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Last Updated: Apr 14, 2008 - 2:04:51 PM |
Latest Research
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Cancer
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Liver Cancer
Sunitinib slows tumor growth and metastasis in hepatocellular carcinoma
Treatment with sunitinib slows tumor growth and reduces the risk of metastasis in patients with hepatocellular carcinoma, an aggressive cancer of the liver, researchers report.
Apr 14, 2008 - 2:01:16 PM
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Latest Research
Calorie restriction limits and obesity fuels development of epithelial cancers
SAN DIEGO - A restricted-calorie diet inhibited the development of precancerous growths in a two-step model of skin cancer, reducing the activation of two signaling pathways known to contribute to cancer growth and development, researchers at The University of Texas M. D. Anderson Cancer Center report today at the American Association for Cancer Research annual meeting.
Apr 14, 2008 - 4:00:00 AM
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Latest Research
Mouth may tell the tale of lung damage caused by smoking
SAN DIEGO - Cells lining the mouth reflect the molecular damage that smoking does to the lining of the lungs, researchers at The University of Texas M. D. Anderson Cancer Center report today at the annual meeting of the American Association for Cancer Research.
Apr 13, 2008 - 4:00:00 AM
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Latest Research
In lab study, researchers find molecule that disrupts Ewing's sarcoma oncogene
Researchers at Georgetown University Medical Center have found a small molecule they say can block the action of the oncogene that causes Ewing's sarcoma, a rare cancer found in children and young adults. If further studies continue to prove beneficial, they say the novel agent could be the first targeted therapy to treat the disease, which can produce tumors anywhere in the body.
Apr 13, 2008 - 4:00:00 AM
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Latest Research
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Cancer
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Breast Cancer
Ultrasound-guided fine needle aspiration (USFNA) of the lymph nodes is -a useful preoperative staging for breast cancer
Ultrasound-guided fine needle aspiration (USFNA) of the lymph nodes is a safe, useful, and minimally invasive procedure for diagnosing metastatic disease in patients who are undergoing preoperative staging for breast cancer, according to a recent study conducted by researchers at the Rhode Island Hospital/Warren Alpert Medical School of Brown University in Providence, RI.
Apr 12, 2008 - 10:09:03 AM
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Latest Research
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Cancer
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Breast Cancer
Screening mammography in elderly patients beneficial
Although guidelines keep changing regarding screening mammography in elderly patients, those older than 70 years old continue to benefit from this exam, showing that with frequent mammograms breast cancers can be found sooner, according to a recent study conducted by researchers at Jacobi Medical Center and Albert Einstein College of Medicine, in Bronx, NY.
Apr 12, 2008 - 4:00:00 AM
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Latest Research
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Radiology
Indian American develops tool to image tumours
New York, April 1 - A team of researchers led by Indian American Sanjiv Gambhir has developed a new type of imaging system capable of picturing tumours to a precision of a trillionth of a meter.
Apr 11, 2008 - 10:30:58 AM
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Latest Research
Needle-size device created to track tumors, radiation dose
WEST LAFAYETTE, Ind. - Engineers at Purdue University are creating a wireless device designed to be injected into tumors to tell doctors the precise dose of radiation received and locate the exact position of tumors during treatment.
Apr 8, 2008 - 4:00:00 AM
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Latest Research
Combination therapy improves survival time for patients with more advanced liver cancer
Combining a type of chemotherapy with radiothermal therapy resulted in longer survival time for patients with advanced liver cancer, compared to receiving the therapies alone, according to a study in the April 9 issue of JAMA.
Apr 8, 2008 - 4:00:00 AM
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Latest Research
Blood pressure enzyme can have tumor-sensing role
By increasing production of a blood pressure-regulating enzyme in mice, researchers have found they can enhance the mouse immune system's ability to sense tumor growth.
Apr 7, 2008 - 4:00:00 AM
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Latest Research
Researchers learn how signaling molecule orchestrates breast cancer's spread
NEW YORK, April 3, 2008 -- A study led by researchers at Memorial Sloan-Kettering Cancer Center (MSKCC) has uncovered how breast tumors use a particular type of molecule to promote metastasis -- the spread of cancer cells. Metastasis is the cause of approximately 90 percent of all cancer-related deaths. The study is published in the April 4, 2008, issue of Cell.
