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Latest Research : Cancer : Breast Cancer
  Last Updated: Nov 2, 2013 - 11:52:55 AM

Latest Research : Cancer : Breast Cancer
Blood test predicts breast cancer recurrence
London, Jan 20 - A simple blood test could tell whether the commonest form of breast cancer will recur post therapy, sparing women unwanted treatment with anti-cancer drugs.
Jan 20, 2013 - 7:22:02 PM

Latest Research : Cancer : Breast Cancer
Interferon-stimulated gene 15 (ISG15), a ubiquitin like protein, is a new therapeutic target for breast cancer
In a study published in the January 2012 issue of Experimental Biology and Medicine, Dr. Shyamal Desai and her co-investigators report that gene knock-down studies demonstrate that elevated ISG15 pathway results in disruption of the cytoskeletal architecture of breast cancer cells. ISG15 also inhibits degradation of cellular proteins involved in cell motility, invasion, and metastasis, promoting breast cancer cell migration
Jan 12, 2012 - 1:44:02 AM

Latest Research : Cancer : Breast Cancer
Smoking may have an association with breast cancer in women
Smoking before menopause, especially prior to giving birth, may be associated with a modest increase in the risk of developing breast cancer, according to a report in the January 24 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Jan 24, 2011 - 4:14:34 PM

Latest Research : Cancer : Breast Cancer
Vitamins and calcium supplements appear to reduce the risk of breast cancer
Vitamins and calcium supplements appear to reduce the risk of breast cancer, according to findings presented at the American Association for Cancer Research 101st Annual Meeting 2010.
Apr 18, 2010 - 12:03:32 PM

Latest Research : Cancer : Breast Cancer
Acupuncture has added benefits in breast cancer patients
Not only is acupuncture as effective as drug therapy at reducing hot flushes in breast cancer patients, it has the added benefit of potentially increasing a woman's sex drive and improving her sense of well-being, according to a Henry Ford Hospital study.
Dec 30, 2009 - 1:37:15 PM

Latest Research : Cancer : Breast Cancer
Study finds higher risk of cancer recurrence in women with dense breasts
Women with heavier busts who have been treated for breast cancer are at higher risk of its recurrence, says a new study.
Nov 10, 2009 - 12:14:56 PM

Latest Research : Cancer : Breast Cancer
Physical activity after menopause reduces breast cancer
Several studies had previously suggested that regular physical exercise reduces the breast cancer risk of women. However, it had been unknowned just how much exercise women should take in which period in life in order to benefit from this protective effect. Moreover, little was known about which particular type of breast cancer is influenced by physical activity. Answers to these questions are now provided by the results of the MARIE study.
Jan 15, 2009 - 3:12:21 PM

Latest Research : Cancer : Breast Cancer
Genes responsible for susceptibility to breast cancer metastasis can be inherited
New research in mice and five independent collections of human breast tumors has enabled National Cancer Institute (NCI) scientists to confirm that genes for factors contributing to susceptibility for breast cancer metastasis can be inherited. The new findings support earlier results from the same laboratory and appear in the Jan. 1, 2009, issue of Cancer Research.
Jan 4, 2009 - 2:07:19 PM

Latest Research : Cancer : Breast Cancer
Oestrogen therapy of benefit in some women with metastatic cancer
For breast cancer survivors, the idea of taking estrogen pills is almost a taboo. In fact, their doctors give them drugs to get rid of the hormone because it can fuel the growth of breast cancer. So these women would probably be surprised by the approach taken by breast cancer physician Matthew Ellis, M.B., Ph.D., associate professor of medicine at Washington University School of Medicine in St. Louis — he has demonstrated that estrogen therapy can help control metastatic breast cancer.
Dec 12, 2008 - 1:43:48 PM

Latest Research : Cancer : Breast Cancer
Awry protein linked to breast cancer
Sydney, Oct 9 - A developmental protein like Notch that sometimes goes awry has been linked to breast cancer, according to a new study.

Oct 9, 2008 - 9:41:11 AM

Latest Research : Cancer : Breast Cancer
Ultrasound-guided fine needle aspiration (USFNA) of the lymph nodes is -a useful preoperative staging for breast cancer
Ultrasound-guided fine needle aspiration (USFNA) of the lymph nodes is a safe, useful, and minimally invasive procedure for diagnosing metastatic disease in patients who are undergoing preoperative staging for breast cancer, according to a recent study conducted by researchers at the Rhode Island Hospital/Warren Alpert Medical School of Brown University in Providence, RI.
Apr 12, 2008 - 10:09:03 AM

Latest Research : Cancer : Breast Cancer
Screening mammography in elderly patients beneficial
Although guidelines keep changing regarding screening mammography in elderly patients, those older than 70 years old continue to benefit from this exam, showing that with frequent mammograms breast cancers can be found sooner, according to a recent study conducted by researchers at Jacobi Medical Center and Albert Einstein College of Medicine, in Bronx, NY.

