||Last Updated: Nov 17th, 2006 - 22:35:04
Regular aerobics protects men from colon cancer
Regular, moderate-to-vigorous aerobic exercise significantly reduces a risk factor associated with the formation of colon polyps and colon cancer in men, according to a study led by researchers at Fred Hutchinson Cancer Research Center.
Sep 13, 2006, 20:04
Role for MicroRNAs in Oxygenation, Nourishing of Colon Tumors
Researchers from the University of Pennsylvania School of Veterinary Medicine have identified how molecules of microRNA are responsible for the growth of blood vessels in a model for human colon cancer. The process, called angiogenesis, results in ability of ravenous cancer cells to recruit blood vessels and receive a steady supply of nutrients and oxygen. The findings, which appear in the online version of Nature Genetics, suggest that these microRNAs might also be a good target for future therapeutics designed to slow the growth of cancer cells.
Aug 1, 2006, 14:46
New genetic test to spotlight heightened bowel cancer risk
Cancer Research UK scientists have devised a new means to identify groups of people genetically more at risk from bowel cancer. This could lead to new measures to prevent the disease for thousands of people in the future, according to a study published in the New England Journal of Medicine.
Jul 10, 2006, 20:18
$2.6 million in grants for metastatic colon cancer research
The American Association for Cancer Research announces the first 11 recipients of the new Jeannik M. Littlefield-AACR Grants in Metastatic Colon Cancer Research. The awards, ranging to $250,000, were established in February 2006, to support innovative research projects designed to accelerate the discovery and development of new agents to treat metastatic colon cancer
Jul 8, 2006, 21:59
NSAIDs don't reduce colorectal cancer risk in chronic smokers
It is widely known that the use of aspirin and other nonsteroidal anti-inflammatory drugs, or NSAIDS, may reduce the risk of colorectal cancer by up to 40 percent, but this protective effect may not extend to long-term smokers, who already face an increased risk of the disease, according to a study led by researchers at Fred Hutchinson Cancer Research Center.
Jul 1, 2006, 17:29
Timing of radiation treatments for colon cancer may need adjusting
Scientists have unexpectedly discovered that mice with the gene defect that causes colon cancer in humans can differ from normal mice in how they respond to radiation treatments. The large intestine carrying the gene defect in mice that received staggered doses of radiation was three to four times more resistant to the radiation than in control mice.
Apr 10, 2006, 16:16
How growth hormone therapy can lead to colon polyps
The use of growth hormone therapy has been linked in some people to the development of colon polyps, a possible precursor to colorectal cancer – but medical researchers have debated the extent of a cancer risk. In addition, the reason for a polyp link to growth hormone has been unclear. But new research from the University of North Carolina at Chapel Hill indicates the probable answer: loss of function of one of a pair of genes that normally would inhibit growth hormone signals inside the cell. The study also offers a possible molecular marker that could help determine which people taking growth hormone therapy are at increased risk for colon polyps. Researchers already know that colon polyps tend to occur in people who already have excessive amounts of growth hormone, such as those with a disease called acromegaly, or gigantism.
Apr 10, 2006, 16:10
Review study sets treatment standard for elderly with colon cancer
One of the newest and most potent chemotherapies for colon cancer is as safe and effective for the elderly as it is for younger patients, based on a University of North Carolina at Chapel Hill-led data review. The analysis focused on nearly 4,000 colon cancer patients who had been enrolled in four large-scale clinical trials that began in the 1990s nationwide and in Europe. The four studies helped establish the value against colorectal cancer of the chemotherapy regimen known as FOLFOX4, a combination of the standard anticancer drugs 5-fluorouracil (5-FU), leucovorin and the new drug oxaliplatin.
Feb 12, 2006, 18:53
Eating red meat could damage DNA by N-nitrosocompounds
Eating a lot of red meat could damage the body's DNA and raise the risk of bowel cancer, a study says.
Feb 3, 2006, 15:38
Diet pattern may effect the development of colon cancer
A recent study in The American Journal of Gastroenterology revealed that patterns in diet may effect the development of colorectal adenomas, or precancerous polyps of the colon.
Dec 19, 2005, 22:33
High dietary fiber intake do not reduce colorectal cancer risk
In an analysis combining data from 13 studies, high intake of dietary fiber was not associated with reduced risk of colorectal cancer, according to a study in the December 14 issue of JAMA.
Dec 14, 2005, 16:53
Chemotherapy after stage 3 colon cancer increases survival
More patients with stage III colon cancer are receiving chemotherapy after surgery, with an associated significant increase in 5-year survival, according to a study in the December 7 issue of JAMA. The study also found that women, blacks and the elderly were less likely to receive this treatment.
Dec 9, 2005, 18:48
Preventing bowel cancer in high risk families by screening with colonoscopy
BOWEL cancer rates could be reduced by up to 80 per cent in people with a moderate family history of the disease by screening with colonoscopy, according to new research published in the British Medical Journal.
Oct 25, 2005, 21:53
How TGFBR1*6A contributes to cancer development
A relatively common cancer susceptibility gene appears to be frequently acquired in metastatic lesions from colorectal cancer, and give cancer cells a growth advantage, according to a study in the October 5 issue of JAMA.
Oct 6, 2005, 21:36
Investigating the link between being overweight and colon cancer
Researchers at the University of Leeds are investigating the link between being overweight and the risk of colon cancer with a grant of £98,587 from the world cancer research fund.
Sep 4, 2005, 20:17
Aspirin Use Reduces Colorectal Cancer Risk Among Women
Women who took two or more aspirin or NSAIDs per week for more than 10 years significantly reduced their risk of colorectal cancer, according to an article in the August 24/31 issue of JAMA.
