about a one-year-old research initiative that brought together researchers, clinicians and policy experts to tackle the challenges of incorporating new genomic technologies into clinical care of newborns, infants and children with anatomical defects whose causes are unknown.
Nov 6, 2012 - 5:00:00 AM
Gene linked to inflammation in the aorta may contribute to abdominal aortic aneurysm
A gene known to be involved in cancer and cardiovascular development may be the cause of inflammation in the most common form of aortic aneurysm and may be a key to treatment, according to research from Nationwide Children's Hospital. The study, appearing online in Arteriosclerosis, Thrombosis, and Vascular Biology on October 18, 2012, is the first to show that Notch 1 signaling is activated in abdominal aortic aneurysmal tissue in mice and humans.
Oct 24, 2012 - 4:00:00 AM
New intervention may help identify and improve care for adolescents at risk for suicide
Investigators at Nationwide Children's Hospital and Cincinnati Children's Hospital Medical Center are hoping to better identify adolescents at risk for suicide and improve how these at-risk children receive follow up mental health treatment. Thanks to a $1.2 million grant from the Centers for Disease Control and Prevention, the two hospitals will conduct a three-year study to test a new intervention targeting adolescents during emergency department visits.
Oct 3, 2012 - 4:00:00 AM
Genetic test predicts risk for Autism
A team of Australian researchers, led by University of Melbourne has developed a genetic test that is able to predict the risk of developing Autism Spectrum Disorder, ASD.
Sep 11, 2012 - 4:00:00 AM
Adolescent pot use leaves lasting mental deficits
DURHAM, N.C. -- The persistent, dependent use of marijuana before age 18 has been shown to cause lasting harm to a person's intelligence, attention and memory, according to an international research team.
Aug 27, 2012 - 4:00:00 AM
NCH CIRP awarded CDC Injury Control Research Center designation, another 5 years
The Centers for Disease Control and Prevention (CDC) has renewed the designation of the Center for Injury Research and Policy (CIRP) of The Research Institute at Nationwide Children's Hospital as one of the agency's Injury Control Research Centers (ICRCs). This renewal follows a highly competitive review process of applications by research centers from across the country. It reaffirms CIRP's role as a national leader in the areas of pediatric injury research, education and training, and community outreach.
Aug 13, 2012 - 4:00:00 AM
Piglets in mazes provide insights into human cognitive development
URBANA -- Events that take place early in life almost certainly have consequences for later cognitive development. Establishing the connections is difficult, however, because human infants cannot be used as laboratory subjects.
Jul 25, 2012 - 4:00:00 AM
Blood condition is highly predictive of graft failure in pediatric kidney transplant
For children receiving kidney transplants, a potentially correctable blood condition present in about one in four recipients is associated with a moderately increased risk of the graft's later failure, suggesting that clinicians should weigh whether transplant is advisable when the condition is present, according to UC Davis research presented today at the 24th International Congress of the Transplantation Society in Berlin.
Jul 19, 2012 - 4:00:00 AM
Mount Sinai finds that oral immunotherapy shows promise as treatment for children with egg allergy
A team of researchers from Mount Sinai School of Medicine and four other institutions have found that young children with egg allergies can benefit from treatment with oral immunotherapy. The study titled, Oral Immunotherapy for Treatment of Egg Allergy in Children, appears online in the New England Journal of Medicine on Wednesday, July 19.
Jul 18, 2012 - 4:00:00 AM
ACL reconstruction technique improves outcomes in pediatric patients
A new study demonstrates the superiority of a specific technique to perform anterior cruciate ligament (ACL) reconstruction in children. In recent years, the number of ACL surgeries in pediatric athletes has skyrocketed.
Jul 13, 2012 - 4:00:00 AM
Parents seen as critical stakeholders in expanding newborn screening
Parents must be considered when states decide to expand genetic screening programs for newborns, according to a new study that looked at mandatory testing panels and political pressure by advocacy groups.
Jun 21, 2012 - 4:00:00 AM
Infants can't distinguish between large and small groups
COLUMBIA, Mo. -- Human brains process large and small numbers of objects using two different mechanisms, but infants have not yet developed the ability to make those two processes work together, according to new research from the University of Missouri.
Jun 19, 2012 - 4:00:00 AM
NYU College of Dentistry study explores effects of family dynamics on oral health
What does mental health have to do with dental health? Quite a bit, according to Richard Heyman, PhD, and Amy Smith Slep, PhD, psychologists who joined the New York University College of Dentistry (NYUCD) in July 2011.
Jun 6, 2012 - 4:00:00 AM
Appalachian infant death rates point to healthcare deficit
Infant death rates in Appalachia remain significantly higher than much of the rest of the country, and are especially high in the central Appalachian region, according to Penn State health policy researchers.
