RxPG News Feed for RxPG News

Medical Research Health Special Topics World
  Home
 
   Health
 Aging
 Asian Health
 Events
 Fitness
 Food & Nutrition
 Happiness
 Men's Health
 Mental Health
 Occupational Health
 Parenting
 Public Health
 Sleep Hygiene
 Women's Health
 
   Healthcare
 Africa
 Australia
 Canada Healthcare
 China Healthcare
 India Healthcare
 New Zealand
 South Africa
 UK
 USA
 World Healthcare
 
   Latest Research
 Aging
 Alternative Medicine
 Anaethesia
 Biochemistry
 Biotechnology
 Cancer
 Cardiology
 Clinical Trials
 Cytology
 Dental
 Dermatology
 Embryology
 Endocrinology
 ENT
 Environment
 Epidemiology
 Gastroenterology
 Genetics
 Gynaecology
 Haematology
 Immunology
 Infectious Diseases
 Medicine
 Metabolism
 Microbiology
 Musculoskeletal
 Nephrology
 Neurosciences
 Obstetrics
 Ophthalmology
 Orthopedics
 Paediatrics
 Pathology
 Pharmacology
 Physiology
 Physiotherapy
 Psychiatry
 Radiology
 Rheumatology
 Sports Medicine
 Surgery
 Toxicology
 Urology
 
   Medical News
 Awards & Prizes
 Epidemics
 Launch
 Opinion
 Professionals
 
   Special Topics
 Ethics
 Euthanasia
 Evolution
 Feature
 Odd Medical News
 Climate

Last Updated: Oct 11, 2012 - 10:22:56 PM
Obstetrics Channel

subscribe to Obstetrics newsletter
Latest Research : Obstetrics

   EMAIL   |   PRINT
Recurrence of pre-eclampsia across generations

Sep 19, 2005 - 4:29:00 PM
Men born after a pregnancy complicated by pre-eclampsia also had a moderately increased risk of fathering a pre-eclamptic pregnancy.

 
[RxPG] Genes from both the mother and father can trigger pre-eclampsia, finds a study published online by the BMJ.

Pre-eclampsia is a serious condition where abnormally high blood pressure and other disturbances develop in the second half of pregnancy. It occurs in 3-5% of pregnancies and is dangerous for both mother and child.

Researchers in Norway used birth registry data to study whether men and women who are born after pre-eclamptic pregnancies pass on this risk to the next generation, compared with those who had no family history of pre-eclampsia.

They found that daughters of women who had pre-eclampsia during pregnancy had more than twice the risk of pre-eclampsia themselves compared with other women. Men born after a pregnancy complicated by pre-eclampsia also had a moderately increased risk of fathering a pre-eclamptic pregnancy.

These associations were stronger for the more severe types of pre-eclampsia.

Sisters of affected men or women, but who were not themselves born after a pre-eclampic pregnancy, also had an increased risk. However, for brothers, the risk of fathering a pre-eclamptic pregnancy was similar to that in men with no family history.

This suggests that maternal susceptibility can pass from mother to daughter but not from mother to son, write the authors.

These results support the theory that both the mother’s and the father’s genes contribute to the risk of pre-eclampsia, say the authors. The risk through affected mothers is higher because they carry their mother’s susceptibility genes and also transmit independent genetic risk factors to their unborn child. The risk through affected fathers is lower because fathers transmit only fetal risk genes.



Publication: Recurrence of pre-eclampsia across generations: exploring fetal and maternal genetic components in a population based cohort, BMJ, 17 September 2005
On the web: Read the full text of the source article at bmj.com 

Advertise in this space for $10 per month. Contact us today.


Related Obstetrics News
progesterone can prevent apoptosis in fetal membranes and therefore prevent pre-term birth
Anxious women more likely to have smaller babies
Preeclampsia -a disorder of protein misfolding
Depression during pregnancy doubles risk of premature delivery
Computer programme to predict premature births under development
Predictor of miscarriages
Elevated autoantibodies linked to preeclampsia
Vitamin D intake inadequate during pregnancy
Non-invasive alternative to amniocentesis ?
Advanced Maternal Age is an Independent Predictor of Intrauterine Fetal Death at Term

Subscribe to Obstetrics Newsletter

Enter your email address:


 Feedback
For any corrections of factual information, to contact the editors or to send any medical news or health news press releases, use feedback form

Top of Page

 
Contact us

RxPG Online

Nerve

 

    Full Text RSS

© All rights reserved by RxPG Medical Solutions Private Limited (India)