RxPG News Feed for RxPG News

Medical Research Health Special Topics World
 Asian Health
 Food & Nutrition
 Men's Health
 Mental Health
 Occupational Health
 Public Health
 Sleep Hygiene
 Women's Health
 Canada Healthcare
 China Healthcare
 India Healthcare
 New Zealand
 South Africa
 World Healthcare
   Latest Research
 Alternative Medicine
  Bone Cancer
  Breast Cancer
  Cervical Cancer
  Gastric Cancer
  Liver Cancer
  Nerve Tissue
  Ovarian Cancer
  Pancreatic Cancer
  Prostate Cancer
  Rectal Cancer
  Renal Cell Carcinoma
  Risk Factors
  Testicular Cancer
 Clinical Trials
 Infectious Diseases
 Sports Medicine
   Medical News
 Awards & Prizes
   Special Topics
 Odd Medical News

Last Updated: Oct 11, 2012 - 10:22:56 PM
Colon Channel

subscribe to Colon newsletter
Latest Research : Cancer : Colon

   EMAIL   |   PRINT
Capecitabine : An Innovative Oral Chemotherapy Provides an Effective, Convenient Alternative for Colon Cancer Patients

Apr 3, 2005 - 10:14:00 AM
“For the first time colon cancer patients will have access to a unique treatment option that provides an effective oral therapy which is well-tolerated and can be taken at home.”

[RxPG] Roche announced today that the European authorities have approved Xeloda ( capecitabine ), an innovative oral chemotherapy, to be used as an adjuvant treatment ( post-surgery ) for colon cancer.

Patients will now have the choice of an effective, convenient chemotherapy that prolongs cancer free life, with a less serious side effect profile compared to the current standard treatment of intravenous 5-Fluorouracil/ leucovorin ( i.v. 5-FU/LV ).

Adjuvant chemotherapy is the standard treatment approach for stage III colon cancer where chemotherapy is given in order to destroy any cancerous cells remaining in the body after the tumour has been surgically removed.

“The European approval for Xeloda's new indication, again confirms Roche's commitment to providing innovative solutions for patients, whilst providing medical resource cost savings for today's healthcare providers” said William M. Burns, CEO of Roche's Pharmaceutical Division. “For the first time colon cancer patients will have access to a unique treatment option that provides an effective oral therapy which is well-tolerated and can be taken at home.”

“As the European approval decision was based on the landmark X-ACT trial, which showed that Xeloda should replace standard intravenous chemotherapy 5FU/LV, physicians and patients can be fully confident that they are using a very effective, safe and convenient treatment that is now available.” said Professor Jim Cassidy, Cancer Research UK Professor of Oncology and Chair of Medical Oncology, Beatson Oncology Centre, at the University of Glasgow in Scotland.

The landmark X-ACT ( Xeloda in Adjuvant Colon Cancer Therapy ) trial which successfully met its primary endpoint, demonstrated that Xeloda is at least as effective compared to intravenous 5-FU/LV in terms of disease-free survival with a superior reduction in the risk of cancer recurrence ( relapse-free survival ).

In addition, on average, a patient only needed 8 hospital visits when treated with Xeloda compared to 30 visits if treated with i.v. 5-FU/LV. This results in significant cost savings, an important advantage for doctors, nurses and pharmacists in today's healthcare environment.

In 2004 approximately 88,000 patients in Europe who had advanced colorectal or breast cancer benefited from Xeloda. Based on the new indication approximately 55,000 colon cancer patients a year can now also be treated with this effective and convenient oral cancer treatment. Global sales in 2004 were 534 million Swiss francs and are expected to accelerate in 2005.

Publication: Reddy, G. Efficacy of adjuvant capecitabine compared with bolus 5-Fluorouracil/Leucovorin regimen in Dukes C colon cancer: results from the X-ACT trial. Clin Colorectal Cancer, July 2004: 87-88. 2.2. McKendrick, J.J, Cassidy, J, et al. Capecitabine ( x ) is resource saving compared with i.v. bolus 5-FU/LV in adjuvant chemotherapy for Dukes' C colon cancer patients: Medical resource utilization ( MRU ) data from large phase III trial ( X-ACT ). Journ of Clin Oncol, 2004 ASCO Annual Meeting Proceedings ( Post Meeting Edition ). Vol 22, No 14S ( July supplement ), 2004: 3578
On the web: Roche 

Advertise in this space for $10 per month. Contact us today.

Related Colon News
Screening for colon cancer depends on location, race and ethnicity
Alcohol, cigarettes can cause bowel cancer
TSPAN1 expression-a useful tool to evaluate prognosis in colorectal cancer
Advances in screening and markers improve early detection of colorectal cancer
Rice bran can reduce the risk of intestinal cancer
Simutaneous removal of primary and liver metastasis favourable in some colorectal cancer patients
Follow-up endoscopic surveillance in colorectal cancer patients improves survival
Researchers identify cell pathway which plays a critical role in the development of colon cancer
Regular aerobics protects men from colon cancer
Role for MicroRNAs in Oxygenation, Nourishing of Colon Tumors

Subscribe to Colon Newsletter

Enter your email address:

 Additional information about the news article
Headquartered in Basel, Switzerland, Roche is one of the world's leading research-focused healthcare groups in the fields of pharmaceuticals and diagnostics. As a supplier of innovative products and services for the early detection, prevention, diagnosis and treatment of disease, the Group contributes on a broad range of fronts to improving people's health and quality of life. Roche is a world leader in diagnostics, the leading supplier of medicines for cancer and transplantation and a market leader in virology. In 2004 sales by the Pharmaceuticals Division totalled 21.7 billion Swiss francs, while the Diagnostics Division posted sales of 7.8 billion Swiss francs. Roche employs roughly 65,000 people in 150 countries and has R&D agreements and strategic alliances with numerous partners, including majority ownership interests in Genentech and Chugai.

All trademarks used or mentioned in this release are legally protected.
For any corrections of factual information, to contact the editors or to send any medical news or health news press releases, use feedback form

Top of Page

Contact us

RxPG Online



    Full Text RSS

© All rights reserved by RxPG Medical Solutions Private Limited (India)