 |
|
|
|
|
 |
Last Updated: Jan 12, 2012 - 1:51:02 AM |
Latest Research
:
Cancer
:
Breast Cancer
Interferon-stimulated gene 15 (ISG15), a ubiquitin like protein, is a new therapeutic target for breast cancer
In a study published in the January 2012 issue of Experimental Biology and Medicine, Dr. Shyamal Desai and her co-investigators report that gene knock-down studies demonstrate that elevated ISG15 pathway results in disruption of the cytoskeletal architecture of breast cancer cells. ISG15 also inhibits degradation of cellular proteins involved in cell motility, invasion, and metastasis, promoting breast cancer cell migration
Jan 12, 2012 - 1:44:02 AM
|
Latest Research
Tapping the body's own defenses, researchers look to cutting-edge gene therapy for bladder cancer
CLEVELAND -- Bladder cancer, most frequently caused by smoking and exposure to carcinogens in the workplace, is one of the top 10 most common forms of cancer in menand women in the U.S. More than 70 percent of bladder cancers are diagnosed in stage T1 or less and have not invaded the muscle layer. At these early stages, standard treatment is surgery (transurethral resection) and the burning away of tumors with high energy electricity (fulguration). Many patients also may receive subsequent intravesical chemotherapy because there is often a high-risk for cancer recurrence.
Jan 10, 2012 - 5:00:00 AM
|
Latest Research
Personalized gene therapies may increase survival in brain cancer patients
Personalized prognostic tools and gene-based therapies may improve the survival and quality of life of patients suffering from glioblastoma, an aggressive and deadly form of brain cancer, reports a new University of Illinois study funded by the NIH National Cancer Institute.
Jan 9, 2012 - 5:00:00 AM
|
Latest Research
Estrogen-targeting drug combo may help prevent lung cancer
SAN DIEGO -- A combination of drugs that target estrogen production significantly reduced the number of tobacco carcinogen-induced lung tumors in mice, according to results from a preclinical study.
Jan 9, 2012 - 5:00:00 AM
|
Latest Research
:
Cancer
:
Prostate Cancer
Abiraterone has been approved for men with metastatic prostate cancer that is no longer responsive to therapy with hormones and docetaxel
Abiraterone (trade name: Zytiga®) has been approved since September 2011 for men with metastatic prostate cancer that is no longer responsive to hormone therapy and progresses further during or after therapy with the cytostatic drug docetaxel.
Jan 8, 2012 - 6:23:00 PM
|
Latest Research
:
Cancer
A new sensor to detect lung cancer from exhaled breath
Some illnesses such as lung and stomach cancer or liver diseases which, due to the difficulty of diagnosis, have symptoms that are often confused with routine disorders. Therefore, in most cases, the disease is only detected at an advanced stage. New methods for early detection are being investigated as an urgent need.
Dec 30, 2011 - 11:00:00 PM
|
Latest Research
Northwestern scientist gets mentoring award at White House
CHICAGO --- Teresa Woodruff, the Thomas J. Watkins Professor of Obstetrics and Gynecology at Northwestern University Feinberg School of Medicine, received the prestigious Presidential Award for Excellence in Science, Mathematics and Engineering Mentoring at the White House from President Barack Obama Monday, Dec. 12.
Dec 16, 2011 - 5:00:00 AM
|
Latest Research
RTOG activates study to determine best treatment strategies for patients with glioma brain tumors
Treatment remains controversial for patients diagnosed with a low-risk, low-grade glioma (LGG) brain tumor. These patients have significantly better prognosis than patients diagnosed with more aggressive high-grade glioma, and their clinical care often involves ongoing observation for tumor changes with imaging studies. Because low-risk LGG are slow growing tumors, concerns about the potential adverse effects of early treatment on patients' neurocognitive function (NCF) and quality of life (QOL) may outweigh treatment benefits in patients who are frequently young and highly functional.
Dec 15, 2011 - 5:00:00 AM
|
Latest Research
U.S. Supreme Court petitioned to review AMP, et al. lawsuit on gene patents
WASHINGTON, DC -- The American Civil Liberties Union and the Public Patent Foundation have petitioned the U.S. Supreme Court to hear Association for Molecular Pathology v. U.S. Patent and Trademark Office, a case that challenges the validity of patents on two human genes associated with hereditary breast and ovarian cancer.
