||Last Updated: Nov 17th, 2006 - 22:35:04
Spermatogonial stem cells could aid male infertility
Scientists have shown for the first time that sperm grown from embryonic stem cells can be used to produce offspring. The experiment was carried out using mice and produced seven babies, six of which lived to adulthood. The breakthrough, reported today, Monday July 10, in the academic journal Developmental Cell, helps scientists to understand more about how animals produce sperm. This knowledge has potential applications in the treatment of male infertility.
Jul 11, 2006, 00:05
Dopamine agonist can prevent ovarian hyperstimulation syndrome
A class of drug widely used in a number of gynaecological conditions can prevent ovarian hyperstimulation syndrome (OHSS), an infrequent but serious complication of assisted reproduction treatments, a scientist told the 22nd annual conference of the European Society of Human Reproduction and Embryology in Prague, Czech Republic, on Wednesday 21 June 2006. Dr. Claudio Alvarez, from the Instituto Valenciano de Infertilidad, Valencia, Spain, said that his team's work, using the dopamine agonist cabergoline, was the first successful attempt to prevent this disorder.
Jun 22, 2006, 05:07
CBT can restore ovulation in infertile women
Fertility can be restored in some women by the use of behavioural therapy, thus avoiding recourse to expensive medicines and complex procedures, a scientist told the 22nd annual conference of the European Society of Human Reproduction and Embryology in Prague, Czech Republic on Tuesday 20 June 2006. Professor Sarah L. Berga, from the Department of Gynecology and Obstetrics, Emory University, Atlanta, Georgia, USA, said that her work was the first to show that reducing stress through psychological intervention could restore ovulation in women whose ovarian function had previously been impaired.
Jun 20, 2006, 21:39
New method of testing ova for abnormalities
Italian researchers have shown for the first time that it is possible to test a woman's egg, before fertilisation, for chromosomal abnormalities that might make an embryo less likely to implant successfully or more likely to miscarry at a later stage.
Jun 20, 2006, 02:59
New Hope For Preserving Future Fertility
A new and highly successful method of freezing human eggs will help to even out the current inequality between men and women whereby, until now, men have been able to use their previously frozen sperm for IVF treatment but women have not been able to do the same with their eggs. The research gives hope to hundreds of women who want to preserve their future fertility but who, for whatever reason, only have eggs, not embryos, available for freezing. Dr Masashige Kuwayama told a news briefing that although sperm could be frozen, thawed and used for in vitro fertilisation with high levels of success, the freeze-thawing process could damage eggs and, until now, it had been very difficult to perform successful IVF using frozen-thawed eggs. Research by Professor Stefania Nottola and Dr Sandrine Chamayou, presented at the conference, gave examples of the current problems of conventional freeze-thawing and the need for more effective techniques. It is thought that worldwide less than 150 babies have been born using eggs that have been frozen.
Jun 20, 2006, 01:12
How IVF could be causing genetic errors in embryos
The conditions in which embryos are cultured in the laboratory during in vitro fertilisation could be causing genetic errors that are associated with certain developmental syndromes and other abnormalities in growth and development, such as low birth weight. Researchers told the 22nd annual conference of the European Society of Human Reproduction and Embryology today (Monday) that preliminary work investigating genetic imprinting in mouse embryos had shown that certain culture media and concentrations of oxygen altered the expression of several imprinted genes. Imprinting is the process by which some genes are activated or inactivated depending on whether they have been inherited in chromosomes from the mother or the father.
Jun 20, 2006, 00:39
Fertility drug letrozole given 'all-clear' in new study
Concerns about the use of letrozole, an easy-to-use and inexpensive drug for the treatment of infertility, appear to be unfounded, according to a major study co–authored by Dr. Togas Tulandi, Director of Division of Reproductive Endocrinology and Infertility, McGill University Health Centre (MUHC) and Chief of Obstetrics and Gynecology at the Jewish General Hospital, and Professor of Obstetrics and Gynecology at McGill University. Their findings, which are currently available in an early online edition of Fertility and Sterility, showed that babies whose mothers were treated with letrozole had the same rate of birth defects as those whose mothers were treated with clomiphene citrate – the low-risk, first-line treatment for infertility for more than 40 years.
