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Last Updated: Sep 8, 2007 - 1:21:03 PM |
Latest Research
Depression in women with migraine linked to childhood abuse
ST. PAUL, Minn. – Childhood abuse is more common in women with migraine who suffer depression than in women with migraine alone, according to a study published in the September 4, 2007, issue of Neurology®, the medical journal of the American Academy of Neurology.
Sep 3, 2007 - 4:00:00 AM
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Latest Research
Restless legs genetics on the move
In Germany alone 8 million patients are affected by RLS, which makes it one of the most common neurological diseases. The patients suffer from an urge to move and paresthesia in the legs in the evening and during the night, when they come to rest, which can only be relieved by moving or walking around. The consequence may be severe sleeping disorders, chronic sleep loss and – associated with it – daytime fatigue. In severe cases the disease may lead to depression and social isolation. The frequency of RLS increases with age: up to ten per cent of over 65 year olds are affected, albeit in very different forms. Children can, however, also contract the disease.
Jul 19, 2007 - 4:00:00 AM
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Latest Research
Advice, devices ineffective in preventing worker back pain
Back pain is the number one cause of worker-compensation complaints, second only to the common cold in causing lost workdays. Consequently, employers and regulators have pushed training programs to teach specific lifting methods, and some recommend or require the use of assistive devices such as hoists for hospital workers. However, a new review of the research on lifting advice and handling devices has found that they do not prevent work-related back pain.
Jul 19, 2007 - 4:00:00 AM
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Latest Research
Sports hernia repair surgery plus innovative rehab program helps athletes return to play
St. Louis, July 15, 2007 — In recent years, sports hernias have sidelined many high-level athletes for months and, occasionally, prevented a return to competitive sports all together. New research at Washington University School of Medicine in St. Louis shows that surgical repair of sports hernias using tension-free mesh, coupled with an innovative rehabilitation program, successfully returned athletes to competition in 93 percent of cases.
Jul 15, 2007 - 4:00:00 AM
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Latest Research
Macrochem acquires option to license pexiganan
WELLESLEY HILLS, Mass., July 10 /PRNewswire-FirstCall/ -- MacroChem Corporation (OTCBB: MACM - News) today announced that it has signed an exclusive option to acquire exclusive worldwide license rights for drug uses of pexiganan, a novel, small peptide anti-infective for topical treatment of patients with mild diabetic foot infection (DFI), from Genaera Corporation (Genaera).
Jul 10, 2007 - 4:00:00 AM
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Latest Research
How pain distracts the brain
Anybody who’s tried to concentrate on work while suffering a headache knows that pain compellingly commands attention—which is how evolution helped ensure survival in a painful world. Now, researchers have pinpointed the brain region responsible for pain’s ability to affect cognitive processing. They have found that this pain-related brain region is distinct from the one involved in cognitive processing interference due to a distracting memory task.
Jul 5, 2007 - 4:00:00 AM
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Latest Research
SSRI antidepressants do not pose major birth defect risk
Boston, MA -- Researchers from Boston UniversityÂ’s Slone Epidemiology Center have found that certain selective serotonin reuptake inhibitors antidepressants do not appear to increase the risk for most kinds of birth defects. The findings, to be published in the June 28, issue of the New England Journal of Medicine, suggest that individual SSRIs may increase the risk for some specific defects, but these are rare and the absolute risks are small.
Jun 27, 2007 - 4:00:00 AM
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Latest Research
Community Oncology explores pitched debate over anemia-fighting drugs
The June issue of Elsevier’s Community Oncology takes an in-depth look at the charge that ESAs, generally considered vital to cancer patients’ quality of life, are overprescribed for profit. Scientists, oncologists, and critics of oncologists are in a heated debate now over the use of ESAs, or erythropoiesis-stimulating agents—drugs that fight anemia by boosting levels of oxygen-carrying red blood cells and the protein hemoglobin.
Jun 26, 2007 - 4:00:00 AM
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Latest Research
More than just bare bones -- New research suggests emotions can affect recovery from hip surgery
ST. LOUIS -- A patientÂ’s emotional state plays a significant role in his or her recovery from hip surgery, suggests Saint Louis University research published this month.
