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Last Updated: Sep 13, 2008 - 5:00:44 PM |
Latest Research
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Haematology
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Thalassemias
Alpha-Thalassemia and Protection from Malaria
Over the course of human history, hundreds of thousands of genetic mutations have arisen in the global population. The most harmful ones usually disappearby affecting an individual's fitness, i. e., the ability to reproduce, the mutations are lost before carriers can pass them on to their childrenwhereas most mutations are maintained in the population in low frequencies. Some mutations, however, can give the carrier such a large survival advantage that the mutations become positively selected for, leading to their presence in high frequencies in some populations.
Apr 21, 2006 - 12:37:00 AM
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Latest Research
:
Haematology
:
Thalassemias
MBD2 Protein mediates silencing of the fetal gamma-globin gene through DNA methylation
Virginia Commonwealth University Massey Cancer Center researchers have identified the role of a protein in hemoglobin gene silencing that may one day be a potential target for the treatment of genetic blood disorders like sickle-cell anemia and beta-thalassemia on the molecular level.
Apr 11, 2006 - 10:42:00 PM
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