Apr 12, 2008 - 4:00:00 AM

Latest Research : Cancer : Breast Cancer
Obesity causes breast cancer to be aggressive
Women with breast cancer have more aggressive disease and lower survival rates if they are overweight or obese, according to findings published in the March 15 issue of Clinical Cancer Research, a journal of the American Association for Cancer Research.


Mar 14, 2008 - 11:03:17 AM

Latest Research : Cancer : Breast Cancer
Why tumour cells are herceptin resistant
UC Davis Cancer Center researchers have discovered a likely reason why some tumor cells are inherently resistant — or become resistant over time — to the popular breast cancer drug trastuzumab, commonly referred to by the brand name Herceptin.
Mar 8, 2008 - 7:47:45 AM

Latest Research : Cancer : Breast Cancer
Which is better-Lapatinib and/or Trastuzumab? International study to answer this
Two targeted medications designed to treat an aggressive form of breast cancer are being tested in a new study involving 8,000 participants in 50 countries across six continents -- a clinical trial that investigators hope will provide a new model for global cancer research. This trial, dubbed ALTTO (Adjuvant Lapatinib and/or Trastuzumab Treatment Optimization study), will be one of the first global initiatives in which two large, academic breast cancer research networks covering different parts of the world have jointly developed a study in which all care and data collection are standardized, regardless of where patients are treated.
Mar 1, 2008 - 3:36:33 AM

Latest Research
Breast cancer diagnosis comes late for women in gentrifying neighborhoods
Women who live in Chicago's gentrifying neighborhoods are more apt to receive a late diagnosis of breast cancer than women who live in poverty-stricken neighborhoods, University of Illinois at Chicago researchers have found.

Feb 5, 2008 - 11:30:00 PM

Latest Research : Cancer : Breast Cancer
Fighting resistance to tamoxifen- breakthrough in breast cancer treatment
Researchers at the Tenovus Centre for Cancer Research at Cardiff University have made a breakthrough in breast cancer treatment that could help save the lives of women who become resistant to breast cancer drugs such as tamoxifen.
Jan 20, 2008 - 9:17:51 AM

Latest Research : Cancer : Breast Cancer
Lapatinib (Tykerb) and capecitabine (Xeloda) shrink breast cancer metastases in the brain
A combination of a "targeted" therapy and chemotherapy shrank metastatic brain tumors by at least 50 percent in one-fifth of patients with aggressive HER2-positive breast cancer, according to data presented by Dana-Farber Cancer Institute investigators at the San Antonio Breast Cancer Symposium.
Dec 16, 2007 - 9:57:43 AM

Latest Research : Cancer : Breast Cancer
Osteoporosis drug approved to cut breast cancer risk
In 1997, FDA approved Evista, which is manufactured by Eli Lilly and Company, for the prevention of osteoporosis in postmenopausal women and in 1999, for the treatment of osteoporosis in postmenopausal women.
Sep 15, 2007 - 1:39:48 PM

Latest Research
Study finds new link between estrogen and breast cancer
The female sex hormone estrogen turns on a gene linked to breast cancer, according to new research by Brisbane scientists.
Aug 24, 2007 - 3:37:00 AM

Latest Research : Cancer : Breast Cancer
Support groups don't extend survival of metastatic breast cancer patients, Stanford study finds
A new study from a team of Stanford University School of Medicine researchers led by David Spiegel, MD, shows that participating in support groups doesn't extend the lives of women with metastatic breast cancer. The results differ from oft-cited previous findings by Spiegel that showed group psychotherapy extended survival time.
Jul 23, 2007 - 4:00:00 AM

Latest Research : Radiology
Electromagnetic breast imaging techniques offer high contrast and ability to distinguish between healthy breast tissue and abnormal tissue
Dartmouth physicians and engineers have published a paper with results from a five-year project testing three new imaging techniques to examine breast abnormalities, including cancer. The study finds that the new methods of electromagnetic imaging offer a high contrast and the ability to distinguish between healthy breast tissue and abnormal tissue. Their study appears in the May 2007 issue of Radiology, the journal of the Radiological Society of North America.
Jun 6, 2007 - 4:02:00 PM