Apr 3, 2008 - 4:00:00 AM
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Latest Research
Enzyme complex could be key to new cancer treatments
Penn State scientists are the first to observe in living cells a key step in the creation of adenine and guanine, two of the four building blocks that comprise DNA. Also called purines, the two building blocks are essential for cell replication. The findings, which will be published in the 4 April 2008 issue of the journal Science, could lead to new cancer treatments that prevent cancer cells from replicating by interfering with their abilities to make purines.
Apr 3, 2008 - 4:00:00 AM
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Latest Research
Genetic variations raise lung cancer risk for smokers and ex-smokers
HOUSTON - Two common inherited genetic variations are associated with increased risk of lung cancer for smokers and former smokers, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports April 2 in the online edition of Nature Genetics.
Apr 2, 2008 - 4:00:00 AM
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Latest Research
Nano-sized technology has super-sized effect on tumors
Anyone facing chemotherapy would welcome an advance promising to dramatically reduce their dose of these often harsh drugs. Using nanotechnology, researchers at Washington University School of Medicine in St. Louis have taken a step closer to that goal.
Apr 2, 2008 - 4:00:00 AM
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Latest Research
Families of children with cancer support human tissue research, study finds
Families of children with cancer support research using tissue samples left over after operations, a new study has found.
Apr 1, 2008 - 4:00:00 AM
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Latest Research
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Gynaecology
Hormone replacement therapy linked to cancer recurrence
London, March 26 - Hormone replacement therapy - for pre and post menopausal women increases the chances of recurrence in breast cancer survivors, according to a study.
Mar 26, 2008 - 10:32:07 AM
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Latest Research
Mounting evidence shows red wine antioxidant kills cancer
Rochester researchers showed for the first time that a natural antioxidant found in grape skins and red wine can help destroy pancreatic cancer cells by reaching to the cell's core energy source, or mitochondria, and crippling its function. The study is published in the March edition of the journal, Advances in Experimental Medicine and Biology.
Mar 25, 2008 - 4:00:00 AM
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Latest Research
Multi-institutional study identifies new form of inherited risk of cancer
NEW YORK (March 25, 2008) -- Like the subtext of a novel, the human genome sequence harbors more information than appears just in its letters of A, C, T and G. Since DNA is a data-packed molecule passed from generation to generation, comparing genome sequences among individuals also holds clues to ancestry.
Mar 25, 2008 - 4:00:00 AM
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Latest Research
Targeting aggressive breast cancers by putting them to sleep
It is well established that Id1, a gene normally produced only in embryonic development, is reactivated in many 'solid' cancers, or carcinomas.
Mar 24, 2008 - 4:00:00 AM
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Latest Research
Stanford researchers unmask proteins in telomerase, a substance that enables cancer
STANFORD, Calif. - One of the more intriguing workhorses of the cell, a protein conglomerate called telomerase, has in its short history been implicated in some critical areas of medicine including cancer, aging and keeping stem cells healthy. With such a resume, telomerase has been the subject of avid interest by basic scientists and pharmaceutical companies alike, so you'd think at the very least people would know what it is.
Mar 20, 2008 - 4:00:00 AM
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Latest Research
Stanford researchers unmask proteins in telomerase, a substance that enables cancer
STANFORD, Calif. - One of the more intriguing workhorses of the cell, a protein conglomerate called telomerase, has in its short history been implicated in some critical areas of medicine including cancer, aging and keeping stem cells healthy. With such a resume, telomerase has been the subject of avid interest by basic scientists and pharmaceutical companies alike, so you'd think at the very least people would know what it is.
Mar 20, 2008 - 4:00:00 AM
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Latest Research
Neuronal regulators offer potential targets for cancer
Boston, Mass. (March 19, 2008) -- Being too brainy can be a bad thing in a junior high cafeteria, where the social hierarchy favors other traits. Braininess also causes problems for cells. When a breast cell begins making the proteins normally produced in neurons, for example, it can acquire cancerous properties.
