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Latest Research : Cancer : Brain Last Updated: Nov 17th, 2006 - 22:35:04

Latest Research : Cancer : Brain
Regulatory Approval for New Cotara(R) Brain Cancer Clinical Trial
Peregrine Pharmaceuticals, Inc. (Nasdaq: PPHM), a biopharmaceutical company with a portfolio of innovative, clinical stage products for the treatment of cancer and hepatitis C virus infection, today announced that it has received regulatory approval in India for a new clinical trial of its lead tumor necrosis therapy (TNT) agent Cotara(R). The trial is designed to test the safety and efficacy of Cotara in patients with glioblastoma multiforme, a deadly form of brain cancer. Cotara is currently being studied in a multi-center U.S. glioblastoma trial. Previous studies using Cotara to treat brain cancer have produced encouraging results, and Peregrine expects that positive data from this trial in combination with data from the ongoing U.S. clinical trial should provide the foundation for planning the future development and commercialization of Cotara.
Oct 13, 2006, 01:17

Latest Research : Cancer : Brain
Lead exposure linked with brain cancer
People who are routinely exposed to lead on the job are 50 percent more likely to die from brain cancer than people who are not exposed, according to a University of Rochester Medical Center study.
Aug 29, 2006, 03:13

Latest Research : Cancer : Brain
Synthetic scorpion venom delivers radioactive iodine to malignant gliomas
A new method of delivering a dose of radioactive iodine � using a man-made version of scorpion venom as a carrier � targets deadly brain tumors called gliomas without affecting neighboring tissue or body organs. After a Phase I clinical trial conducted in 18 patients showed the approach to be safe, a larger Phase II trial is underway to assess the effectiveness of multiple doses.
Jul 30, 2006, 02:45

Latest Research : Cancer : Brain
Chromosomal Testing Can Determine Brain Tumor Therapy
A trial involving two types of rare, malignant but treatable brain tumors shows that missing portions of two chromosomes can predict which patients will likely do better with therapy. The results, says senior author Walter J. Curran Jr., M.D., professor and chair of radiation oncology at Jefferson Medical College of Thomas Jefferson University in Philadelphia, represents a paradigm shift in treating such tumors, known as gliomas.
Jul 1, 2006, 03:39

Latest Research : Cancer : Brain
Motexafin gadolinium extends cognitive function in patients with brain metastases
The drug motexafin gadolinium (Xcytrin�), based on a molecule developed by chemists at The University of Texas at Austin, shows significant promise in prolonging cognitive function in patients with non-small cell lung cancer that has metastasized to the brain.
Jun 6, 2006, 14:44

Latest Research : Cancer : Brain : Glioblastoma Multiforme
New vaccine to fight glioblastoma multiforme developed
A vaccine to fight an aggressive form of brain tumour has been developed by US scientists, who say it can delay progression of the cancer.
May 2, 2006, 22:40

Latest Research : Cancer : Brain : Medulloblastoma
New mouse model that closely mimics human medulloblastoma
Researchers have created a mouse model that closely mimics human medulloblastoma, the most common type of childhood brain tumor. The new model, which was created by knocking out a key component of the DNA repair machinery, will aid in exploring the genetic roots of this deadly brain cancer. The researchers, led by Howard Hughes Medical Institute investigator Frederick W. Alt, published their findings the week of April 24, 2006, in the early online edition of the Proceedings of the National Academy of Sciences. Catherine Yan, who is in Alt's laboratory at Children's Hospital Boston, was lead author of the article. Other co-authors were from Brigham & Women's Hospital, CBR Institute of Biomedical Research, Children's Hospital and Dana-Farber Cancer Institute, all of Harvard Medical School.
Apr 28, 2006, 01:38

Latest Research : Cancer : Brain
Immune response protects against brain tumor development
In their quest to determine whether immune system surveillance guards against brain tumor development, researchers at The University of Texas M. D. Anderson Cancer Center have found that allergies and asthma that stimulate inflammation may be protective, but use of antihistamines to control the inflammation could eliminate that protection.
Apr 3, 2006, 07:02