Jun 26, 2007 - 4:00:00 AM
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Latest Research
Further legitimization of fibromyalgia as a true medical condition
Philadelphia, June 25, 2007 -- Fibromyalgia, a chronic, widespread pain in muscles and soft tissues accompanied by fatigue, is a fairly common condition that does not manifest any structural damage in an organ. Twenty-five years ago, Muhammad B. Yunus, MD, and colleagues published the first controlled study of the clinical characteristics of fibromyalgia syndrome. That seminal article, published in Seminars in Arthritis and Rheumatism, led directly to formal recognition of this disease by the medical community. In the June 2007 issue of Seminars in Arthritis and Rheumatism, Dr. Yunus once again makes an enormous contribution to the field of chronic pain and fatigue by meticulously synthesizing and interpreting the extensive body of scientific literature on fibromyalgia and his own insights into the concept of central sensitivity syndromes (CSS).
Jun 25, 2007 - 4:00:00 AM
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Latest Research
K-State researcher examining why common anti-inflammatory drugs harm intestines
MANHATTAN, KAN. -- New versions of drugs like buffered aspirin and Vioxx could produce fewer harmful side effects thanks to research being done at Kansas State University's College of Veterinary Medicine.
Jun 21, 2007 - 4:00:00 AM
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Latest Research
Old memory traces in brain may trigger chronic pain
CHICAGO --- Why do so many people continue to suffer from life-altering, chronic pain long after their injuries have actually healed
Jun 4, 2007 - 4:00:00 AM
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Latest Research
Detecting cold, feeling pain: Study reveals why menthol feels fresh
Scientists have identified the receptor in cells of the peripheral nervous system that is most responsible for the body's ability to sense cold.
May 30, 2007 - 4:00:00 AM
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Latest Research
Smokeless cannabis delivery device efficient and less toxic
A smokeless cannabis-vaporizing device delivers the same level of active therapeutic chemical and produces the same biological effect as smoking cannabis, but without the harmful toxins, according to UCSF researchers.
May 15, 2007 - 4:00:00 AM
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Latest Research
Stenting of abdominal arteries offers welcome relief for 'intestinal angina'
(May 11, 2007—ORLANDO, FL)—Using catheter techniques perfected in the arteries of the heart, interventional cardiologists are successfully treating chronic mesenteric ischemia, a condition akin to intestinal angina. According to a study reported at the 30th Annual Scientific Sessions of the Society for Cardiovascular Angiography and Interventions (SCAI), May 9–12, 2007, in Orlando, FL, angioplasty and stenting of clogged arteries in the abdomen successfully restored blood flow to the intestines and relieved painful symptoms in more than 90 percent of patients, without major complications.
May 11, 2007 - 4:00:00 AM
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Latest Research
Counseling, coping skills could reduce arthritis disability
Arthritis sufferers who undergo psychological counseling and learn skills for coping with pain have less disability and better quality of life, according to a new systematic review.
May 10, 2007 - 4:00:00 AM
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Latest Research
BEMA Fentanyl demonstrates substantial transmucosal delivery
Morrisville, North Carolina, May 7, 2007 -- BioDelivery Sciences International, Inc. (Nasdaq:BDSI) announced the results of a 12 subject, crossover study comparing the absorption of fentanyl from both single and multiple BEMA™ Fentanyl discs, as well as oral and intravenous doses of fentanyl. The data demonstrates that the absolute bioavailability (i.e. the total amount absorbed from the delivery system) of fentanyl through the BEMA disc was more than 70%, with 50% absorbed through the buccal mucosa (the inner lining of the cheek). The study further demonstrates that equal doses administered as either a single disc or multiple discs produced nearly identical plasma concentrations (i.e. two 200 mcg discs provided nearly equivalent plasma concentrations as one 400 mcg disc, etc.)
May 7, 2007 - 4:00:00 AM
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Latest Research
Scripps research team sheds light on long-sought cold sensation gene
The discovery, reported in the May 3 issue of the journal Neuron, might one day lead to the development of drugs that induce cold sensation as an analgesic, or block it to prevent certain forms of chronic pain associated with cold sensation.
May 2, 2007 - 4:00:00 AM
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Latest Research
Does execution by lethal injection involve conscious asphyxiation?
Execution by lethal injection may cause death by asphyxiation, and prisoners being executed may be conscious and may experience pain, claim the authors of a new study published this week in PLoS Medicine. Leonidas Koniaris and colleagues from the University of Miami assessed data from two US states that release information on executions together with previously published work on the drugs used in the protocols for lethal injections. They conclude that these protocols may not reliably effect death through the mechanisms intended.