Dec 15, 2011 - 5:00:00 AM
|
Latest Research
New test to indicate likely spread or recurrence of breast cancer
A Queensland University of Technology (QUT) PhD student has developed a potential breakthrough test for predicting the likelihood of the spread or return of breast cancer.
Dec 13, 2011 - 5:00:00 AM
|
Latest Research
Circulating tumor cells not linked to survival in newly diagnosed inflammatory breast cancer
SAN ANTONIO, TX -- The presence of circulating tumor cells in the blood appears to have no relationship to survival in women who have just been diagnosed with inflammatory breast cancer, according to new research from Fox Chase Cancer Center. However, the research shows that these stray tumor cells may signal that the disease has spread to other parts of the body, even before imaging reveals any metastases. The results will be presented on Friday, December 9 at the 2011 CTRC-AACR San Antonio Breast Cancer Symposium.
Dec 9, 2011 - 5:00:00 AM
|
Latest Research
Why women quit breast cancer drugs early
CHICAGO --- Why do so many postmenopausal women who are treated for estrogen-sensitive breast cancer quit using drugs that help prevent the disease from recurring?
Dec 9, 2011 - 5:00:00 AM
|
Latest Research
Breast cancer patients face increasing number of imaging visits before surgery
SAN ANTONIO, TX -- Breast cancer patients frequently undergo imaging like mammograms or ultrasounds between their first breast cancer-related doctor visit and surgery to remove the tumor. Evaluations of these scans help physicians understand a person's disease and determine the best course of action. In recent years, however, imaging has increased in dramatic and significant ways, say researchers from Fox Chase Cancer Center. More patients have repeat visits for imaging than they did 20 years ago, and single imaging appointments increasingly include multiple types of imaging.
Dec 9, 2011 - 5:00:00 AM
|
Latest Research
Gene inheritance patterns influence age of diagnosis in BRCA families
LAKE SUCCESS, NY -- Women who inherit the cancer genes BRCA1 or BRCA2 from their paternal lineage may get a diagnosis a decade earlier than those women who carry the cancer genes from their mother and her ancestors, according to a new study by researchers at the North Shore-LIJ Health System's Monter Cancer Center in Lake Success, NY. The findings were reported on Thursday, Dec. 8, at the San Antonio Breast Cancer Symposium.
Dec 9, 2011 - 5:00:00 AM
|
Latest Research
Novel approach to treating breast cancer shows great promise
MAYWOOD, Il. -- In a novel therapeutic approach to treating breast cancer, Loyola University Medical Center researchers are reporting positive results from a clinical trial of a drug that targets tumor stem cells.
Dec 7, 2011 - 5:00:00 AM
|
Latest Research
Study finds side effects, complications, mastectomy more likely after partial breast irradiation
San Antonio, TX - Accelerated partial breast irradiation (APBI) brachytherapy, the localized form of radiation therapy growing increasingly popular as a treatment choice for women with early-stage breast cancer, is associated with higher rate of later mastectomy, increased radiation-related toxicities and post-operative complications, compared to traditional whole breast irradiation (WBI), according to researchers from The University of Texas MD Anderson Cancer Center.
Dec 6, 2011 - 5:00:00 AM
|
Latest Research
Researchers discover patterns of genes associated with timing of breast cancer recurrences
SAN ANTONIO -- An international research team led by Georgetown Lombardi Comprehensive Cancer Center has found biological differences in hormone-receptor positive breast cancer that are linked to the timing of recurrence despite endocrine therapy.
Dec 6, 2011 - 5:00:00 AM
|
Latest Research
University of Kentucky researchers awarded CDC grant to study cancer survival in Appalachia
LEXINGTON, Ky. -- University of Kentucky researchers recently received a $225,000 grant to study the differences in cancer survival in Appalachia.
Dec 5, 2011 - 5:00:00 AM
|
Latest Research
National experts from the John Theurer Cancer Center will present 31 studies at the 2011 ASH Meeting
Hackensack, N.J. (December 1, 2011) - The John Theurer Cancer Center at Hackensack University Medical Center, one of the nation's top 50 best hospitals for cancer, will present research updates and clinical trial results of 31 cutting-edge studies at the 2011 American Society of Hematology (ASH) Annual Meeting in San Diego from December 10-13.