Jun 6, 2012 - 4:00:00 AM
Minnesota, Mayo Clinic join to advise primary care doctors on pediatric mental health
ROCHESTER, Minn. -- The Minnesota Department of Human Services has entered into a two-year contract with Mayo Clinic to provide expert guidance to pediatricians and other primary care providers who prescribe psychotropic medications for children. The new service is referred to as collaborative psychiatric consultation and is based on pilot projects that improved care and saved money.
Jun 4, 2012 - 4:00:00 AM
Blood test could show women at risk of postnatal depression
Researchers at Warwick Medical School have discovered a way of identifying which women are most at risk of postnatal depression (PND) by checking for specific genetic variants. The findings could lead to the development of a simple, accurate blood test which checks for the likelihood of developing the condition.
May 16, 2012 - 4:00:00 AM
New research expands understanding of psychoactive medication use among children in foster care
Philadelphia -- A few months after the federal Government Accountability Office (GAO) issued a report on the use of psychoactive drugs by children in foster care in five states, a national study from PolicyLab at The Children's Hospital of Philadelphia describes prescription patterns over time in 48 states. The updated findings show the percentage of children in foster care taking antipsychotics--a class of psychoactive drugs associated with serious side effects for children-- continued to climb in the last decade. At the same time, a slight decline was seen in the use of other psychoactive medications, including the percentage of children receiving 3 or more classes of these medications at once (polypharmacy).
Apr 30, 2012 - 4:00:00 AM
New clinical study evaluates first drug to show improvement in subtype of autism
In an important test of one of the first drugs to target core symptoms of autism, researchers at Mount Sinai School of Medicine are undertaking a pilot clinical trial to evaluate insulin-like growth factor (IGF-1) in children who have SHANK3 deficiency (also known as 22q13 Deletion Syndrome or Phelan-McDermid Syndrome), a known cause of autism spectrum disorder (ASD).
Apr 24, 2012 - 4:00:00 AM
Rice University student engineers automate limb lengthening for kids
Another day, another four turns of the screw. That's just a part of life for people, primarily children, undergoing the long and difficult process of distraction osteogenesis, a method to correct bone deformities that leave one limb shorter than the other.
Apr 23, 2012 - 4:00:00 AM
Renowned geneticist R. Rodney Howell receives ACMG Foundation Lifetime Achievement Award
R. Rodney Howell, MD, FACMG, is the recipient of the 2012 American College of Medical Genetics (ACMG) Foundation Lifetime Achievement Award. Dr. Howell is Professor of Pediatrics and Chairman Emeritus at the Miller School of Medicine at the University of Miami.
Apr 3, 2012 - 4:00:00 AM
Test to improve peanut allergy diagnosis
Researchers from Murdoch Childrens Research Institute and the University of Melbourne have identified a new way to accurately test for peanut allergy.
Mar 20, 2012 - 4:00:00 AM
Washington University gets grant to study the human virome in kids
Not all viruses make us sick. But which ones are friends and which ones are foes?
Feb 28, 2012 - 5:00:00 AM
Study compares traits of autism, schizophrenia
A UT Dallas professor is studying the differences between the social impairments found in autism and schizophrenia to help develop better treatments for people with both disorders.
Feb 28, 2012 - 5:00:00 AM
Elusive platelet count and limb development gene discovered
Researchers have identified an elusive gene responsible for Thrombocytopenia with Absent Radii (TAR), a rare inherited blood and skeletal disorder. As a result, this research is now being transformed into a medical test that allows prenatal diagnosis and genetic counselling in affected families.
Feb 26, 2012 - 5:00:00 AM
UC Davis MIND Institute researchers to present on autism at AAAS Annual Meeting in Vancouver
Two UC Davis MIND Institute researchers will lead a symposium on relationships between genetic, epigenetic and environmental influences on the development of autism in children during the American Association for the Advancement of Science (AAAS) Annual Meeting, Feb. 16 -18 in Vancouver, Canada.
Feb 18, 2012 - 5:00:00 AM
Calls for policy changes as lives put at risk by bureaucracy
A European Parliament event to discuss how EU legislation has negatively affected the treatment received by children and adolescents has marked International Childhood Cancer Day - 15th February.
Feb 14, 2012 - 5:00:00 AM
Diagnosing developmental coordination disorder
Children showing difficulty carrying out routine actions, such as getting dressed, playing with particular types of games, drawing, copying from the board in school and even typing at the computer, could be suffering from developmental coordination disorder (DCD), and not necessarily from ADHD or other more familiar disorders, points out Prof. Sara Rosenblum of the Department of Occupational Therapy at the University of Haifa, whose new study set out to shed new light on DCD. In quite a few cases, children are not diagnosed early enough or are given an incorrect diagnosis, which can lead to frustration and a sense of disability. It can even result in a decline that requires psychological therapy, she explains.
Feb 9, 2012 - 5:00:00 AM