Latest Research : Cancer : Brain
Long mobile use could cause brain tumours - New Study
Using a cell phone for long periods could lead to malignant brain tumours, says a new study contradicting earlier findings which found no such link.
Apr 3, 2006, 07:01

Latest Research : Cancer : Brain
Donepezil helps cognitive function in brain tumor patients after radiation
A drug that is marketed to treat Alzheimer's disease also improves cognitive function, mood and quality of life in brain tumor patients following radiation therapy, according to a research team at Wake Forest University Baptist Medical Center.
Mar 19, 2006, 20:50

Latest Research : Cancer : Brain
Infections could trigger some adult brain tumours
Infections could play a key role in triggering certain types of adult brain cancer, according to results from a new statistical analysis of the disease.
Jan 24, 2006, 15:54

Latest Research : Cancer : Brain
Mobiles not linked to increased risk of brain tumours
Mobile phones are not associated with an increased risk of the most common type of brain tumour, finds the first UK study of the relationship between mobile phone use and risk of glioma. The results are published online by the BMJ.
Jan 21, 2006, 16:21

Latest Research : Cancer : Brain
No link between mobile phones and glioma
Mobile phones are not associated with an increased risk of the most common type of brain tumour, finds the first UK study of the relationship between mobile phone use and risk of glioma. The results are published online by the BMJ today.
Jan 20, 2006, 15:14

Latest Research : Cancer : Brain : Glioblastoma Multiforme
Discovery could change the way doctors treat glioblastomas
Researchers at UCLA's Jonsson Cancer have identified key characteristics in certain deadly brain tumors that make them 51 times more likely to respond to a specific class of drugs than tumors in which the molecular signature is absent. The discovery of the telltale molecular signature � the expression of a mutant protein and the presence of a tumor suppressor protein called PTEN � will allow researchers to identify patients who are likely to respond to the drug treatment before they undergo therapies that are not likely to work, said Dr. Paul Mischel, a UCLA associate professor of pathology and laboratory medicine and a Jonsson Cancer Center researcher.
Nov 11, 2005, 00:46

Latest Research : Cancer : Brain : Glioblastoma Multiforme
Glioblastoma Gene Variations Can Predict Treatment Response
Screening glioblastoma brain tumors for two gene variations can reliably predict which tumors will respond to a specific class of drugs, a new study shows. The findings may lead to improved treatment for this devastating disease. The study was funded in part by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), and appears in the November 10, 2005, issue of the New England Journal of Medicine. Glioblastomas are the most common malignant brain tumors in adults, and they are notoriously difficult to treat successfully. "The survival with glioblastoma is usually a year on average, and that hasn't improved in a while, so this is a very serious and challenging disease," says Paul Mischel, M.D., of the David Geffen School of Medicine and Jonsson Comprehensive Cancer Center at the University of California , Los Angeles (UCLA), who led the study. While drugs are available to help treat glioblastoma, they often have minimal effect, and doctors usually have time to try only one or two treatments before the disease causes severe impairment. Glioblastomas feature many genetic variations that affect their response to different treatments. Researchers are trying to identify these genetic factors and to tease apart how they affect the disease in order to determine which patients are the most likely to benefit from specific drugs.
Nov 11, 2005, 00:20

Latest Research : Cancer : Brain
Evidence-based Review on Radiation for Brain Tumors
The American Society for Therapeutic Radiology and Oncology gathered a panel of experts to compile and analyze existing studies on the use of radiosurgery, a specialized type of external beam radiation therapy that pinpoints high doses of radiation to treat brain tumors. The panel has developed evidence-based reviews that consolidate the information available and identify questions to be answered in future research. The two new reviews are published in the September 1, 2005 issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of ASTRO.
Sep 11, 2005, 21:41

Latest Research : Cancer : Brain : Glioblastoma Multiforme
P-gp system let JV-1-36 pass into the brain to treat malignant glioblastomas
A compound that kills cancer can sneak past the blood brain barrier, which protects the brain from foreign substances, to do its work in fighting a particularly invasive brain cancer, according to a new Saint Louis University animal study published in the Proceedings of the National Academy of Sciences Online Early Edition the week of Aug. 22.
Aug 23, 2005, 19:56