Latest Research
Study finds difference in survival rates among white and black women with advanced breast cancer
Despite modest overall improvements in breast cancer survival rates for women with advanced disease over the last two decades, the rates for black women have not improved and the difference in life expectancy between white and black women continues to widen, according to researchers at The University of Texas M. D. Anderson Cancer Center.
Jun 6, 2007 - 4:00:00 AM

Latest Research : Cancer : Breast Cancer
HRT Decline Reduced Breast Cancer Incidence
An extended analysis of cancer rates reinforces a strong association between use of hormone replacement therapy (HRT) and increased breast cancer incidence, according to research led by scientists at The University of Texas M. D. Anderson Cancer Center and published in the April 19th issue of the New England Journal of Medicine.
Apr 19, 2007 - 11:13:18 AM

Latest Research : Cancer : Breast Cancer
Should all women in 40s be routinely screened for breast cancer?
Should all women in their 40s be routinely screened for breast cancer? Not necessarily, according to the American College of Physicians. In a new set of guidelines for clinicians of 40-something patients, the group recommends that mammography screening decisions be made on a case-by-case basis. It advises clinicians to discuss the benefits and harms of screening with the patient, as well as each woman's individual cancer risk and preference about screening.
Apr 5, 2007 - 11:51:50 AM

Latest Research : Cancer : Breast Cancer
Computerized reminders boost mammography screening rates
Findings of a new Mayo Clinic study published this week in Archives of Internal Medicine show that a computerized mail and phone reminder program can significantly increase the percentage of patients receiving preventive health services and improve the value of health care.
Apr 5, 2007 - 11:46:38 AM

Latest Research : Cancer : Breast Cancer
Recent declines in breast cancer mortality most significant in women under 70
A new study shows that recent declines in breast cancer mortality rates have been most significant among women with estrogen receptor (ER)-positive tumors and women younger than 70. The results of the study are being published online April 2 in the Journal of Clinical Oncology (JCO).
Apr 3, 2007 - 3:03:56 AM

Latest Research : Cancer : Breast Cancer
Older women with breast cancer get a lower level of care than younger women
Compared to younger women, older women with breast cancer are less likely to be diagnosed via needle biopsy and triple assessment, less likely to undergo surgery and less likely to receive radiotherapy, the researchers report in this week's British Journal of Cancer.
Mar 30, 2007 - 1:56:18 AM

Latest Research : Cancer : Breast Cancer
UBC discovery may lead to focussed therapies for metastatic breast, ovarian cancer
New non-toxic and targeted therapies for metastatic breast and ovarian cancers may now be possible, thanks to a discovery by a team of researchers at the University of British Columbia.
Mar 19, 2007 - 11:01:56 PM

Latest Research : Cancer : Breast Cancer
Protein identified that regulates effectiveness of Taxol chemotherapy in breast cancer
Cancer researchers at Georgetown University Medical Center have taken a step towards understanding how and why a widely used chemotherapy drug works in patients with breast cancer.
Feb 22, 2007 - 7:58:26 AM

Latest Research : Cancer : Breast Cancer
Gab-2 protein may spur metastasis in breast cancer
A protein known for its ability to "bridge" interactions between other cellular proteins may spur metastasis in breast cancer, the disease’s deadliest stage, a study from Burnham Institute for Medical Research has found.
Feb 22, 2007 - 7:41:04 AM

Latest Research : Cancer : Breast Cancer
Study shows higher mortality rates in African and African American women with breast cancer
African and African American women are more likely to die of breast cancer than their white counterparts because they tend to get the disease before the menopause, suggests new research from the University of East Anglia and the Children�s Hospital Boston in collaboration with researchers in the US and Italy.
Feb 21, 2007 - 7:49:30 AM

Latest Research : Cancer : Breast Cancer
Breast cancers expressing IGF-1R are resistant to Herceptin
Using gene chips to profile tumors before treatment, researchers at Harvard and Yale Universities found markers that identified breast cancer subtypes resistant to Herceptin, the primary treatment for HER2-positive breast cancer. They say this advance could help further refine therapy for the 25 to 30 percent of breast cancer patients with this class of tumor.
Feb 20, 2007 - 8:37:17 AM

Latest Research : Cancer : Breast Cancer
Physical activity reduces the risk of invasive breast cancer
Six or more hours per week of strenuous recreational activity may reduce the risks of invasive breast cancer by 23 percent, according to researchers from the University of Wisconsin Paul P. Carbone Comprehensive Cancer Center (UWCCC). Their report in the February issue of Cancer Epidemiology Biomarkers & Prevention, based on a survey of over 15,000 women, shows that exercise has a protective effect against invasive breast cancer throughout a woman’s lifetime.