Mar 19, 2008 - 4:00:00 AM
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Latest Research
Researchers develop method to rapidly ID optimal drug cocktails
UCLA researchers have developed a feedback control scheme that can search for the most effective drug combinations to treat a variety of conditions, including cancers and infections. The discovery could play a significant role in facilitating new clinical drug-cocktail trials.
Mar 17, 2008 - 4:00:00 AM
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Latest Research
Cancer detected earlier, faster, with new medical imaging, Stanford study finds
STANFORD, Calif. - Doctors may one day be able to detect early stages of colon cancer without a biopsy, using a new technique developed by researchers at the Stanford University School of Medicine.
Mar 16, 2008 - 4:00:00 AM
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Latest Research
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Cancer
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Breast Cancer
Obesity causes breast cancer to be aggressive
Women with breast cancer have more aggressive disease and lower survival rates if they are overweight or obese, according to findings published in the March 15 issue of Clinical Cancer Research, a journal of the American Association for Cancer Research.
Mar 14, 2008 - 11:03:17 AM
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Latest Research
Body Mass Index may serve as prognostic tool for advanced, aggressive breast cancers
HOUSTON - Body Mass Index (BMI), the measure of a person's fat based on their height and weight, may be an effective prognostic tool for specific types of breast cancer, according to research from The University of Texas M. D. Anderson Cancer Center.
Mar 14, 2008 - 4:00:00 AM
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Latest Research
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Cancer
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Pancreatic Cancer
Multimodality approach beneficial even in advanced cancers
The article published in volume 14 issue 6 of World Journal of Gastroenterology reports on one patient who presented to Dr Cosimo Sperti of University of Padua, Padova, Italy, in 2001 after an exploratory laparotomy performed in another hospital for an unresectable pancreatic cystic mass that had infiltrated the portal vein
Mar 13, 2008 - 5:50:13 AM
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Latest Research
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Cancer
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Liver Cancer
Combined stenting and photodynamic therapy may improve survival rates in liver cancer
A combined therapeutic approach of stenting and photodynamic therapy may improve survival rates for patients suffering from advanced liver bile duct cancer, according to a study published this month in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association (AGA) Institute.
Mar 11, 2008 - 3:40:58 PM
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Latest Research
USC researchers find benefit for lymphoma patients in combined PET-CT scanning
Los Angeles, March 12 --Combined positron emission tomography (PET) and computed tomography (CT) imaging of lymphoma patients is a more effective method to evaluate response to radiation therapy, and may help patients avoid unnecessary follow-up treatments, a study by researchers at the University of Southern California (USC) suggests.
Mar 11, 2008 - 4:00:00 AM
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Latest Research
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Cancer
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Breast Cancer
Why tumour cells are herceptin resistant
UC Davis Cancer Center researchers have discovered a likely reason why some tumor cells are inherently resistant — or become resistant over time — to the popular breast cancer drug trastuzumab, commonly referred to by the brand name Herceptin.
Mar 8, 2008 - 7:47:45 AM
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Latest Research
Lombardi Cancer Center's Toretsky awarded prestigious Burroughs Wellcome Fund Award
Jeffrey A. Toretsky, M.D., a pediatric oncology physician and researcher at Georgetown University's Lombardi Comprehensive Cancer Center has received a prestigious Clinical Scientist Award in Translational Research from the Burroughs Wellcome Fund (BWF). The $750,000 award, one of only 13 given in 2008, is intended to support established, independent physician-scientists who are dedicated to translational research -- the two-way transfer between laboratory research and patient treatment -- and mentoring physician-scientist trainees.
Mar 7, 2008 - 5:00:00 AM
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Latest Research
PET/CT planning beneficial for head and neck cancer patients
Using a combination of positron emission tomography (PET) and computed tomography for radiation therapy treatment planning in head and neck carcinoma patients provides for excellent, local and regional disease control when compared to CT alone, according to a study in the March 1 issue of the International Journal for Radiation Oncology*Biology*Physics, the official journal of the American Society for Therapeutic Radiology and Oncology.
