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Latest Research : Cancer
  Last Updated: Jan 31, 2010 - 3:47:51 AM

Latest Research
SDSC joins other UC San Diego departments, LLNL in oncology collaboration
Researchers from the San Diego Supercomputer Center (SDSC) at UC San Diego have joined forces with the Department of Radiation Oncology in the university's School of Medicine, its Department of Mathematics, and the Lawrence Livermore National Laboratory (LLNL) in a three-year, $1.5 million project to pursue novel applications of high-performance computing (HPC) in radiotherapy.
Jan 31, 2010 - 4:59:12 AM

Latest Research
Case Western Reserve receives $2.8 million to further breast cancer research
Case Western Reserve University School of Medicine has been awarded six Department of Defense (DOD) Congressionally Directed Medical Research Programs (CDMRP) grants for innovative medical research. The grants, totaling nearly $2.8 million, will advance research in the field of breast cancer.
Jan 27, 2010 - 4:59:36 AM

Latest Research
Texas invests $4.5 million in cancer research at UT Health Science Center at Houston
Texas plans to invest $3 billion in cancer research over the next 10 years and six scientists at The University of Texas Health Science Center at Houston are among the first to receive grants.
Jan 26, 2010 - 4:59:36 AM

Latest Research
Novel personalized medicine trial launched for metastatic colorectal cancer
FAIRFAX, Va. -- Imagine if treatments for disease could be based not on a patient's diagnosis but instead on the characteristics of their tissue. By identifying and decoding the cryptic messages hidden deep inside the human proteome, scientists and physicians who study personalized medicine are seeking more effective treatments and disease management for patients.
Jan 15, 2010 - 4:59:36 AM

Latest Research : Cancer : Prostate Cancer
Intermittent Androgen Suppression Therapy in the Treatment of Prostate Cancer
Intermittent androgen suppression therapy seems to be as effective as continuous androgen deprivation while showing tolerability and quality of life advantages, according to a study published in the January issue of European Urology, the official journal of the European Association of Urology.
Jan 5, 2010 - 1:56:42 PM

Latest Research : Cancer : Breast Cancer
Acupuncture has added benefits in breast cancer patients
Not only is acupuncture as effective as drug therapy at reducing hot flushes in breast cancer patients, it has the added benefit of potentially increasing a woman's sex drive and improving her sense of well-being, according to a Henry Ford Hospital study.
Dec 30, 2009 - 1:36:51 PM

Latest Research : Cancer : Prostate Cancer
Inhibition of TNF-receptor associated protein-1possible treatment for prostatic cancer
Current research suggests that TNF-receptor associated protein-1 (TRAP-1) may prevent cancer cell death. The related report by Leav et al, "Cytoprotective Mitochondrial Chaperone TRAP-1 as a Novel Molecular Target in Localized and Metastatic Prostate Cancer," appears in the January 2010 issue of the American Journal of Pathology.
Dec 30, 2009 - 1:28:05 PM

Latest Research : Cancer : Liver Cancer
Chlorophyll limits the absorption of the carcinogen aflatoxin
A new study has found that chlorophyll and its derivative chlorophyllin are effective in limiting the absorption of aflatoxin in humans. Aflatoxin is produced by a fungus that is a contaminant of grains including corn, peanuts and soybeans; it is known to cause liver cancer.
Dec 30, 2009 - 12:52:05 PM

Latest Research
Chicago Cancer Genome Project studies genetics of 1,000 tumors
No two tumors are alike, but analyzing the genetics of cancers from different parts of the body may reveal surprising details useful for treatment and prevention.
Dec 21, 2009 - 4:59:36 AM

Latest Research
Lung cancer and melanoma laid bare
Research teams led by the Wellcome Trust Sanger Institute announce the first comprehensive analyses of cancer genomes.
Dec 16, 2009 - 4:59:36 AM

Latest Research
Nanoprobes hit targets in tumors, could lessen chemo side effects
WEST LAFAYETTE, Ind. - Tiny nanoprobes have shown to be effective in delivering cancer drugs more directly to tumor cells - mitigating the damage to nearby healthy cells - and Purdue University research has shown that the nanoprobes are getting the drugs to right cellular compartments.
Dec 14, 2009 - 4:59:36 AM