Latest Research : Cancer : Brain : Glioblastoma Multiforme
Combined gene therapy can eliminate glioblastoma multiforme
Despite aggressive treatment, glioblastoma multiforme (GBM) � the most common and deadly of brain cancers � usually claims the lives of its victims within six to 12 months of diagnosis. Because GBM is so aggressive, the disease has been the target of a number of laboratory and clinical studies investigating the effectiveness of gene therapy to deliver novel therapies to the brain. In laboratory studies, this type of gene therapy has proved almost completely effective. But in clinical trials, it has had limited effectiveness.
Aug 15, 2005, 17:44

Latest Research : Cancer : Brain
Vaccine to target resistance-related antigen in Brain tumours
In the August issue of the journal Oncogene, researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute describe a molecular mechanism that appears to make malignant brain tumors more vulnerable to chemotherapy after they have been treated with the dendritic cell vaccine.
Jun 14, 2005, 06:24

Latest Research : Cancer : Brain
First Study to Prove association of Mobile Phones with Brain Tumours
The findings are based on a sample of over 1400 adults aged between 20 and 80, living in the centre of Sweden. All of them had been diagnosed with a malignant or benign brain tumour between January 1997 and June 2000.
May 18, 2005, 14:55

Latest Research : Cancer : Brain
Chromosome Deletion Predicts Outcome in Neuroblastoma Patients
Researchers from the Children's Hospital of Philadelphia and the Children's Oncology Group found that patients with neuroblastoma who are missing a portion of one of their chromosomes are less likely to survive than those without this genetic aberration, providing potentially important information to guide therapy.
May 18, 2005, 01:45

Latest Research : Cancer : Brain
Pituitary Gland Tumors Are Often Misdiagnosed
A recent study found that tumors of the pituitary gland are more common than many health care professionals realize, with national prevalence rates averaging 16.7 percent.
May 1, 2005, 21:04

Latest Research : Cancer : Brain
CHMP Issues Positive Opinion for First-line Use of Temozolomide in the treatment of Glioblastoma Multiforme
Schering-Plough Corporation (NYSE: SGP - News) today reported that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMEA) has issued a positive opinion recommending approval of TEMODAL� (temozolomide) Capsules for first-line use in the treatment of patients with newly diagnosed glioblastoma multiforme (GBM), the most common form of brain cancer. The CHMP recommendation serves as the basis for a European Commission approval.
Apr 24, 2005, 08:22

Latest Research : Cancer : Brain
No Link Between Cell Phone and Brain Tumors
A new study has found no link between use of cell phones and the risk of developing a brain tumor.
Apr 12, 2005, 18:02

Latest Research : Cancer : Brain
Viruses May Treat Brain Tumors
New research shows that a virus designed to kill cancer cells can significantly increase the survival of mice with an incurable human brain tumor, even in some animals with advanced disease.
Apr 8, 2005, 01:36

Latest Research : Cancer : Brain
Errant neuro-developmental gene implicated in brain cancer
A gene that's normally silenced after contributing to brain development was found to be expressed in cells from medulloblastoma, the most common form of pediatric brain malignancy in children, scientists report in an article published in the February 1 issue of the journal Cancer Research. In their study, the scientists discovered that multiple extra copies of the gene, called OTX2, had been switched back on among tumor cells removed from patients with medulloblastoma brain tumors. In the United States, medulloblastoma accounts for approximately 30 percent of all pediatric brain tumors.
Feb 3, 2005, 00:49


