RxPG News Feed for RxPG News

Medical Research Health Special Topics World
  Home
 
   Health
 Aging
 Asian Health
 Events
 Fitness
 Food & Nutrition
 Happiness
 Men's Health
 Mental Health
 Occupational Health
 Parenting
 Public Health
 Sleep Hygiene
 Women's Health
 
   Healthcare
 Africa
 Australia
 Canada Healthcare
 China Healthcare
 India Healthcare
 New Zealand
 South Africa
 UK
 USA
 World Healthcare
 
 Latest Research
 Aging
 Alternative Medicine
 Anaethesia
 Biochemistry
 Biotechnology
 Cancer
 Cardiology
 Clinical Trials
 Cytology
 Dental
 Dermatology
 Embryology
 Endocrinology
 ENT
 Environment
 Epidemiology
 Gastroenterology
 Genetics
 Gynaecology
 Haematology
 Immunology
 Infectious Diseases
 Medicine
 Metabolism
 Microbiology
 Musculoskeletal
 Nephrology
 Neurosciences
 Obstetrics
 Ophthalmology
 Orthopedics
 Paediatrics
 Pathology
 Pharmacology
 Physiology
 Physiotherapy
 Psychiatry
 Radiology
 Rheumatology
 Sports Medicine
 Surgery
 Toxicology
 Urology
 
   Medical News
 Awards & Prizes
 Epidemics
 Launch
 Opinion
 Professionals
 
   Special Topics
 Ethics
 Euthanasia
 Evolution
 Feature
 Odd Medical News
 Climate

Last Updated: Feb 19, 2013 - 1:22:36 AM
Research Article
Latest Research Channel

subscribe to Latest Research newsletter
Latest Research

   EMAIL   |   PRINT
Could the immune system help recovery from stroke?

Mar 13, 2012 - 4:00:00 AM
Within TargetBraIn we want to reinforce the positive effects of inflammation and reduce its negative effects. This could be achieved either by trying to change the immune system's reactions or through stem cell therapy, or both! A combination of the two methods may produce the best results, says Zaal Kokaia.

 
[RxPG] Stroke and other diseases and injuries to the brain are often followed by inflammation, caused by a reaction of the body's immune system. This reaction has been seen as something that must be combated, but perhaps the immune system could in fact help with recovery following a stroke. A major new EU project, led by Lund University in Sweden and the Weizmann Institute in Israel, is going to study this question.

Stroke is a major public health problem, with 700 000 new cases in the EU and 30 000 new cases in Sweden each year. The EU is now investing EUR 12 million in the project TargetBraIn. The goal of the project is to gain a better understanding of the role of the immune system in stroke.

The immune system protects the body when its tissues are damaged for whatever reason. The cells of the immune system often produce inflammation, which has some negative effects, but which in time helps the original damage to heal.

Stroke is most commonly caused by a cerebral infarction (a blood clot in the brain), which starves the brain of oxygen. It is the damage caused by the lack of oxygen which activates the immune system and leads to inflammation. Until now, this has been seen as a wholly undesirable reaction. To emphasise the positive aspects of the immune system's reaction is therefore something of a paradigm shift in the field. Professor Michal Schwartz and her research group in Israel have pioneered the study of the positive role of the immune system in repairing damaged nerve cells.

Professor Zaal Kokaia, head of the Stem Cell Centre at Lund University, has long worked with stem cell therapy for brain injuries. He led StemStroke, an EU project which researched the possibility of creating new nerve cells after a stroke through transplants or by encouraging the brain to form new cells. Zaal Kokaia and Michal Schwartz are now coordinator and deputy coordinator respectively of TargetBraIn (an acronym which stands for Targeting Brain Inflammation for Improved Functional Recovery in Acute Neurodegenerative Disorders).

Within TargetBraIn we want to reinforce the positive effects of inflammation and reduce its negative effects. This could be achieved either by trying to change the immune system's reactions or through stem cell therapy, or both! A combination of the two methods may produce the best results, says Zaal Kokaia.

The research is still at the experimental stage, and the road to general application on patients will be long. However, as the population of Europe ages, stroke is becoming an increasingly costly disease, hence the EU investment in the field.



Related Latest Research News
Drug activates virus against cancer
Bone loss associated with increased production of ROS
Sound preconditioning prevents ototoxic drug-induced hearing loss in mice
Crystal methamphetamine use by street youth increases risk of injecting drugs
Johns Hopkins-led study shows increased life expectancy among family caregivers
Moderate to severe psoriasis linked to chronic kidney disease, say experts
Licensing deal marks coming of age for University of Washington, University of Alabama-Birmingham
Simple blood or urine test to identify blinding disease
Physician job satisfaction driven by quality of patient care
Book explores undiscovered economics of everyday life

Subscribe to Latest Research Newsletter

Enter your email address:


 Feedback
For any corrections of factual information, to contact the editors or to send any medical news or health news press releases, use feedback form

Top of Page

 
Contact us

RxPG Online

Nerve

 

    Full Text RSS

© All rights reserved by RxPG Medical Solutions Private Limited (India)