Latest Research
Novel detection method unmasks circulating breast cancer cells
SAN ANTONIO - Circulating metastatic breast cancer cells can lose their epithelial receptors, a process that enables them to travel through the bloodstream undetected, according to research from The University of Texas M. D. Anderson Cancer Center.
Dec 11, 2009 - 4:59:36 AM

Latest Research
A new mouse could help understand how some lung cancer cells evade drug treatment
Lung cancer is the leading cause of cancer mortality worldwide and lung adenocarcinoma is the most common type. Many cases of lung adenocarcinoma are attributed to a mutation in a gene for the epidermal growth factor receptor (EGFR). Lung cancer with changes in EGFR is initially treatable with a family of chemotherapeutic agents called tyrosine kinase inhibitors (TKIs), such as gefitinib and erlotinib. However, patients often develop resistance to these drugs through the acquisition of additional changes or secondary mutations that allow cancer cells to evade treatment.
Dec 9, 2009 - 4:59:36 AM

Latest Research
Controversial kidney transplant technique could provide lifeline for very ill patients
Surgeons who successfully performed kidney transplants after removing small cancerous and benign masses from the donated organs, have published their results in the December issue of the urology journal BJUI.
Dec 7, 2009 - 4:59:36 AM

Latest Research
Defibrotide improves response rate in patients with severe veno-occlusive disease of the liver
Defibrotide, a novel drug which modulates the response of blood vessels to injury, was markedly more effective than standard treatment in post-stem cell transplant patients with hepatic veno-occlusive disease, a life threatening toxicity of transplant caused by blockages in tiny blood vessels of the liver, according to a study led by Dana-Farber Cancer Institute scientists.
Dec 7, 2009 - 4:59:36 AM

Latest Research
Era of Hope Scholar Award funds unique breast cancer research
HOUSTON - A novel approach to detecting and targeting flaws in first line of defense against cancer has earned an Era of Hope Scholar Award from the U.S. Department of Defense for a scientist at The University of Texas M. D. Anderson Cancer Center.
Dec 2, 2009 - 4:59:36 AM

Latest Research
Common pain relief medication may encourage cancer growth
Although morphine has been the gold-standard treatment for postoperative and chronic cancer pain for two centuries, a growing body of evidence is showing that opiate-based painkillers can stimulate the growth and spread of cancer cells. Two new studies advance that argument and demonstrate how shielding lung cancer cells from opiates reduces cell proliferation, invasion and migration in both cell-culture and mouse models.
Nov 18, 2009 - 4:59:36 AM

Latest Research : Cancer
Faulty immune memory can trigger cold sores
A faulty immune memory can trigger infections that may lead to cold sores and even cancer in some people, say researchers.
Nov 12, 2009 - 12:35:46 PM

Latest Research : Cancer : Breast Cancer
Study finds higher risk of cancer recurrence in women with dense breasts
Women with heavier busts who have been treated for breast cancer are at higher risk of its recurrence, says a new study.
Nov 10, 2009 - 12:14:32 PM

Latest Research
Minimally invasive surgery shown safe and effective treatment for rectal cancer
Laparoscopic surgery has been used in the treatment of intestinal disorders for close to 20 years, but its benefits have only recently begun to be extended to people with rectal cancer. In a prospective study of 103 patients who underwent straightforward or hand-assisted laparoscopic surgery for rectal cancer, a team of colon and rectal surgeons at NewYork-Presbyterian Hospital/Weill Cornell Medical Center has shown that the minimally invasive approach can be as effective as traditional open surgery in treating rectal cancers.
Nov 10, 2009 - 4:59:36 AM

Latest Research
St. Jude and UF Proton Therapy Institute to begin proton therapy clinical trial
St. Jude Children's Research Hospital and the University of Florida Proton Therapy Institute have formed a collaboration to provide proton therapy for St. Jude patients. The announcement follows the approval of the first clinical study to evaluate the use of proton therapy for rare brain cancers in children younger than 3 years old.
Nov 9, 2009 - 4:59:36 AM