Mar 4, 2008 - 5:00:00 AM
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Latest Research
WHI follow-up study: Risks of long-term hormone therapy continue to outweigh benefits
New results from the Women's Health Initiative (WHI) confirm that the health risks of long-term use of combination (estrogen plus progestin) hormone therapy in healthy, postmenopausal women persist even a few years after stopping the drugs and clearly outweigh the benefits. Researchers report that about three years after women stopped taking combination hormone therapy, many of the health effects of hormones such as increased risk of heart disease are diminished, but overall risks, including risks of stroke, blood clots, and cancer, remain high. The WHI is sponsored by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH).
Mar 4, 2008 - 5:00:00 AM
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Latest Research
Short RNA strand helps exposed skin cells protect body from bacteria, dehydration and even cancer
Every minute, 30,000 of our outermost skin cells die so that we can live. When they do, new cells migrate from the inner layer of the skin to the surface of it, where they form a tough protective barrier. In a series of elegant experiments in mice, researchers at Rockefeller University have now discovered a tiny RNA molecule that helps create this barrier. The results not only yield new insight into how skin first evolved, but also suggest how healthy cells can turn cancerous.
Mar 2, 2008 - 5:00:00 AM
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Latest Research
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Cancer
Arsenic likely to be powerful imaging agent in detecting cancers
Arsenic linked to a drug that binds to the blood vessels of cancerous tumors provides a powerful imaging agent that could one day allow physicians to detect hard-to-find tumors and more closely monitor cancer’s response to therapy, researchers at UT Southwestern Medical Center have found.
Mar 2, 2008 - 3:33:01 AM
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Latest Research
Mouse model tightly matches pediatric tumor syndrome, will speed drug hunt
Frustrated by the slow pace of new drug development for a condition that causes pediatric brain tumors, a neurologist at Washington University School of Medicine in St. Louis decided to try to fine-tune the animal models used to test new drugs.
Mar 1, 2008 - 5:00:00 AM
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Latest Research
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Cancer
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Breast Cancer
Which is better-Lapatinib and/or Trastuzumab? International study to answer this
Two targeted medications designed to treat an aggressive form of breast cancer are being tested in a new study involving 8,000 participants in 50 countries across six continents -- a clinical trial that investigators hope will provide a new model for global cancer research. This trial, dubbed ALTTO (Adjuvant Lapatinib and/or Trastuzumab Treatment Optimization study), will be one of the first global initiatives in which two large, academic breast cancer research networks covering different parts of the world have jointly developed a study in which all care and data collection are standardized, regardless of where patients are treated.
Mar 1, 2008 - 3:36:33 AM
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Latest Research
Gene expression differences between Europeans and Africans affect response to drugs, infections
Differences in gene expression levels between people of European versus African ancestry can affect how each group responds to certain drugs or fights off specific infections, report researchers from the University of Chicago Medical Center and the Expression Research Laboratory at Affymetrix Inc. of Santa Clara, CA.
Feb 28, 2008 - 5:00:00 AM
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Latest Research
Grant to study if early BPA exposure leads to late prostate cancer
Does exposure of baby boys -- in utero or in infancy -- to bisphenol A, a man-made chemical which mimics natural estrogens, predispose them to prostate cancer later in life?
Feb 20, 2008 - 5:00:00 AM
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Latest Research
Scientists using laser light to detect potential diseases via breath samples, says new study
By blasting a person's breath with laser light, scientists from the National Institute of Standards and Technology and the University of Colorado at Boulder have shown that they can detect molecules that may be markers for diseases like asthma or cancer.
Feb 18, 2008 - 5:00:00 AM
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Latest Research
Vaccine/antibody therapy effective, milder side effects in melanoma and ovarian cancer
BOSTON--One of the shortcomings of a therapy that uses millions of identical antibodies to boost the immune system's attack on cancer cells is that many patients whose tumors recede in response to the treatment also experience serious inflammatory problems, such as severe diarrhea and rashes. In a new study, a team led by Dana-Farber Cancer Institute researchers shows that giving periodic infusions of such monoclonal antibodies to patients who have received a widely used cancer vaccine unleashes a strong immune response to tumors, with less-harsh side effects.
