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Last Updated: Sep 8, 2007 - 1:21:03 PM |
Latest Research
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Cancer
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Nerve Tissue
Poliovirus Destroyed Neuroblastoma Tumors in Mice
The cause of one notorious childhood disease, poliovirus, could be used to treat the ongoing threat of another childhood disease, neuroblastoma. In the March 15 issue of Cancer Research, researchers from Stony Brook University report that an attenuated -- or non-virulent -- form of poliovirus is effective in obliterating neuroblastoma tumors in mice, even when the mice had been previously vaccinated against the virus.
Mar 23, 2007 - 3:05:52 AM
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Latest Research
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Cancer
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Nerve Tissue
Coblation SpineWand offers relief for patients with spinal tumors
A radiologist at the University of California, San Diego (UCSD) School of Medicine has developed a new procedure to treat fractured vertebrae caused by spinal tumors, a procedure that may decrease the risk of complications, which are experienced by 5 to 10% of patients with malignant tumors of the spine.
May 7, 2006 - 4:14:00 PM
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Latest Research
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Cancer
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Nerve Tissue
Promising neuroblastoma treatment with hu14.18 antibody and gamma-delta-T lymphocytes combination
A new strategy that turns small populations of immune system cells into armies that track down and kill neuroblastoma throughout the body could save the lives of many children each year, according to investigators at St. Jude Children's Research Hospital. Neuroblastoma is a cancer that arises in immature nerve cells and affects mostly infants and children. The disease often has already spread throughout the body by the time the disease is diagnosed. The St. Jude strategy represents the successful translation of concepts into a combination therapy that proved effective in laboratory models of neuroblastoma; and that now includes the production of the drugs made to the high standards required for human clinical trials, the researchers say. Translating this kind of research into the clinic is important because today only 40 percent of children with neuroblastoma can be cured; children who suffer relapses following treatment are virtually incurable. The St. Jude study suggests that the immune system can be manipulated to target cancer cells that have become resistant to traditional chemotherapy.
Dec 22, 2005 - 4:35:00 PM
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Latest Research
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Cancer
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Nerve Tissue
Genetic clues guide customized treatment for neuroblastoma
A new study reports that a loss of genes on chromosome 1 or chromosome 11 raises the risk of death from the children's cancer neuroblastoma, even when other indicators seem to point to a lower-risk form of the disease. This research finding will help guide physicians to the most appropriate treatment for the cancer, which strikes the peripheral nervous system. The approach used may also be applied to customizing care for other cancers.
Nov 25, 2005 - 6:36:00 AM
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Latest Research
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Cancer
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Nerve Tissue
Methionine Aminopeptidase-2 (MetAP2) - New Therapeutic Target in Neurofibromatosis 1
Researchers studying a mouse model of neurofibromatosis 1 (NF1), a genetic condition that causes childhood brain tumors, have found their second new drug target in a year, a protein called methionine aminopeptidase-2 (MetAP2). An established drug, fumagillin, is already known to suppress the activity of MetAP2. Researchers at Washington University School of Medicine in St. Louis showed that fumagillin significantly slowed the rapid proliferation of cultured mouse brain cells that resulted from the loss of Nf1, the gene that causes neurofibromatosis 1. Evaluation of the ability of this class of drugs to control brain tumor growth in small animal models is planned.
Nov 2, 2005 - 11:56:00 AM
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Latest Research
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Cancer
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Nerve Tissue
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Acoustic Neuroma
No substantial risk of acoustic neuroma with mobile phone use
Scientists from the institute of cancer research in University of Leeds have recently published results from the largest investigation to date into the relationship between mobile phone use and the risk of acoustic neuroma, a nervous system tumour that occurs close to where mobile phones are held to the head.
Sep 4, 2005 - 8:17:00 PM
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