Latest Research
Cancer patients want honesty, compassion from their oncologist
What do patients want from their radiation oncologists? The most significant preference is that more than one-third of female cancer patients (37 percent) prefer to have their hands held by their radiation oncologists during important office visits, compared to 12 percent of men, according to a randomized study presented November 4, 2009, at the 51st Annual Meeting of the American Society for Radiation Oncology (ASTRO).
Nov 4, 2009 - 4:59:36 AM

Latest Research
Low cholesterol may shrink risk for high-grade prostate cancer
Men with lower cholesterol are less likely than those with higher levels to develop high-grade prostate cancer - an aggressive form of the disease with a poorer prognosis, according to results of a Johns Hopkins collaborative study.
Nov 3, 2009 - 4:59:36 AM

Latest Research
Shorter radiation course stops cancer growth in high-risk prostate cancer patients
Hypofractionated radiation treatment, a newer type of radiation treatment that delivers higher doses of radiation in fewer treatments than conventional radiation therapy, is significantly more effective in stopping cancer from growing in high risk patients, compared to receiving standard radiation treatment, according to a study presented November 4, 2009, at the 51st Annual Meeting of the American Society for Radiation Oncology (ASTRO). In addition, findings show there is no increased risk of negative side effects later in patients who undergo hypofractionated radiation.
Nov 3, 2009 - 4:59:36 AM

Latest Research
New treatment option emerging for some with early stage lung cancer
San Diego, Calif -- Patients with early stage, non-small cell lung cancer who are not able to undergo surgery, now have a highly effective treatment option. Physicians say that option, radical stereotactic radiosurgery performed with CyberKnife, leads to a 100 percent overall survival after three years in patients with good lung function before treatment. These are the results of a study presented today at the annual CHEST meeting in San Diego. The study is a semifinalist for an Alfred Soffer Research Award, selected for outstanding original scientific research.
Nov 3, 2009 - 4:59:36 AM

Latest Research
Short-term hormone therapy added to radiation increases survival for medium-risk, but not low-risk, prostate cancer patients
Short-term hormone therapy given prior to and during radiation treatment to medium-risk prostate cancer patients increases their chance of living longer, compared to those who receive radiation alone, however there is no significant benefit for low-risk patients, according to the largest randomized study of its kind presented at the plenary session November 2, 2009, at the 51st Annual Meeting of the American Society for Radiation Oncology (ASTRO).
Nov 2, 2009 - 4:59:36 AM

Latest Research
Proton therapy is well-tolerated in prostate cancer patients
Proton beam therapy can be safely delivered to men with prostate cancer and has minimal urinary and rectal side effects, according to a study presented November 2, 2009, at the American Society for Radiation Oncology's 51st Annual Meeting in Chicago.
Nov 2, 2009 - 4:59:36 AM

Latest Research
Obesity significantly increases side effects of stereotactic body radiation therapy in lung cancer patients
Obesity, not the amount of radiation given, is the greatest factor in whether early-stage lung cancer patients develop chest wall pain after receiving stereotactic body radiation therapy to the chest wall, with obese patients being more than twice as likely to develop chronic pain compared to those who have less body weight, according to a first-of-its-kind study presented Tuesday, November 3, 2009, at the 51st Annual Meeting of the American Society for Radiation Oncology (ASTRO).
Nov 2, 2009 - 4:59:36 AM

Latest Research
Short-term hormone therapy and intermediate dose radiation increases survivial for early stage prostate cancer
Short-term hormone therapy given prior to and during intermediate dose radiation treatment for men with early stage prostate cancer increases their chance of living longer, compared to those who receive the same radiation alone, according to a Radiation Therapy Oncology Group (RTOG) study, the largest randomized trial of its kind, presented November 2, 2009, at the American Society for Radiation Oncology (ASTRO) annual meeting. The RTOG trial noted that this benefit appeared to be greatest for men currently defined as at medium-risk for disease failure.
Nov 2, 2009 - 4:59:36 AM