Dec 1, 2011 - 5:00:00 AM
|
Latest Research
:
Cancer
:
Therapy
Taccalonolides from bat plants selectively kill cancer cells
In a new study published this month in the Journal of the American Chemical Society, researchers with The University of Texas Health Science Center at San Antonio have pinpointed the cancer-fighting potential in the bat plant, or Tacca chantrieri.
Nov 22, 2011 - 6:29:24 PM
|
Latest Research
:
Cancer
Derivative of the agent zileuton has proteasome inhibiting properties
Biochemists at the Technische Universitaet Muenchen (TUM) have now identified the lead structure of a new class of drugs that attacks the proteasome in an unusual way. New medication could be developed on the basis of this previously unknown binding mechanism. The scientists report their results in the scientific journal Angewandte Chemie.
Nov 22, 2011 - 5:48:06 PM
|
Latest Research
New service brings power of genomics to patient care
Physicians can now take advantage of a new genetics test -- one of the first of its kind to be offered in the United States -- that can help determine the best treatment for cancer patients.
Nov 22, 2011 - 5:00:00 AM
|
Latest Research
Cancer vaccine impact limited unless drug industry focuses on difficult-to-treat tumors
Drug companies currently developing therapeutic cancer vaccines may be determining the cancers they target based on the number of annual cases, not the number of deaths they cause.
Nov 21, 2011 - 5:00:00 AM
|
Latest Research
George Mason University research gives hope to women with deadliest breast cancer
Women with the deadliest and rarest form of breast cancer now have a chance of treatment where once their options were severely limited, thanks to a new discovery by George Mason University researchers.
Nov 14, 2011 - 5:00:00 AM
|
Latest Research
Risk of contracting diabetes to increase in world of 7 billion people
World citizen number 7 billion is less likely to die from infectious diseases like measles or even AIDS, and more likely to contract diabetes or other non-communicable diseases (NCDs), as they are now the leading causes of deaths globally.
Nov 14, 2011 - 5:00:00 AM
|
Latest Research
Scientists identify genes that may signal long life in naked mole-rats
Scientists at the University of Liverpool have identified high levels of a number of genes in the naked mole-rat that may suggest why they live longer than other rodents and demonstrate resistance to age-related diseases.
Nov 3, 2011 - 4:00:00 AM
|
Latest Research
Scientists prove regular aspirin intake halves cancer risk
Scientists including those from Queen's University have discovered that taking regular aspirin halves the risk of developing hereditary cancers.
Oct 28, 2011 - 4:00:00 AM
|
Latest Research
Controlling gene expression to halt cancer growth
NUT midline carcinoma (NMC) is a cancer without a cure, and one that affects all age groups. NMC is a rapid-growth disease with an average survival time of four and a half months after diagnosis, making the development of clinical trials for potential therapies or cures for this cancer difficult, to say the least.
Oct 28, 2011 - 4:00:00 AM
|
Latest Research
NYU College of Nursing receives 450 thousand dollar NIH grant to research post-breast cancer lymphedema
New York University College of Nursing (NYUCN) received a two-year, $452,218.00 grant from the national Institutes of Health (NIH) to research Proinflammatory Biomarkers and Post-Breast Cancer Lymphedema. Post-breast cancer lymphedema (LE), a syndrome of abnormal swelling and multiple distressing symptoms, is caused by injuries to the lymphatic system from cancer treatment. As advances in cancer treatment lengthen survival, LE has emerged as a high-impact long-term morbidity that profoundly impairs survivors' quality of life.
Oct 27, 2011 - 4:00:00 AM
|
Latest Research
:
Cancer
CK1 protein in cancer cells identified as possible future therapeutic target
Researchers from the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, have identified a cell cycle-regulated mechanism behind the transformation of normal cells into cancerous cells. The study shows the significant role that protein networks can play in a cell leading to the development of cancer.