Headlines
Latest Research
Phase Ib Trial Is Evaluating Bavituximab Administered With Common Chemotherapy Regimens
Treatment with hormones improves visual memory of postmenopausal women
Sleep Apnea Treatment Curbs Aggression in Sex Offenders
Occupational therapy improves quality of life for dementia patients
Gene Expression Profiling Not Quite Perfected in Predicting Lung Cancer Prognosis
Scientists design simple dipstick test for cocaine, other drugs
British scientists create artificial stomach
Pregnant women with lupus are at higher risk for complications
Memories: It's all in the packaging
Seven-point system gauges seriousness of heart failure in elderly
New Effort to Treat Stroke More Effectively
Keeping A3G in action represents a new way to attack HIV
Fighting HIV With HIV Virus Itself
Children�s Belly Fat Increases More Than 65 Percent
Common Antacids Could Help Keep Gingivitis at Bay
New way of tracking muscle damage from radiation
New brain-chemistry differences found in depressed women
Retina can provide a very reliable way of diagnosing cerebral malaria
Hormone therapy does not improve quality of life for women
Anxiety sensitivity linked to future psychological disorders
Rising abdominal obesity among kids causes concern
How cells adhere so firmly to blood vessel walls
Cot death could be linked to brain defect
C. elegans provides model for the genetics of nicotine dependence
Resveratrol Increases Lifespan of Obese Mice
Uric acid levels closely related to hypertension in Blacks
Predicting survival in liver transplant patients
American College of Cardiology announces new initiative to improve safety for patients with Acute Coronary Syndromes
Two-component lantibiotic with therapeutic potential discovered
Hope remains for Alzheimer's sufferers
New Insight into Cell Division
Breast cancer chemotherapy may deterioration in cognitive function
Many adults with psychiatric disorders may also have undiagnosed ADHD
Lisdexamfetamine dimesylate (NRP104/LDX) is generally well-tolerated.
Cognitive Decline is Often Undetected - Study
Are influenza vaccines worth the effort?
Researchers find a gene variant that protects against development of IBD
New research into csd genes could help designing strategies for breeding honey bees
Is TROPHY misleading?
I-ELCAP study: Lung cancer can be detected early with annual low-dose CT screening
A light daily exercise program may reduce the incidence of colds
Atrial Fibrillation linked to Reduced Cognitive Performance
Genomic signatures to guide the use of chemotherapeutics
Anxiety Disorders and Physical Illness
Human Memory Gene Identified
Making the connection between a sound and a reward changes behavioral response
Medical induction of labor increases risk of amniotic-fluid embolism
Researchers Create First Working Invisibility Cloak
Laser Analysis Points to Brain Pigment's Hidden Anatomy
Link between short sleep duration and obesity uncovered
Medical News
Google could help diagnose difficult medical cases
Overseas Doctors hit by new British HSMP immigration rules
Mental health problems threaten the knowledge economy
Indians among worst affected by TB in Britain
Bihar to get eight new private medical colleges
Future of sexual and reproductive health at tipping point according to global study
Profiles of serial killers have limitations
Concerns over abortion law in the US state of South Dakota
European Alcohol Strategy Threatened by Industry Tactics
Raine Study: Breastfeeding boosts mental health
Severe discrimination based on race and ethnicity in medical-school admissions at University of Michigan
Small But Substantial Proportion Of Surgical Residents Interested In Part-Time Training
Lawrence Berkeley National Laboratory Opens the National Center for X-ray Tomography (NCXT)
States That Easily Grant Immunization Exemptions Have Higher Incidence Of Whooping Cough
The need for "exercise prescriptions."
Robot wheelchair may give patients more independence
Study calls for 39 percent more family physicians in USA
Sleep-related breathing disorder can increase risk of depression
Mandarin oranges decrease liver cancer risk,atherosclerosis
The future of plastic surgery
Parents drink, Suffer the Children
University of Pittsburgh to host Global Health Conference
EMCare now available via Dialog and Datastar
IOF to launch 'Bone App�tit' campaign on October 20
Mental health units should not be exempt from smoking ban
Fewer Girls Under China's One Child Policy
Online video games found to promote sociability
Community model effective in allotting anti-AIDS medication