Feb 15, 2007 - 10:21:07 AM

Latest Research : Cancer : Breast Cancer
An integrated single genomic test would reveal ER and HER-2 status of breast cancer
Two critical characteristics of breast cancer that are important to treatment can be identified by measuring gene expression in the tumor, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in Lancet Oncology online.

Feb 15, 2007 - 2:39:19 AM

Latest Research : Cancer : Breast Cancer
Survey reveals that majority of breast cancer survivors do not understand the chance of recurrence
A unique survey of African American breast cancer survivors at heightened risk for hereditary breast cancer has found the majority do not believe they have an increased chance of developing the cancer again.
Feb 15, 2007 - 2:10:10 AM

Latest Research : Cancer : Breast Cancer
Early switch to aromatase inhibitors significantly improves survival rates in breast cancer
For breast cancer patients taking tamoxifen, switching to an aromatase inhibitor within three years significantly improves survival rates, according to a new study. Published in the March 15, 2007 issue of CANCER), a peer-reviewed journal of the American Cancer Society, the study reveals that the clear survival benefit was also achieved without an increased risk of death from other causes – a significant risk associated with tamoxifen.

Feb 12, 2007 - 3:55:04 AM

Latest Research : Cancer : Breast Cancer
New approaches in breast cancer management may lead to exciting new nonsurgical tools
Aggressive research currently underway brings hope of dramatic advances in breast cancer management, according to a new review. Published in the March 15, 2007 issue of CANCER a peer-reviewed journal of the American Cancer Society, the review reveals that new approaches in breast cancer imaging, investigations into the timing of chemotherapy, and research on breast cancer vaccines may lead to exciting new nonsurgical tools for the physician treating breast cancer patients. These new tools may significantly alter current screening and treatment paradigms used by surgical oncologists, as well improving the care of patients.

Feb 12, 2007 - 3:21:52 AM

Latest Research : Cancer : Breast Cancer
SPECT/CT imaging aids in better sentinel node identification in overweight women
Increasing the ability to identify sentinel nodes—the very first lymph nodes that trap cancer cells draining away from a breast lesion site—has a major impact in the treatment and outcome of breast cancer patients, possibly eliminating the need for unnecessary and painful surgery. Researchers found that using SPECT/CT imaging aids in sentinel node identification—especially for overweight or obese women, according to a report in the February issue of the Journal of Nuclear Medicine.
Feb 6, 2007 - 11:52:44 AM

Latest Research : Cancer : Breast Cancer
Epigenetic drugs, promising for breast cancer treatment
Worldwide, cancer persists as one of the most important diseases that affect the human being. The knowledge on the molecular bases of cancer generated during the last decades has been successfully translated into small but significant gains in overall cancer survival rates due to better primary prevention measures, improved diagnostic methods and the development of more effective and specific therapies, collectively termed "molecular targeted therapies". In the context of these new forms of treatment, epigenetic or transcriptional cancer therapy is clearly promising.
Dec 24, 2006 - 5:14:00 PM

Latest Research : Cancer : Breast Cancer
Breast cancer chemotherapy may deterioration in cognitive function
A new study investigating the effects of chemotherapy on cognitive function in mice has confirmed what many cancer patients receiving treatment have often complained about – a decline in their memory and other cognitive functions, sometimes characterized as "chemobrain". The study, led by Dr. Gordon Winocur of the Baycrest Research Centre for Aging and the Brain, in collaboration with Drs. Ian Tannock and Janette Vardy of Princess Margaret Hospital, was conducted at Trent University. The findings are published in the September 2006 issue of Pharmacology, Biochemistry and Behavior (Vol. 85, Issue 1), which will be available online in the next week. The results were presented at a workshop held in conjunction with the 8th World Congress of Psycho-Oncology in Venice last week.
Oct 29, 2006 - 9:32:00 PM