Feb 18, 2008 - 5:00:00 AM
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Latest Research
Major study links insurance status to advanced stage in multiple cancers
ATLANTA -- A new American Cancer Society study of twelve types of cancer among more than 3.5 million cancer patients finds uninsured patients were significantly more likely to present with advanced stage cancer compared to patients with private insurance. The study, which appears in the March issue of The Lancet Oncology, is the first to use national data to investigate insurance status and stage of diagnosis for a large number of cancer sites. It finds the strongest association between insurance status and advanced cancer was for cancers that can be detected early by screening or evaluation of symptoms.
Feb 17, 2008 - 5:00:00 AM
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Latest Research
oxidative stress may be the culprit underlying aging , and is associated with many diseases .
ANN ARBOR, Mich.---Oxygen, although essential for human life, can turn into an aggressive chemical that is outright toxic to important molecules inside our cells. This oxidative stress is associated with many diseases, such as Alzheimer's, heart disease and cancer, and has been suggested to be the culprit underlying aging.
Feb 16, 2008 - 1:30:00 AM
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Latest Research
Review of online breast cancer information encourages healthy skepticism for consumers
HOUSTON - In an extended analysis of Web pages dedicated to disseminating breast cancer information, researchers at two University of Texas institutions in the Houston have determined that while most breast cancer data found online was accurate, one in 20 breast cancer Web pages featured inaccuracies and sites displaying complementary and alternative medicine were 15 times more likely to contain false or misleading health information.
Feb 11, 2008 - 5:00:00 AM
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Latest Research
Genome-wide survey nets key melanoma gene
One might call it a tale of two melanocytes. Given the same genetic mutation, why does one melanocyte shut down growth and become a relatively benign mole, while another rages out of control and develops into deadly melanoma
Feb 8, 2008 - 3:40:00 AM
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Latest Research
Natural secretion marks difference between mole and melanoma
A protein naturally produced and secreted by the body can make the difference between your average mole and melanoma, which killed more than 8,000 people in the United States last year, reveals a new study in the February 8 issue of the journal Cell, a publication of Cell Press.
Feb 8, 2008 - 3:30:00 AM
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Latest Research
Transparent fish to make human biology clearer
Zebrafish are genetically similar to humans and are good models for human biology and disease. Now, researchers at Children's Hospital Boston have created a zebrafish that is transparent throughout its life. The new fish allows scientists to directly view its internal organs, and observe processes like tumor metastasis and blood production after bone-marrow transplant in a living organism.
Feb 6, 2008 - 5:00:00 AM
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Latest Research
Breast cancer diagnosis comes late for women in gentrifying neighborhoods
Women who live in Chicago's gentrifying neighborhoods are more apt to receive a late diagnosis of breast cancer than women who live in poverty-stricken neighborhoods, University of Illinois at Chicago researchers have found.
Feb 5, 2008 - 11:30:00 PM
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Latest Research
New, noninvasive prostate cancer test beats PSA in detecting prostate cancer
An experimental biomarker test developed by researchers at the University of Michigan more accurately detects prostate cancer than any other screening method currently in use, according to a study published in the February 1 issue of Cancer Research, a journal of the American Association for Cancer Research.
Feb 5, 2008 - 10:25:00 PM
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Latest Research
Anemia treatment may be a double-edged sword
Erythropoietin has so far been known to doctors as a hormone that boosts red-blood-cell production. Now, a mouse study led by Lois Smith, MD, PhD, an ophthalmologist at Children's Hospital Boston, shows it also keeps blood vessels alive and growing in the eye. The findings not only add a new function to the hormone, but also give doctors a reason to pause before prescribing it to patients with diseases affected by abnormal blood-vessel growth, such as retinopathy and cancer.
Jan 30, 2008 - 5:00:00 AM
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