RxPG News Feed for RxPG News

Medical Research Health Special Topics World
 Asian Health
 Food & Nutrition
 Men's Health
 Mental Health
 Occupational Health
 Public Health
 Sleep Hygiene
 Women's Health
 Canada Healthcare
 China Healthcare
 India Healthcare
 New Zealand
 South Africa
 World Healthcare
   Latest Research
 Alternative Medicine
 Clinical Trials
 Infectious Diseases
  Anorexia Nervosa
  Child Psychiatry
  Forensic Psychiatry
  Mood Disorders
  Peri-Natal Psychiatry
  Personality Disorders
  Sleep Disorders
  Substance Abuse
 Sports Medicine
   Medical News
 Awards & Prizes
   Special Topics
 Odd Medical News

Last Updated: Oct 11, 2012 - 10:22:56 PM
The Journal of Clinical Pharmacology Suicide Channel

subscribe to Suicide newsletter
Latest Research : Psychiatry : Suicide

   EMAIL   |   PRINT
Antidepressants are of questionable benefit in teenage suicide cases

Sep 14, 2006 - 5:01:00 PM , Reviewed by: Ankush Vidyarthi
"The short duration of depressive symptoms in this age group makes it difficult to distinguish drug efficacy from placebo."

[RxPG] There has been much controversy in recent years regarding the correlation between teenage suicide and the use of antidepressant drugs. At an FDA meeting reviewing this topic, the majority of clinical trials examined did not show that the drugs were effective in treating depression in children and adolescents.

In a recent study published in the September issue of the Journal of Clinical Pharmacology, Dr. Richard Malone, from the Department of Psychiatry at Drexel University College of Medicine and Philadelphia Health & Education Corporation, and colleagues suggest that the short duration of depressive symptoms in this age group makes it difficult to distinguish drug efficacy from placebo.

Using a naturalistic study design, the researchers advise using multiple assessments to establish a continuous baseline before randomizing patients to treatment, which would remove those who spontaneously recover in a very short period of time. In addition to having an impact on the accuracy of future clinical trials, this approach may help decrease the number of children who are exposed to unnecessary long-term drug therapy and possible side effects, since those who spontaneously recover quickly would not be started on drug therapy.

The article "Impersistence of Depression in Youth: Implications for Drug Study Design" can be accessed at no-charge for a limited time at The Journal of Clinical Pharmacology's web site.

Publication: The study is published in the September issue of the Journal of Clinical Pharmacology
On the web: The Journal of Clinical Pharmacology 

Advertise in this space for $10 per month. Contact us today.

Related Suicide News
Understanding gender differences in suicide methods
Countries with high happiness levels also have high suicide rates
More than half college students have suicidal thoughts
Sleep disturbances among the elderly linked to suicide
Genetic variations may predispose some men to suicidal thoughts during treatment for depression
Sleep disorder may cause suicidal tendencies
Suicide rate among NY's ethnic women population alarming
Suicide Risk associated with Pre- and Postnatal and Early Childhood Factors
Antidepressants are of questionable benefit in teenage suicide cases
Cancer survivors at risk for suicidal thoughts

Subscribe to Suicide Newsletter

Enter your email address:

 Additional information about the news article
About The Journal of Clinical Pharmacology (JCP)

For over 45 years, clinical pharmacologists, clinical and pharmaceutical researchers, drug development specialists, physicians, nurses, and other medical professionals have relied on The Journal of Clinical Pharmacology for original research, special reviews, commentaries, and case reports on all phases of drug development. One of the most highly cited journals in the field, it features up to-the-minute and pertinent clinical information about the safety, tolerability, efficacy, therapeutic applications, toxicology, and total evaluation of new and established drugs for humans. JCP is the official journal for the American College of Clinical Pharmacology. www.jclinpharm.org

About SAGE

SAGE Publications is a leading international publisher of journals, books, and electronic media for academic, educational, and professional markets. Since 1965, SAGE has helped inform and educate a global community of scholars, practitioners, researchers, and students spanning a wide range of subject areas including business, humanities, social sciences, and science, technology and medicine. SAGE Publications, a privately owned corporation, has principal offices in Thousand Oaks, California, London, United Kingdom, and New Delhi, India. www.sagepublications.com

For any corrections of factual information, to contact the editors or to send any medical news or health news press releases, use feedback form

Top of Page

Contact us

RxPG Online



    Full Text RSS

© All rights reserved by RxPG Medical Solutions Private Limited (India)