RxPG News Feed for RxPG News

Medical Research Health Special Topics World
  Home
 
   Health
 Aging
 Asian Health
 Events
 Fitness
 Food & Nutrition
 Happiness
 Men's Health
 Mental Health
 Occupational Health
 Parenting
 Public Health
 Sleep Hygiene
 Women's Health
 
   Healthcare
 Africa
 Australia
 Canada Healthcare
 China Healthcare
 India Healthcare
 New Zealand
 South Africa
 UK
 USA
 World Healthcare
 
   Latest Research
 Aging
 Alternative Medicine
 Anaethesia
 Biochemistry
 Biotechnology
 Cancer
 Cardiology
 Clinical Trials
 Cytology
 Dental
 Dermatology
 Embryology
 Endocrinology
 ENT
 Environment
 Epidemiology
 Gastroenterology
 Genetics
 Gynaecology
 Haematology
 Immunology
 Infectious Diseases
 Medicine
 Metabolism
 Microbiology
 Musculoskeletal
 Nephrology
  Dialysis
 Neurosciences
 Obstetrics
 Ophthalmology
 Orthopedics
 Paediatrics
 Pathology
 Pharmacology
 Physiology
 Physiotherapy
 Psychiatry
 Radiology
 Rheumatology
 Sports Medicine
 Surgery
 Toxicology
 Urology
 
   Medical News
 Awards & Prizes
 Epidemics
 Launch
 Opinion
 Professionals
 
   Special Topics
 Ethics
 Euthanasia
 Evolution
 Feature
 Odd Medical News
 Climate

Last Updated: Oct 11, 2012 - 10:22:56 PM
Research Article
Nephrology Channel

subscribe to Nephrology newsletter
Latest Research : Nephrology

   EMAIL   |   PRINT
Bone mineral density loss faster in those with kidney disease

Feb 6, 2010 - 3:20:32 PM , Reviewed by: Dr. Sanjukta Acharya
“Our findings highlight the importance of estimating kidney function when evaluating patients for fracture risk,” Sophie A. Jamal, MD, PhD

***image1***
 
[RxPG] Even slight kidney impairment can speed up the loss of bone mineral density (BMD) among older people, putting them at risk of potentially disabling fractures, new research shows.

“Our findings highlight the importance of estimating kidney function when evaluating patients for fracture risk,” Sophie A. Jamal, MD, PhD, of the University of Toronto and her colleagues say in the February issue of the American Journal of Kidney Diseases, the official journal of the National Kidney Foundation.

Most people who have chronic kidney disease (CKD), or who are at risk for this condition, don’t know it, points out Dr. Kerry Willis, senior vice president for scientific activities at the National Kidney Foundation. “The new findings show the potential impact of early identification of kidney disease in preventing complications that can cause disability and premature death,” Dr. Willis said.

When a person’s kidney function is completely lost—a condition known as end-stage renal disease—he or she is at much greater risk of sustaining a hip fracture, Dr. Jamal and her colleagues explain in their report.

To better understand the relationship between more modest kidney impairment and bone loss, the researchers followed 191 men and 444 women age 50 and older for five years. They used two different techniques—estimated creatinine clearance and estimated glomerular filtration rate—to gauge patients’ kidney function at the beginning of the study. The first test measures how quickly the kidneys clear creatinine (a waste product), from the blood, and the second gauges the speed at which fluid flows through the kidney. Study participants also had their BMD measured at the beginning of the study and five years later.
Dr. Jamal and her team found that the people with impaired kidney function lost BMD faster than those whose kidneys were working normally. For example, the study participants with the worst kidney function showed a 9.3 percent greater decrease in their lower spine BMD over a five-year period compared to those with normally functioning kidneys. The results were basically the same with either kidney function measure.

“Not only is this a substantial loss, but equally concerning is that the bone loss occurs with even modest impairment of kidney function,” Dr. Jamal and her colleagues say.

To date, the National Kidney Foundation’s Kidney Early Evaluation Program (KEEP) has screened 130,000 high-risk individuals for CKD, Dr. Willis said. Anyone 18 and older who has high blood pressure, diabetes or a family history of kidney disease should be screened for CKD, she added, which can be done with three simple tests: blood pressure measurement, a urine test for the presence of a protein called albumin, and a blood test for creatinine.

“Osteoporosis can lead to potentially disabling fractures of the spine and hip,” she added. “Physicians should understand that even a slight decline of kidney function in their older patients could mean an increased risk of osteoporosis.”



Publication: February issue of the American Journal of Kidney Diseases

Advertise in this space for $10 per month. Contact us today.


Related Nephrology News
Renal biomarkers predict risk of acute kidney injury following surgery in two large studies
Intradialytic hypotension associated with increased incidence of haemodialysis vascular access thrombosis
Mouse model shows that kidney-specific dopamine system important for kidney function and blood pressure regulation
Blood pressure control system in distal nephron
Adherence to cardiac medication less in renal patients
Higher Leptin levels associated with lower bone turnover in Renal transplant patients
Vegetarian diets help renal patients to lower serum phosphorus and FGF-23 levels
SHARP trial shows benefit of cholesterol-lowering in Chronic Kidney Patients
Low Phosphate diet not helpful in dialysis patients
Poor kidney function in HIV- infected drug users

Subscribe to Nephrology Newsletter

Enter your email address:


 About Dr. Sanjukta Acharya
This news story has been reviewed by Dr. Sanjukta Acharya before its publication on RxPG News website. Dr. Sanjukta Acharya, MBBS MRCP is the chief editor for RxPG News website. She oversees all the medical news submissions and manages the medicine section of the website. She has a special interest in nephrology. She can be reached for corrections and feedback at sanjukta.acharya@rxpgnews.com
RxPG News is committed to promotion and implementation of Evidence Based Medical Journalism in all channels of mass media including internet.
 Feedback
For any corrections of factual information, to contact the editors or to send any medical news or health news press releases, use feedback form

Top of Page

 
Contact us

RxPG Online

Nerve

 

    Full Text RSS

© All rights reserved by RxPG Medical Solutions Private Limited (India)