FDA safety alerts for automated external defibrillators occur frequently
Conjoined American twins separated
Young teens see pregnancy as a way to enhance relationships
Increased understanding of what helps or hinders disclosure could help patients
Food labels should list trans fats to help reduce coronary heart disease
NHS may be buying surgical equipment unethically
Is it time to give NHS more independence?
A mother's attentiveness to baby's distress is important
University of Leeds receives Gates Foundation grant for material approach to malaria prevention
Indian scientists develop Elisa tests for avian influenza
High Common Daily Activity Levels Reduce Risk Of Death
How Group Dynamics Affect Fitness and Eating Habits
DDT in moms harmful to kids, study
Ultraviolet radiation from sunbeds increases skin-cancer risk
Drug approval processes may have delayed warnings about safety of Paroxetine
Tuberculosis control and impact of socially excluded groups
Pertussis Endemic Among UK School Children
Building a safer NHS: How safe are the patients?
Hospital Performance Results Do Not Always Reflect Patient Outcomes
EPICURUS: Job satisfaction is the most critical factor for life satisfaction
Humans could learn a lot from ants
A Placebo a Day, Keeps the Doctor Away
Careers
Certification of UK doctors would improve quality of care
Exam nerves affects students' immune defence
Jefferson Acquires Wills Eye Residency Programs
Hyderabad ISB student offered 10 million annual pay
Work permit rule hits Indian doctors in Britain
JIPMER Pondicherry set for revamp
Factors in religious sensitivity for medical students
AMA Sets Out Strategy To Get More Doctors Working in Rural and Regional Australia
NHS dentists increased by 1,100 in a year
Major Increase in U.S. Medical School Enrollment
Revised GRE� General Test to Premiere in October 2006
Birrell Report Reflects AMA Recommendations on OTD Assessment
World�s First Internet-Based English-Proficiency Test
Low numbers of state school students enter medical school
Renewed interest in young physicians to pursue research careers
States Must Increase Advanced Surgical Training (AST) Places
Women doctors and their careers: what now?
Number Of Students In U.S. Medical Schools Remains Constant
Record Number Of Trainee Residents And Fellows In US
Foundation Trust Network reaches historic agreement with Royal Colleges
On Call Induced Intoxication in Junior Doctors - Research
Royal College of General Practitioners announces GP certification unit
Second Counseling Breakthrough for All India Medical PG Seats
Stop Passing the Buck on Surgical Training
Virtual Celebration Encourages Exploration of Genomic Careers
Survey Of 76,000 Nurses Probes Elements Of Job Satisfaction
Washington University School of Medicine in St. Louis ranked 3rd in U.S.
New Junior Doctor Training Curriculum Launched
Kalam's Clarion call to the Young Scientists to become Continuous Innovators
JCHMT assessment tools are now available
Indian Health Minister Visits AIPGE Counseling Center
EEA Doctors to face Pre-Registration Identity Checks in UK
Surgical Training in UK seriously compromised by EWTD
Supreme Court of India sought information about numbers of All India Medical Post Graduate (PG) Seats
Shortfall predicted in number of surgeons in UK
Overseas doctors are finding it difficult to get jobs in UK
Overseas junior doctors warned to expect unemployment in the UK
New GMC guidance for Pre Registration House Officer (PRHO) training
RCGP conference on GP appraisal
Extra exam sessions of IQE to speed up overseas dental recruits
Discussion of Step 2 CS Case Content is Irregular Behavior
Special Topics
New approach will pinpoint genes linked to evolution of human brain
Accelerating Loss of Ocean Species Threatens Human Well-being
New genetic analysis forces re-draw of insect family tree
Cell Phone Use Associated with Decline in Fertility
Marijuana-like Chemical Can Restore Sperm Function Lost to Tobacco Abuse
Reporters struggle to cover comas in newspaper articles
Drug Company Research Reports Should Be Read With Caution
Giant insects might reign if only there was more oxygen in the air
Infection Status Drives Interspecies Mating Choices in Fruit Fly Females
Waiting For Trial Results Sometimes Unethical
NHGRI Funds Assessment of Public Attitudes About Population-Based Studies on Genes and Environment
Mother birds give a nutritional leg up to chicks with unattractive fathers
Mammals Evolve Faster on Islands!
A Bacterial Protein Puts a New Twist on DNA Transcription
Physicians More Likely To Disclose Medical Errors That Would Be Apparent To The Patient
