Vitamin B1 deficiency should be carefully considered after gastric bypass surgery for obesity
Dec 27, 2005 - 5:07:00 PM
, Reviewed by: Rashmi Yadav
|
|
|
"The neurological complications following gastric bypass surgery are diverse. Vitamin B1 deficiency and Wernicke encephalopathy should be carefully considered in surgically treated obese patients."
|
By American Academy of Neurology,
[RxPG] A deficiency in vitamin B1 can be a serious complication following a popular surgery to treat obesity, according to a case study published in the December 27, 2005 issue of Neurology, the scientific journal of the American Academy of Neurology. If untreated, vitamin B1 deficiency can lead to Wernicke encephalopathy, a severe neurological condition.
In the study, a 35-year-old woman developed many difficulties after gastric bypass (bariatric) surgery for obesity. Difficulties included nausea, anorexia, fatigue, hearing loss, forgetfulness, and ataxia, or an inability to coordinate muscle movements. By the 12th week following surgery, she had lost 40 pounds and had difficulty walking and concentrating.
"This case highlights the variability of Wernicke encephalopathy where the classic trio of eye movement abnormalities, confusion, and ataxia are seen in less than 20 percent of patients," said Heidi Schwarz, MD, who wrote a related commentary. "It is unusual because the patient also had hearing loss."
An MRI scan showed abnormal signals in various parts of the woman's brain, indicating a deficiency in vitamin B1. Also known as thiamine, vitamin B1 is essential for carbohydrate metabolism and normal functioning of the nervous system. When her intravenous dose of vitamin B1 was increased to 100 mg every eight hours, her eye muscles gradually returned to normal and her confusion decreased.
Eleven days after her dose of vitamin B1 was increased, a follow-up MRI scan showed the abnormal signals had decreased. The scan also indicated spots in the premotor and motor regions due to hemorrhaging, which is another sign of Wernicke encephalopathy.
"The neurological complications following gastric bypass surgery are diverse," said co-author Raul N. Mandler, MD, a Fellow of the American Academy of Neurology and neurologist at The George Washington University in Washington, D.C. "Vitamin B1 deficiency and Wernicke encephalopathy should be carefully considered in surgically treated obese patients."
Publication:
The study is published in the December 27, 2005 issue of Neurology
On the web:
www.aan.com 
|
Advertise in this space for $10 per month.
Contact us today.
|
 |
|
Subscribe to Surgery Newsletter
|
|
|
|
Additional information about the news article
|
The American Academy of Neurology, an association of nearly 19,000 neurologists and neuroscience professionals, is dedicated to improving patient care through education and research. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as epilepsy, dystonia, migraine, Huntington's disease, and dementia. For more information about the American Academy of Neurology, visit www.aan.com.
Contact: Marilee Tuite
[email protected]
651-695-2789
American Academy of Neurology
|
|
Feedback
|
For any corrections of factual information, to contact the editors or to send
any medical news or health news press releases, use
feedback form
|
Top of Page
|