Aug 24, 2005, 19:22
Study Examines Racial Disparities in Colon Cancer Treatment
Elderly black and white colon cancer patients are equally likely to consult with medical oncologists, but they do not receive recommended adjuvant treatment at the same rates after this consultation, according to a new study.
Aug 19, 2005, 04:59
Panitumumab gets fast track designation for metastatic colorectal cancer
Amgen and Abgenix, Inc. today announced that the U.S. Food and Drug Administration (FDA) has granted fast track designation for panitumumab, an experimental fully human monoclonal antibody directed against the epidermal growth factor receptor (EGFr), for patients with metastatic colorectal cancer who have failed standard chemotherapy treatment.
Aug 1, 2005, 23:27
Updated Phase II COFU Trial Data
ADVENTRX Pharmaceuticals, Inc. (Amex:ANX) today announced response data from all 48 measurable patients in its 50-patient Phase II trial with CoFactor(TM) and 5-fluorouracil (5-FU) as a first-line treatment for metastatic colorectal cancer. CoFactor is ADVENTRX's biomodulator designed to enhance the effects of the widely used cancer drug, 5-FU.
Jun 20, 2005, 18:56
FDA Approves Capecitabine for Adjuvant Treatment of Colon Cancer
Roche announced today that the U.S. Food and Drug Administration (FDA) has approved Xeloda(R) (capecitabine) -- an innovative oral chemotherapy -- for the adjuvant (post-surgery) treatment of patients with Dukes' C colon cancer.
Jun 17, 2005, 09:43
FDA Approves Oral Chemotherapy Pill for Colon Cancer
THE FDA HAS APPROVED THE ORAL CHEMOTHERAPY, XELODA, TO TREAT DUKES’ C COLON CANCER PATIENTS WHO HAVE UNDERGONE COMPLETE RESECTION OF THE PRIMARY TUMOR WHEN FLUOROPYRIMIDINE THERAPY ALONE IS PREFERRED.
Jun 17, 2005, 09:22
Chemotherapy options improve for patients with advanced colorectal cancer
For the first time, researchers have shown that a chemotherapy regimen of capecitabine plus oxaliplatin (CAPOX) is as safe and effective as infusional 5-fluorouracil/folinic acid plus oxaliplatin (FUFOX) in the first-line treatment of metastatic colorectal carcinoma (MCRC). The findings are reported today at the 2nd ESMO Scientific & Educational Conference (ESEC) in Budapest, Hungary.
Jun 7, 2005, 11:59
Oncolytic Herpes simplex virus shows early promise against colorectal cancer
A single injection of a genetically engineered virus has shown promise as a treatment for patients with colorectal cancer that has spread to the liver, according to preliminary results reported today at the 2nd ESMO Scientific & Educational Conference (ESEC) in Budapest, Hungary.
Jun 7, 2005, 11:51
Increased Vitamin B consumption reduces risk of colorectal cancer
According to a study published in the American Gastroenterological Association (AGA) journal Gastroenterology, women with a high dietary intake of vitamin B6 over several years have a decreased risk of colorectal cancer (CRC). Women who consume moderate to large amounts of alcohol in addition to vitamin B6 have more than a 70 percent reduced risk of developing CRC.
Jun 4, 2005, 02:05
More Data Support Panitumumab's Role in Metastatic Colorectal Cancer
Amgen Inc. (NASDAQ:AMGN), the world's largest biotechnology company, and Abgenix, Inc. (NASDAQ:ABGX), a leading antibody development company, today announced updated results from an ongoing Phase 2 study of panitumumab, a fully human monoclonal antibody directed against the epidermal growth factor receptor (EGFr).
May 17, 2005, 19:13
Aspirin May Reduce Risk of Colon Cancer Recurrence
Researchers from the Cancer and Leukemia Group B (CALGB), a national clinical research group in the United States, found that regular aspirin use among colon cancer patients following surgery reduced the risk of recurrence and death by approximately 50% compared with non-users.
May 17, 2005, 01:54
Keyhole Surgery Set to become Gold Standard in Colon Cancer
Keyhole surgery for colon cancer is as effective as open surgery in the short term, concludes a randomised trial published in this week’s issue of The Lancet.
May 13, 2005, 21:48
Check Colon Tumors for Signs of Syndrome - Study
A new study suggests that, after surgery, all colon tumors should be tested to learn if the patient may have an inherited syndrome that carries an extremely high risk of cancer. It also suggests that this prescreening can be done using a relatively inexpensive microscopy test already used in hospital pathology laboratories.
May 7, 2005, 18:51
Vitamin B6 May Reduce Risk of Colorectal Tumors
Vitamin B6 intake may be associated with lower future risk of colorectal tumors in women, according to a new study.
May 4, 2005, 17:26
Phase III Trail to Study Benefits of Panitumumab in Chemotherapy Regimens for Metastatic Colorectal Cancer
Amgen Inc. (Nasdaq: AMGN - News) and Abgenix, Inc. (Nasdaq: ABGX - News) today announced the initiation of a Phase 3 clinical study to evaluate the potential benefits of adding panitumumab, an experimental fully human monoclonal antibody, administered every other week to bevacizumab (Avastin(TM), Genentech) and either oxaliplatin- (Eloxatin®, sanofi-aventis) or irinotecan-based (Camptosar®, Pfizer) chemotherapy for the first-line treatment of metastatic colorectal cancer.
Apr 27, 2005, 09:11