Oct 24, 2011 - 4:00:00 AM
|
Latest Research
Association of quantity of alcohol and frequency of consumption with cancer mortality
A paper from the National Institutes of Health in the United States has evaluated the separate and combined effects of the frequency of alcohol consumption and the average quantity of alcohol drunk per occasion and how that relates to mortality risk from individual cancers as well as all cancers. The analysis is based on repeated administrations of the National Health Interview Survey in the US, assessing more than 300,000 subjects who suffered over 8,000 deaths from cancer. The research reports on total cancer deaths and deaths from lung, colorectal, prostate, and breast cancers.
Oct 20, 2011 - 4:00:00 AM
|
Latest Research
ASE-EAE to issue guidelines for the echocardiographic evaluation of cancer patients
Considering that the early detection of cardio toxicity is a critical issue for patients undergoing chemotherapy, the ASE and the EAE have come together to write guidelines which will highlight the technical advantages of echocardiography in identifying cardio toxicity early, explained Prof Juan Carlos Plana, Co-Director of the Cardio-oncology Center, Cleveland Clinic, from the ASE. This would help select patients who would benefit from cardio protective regimens, so that heart failure does not become an obstacle to the oncologist during therapy, and to the patient during his/her survival.
Oct 20, 2011 - 4:00:00 AM
|
Latest Research
Terry Fox Research Institute aims to change diagnosis and management of ovarian cancer worldwide
MONTREAL, QUE. -- Women throughout the world will benefit from a new, pan-Canadian Terry Fox Research Institute (TFRI) initiative that aims to change the way in which ovarian cancer is diagnosed and managed. TFRI and the Canadian Partnership Against Cancer are providing a total of $5-million in funding for a five-year, multi-site Ovarian Cancer Pan-Canadian Program called COEUR. The program will identify new biomarkers to predict and treat this relatively rare but deadly form of cancer, which will result in the use and application of current and new drugs more effectively for patients.
Oct 13, 2011 - 4:00:00 AM
|
Latest Research
$9.55 million NCI grant targets the resistance of advanced prostate cancer
When caught in its early stages, prostate cancer is treatable in most cases. But once it reaches a critical threshold, the disease becomes largely resistant to current treatments. The National Cancer Institute (NCI) recently awarded a team of cancer biologists $9.55 million over five years to define the molecular changes that occur as prostate cancer progresses to the therapy-resistant state.
Oct 11, 2011 - 4:00:00 AM
|
Latest Research
Case Western Reserve receives prestigious $5.4 million grant to study esophageal cancer
Case Western Reserve University School of Medicine and the Case Comprehensive Cancer Center are proud to announce the receipt of a highly competitive $5.4 million grant to study genetic determinants of Barrett's esophagus and esophageal adenocarcinoma. This five-year award from the National Cancer Institute will support the Barrett's Esophagus Translational Research Network (BETRNet), which consists of multiple centers collaborating to develop an understanding of the basis of Barrett's esophagus and its conversion to esophageal carcinoma. Researchers will also work to determine the role genetics and environmental factors play in the development and progression of these diseases, with the ultimate goal of reducing the mortality associated with this deadly cancer.
Oct 10, 2011 - 4:00:00 AM
|
Latest Research
Almost half of cancer survivors have ill health in later years
Forty-five per cent of cancer survivors in Northern Ireland suffer from physical and mental health problems years after their treatment has finished, according to new research from Macmillan Cancer Support and Queen's University Belfast.
Oct 10, 2011 - 4:00:00 AM
|
Latest Research
New research shows PET imaging effective in predicting lung cancer outcomes
Advanced imaging with Positron Emission Tomography (PET) scans shows great promise in predicting which patients with inoperable lung cancer have more aggressive tumors and need additional treatment following standard chemotherapy/radiation therapy, according to new research.
Oct 5, 2011 - 4:00:00 AM
|
Latest Research
Survey reveals reasons doctors avoid online error-reporting tools
Too busy, and too complicated. These are the typical excuses one might expect when medical professionals are asked why they fail to use online error-reporting systems designed to improve patient safety and the quality of care. But, Johns Hopkins investigators found instead that the most common reason among radiation oncologists was fear of getting into trouble and embarrassment.
