RxPG News Feed for RxPG News

Medical Research Health Special Topics World
 Asian Health
 Food & Nutrition
 Men's Health
 Mental Health
 Occupational Health
 Public Health
 Sleep Hygiene
 Women's Health
 Canada Healthcare
 China Healthcare
 India Healthcare
 New Zealand
 South Africa
 World Healthcare
   Latest Research
 Alternative Medicine
 Clinical Trials
 Infectious Diseases
  Anorexia Nervosa
  Child Psychiatry
  Forensic Psychiatry
  Mood Disorders
  Peri-Natal Psychiatry
  Personality Disorders
  Sleep Disorders
  Substance Abuse
 Sports Medicine
   Medical News
 Awards & Prizes
   Special Topics
 Odd Medical News

Last Updated: Oct 11, 2012 - 10:22:56 PM
Smoking Channel

subscribe to Smoking newsletter
Latest Research : Psychiatry : Substance Abuse : Smoking

   EMAIL   |   PRINT
Reviewing evidence for effectiveness of gene-based smoking cessation

Jan 23, 2006 - 5:20:00 PM , Reviewed by: Ankush Vidyarthi
There is also preliminary evidence to support a relationship between eating disorders and smoking, with smoking being used to control weight.

[RxPG] n editorial in the January 2006 issue of the Psychiatric Bulletin reviews the evidence for the effectiveness of gene-based smoking cessation packages, and asks whether they are appropriate for psychiatric patients.

It is well known that the prevalence of smoking among psychiatric patients is far higher than in the general public (70% v. 30%). Smoking in schizophrenia and depression is thought in part to be an attempt to self-medicate symptoms of the illness.

There is also preliminary evidence to support a relationship between eating disorders and smoking, with smoking being used to control weight.

As clinicians working with patients with such high smoking rates, psychiatrists have a duty of care to protect them from the harmful effects of tobacco smoke. This involves informing patients of the best treatment available, and directing them to the appropriate services.

The mainstays of current smoking cessation treatment are nicotine replacement therapy (patches, gum, inhalers, lozenges and spray) and bupropion (Zyban), although behavioural support is also effective.

Gene-based tests for smoking cessation are currently marketed privately to smokers via the internet to help inform them whether they carry gene variants predisposing them to nicotine addiction. The results are given with a personally tailored plan to stop smoking, including medication, behavioural changes and alternative therapies.

Should psychiatric patients be advised to purchase gene-based tests? There are several issues to be considered:

* Genetic association studies are inconclusive with regard to the best genetic candidates in the smoking cessation field
* The responsibilities of general adult psychiatrists, substance misuse service professionals and general practitioners are already significant, without the additional burden of informing themselves about, and providing counselling on, gene-based therapies
* The cost implications for the NHS of this added duty is of concern
* Current privacy laws within the UK fail to protect patients from the misuse of genetic information. Many European countries have laws preventing insurers and prospective employers from gaining access to an individual's genetic profile. When patients spend money on a genetic test for smoking cessation, they are inadvertently generating information about their risk of predisposition to developing or possessing a number of other stigmatising conditions, such as alcohol or cocaine addiction, or pathological gambling
* The majority of people who attempt to give up smoking using genetic tests will fail -success rates are as low as 20% in a year
* Information provided to patients from the test may mislead them into thinking they have a particularly virulent or 'genetic' form of addiction, and are never going to be able to give up.

The authors of the editorial conclude that more research is needed to verify the usefulness of genetic tests for smoking cessation, especially among general medical and psychiatric patients.

Until there is greater understanding of the genetic influences in nicotine addiction, patients being cared for in psychiatric services are best advised to avoid such tests.

Publication: O'Gara C and Munafo M (2006) Psychiatric patients and gene-based smoking cessation packages. Psychiatric Bulletin, 30, 1-2.
On the web: pb.rcpsych.org 

Advertise in this space for $10 per month. Contact us today.

Related Smoking News
Exposure to smoking-cessation product ads helps smokers quit
Want to quit smoking? Therapy and willpower can help
Smokers lose more muscle in old age: study
Children of smokers have more than 5 times higher levels of a nicotine toxin
Nicotine addiction depends on a healthy insula
Knee osteoarthritis more painful for smokers: study
Cutting down cigarettes does not reduce health risk
C. elegans provides model for the genetics of nicotine dependence
Smoking Ban Associated With Rapid Improvement In Health Of Bar Workers in Scotland
Smoking media literacy (SML) is a valuable tool in efforts to discourage teens from smoking

Subscribe to Smoking Newsletter

Enter your email address:

For any corrections of factual information, to contact the editors or to send any medical news or health news press releases, use feedback form

Top of Page

Contact us

RxPG Online



    Full Text RSS

© All rights reserved by RxPG Medical Solutions Private Limited (India)