Apr 22, 2006, 18:57
Major birth defect risk more for IVF babies
Babies conceived through in vitro fertilization (IVF), a method of assisted reproduction, have a slightly increased risk of major birth defects, such as heart or muscle and skeletal defects, compared to babies conceived naturally, according to a University of Iowa study. The risk for IVF babies was 6.2 percent compared to 4.4 percent for naturally conceived babies. While the finding suggests a relationship between IVF and slightly more birth defects, it does not prove that the IVF procedure itself is the cause. However, questions raised by the investigation are important to address because nearly 1 percent of all children born in the United States are conceived through IVF, said Brad Van Voorhis, M.D., the F.K. "Ted" Chapler Professor of Reproductive Endocrinology in the UI Roy J. and Lucille A. Carver College of Medicine and a study author.
Dec 1, 2005, 05:40
Treatment of Men with ED Improves Women's Sexual Function
Couples share wine, movies, vacations and bedrooms. Do couples also share sexual problems and solutions? In the November issue of The Journal of Sexual Medicine, researchers have published the first-ever prospective, double-blind, placebo-controlled, multi-institutional treatment study with multi-dimensional psychometrically valid outcomes and concluded that an effective erectile dysfunction treatment in men also significantly improved sexual function and sexual satisfaction in untreated women partners. The research concluded that women partners' sexual function improvements related significantly and consistently to treatment-related improvements in men's erectile function. Furthermore, erectile dysfunction management should acknowledge that both members of the couple may be affected by erectile dysfunction and its treatment.
Oct 27, 2005, 00:04
Fertility awareness-based methods of family planning & timing - Study
Couples who use fertility awareness-based methods of family planning have sex just as often as couples who use other contraceptive methods -- they just time it differently, according to a new Georgetown University Institute for Reproductive Health study to be published in a forthcoming edition of the Journal of Biosocial Science. The study is now available online on the journal's website.
Oct 12, 2005, 04:50
Fertility enhanced with Vitamin E- Galactose hybrid polymer
The sperm vitality of pigs can be enhanced and fertility rates increased through the use of a new hybrid polymer, according to research led by Dr Ben Davis of the Department of Chemistry. The approach might be used to increase sperm vitality and lifespan in other mammals, for example during human infertility treatment.
Sep 29, 2005, 20:56
New way of studying sperm function
A new way of studying sperm function has been developed which will aid research into male infertility. An international team led by Oxford researchers has shown for the first time that it is possible to introduce a synthetic gene (a transgene) directly into a normal, live animal in such a way that the gene is expressed in mature sperm. The new method could be extremely important for fertility research because it allows many different aspects of gene function in sperm to be studied. The study showed that the gene coding for a fluorescent green protein, originally taken from a jellyfish, could be introduced into sperm precursor cells within the testicles of a hamster, resulting in green, glowing sperm. Hamsters were used in the study because their sperm have many attributes in common with those of humans, and thus offer an excellent model for studying human sperm development and how defects in this process might result in infertility.
Sep 20, 2005, 22:11
Successful transplant of frozen-thawed ovaries
Israeli scientists report today in Human Reproduction Journal that they have successfully transplanted whole frozen and thawed ovaries in sheep, retrieved oocytes from these ovaries and triggered them in the laboratory into early embryonic development.
Sep 15, 2005, 17:47
Understanding beta estrogen receptor role may help treat infertility
New research suggests that medications commonly referred to as fertility drugs may be ineffective for women who lack a gene called the estrogen receptor beta. The study showed that fertility drugs did not improve ovulation rates in mice that were genetically engineered to lack estrogen receptor beta. The estrogen receptor beta is one of two estrogen receptor proteins which mediate the effects of estrogen hormones and are present throughout the female reproductive tissues. These new data indicate that this receptor plays a critical role in ovulation, and suggests that women who do not have this receptor may benefit more from alternative infertility treatments.
Jul 22, 2005, 00:36
Prochieve Gel Doubles the Rate of Pregnancy in Infertile Women on Clomiphene
The study suggests that administering a sequential estrogen and progesterone supplementation regimen, including Prochieve(R) 8%, with clomiphene citrate (CC) cycles in oligo-ovulatory and anovulatory women may more than double the rate of pregnancy, as compared to clomiphene citrate therapy alone, but, because this was a pilot study, the difference did not reach statistical significance.
Jun 21, 2005, 21:33
Scientists Identify Infertility Molecule
Scientists at The Scripps Research Institute are reporting that mice created to lack a certain type of molecule known as an LPA receptor have fertility problems, which suggests that these receptors play a major role in conception.
May 8, 2005, 14:52