Oct 4, 2011 - 4:00:00 AM
|
Latest Research
Liver cancer incidence lower in patients with nonalcoholic fatty liver disease than hepatitis C
Patients with non-alcoholic fatty liver disease (NAFLD) with advanced fibrosis or cirrhosis have a lower incidence of liver-related complications and hepatocellular carcinoma (HCC) than patients infected with hepatitis C virus (HCV), according to the prospective study published in the October issue of Hepatology, a journal of the American Association for the Study of Liver Diseases. Patients with both NAFLD and HCV had similar mortality rates.
Sep 27, 2011 - 4:00:00 AM
|
Latest Research
Newly identified DNA repair defect linked to increased risk of leukemia relapse
A newly identified defect in a DNA repair system might leave some young leukemia patients less likely to benefit from a key chemotherapy drug, possibly putting them at greater risk of relapse. The problem was identified in a study led by St. Jude Children's Research Hospital scientists.
Sep 26, 2011 - 4:00:00 AM
|
Latest Research
IMRT has less harmful rectal side effects than 3D-CRT for prostate cancer patients
Men with localized prostate cancer treated with a newer technology, intensity modulated radiation therapy (IMRT), have more than a quarter (26 percent) fewer late bowel and rectal side effects and a statistically improved lower dose of radiation to the bladder and rectum, compared to those who undergo 3D-CRT, according to a randomized study presented at the plenary session October 3, 2011, at the 53rd Annual Meeting of the American Society for Radiation Oncology (ASTRO).
Sep 26, 2011 - 4:00:00 AM
|
Latest Research
Shorter radiation course for prostate cancer is effective in long-term follow-up
A shorter course of radiation treatment that delivers higher doses of radiation per day in fewer days (hypofractionation) is as effective in decreasing intermediate to high-risk prostate cancer from returning as conventional radiation therapy at five years after treatment, according to a randomized trial presented at the plenary session, October 3, 2011, at the 53rdAnnual Meeting of the American Society for Radiation Oncology (ASTRO).
Sep 26, 2011 - 4:00:00 AM
|
Latest Research
Chemo plus radiation before surgery increases tumor response for rectal cancer
Rectal cancer patients who use a new combination of the chemotherapy, Capecitabine, together with five weeks of radiation (50 Gy) before surgery have an 88 percent chance of surviving the cancer three years after treatment, according to randomized trial presented at the plenary session, October 3, 2011, at the 53rd Annual Meeting of the American Society for Radiation Oncology (ASTRO).
Sep 26, 2011 - 4:00:00 AM
|
Latest Research
High blood pressure is linked to increased risk of developing or dying from cancer
Stockholm, Sweden: Raised blood pressure is linked to a higher risk of developing cancer or dying from the disease according to the findings of the largest study to date to investigate the association between the two conditions.
Sep 26, 2011 - 4:00:00 AM
|
Latest Research
Researchers uncover gene associated with blood cancers
A genomic study of chronic blood cancer - a precursor to leukaemia - has discovered gene mutations that could enable diagnosis using only a blood test, avoiding the need for an invasive and painful bone marrow biopsy.
Sep 26, 2011 - 4:00:00 AM
|
Latest Research
Chemotherapy during pregnancy does not seem to cause developmental problems in children
Stockholm, Sweden: Children born after their mothers were treated with chemotherapy during pregnancy appear to be unaffected by the experience in terms of the development of their mental processes and the normal functioning of their hearts, according to new research presented at the 2011 European Multidisciplinary Cancer Congress [1].
Sep 26, 2011 - 4:00:00 AM
|
Latest Research
Bone-strengthening drug gives pain relief in prostate cancer bone metastases
Stockholm, Sweden: Many prostate cancer patients develop bone metastases, and controlling the pain these cause can be difficult. Now the first large randomised Phase III trial of a bisphosphonate drug in these patients has shown that a single dose of the drug is as good for pain relief as single dose radiotherapy, the standard treatment for bone metastases. Results of the trial were presented today (Sunday) at the 2011 European Multidisciplinary Cancer Congress [1].