Apr 23, 2007 - 4:00:00 AM
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Latest Research
Did drug reps encourage doctors to prescribe gabapentin for nonapproved uses?
A new study published in PLoS Medicine suggests that so-called detail visits to doctors made by drug company representatives can involve promotion of drugs for non-approved, off-label uses. This may subsequently result in increased prescribing of the drugs for such purposes. Michael Steinman and colleagues from the University of California, San Francisco based their study on visits to doctors made by representatives of the company Parke-Davis between 1995 and 1998 to promote the drug gabapentin.
Apr 23, 2007 - 4:00:00 AM
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Latest Research
Morphine kills the pain, not the patient
Professional and public anxieties about the effects of morphine continue to hinder adequate prescribing of this vital painkiller for genuine pain relief, claims a Comment in this week's edition of The Lancet.
Apr 19, 2007 - 4:00:00 AM
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Latest Research
Tai Chi boosts immunity to shingles virus in older adults, NIH-sponsored study reports
Tai Chi, a traditional Chinese form of exercise, may help older adults avoid getting shingles by increasing immunity to varicella-zoster virus (VZV) and boosting the immune response to varicella vaccine in older adults, according to a new study publishsed in print this week in the Journal of the American Geriatrics Society. This National Institutes of Health (NIH)-funded study is the first rigorous clinical trial to suggest that a behavioral intervention, alone or in combination with a vaccine, can help protect older adults from VZV, which causes both chickenpox and shingles.
Apr 6, 2007 - 4:00:00 AM
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Latest Research
Researchers call for national database of epidural complications
Researchers have called for a national database to be set up to identify major complications arising from epidural pain relief after a small number of serious problems were identified during a six-year UK study, according to the April issue of Anaesthesia.
Apr 2, 2007 - 4:00:00 AM
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Latest Research
MS patients need better socio-economic support as well as medical care
People with multiple sclerosis need much more practical help and better care support, according to a study published in the latest Journal of Advanced Nursing.
Mar 30, 2007 - 4:00:00 AM
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Latest Research
Headache-related work absences have a considerable socio-economic effect
Eight out of ten people who took part in a study carried out by a specialist headache centre felt they were much less effective at work and 91 per cent said they felt hampered by headaches on a daily basis, according to the March issue of Cephalalgia.
Mar 14, 2007 - 4:00:00 AM
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Latest Research
Women need expanded musculoskeletal care during pregnancy, study finds
(Arlington, Va.) -- Despite the high prevalence of musculoskeletal pain during pregnancy, few women in underserved populations receive treatment for their low back pain, according to a February 2007 study in the Journal of Manipulative and Physiological Therapeutics (JMPT). Moreover, researchers found that pain in a previous pregnancy may predict a high risk for musculoskeletal complaints in future pregnancies.
Mar 6, 2007 - 5:00:00 AM
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Latest Research
McGovern Institute Scolnick Prize awarded to David Julius
CAMBRIDGE, MA. Feb 27, 2007 – The McGovern Institute for Brain Research at MIT announced today that David Julius, a physiologist at the University of California at San Francisco (UCSF), will be the 2007 recipient of the Edward M. Scolnick Prize in Neuroscience. The Scolnick prize is awarded each year by the McGovern Institute to recognize an individual who has made outstanding advances in the field of neuroscience. Dr. Julius, who a is a professor and vice chair of the Department of Cellular and Molecular Pharmacology at USCF, receives the 2007 prize for his discovery of the molecular receptors for temperature and inflammatory pain.
Feb 27, 2007 - 5:00:00 AM
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Latest Research
New device safeguards against medication errors at home
CAMDEN -- Patients suffering from chronic illness such as diabetes, congestive heart failure, coronary artery disease, and depression, can take six-to-nine different medications a day – oftentimes more. Skipped doses, misinterpretation or labels, or confusion over what pills to take at what time can be fatal.
Feb 21, 2007 - 5:00:00 AM
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Latest Research
Study finds surfing safer than soccer
Providence, RI -- While public perception may frame surfing as a dangerous sport, new research begs to differ. In the first study of its kind, researchers have computed the rate of injury among competitive surfers and found they are less prone to harm than collegiate soccer or basketball players. Led by researchers at Rhode Island Hospital and Brown Medical School, the findings of the study are published in the January 2007 issue of the American Journal of Sports Medicine.