Latest Research : Cancer : Breast Cancer
Elderly Breast Cancer Patients May Be Under-Diagnosed And Under-Treated
Elderly patients with breast cancer who received care in a community hospital setting may have been under-diagnosed, under-staged and under-treated, according to a report in the October issue of Archives of Surgery, one of the JAMA/Archives journals. The number of older breast cancer patients has increased along with overall elderly population, according to background information in the article. About half of breast cancer patients are older than 65 years and 35 percent are older than 70; 77 percent of breast cancer deaths occur in women older than 55. Choosing the appropriate treatment for older patients is a challenge, because many have other serious illnesses in addition to their cancer that may threaten their health and shorten their lives. Questions remain about the best screening protocols for elderly women, as well. Some current guidelines suggest that women stop having mammograms at age 70, while others provide no upper limit.
Oct 17, 2006 - 2:34:00 PM

Latest Research : Cancer : Breast Cancer
Tissue Geometry Plays Crucial Role in Breast Cell Invasion
Apropos of National Breast Cancer Awareness month, researchers with the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) have created a first-of-its-kind model for studying how breast tissue is shaped and structured during development. The model may shed new light on how the misbehavior of only a few cells can facilitate metastatic invasion because it shows that the development of breast tissue, normal or abnormal, is controlled not only by genetics but also by geometry. Though created specifically for the study of breast tissue, this model should also be applicable to the study of tissue development in other organs as well.
Oct 13, 2006 - 11:02:00 AM

Latest Research : Cancer : Breast Cancer
Ethnic variations in hormone levels may cause differences in breast cancer risk
Researchers have known that a woman's natural hormone levels can affect her risk of developing breast cancer. A new study from the University of Southern California (USC) has found that the natural levels of estrogens in post-menopausal women varies by ethnicity and race, and may explain the differences in the groups' breast cancer rates. The study appears in the October issue of Cancer Epidemiology, Biomarkers & Prevention.
Oct 10, 2006 - 12:22:00 PM

Latest Research : Cancer : Breast Cancer
Researchers set benchmarks for screening mammography
A recent study of medical audit data funded by the National Cancer Institute (NCI) revealed that community mammography screening results surpass performance recommendations across the United States. Approximately 188 mammography facilities nationwide contributed to the study of more than 1.1 million women, who underwent at least one screening mammography exam between 1996 and 2002. The findings are reported in the October issue of Radiology.
Sep 26, 2006 - 11:10:00 PM

Latest Research : Cancer : Breast Cancer
Raloxifene Reduces Breast Cancer Risk in Postmenopausal Women at All Risk Levels
Raloxifene protects postmenopausal women from developing invasive breast cancer whether they are at high or low risk of developing the disease, according to a new study. The study, published in the September 1 issue of Clinical Cancer Research, also revealed that the drug appears to reduce risk in women with a family history of breast cancer down to a similar level to women without affected relatives. Compared with a placebo drug, the study found that use of raloxifene was associated with a 58 percent reduction in breast cancer risk in women without a family history of the disease, and an 89 percent reduction in risk for women with a family history of breast cancer.
Sep 13, 2006 - 12:03:00 PM

Latest Research : Cancer : Breast Cancer
Physical activity improves survival in breast cancer patients
Women who reported the highest levels of physical activity in the year before they were diagnosed with breast cancer may have higher survival, according to a new study.
Sep 11, 2006 - 4:45:00 PM

Latest Research : Cancer : Breast Cancer
Pedigree assessment tool correctly identifies women with higher risk of breast cancer
A new screening tool for the general practitioner effectively identifies patients at risk for hereditary breast cancer, according to a new study.
Sep 11, 2006 - 4:40:00 PM

Latest Research : Cancer : Breast Cancer
MRI more accurately determines cancer spread into breast ducts
MRI is better than MDCT for determining if and how far breast cancer has spread into the breast ducts and should be used before patients receive breast conserving therapy, a new study shows.
Sep 4, 2006 - 5:03:00 PM

Latest Research : Cancer : Breast Cancer
Core needle biopsy gives an accurate picture of gene expression
The gene expression profile detected in the core needle biopsy of a breast tumour is representative of gene expression in the whole tumour. A study published today in the open access journal Breast Cancer Research confirms the reliability of core needle biopsy as a tool in breast cancer diagnosis and prognosis. The study also shows that the gene expression profile of a core needle biopsy might be more accurate than the profile of a surgical sample taken from the same tumour, after the biopsy was carried out. According to the study results, the biopsy procedure seems to trigger the expression of genes involved in wound healing as well as tumour invasion and metastasis, thus modifying the gene expression profile of subsequent surgical samples.
Aug 19, 2006 - 4:40:00 PM

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