Latest Research
Adding proton therapy 'boost' to X-ray radiation therapy reduces prostate cancer recurrences
Men who receive a boost of proton therapy after receiving a standard course of X-ray radiation therapy have fewer recurrences of their prostate cancer compared to men who did not receive the extra dose of proton radiation, according to a first-of-its-kind study presented November 2, 2009, at the American Society for Radiation Oncology's 51st Annual Meeting in Chicago. The multi-institutional, randomized trial also shows that the high dose treatment is safe for these patients and causes no severe problems later with urinary or bowel functions.
Nov 2, 2009 - 4:59:36 AM

Latest Research
Discovery offers potential new pancreatic cancer treatment
Tiny particles that can carry drugs and target cancer cells may offer treatment hope for those suffering with pancreatic cancer. New research to be presented in November at the American Association of Pharmaceutical Scientists (AAPS) Annual Meeting in Los Angeles reveals that tumor-penetrating microparticles (TPM) have been specifically designed to break through hard-to-infiltrate barriers and deliver drugs more effectively and efficiently than the standard form of chemotherapy such as those injected through a vein.
Nov 2, 2009 - 4:59:36 AM

Latest Research
UCSF diabetes, brain tumor stem cell grants to drive development of therapies
Two teams of UCSF scientists have received grants from the California Institute for Regenerative Medicine to advance their stem cell based strategies for treating diabetes and brain tumors. The intent of the grants is for teams to file new drug applications to the U.S. Food and Drug Administration within four years, driving potential therapies toward clinical trials.
Oct 29, 2009 - 3:59:36 AM

Latest Research
NIEHS awards Recovery Act funds to address bisphenol A research gaps
For Immediate ReleaseWednesday, October 28, 2009
Oct 28, 2009 - 3:59:36 AM

Latest Research
Engineering center to probe forces that cause cancer to spread
Researchers from the Johns Hopkins Institute for NanoBioTechnology have been awarded $14.8 million from the National Cancer Institute to launch a research center aimed at unraveling the physical underpinnings of the growth and spread of cancer.
Oct 26, 2009 - 3:59:36 AM

Latest Research
2009 Pearl Meister Greengard Prize goes to pioneering geneticist
The recipient of the 2009 Pearl Meister Greengard Prize is Australian geneticist Suzanne Cory, professor and former director of the Walter and Eliza Hall Institute of Medical Research. Created to recognize the accomplishments of outstanding female scientists and administered by The Rockefeller University, the prize will be presented at a ceremony in the university's Caspary Auditorium on November 5.
Oct 26, 2009 - 3:59:36 AM

Latest Research
Depression in older cancer patients can be effectively treated with collaborative approach
Depression in older cancer patients can be effectively treated with collaborative approach in primary-care settings
Oct 20, 2009 - 3:59:36 AM

Latest Research
Exercise can aid recovery after brain radiation
DURHAM, N.C. -- Exercise is a key factor in improving both memory and mood after whole-brain radiation treatments in rodents, according to data presented by Duke University scientists at the Society for Neuroscience meeting.
Oct 18, 2009 - 3:59:36 AM

Latest Research
Case Western Reserve University receives $20.5 million
Case Western Reserve University has received a $20.5 million gift from Donald Goodman, DDS (DEN '45) and Ruth Weber Goodman.
Oct 13, 2009 - 3:59:36 AM

Latest Research
Study finds no relationship between PCR rate and race in women with breast cancer
SAN FRANCISCO - Locally advanced breast cancer patients who received the same class of neoadjuvant chemotherapy were found to have no evidence of disease at the time of their surgery, or achieved pathological complete response, at the same rate regardless of race, according to researchers at The University of Texas M. D. Anderson Cancer Center.
Oct 9, 2009 - 3:59:36 AM

Latest Research
M. D. Anderson team chosen to help navigate Cancer Genome Atlas
HOUSTON -- The Cancer Genome Atlas (TCGA) will fund an effort by scientists at The University of Texas M. D. Anderson Cancer Center to siphon buckets of meaningful information from an ocean of data about the aberrant genetics that drive human cancers.
Oct 7, 2009 - 3:59:36 AM

Latest Research
Strategy for mismatched stem cell transplants triggers protection against graft-vs.-host disease
BOSTON--A new technique being tested in stem-cell transplants from imperfectly matched donors has revealed a striking, unforeseen response that can suppress graft-versus-host disease, a common and dangerous complication of mismatched transplants, report scientists from Dana-Farber Cancer Institute.
Oct 7, 2009 - 3:59:36 AM