Jan 2, 2007 - 5:00:00 AM
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Latest Research
Genetic mechanism helps explain chronic pain disorders
CHAPEL HILL - Researchers at the University of North Carolina at Chapel Hill have discovered that commonly occurring variations of a gene trigger a domino effect in chronic pain disorders. The finding might lead to more effective treatments for temporomandibular joint disorder (TMJD) and other chronic pain conditions.
Dec 22, 2006 - 5:00:00 AM
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Latest Research
Psychological treatments improve outcomes for back pain sufferers
Psychological interventions for chronic low back pain are effective, a new review of studies has found. Not only do these approaches improve psychological outcomes such as depression and health-related quality of life, they also reduce patients' experience of pain.
Dec 22, 2006 - 5:00:00 AM
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Latest Research
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Pharmacology
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Analgesics
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Pain Control
Pain control is a mind game
40 pain-free volunteers took part in an experiment funded by the Arthritis Research Campaign using an artificial pain stimulus, and were led to expect reduced pain after the application of a cream which was actually a placebo.
Dec 21, 2006 - 7:39:51 AM
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Latest Research
Pain relief effectiveness down to mind-set?
Research by the Human Pain Research Group at The University of Manchester suggests that people's responses to placebo or 'dummy' pain relief varies according to their way of thinking.
Dec 21, 2006 - 5:00:00 AM
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Latest Research
Workers' compensation ratings don't accurately predict disabilities
CHAPEL HILL -- A study of settlement decisions in workers' compensation claims for low back pain has found almost no relationship between the rating of the disability's severity when the claim was settlement and reported pain and disability 21 months later.
Dec 19, 2006 - 5:00:00 AM
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Latest Research
Study explains how NSAIDs halt cancer growth
BOSTON -- Scientists have discovered that induction of a gene known as MDA-7/IL-24 is the molecular mechanism that enables nonsteroidal anti-inflammatory drugs (NSAIDs) to halt the growth of cancer cells, a finding that could eventually lead to the development of targeted cancer treatments.
Dec 15, 2006 - 5:00:00 AM
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Latest Research
'Best of both worlds' -- Targeting a single gene could inhibit bone decay and stimulate bone growth
(PHILADELPHIA) -- Researchers at the University of PennsylvaniaÂ’s School of Medicine have found by targeting the function of a single gene that it is possible to inhibit bone decay while simultaneously stimulating bone formation. This concept may lead to drug treatments for osteoporosis and other bone diseases. Senior author Yongwon Choi, PhD, professor of Pathology and Laboratory Medicine at the University of Pennsylvania and colleagues report their findings in the December issue of Nature Medicine.
Dec 8, 2006 - 5:00:00 AM
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Latest Research
Origin of inherited pain disorder pinpointed
The genetic basis for a rare inherited disorder that causes severe burning pain with no warning has been pinpointed by researchers. They found that paroxysmal extreme pain disorder (PEPD) is caused by specific mutations in porelike sodium channels in peripheral nerve cells—a discovery that they said emphasizes the role of such channel disorders in inflammatory pain. Such findings of abnormal function in disease also provide insights into the normal function of such channels, they said.
Dec 6, 2006 - 5:00:00 AM
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Latest Research
Low impact aerobic exercise reduces fatigue in auto-immune conditions says multi-study review
Low impact aerobic exercise, such as walking and cycling, can effectively reduce fatigue in adults with chronic auto-immune conditions, according to a research review in the latest issue of the UK-based Journal of Advanced Nursing.
Nov 29, 2006 - 5:00:00 AM
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Latest Research
Hypnosis helps women cope with breast biopsy
CHICAGO -- Radiologists are using an unusual approach, hypnosis, to ease patient pain and anxiety during breast biopsy procedures. A new study from Beth Israel Deaconess Medical Center and Harvard Medical School in Boston found that women who were guided into a state of hypnotic relaxation during biopsy experienced less pain and anxiety during the procedure. The study was presented today at the annual meeting of the Radiological Society of North America (RSNA).