Dissecting Doctor Patient Dialogue
Why Does Sex Exist?
Pseudogenes Research Reinforces Theory of Evolution
Non-human primates may be linchpin in evolution of language
Primates developed close-up eyesight to avoid a dangerous predator
Doctors inadvertently help terminally ill patients to die sooner
Parsing the Functional Fields of the Auditory Cortex
Declining Human Fertility is Evolutionary Adaptation
Study shows that threat displays may prevent serious physical harm
How animals learn from each other
Thermal Adaptation in Bacterial Viruses
Genetic quality of sperm worsens as men get older
Songbirds boost size of eggs when hearing sexy song
Small naps a big help for young docs on long shifts
Why women live longer than men
Indian medical students protest quota policy across the country
VitaCig - Cigarettes with Vitamin C that don't stain teeth
Indian scribe pleads for mercy killing
A sneeze could give away your personality traits
Two-week-old embedded arrow surgically removed
Fruitfly study shows how evolution wings it
Woman delivers baby on road in West Bengal
Tantalizing clue to the evolutionary origins of light-sensing cells
Relationship of brain and skull more than just packaging
Restoring virtue for Rs.20,000!
Responsibility in gambling?
Living with boyfriend? You could become obese
Children's Viewing Time May Increase Requests For Advertised Products
Researchers And Parents Should View Media As A Public Health Issue
Zugunruhe! Resident Birds Display Migratory Restlessness
What Does Evolution Do with a Spare Set of Genes?
Value of services provided by insects is $57 billion in U.S.
British student to investigate dogs' barks
Two foetuses removed from 45-day-old baby
Evolutionary biology research techniques predict cancer
World News
Tomatoes in Restaurants Linked to Salmonella Typhimurium Outbreak
Are Flu Vaccines Worth the Effort?
Lessons from SARS may help prepare for bird flu
Incomplete vaccination could worsen the spread of avian flu
First Compilation of Tropical Ice Cores Shows Abrupt Global Climate Shift
Singapore facing unprecedented outbreak of Fusarium keratitis
East Asia may experience less drastic climate change
Scientists aim to thwart use of flu as bioweapon
Pakistani poultry industry demands 10-year tax holiday
Pandemic prevention plan approved for Asia Pacific
H5N1 threat puts human flu back in spotlight
Bird flu hits ninth poultry farm in Pakistan
Conjunctivitis caused by H7 avian influenza in a UK poultry worker
75 die of malaria in Assam, over 300,000 affected
Bird flu strain makes Britain slaughter chicken
China confirms new human case of bird flu
Chhattisgarh chicken samples test negative for flu
EU for support to bird flu-hit poultry market
Pakistan culls 40,000 chickens to control the outbreak of H5 strain
Pakistan suspects first human case of bird flu
Malaria alert in Tripura
RealOpt - Computer Program to Halt Pandemics
Pakistan confirms fourth bird flu outbreak
Madhya Pradesh relaxes ban on transporting poultry
Fresh bird flu scare in Pakistan
Malaria epidemic kills 50 in Assam
Thousand birds die in Orissa poultry farm
Pakistan confirms bird flu outbreak near Islamabad
Assam health alert after malaria claims 35
Bank notes, photocopiers could help check epidemics
WHO confirms Indonesia's 33rd bird flu victim
Bird flu small dark cloud on world economy: IMF
Unusual Outbreak of Streptococcus suis with Symptoms of Toxic Shock Syndrome in China
More donor money needed for bird flu: UN official
First case of H5N1 virus confirmed in Britain
Bird flu scare: Bangladesh burns Indian chicks
91 infants die in Indian hospital, probe ordered
Avian flu lab likely in Bharatpur Bird Sanctuary
U.S. Unlikely To Have Enough Vaccines To Stop Avian Flu Pandemic
Third bird flu case among humans confirmed in Egypt
Pakistan confirms presence of bird flu
Meningitis claims 34 lives in Delhi in three months
Attractive birds more immune against bird flu
Culling operations completed in Maharashtra
Rapid diagnostic test for viral hemorrhagic fevers developed
Minor mutations in avian flu virus increase chances of human infection
Egypt reports second suspected human case of bird flu
43 Percent of Swaziland Population is HIV Positive
Bhopal shrugs off flu scare
Egypt confirms first human death of bird flu

Chief Medical Editor: Dr Sanjukta Acharya; Managing Editor & Founder: Dr Himanshu Tyagi; Editors: Dr Rashmi Yadav, Dr Ankush Vidyarthi; Chief Correspondent: Dr Priya Saxena
© Copyright 2004 by rxpgnews.com
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