RxPG News Feed for RxPG News

Medical Research Health Special Topics World
 Asian Health
 Food & Nutrition
 Men's Health
 Mental Health
 Occupational Health
 Public Health
 Sleep Hygiene
 Women's Health
 Canada Healthcare
 China Healthcare
 India Healthcare
 New Zealand
 South Africa
 World Healthcare
 Latest Research
 Alternative Medicine
 Clinical Trials
 Infectious Diseases
 Sports Medicine
   Medical News
 Awards & Prizes
   Special Topics
 Odd Medical News

Last Updated: Oct 11, 2012 - 10:22:56 PM
Research Article
Latest Research Channel

subscribe to Latest Research newsletter
Latest Research

   EMAIL   |   PRINT
Skin cooling associated with increased risk of discoloration after laser treatment

Sep 17, 2007 - 4:00:00 AM
All patients showed less than 25 percent lightening of their Hori nevi at 12 weeks post-treatment. “No difference in clinical improvement was observed regarding the cooling used on one side during treatment,” the authors write.

[RxPG] A cooling technique intended to protect the skin may actually increase the risk of discoloration in dark-skinned patients undergoing laser treatments for mole-like skin lesions, according to a report in the September issue of Archives of Dermatology, one of the JAMA/Archives journals.

Hyperpigmentation, when the skin’s cells increase their production of the brown or black pigment melanin, is the most common adverse effect of laser treatments in dark-skinned individuals, according to background information in the article. “It is not life-threatening, but postinflammatory hyperpigmentation may cause substantial psychological problems,” the authors write. “The treatment of postinflammatory hyperpigmentation is difficult and time-consuming, often lasting many months to achieve the desired results, which causes frustration in patients and physicians.” Some clinicians have hypothesized that skin cooling, which decreases pain and allows the use of higher laser frequencies, could also reduce hyperpigmentation after laser treatment.

Woraphong Manuskiatti, M.D., and colleagues at Mahidol University, Bangkok, Thailand, used laser irradiation (from a 1,064-nanometer Q-switched Nd:YAG laser) to treat 23 Thai women (average age 43) with Hori nevus, blue-brown pigmented spots on the skin that develop later in life. “One randomly selected face side of each patient was cooled using a cold air cooling device during and 30 seconds before and after laser irradiation, and the other side was irradiated without cooling,” the authors write. Two dermatologists not involved in treatment examined digital photographs to measure the occurrence of hyperpigmentation before treatment and one, two, three, four and 12 weeks after treatment.

Of the 21 patients who completed the study, 13 (62 percent) developed hyperpigmentation on the cooled side, five (24 percent) developed it on the uncooled side, one patient (5 percent) developed it on both sides and two (10 percent) did not experience any hyperpigmentation. The cooled sides were three times more likely to become hyperpigmented after laser treatment than the uncooled sides. Most (62 percent) of the cases of hyperpigmentation developed two weeks after treatment, and all but one case completely resolved 12 weeks after treatment.

All patients showed less than 25 percent lightening of their Hori nevi at 12 weeks post-treatment. “No difference in clinical improvement was observed regarding the cooling used on one side during treatment,” the authors write.

It is unclear why cold air cooling would increase the risk of hyperpigmentation following laser treatment, but skin cells may have reacted to the combination of laser treatment and cold air, the authors note. “Future studies should address the question of whether the other methods of epidermal cooling are associated with an increased risk of postinflammatory hyperpigmentation,” they conclude.

Advertise in this space for $10 per month. Contact us today.

Related Latest Research News
Bone loss associated with increased production of ROS
Sound preconditioning prevents ototoxic drug-induced hearing loss in mice
Crystal methamphetamine use by street youth increases risk of injecting drugs
Johns Hopkins-led study shows increased life expectancy among family caregivers
Moderate to severe psoriasis linked to chronic kidney disease, say experts
Licensing deal marks coming of age for University of Washington, University of Alabama-Birmingham
Simple blood or urine test to identify blinding disease
Physician job satisfaction driven by quality of patient care
Book explores undiscovered economics of everyday life
Gene and stem cell therapy combination could aid wound healing

Subscribe to Latest Research Newsletter

Enter your email address:

For any corrections of factual information, to contact the editors or to send any medical news or health news press releases, use feedback form

Top of Page

Contact us

RxPG Online



    Full Text RSS

© All rights reserved by RxPG Medical Solutions Private Limited (India)