Latest Research
Prostate cancer gives a new outlook on life
Men who have prostate cancer often feel quite healthy, but the diagnosis still gives them a whole new outlook on life. Once they have learned to live with their cancer, they choose to focus on valuable relationships and appreciate the little things in life, shows a dissertation thesis from the Sahlgrenska Academy at the University of Gothenburg, Sweden.
Oct 5, 2009 - 3:59:36 AM

Latest Research
DNA test could be key to targeting treatments for head and neck cancer
It is estimated that more than 7,000 people are diagnosed with head and neck cancer each year in the UK and approximately 3,500 cases result in death. These cancers include tumours of the mouth, lips, throat and voice-box, and some have been linked to the sexually transmitted infection, HPV-16. Scientists at Liverpool analysed the DNA of more than 90 cancerous tissue samples to look for genes that indicated infection.
Oct 5, 2009 - 3:59:36 AM

Latest Research
NIH announces expansion of Rare Diseases Clinical Research Network
The National Institutes of Health announced today a second phase of the Rare Diseases Clinical Research Network (RDCRN) including funds for 19 research consortia. The Rare Diseases Clinical Research Consortia and a Data Management Coordinating Center (DMCC) will be awarded a total of just over $117 million over the next five years. The research conducted with the new funding will explore the natural history, epidemiology, diagnosis, and treatment of more than 95 rare diseases.
Oct 5, 2009 - 3:59:36 AM

Latest Research
Revolutionary statewide UC collaboration targets breast cancer
The University of California is launching an unprecedented statewide collaboration for breast cancer patients with the goal of revolutionizing the course of their care by designing and testing new approaches to research, technology and health care delivery.
Sep 29, 2009 - 3:59:36 AM

Latest Research
Research needed to learn which DCIS patients may be candidates for less invasive therapy
Ductal carcinoma in situ (DCIS), the most common non-invasive lesion of the breast, presents unique challenges for patients and providers largely because the natural course of the untreated disease is not well understood. Because most women diagnosed with DCIS are treated, it is difficult to determine the comparative benefits of different treatment strategies versus active surveillance, meaning systematic followup. An independent panel convened by the NIH urged the scientific community to identify appropriate biomarkers and other prognostic factors to better predict the risk of developing breast cancer.
Sep 24, 2009 - 3:59:36 AM

Latest Research
Prestigious $4.9 million NIH grant awarded to Case Western Reserve for colon cancer research
A prestigious National Institutes of Health (NIH) Transformative R01 Program grant for $4.9 million has been awarded to Case Western Reserve University School of Medicine. The five-year grant will fund research to identify patients' inborn genetic susceptibility to the development of colon cancer metastasis. Case Western Reserve was one of only 42 recipients of this competitive new grant designed to support exceptionally innovative, high risk, original and/or unconventional research projects that have the potential to create or overturn fundamental paradigms.
Sep 24, 2009 - 3:59:12 AM

Latest Research
ESMO recognizes leading oncologists with prestigious awards
The European Society for Medical Oncology (ESMO) has recognized the outstanding achievements of three leading cancer specialists with its three prestigious annual awards: the 2009 ESMO Award, Hamilton Fairley Award and ESMO Lifetime Achievement Award.
Sep 22, 2009 - 3:59:36 AM

Latest Research
Researcher awarded $1.2 million grant to study centrosomes and cilia
TALLAHASSEE, Fla. -- If you don't know how a human cell is supposed to work, it's hard to offer a good explanation when the cell goes haywire -- as it does in cancer. That's why a Florida State University College of Medicine researcher has been awarded a $1.2 million grant to explore the role of centrosomes and cilia in cell division and development and their connections to human disease.
Sep 22, 2009 - 3:59:36 AM

Latest Research
NIH funds grantees focusing on epigenomics of human health and disease
The National Institutes of Health announced today that it will fund 22 grants on genome-wide studies of how epigenetic changes -- chemical modifications to genes that result from diet, aging, stress, or environmental exposures -- define and contribute to specific human diseases and biological processes.
Sep 16, 2009 - 3:59:36 AM

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