Sep 25, 2011 - 4:00:00 AM
|
Latest Research
Zoledronic acid reduces the recurrence of breast cancer in post-menopausal women
Stockholm, Sweden: A trial investigating the use of zoledronic acid to aid chemotherapy for breast cancer has found a significant benefit for post-menopausal women, according to results presented at the 2011 European Multidisciplinary Cancer Congress [1] today (Sunday). Researchers think it could be the key for a greater understanding of the mechanisms of breast cancer recurrence as well as offering new options for patient care.
Sep 25, 2011 - 4:00:00 AM
|
Latest Research
Aromatase inhibitor letrozole guards against breast cancer relapse for up to 8 years
Stockholm, Sweden: Results from the longest-running trial comparing tamoxifen with the aromatase inhibitor letrozole show unequivocally that letrozole has withstood the test of time and continues to prevent breast cancer recurrences and reduce the risk of death in post-menopausal women with hormone receptor-positive early breast cancer.
Sep 25, 2011 - 4:00:00 AM
|
Latest Research
Infusing chemotherapy into the liver gives extra months of disease-free life in melanoma patients
Stockholm, Sweden: Melanoma of the eye (ocular or uveal melanoma) frequently spreads to the liver and, once this has happened, there is no effective treatment and patients die within an average of two to four months. Only about one in ten patients live for a year. Now, final results from a phase III study have demonstrated that a new treatment significantly extends the time patients can live without the disease progressing.
Sep 23, 2011 - 4:00:00 AM
|
|
|
|
|
| Health |
Best way to boost adult immunizations is through office-based action, study finds
|
'Pep talk' can revive immune cells exhausted by chronic viral infection
|
Burning more sugar drives super athleticism
|
Research aims to prevent obesity by reaching parents, young children through child care
|
AMD-like lesions delayed in mice fed lower glycemic index diet
|
Low vitamin C levels may raise heart failure patients' risk
|
Sugar-sweetened beverages may increase cardiovascular risk in women
|
Study finds shifting disease burden following universal Hib vaccination
|
UT study: Climate change affects ants and biodiversity
|
Dirt prevents allergy
|
| | Healthcare |
Fitness club memberships help insurance plans to enrol healthier patients
|
Anxiety disorders mount since credit crunch
|
Doctors diagnose patients within moments of meeting
|
Physician-defined patient complexity differs from current diagnosis-based measures
|
Free health screening for school children Nov 14
|
Systematic bias in the assessment of UK doctors
|
White children far more likely to receive CT scans than Hispanic, African-American children
|
Suspected brain disease kills 51 kids in Bihar
|
New rules for bio-medical waste management in India
|
Delhi hospitals lacking in emergency protocols
|
| | Latest Research |
New device performs better than old for removing blood clots
|
Gene related to fat preferences in humans found
|
Cardiovascular Nursing Spring Meeting
|
The effect of occasional binge drinking on heart disease and mortality among moderate drinkers
|
ORNL, partners earn FLC honor for cookstove technology
|
Clot-busting drugs appear safe for treating 'wake-up' stroke patients
|
Infections in childhood linked to high risk of ischemic stroke
|
Penn State scientists elected to American Geophysical Union
|
Wayne State University project aims to reduce HIV, AIDS among African-Americans
|
Scientists help define structure of exoplanets
|
| | Medical News |
Women delivers baby near lift in Noida hospital
|
Obesity on rise in school children: Study
|
Over 10,000 dengue cases in India this year
|
NRI doctors demands removal of 'tainted' medical council members
|
Watch out for sexually transmitted 'superbug': Expert
|
Panel stresses on infection control in hospitals
|
Healthcare cost up 22 times in rural areas, shows study
|
Superbug exists, but nothing alarming: Walia
|
No power problem at AIIMS: Official
|
40 percent Indians embarrassed to ask for contraceptives
|
| | Special Topics |
Behold India's unfolding democratic revolution
|
Chinese woman cuts open her belly to save surgery cost
|
Improved Sense of Smell Produced Smarter Mammals
|
Two-year-old world's first to have extra DNA strand
|
172,155 kidney stones removed from one patient!
|
'Primodial Soup' theory for origin of life rejected in paper
|
Human species could have killed Neanderthal man
|
History, geography also seem to shape our genome
|
3,000 Kerala medical students to attend inter-college meet
|
Tamil Nadu seeks to control deemed universities
|
|
|