Nov 29, 2006 - 5:00:00 AM
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Latest Research
Spacer insertion may offer less invasive option for lumbar problems
Implanting a small spacer between lumbar vertebrae during a procedure called interspinous process decompression may be an effective and minimally invasive way to treat spinal stenosis, according to a new report.
Nov 28, 2006 - 5:00:00 AM
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Latest Research
Chronic back pain linked to changes in the brain
CHICAGO -- A German research team using a specialized imaging technique revealed that individuals suffering from chronic low back pain also had microstructural changes in their brains. The findings were presented today at the annual meeting of the Radiological Society of North America (RSNA).
Nov 28, 2006 - 5:00:00 AM
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Latest Research
Aching back? Sitting up straight could be the culprit
CHICAGO -- Researchers are using a new form of magnetic resonance imaging (MRI) to show that sitting in an upright position places unnecessary strain on your back, leading to potentially chronic pain problems if you spend long hours sitting. The study, conducted at Woodend Hospital in Aberdeen, Scotland, was presented today at the annual meeting of the Radiological Society of North America (RSNA).
Nov 27, 2006 - 5:00:00 AM
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Latest Research
Enbrel first biologic with up to 9 years rheumatoid arthritis safety, sustained efficacy data
THOUSAND OAKS, Calif., November 12, 2006 -- Amgen (NASDAQ: AMGN) today announced that Enbrel? (etanercept) is the first biologic with published data to show improvements in multiple measures of efficacy that were sustained in rheumatoid arthritis (RA) patients completing up to nine years of therapy. These new data are being presented at the American College of Rheumatology (ACR) Scientific Meeting in Washington, D.C.
Nov 13, 2006 - 5:00:00 AM
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Latest Research
Antioxidants: New kid on the block for pain relief?
COLUMBUS, Ohio -- Antioxidant-based pain killers may one day become a viable alternative to addictive medications such as morphine.
Nov 7, 2006 - 5:00:00 AM
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Latest Research
New biologic treatment for tennis elbow may replace surgery for chronic sufferers
Rosemont, Ill. – October 23, 2006 – A person suffering from tennis elbow may not have to look any further than his or her own body for the most effective treatment, according to a study published in the November issue of The American Journal of Sports Medicine.
Oct 23, 2006 - 4:00:00 AM
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Latest Research
Molecule discovered to be key to pain sensitivity
Sensitivity to pain and the risk of developing chronic pain appear to be influenced by levels of a molecule known to be required for the production of major neurotransmitters. In the November issue of Nature Medicine, an international research team based at Massachusetts General Hospital (MGH) describes this unexpected role for the molecule called BH4 and their findings that a particular set of variations in a human gene involved in synthesizing the molecule appears to reduce pain sensitivity.
Oct 22, 2006 - 4:00:00 AM
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Latest Research
Gene variation affects pain sensitivity and risk of chronic pain
A new NIH-funded study shows that a specific gene variant in humans affects both sensitivity to short-term (acute) pain in healthy volunteers and the risk of developing chronic pain after one kind of back surgery. Blocking increased activity of this gene after nerve injury or inflammation in animals prevented development of chronic pain.
Oct 22, 2006 - 4:00:00 AM
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Latest Research
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Pharmacology
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Analgesics
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Pain Control
Prescription pain medication abuse on rise
Researchers at Rush University Medical Center found prescription pain medication (PPM) abuse is a rapidly growing problem with surprising and often unpredictable distribution patterns. The research was presented at the Annual Meeting of the American Society for Anesthesiologists in Chicago, October 13, 2006.
Oct 17, 2006 - 2:16:00 AM
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Latest Research
New study reveals postcode lottery for rheumatoid arthritis treatment
New research published in the medical journal Rheumatology [1] today (11 October 2006) reveals that, despite the National Institute for Health and Clinical Excellence (NICE) approving anti-tumour necrosis factor alpha (TNF) therapy for RA in 2002, many primary care trusts are refusing to fund it adequately or are putting a cap on the numbers of patients that can be treated.
Oct 11, 2006 - 4:00:00 AM
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Latest Research
Spinal cord stimulators tested as treatment for patients with migraine headaches
Researchers at Rush University Medical Center are testing a new treatment for migraine headaches: occipital nerve stimulation, a surgical procedure in which an implanted neurostimulator delivers electrical impulses to nerves under the skin at the base of the head at the back of the neck.
Sep 27, 2006 - 4:00:00 AM
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