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Latest Research : Ophthalmology : Retina
  Last Updated: Nov 2, 2013 - 11:52:55 AM

Latest Research : Ophthalmology : Retina : ARMD
Deficiency of the Dicer enzyme in retinal cells linked to age-related macular degeneration
A team of researchers, led by University of Kentucky ophthalmologist Dr. Jayakrishna Ambati, has discovered a molecular mechanism implicated in geographic atrophy, the major cause of untreatable blindness in the industrialized world.

Feb 6, 2011 - 4:45:23 PM

Latest Research : Ophthalmology : Retina : ARMD
Quit smoking to save your eyes
A UCLA study finds that even after age 80, smoking continues to increase one's risk for age-related macular degeneration (AMD), the leading cause of blindness in Americans over 65.
Jan 1, 2010 - 11:09:08 AM

Latest Research : Ophthalmology : Retina : ARMD
Post Menopausal Hormones - reduces risk of macular degeneration
Women who take postmenopausal hormones appear to have a lower risk of developing advanced stages of the eye disease age-related macular degeneration, especially if they had also taken oral contraceptives in the past, according to a report in the April issue of Archives of Ophthalmology, one of the JAMA/Archives journals.
Apr 14, 2008 - 1:52:27 PM

Latest Research : Ophthalmology : Retina
New Findings Indicate That Eyes Can Regenerate Damaged Retinas
Washington, March 20 - It might be possible to turn on the eye's own resources to regenerate damaged retinas, without the need for transplanting outside retinal tissue or stem cells, according to a new study.

Mar 20, 2008 - 11:32:50 AM

Latest Research : Ophthalmology : Retina : ARMD
Higher fish consumption have a reduced risk of advanced age-related macular degeneration
Individuals who have higher dietary intake of foods with omega-3 fatty acids and higher fish consumption have a reduced risk of advanced age-related macular degeneration, while those with higher serum levels of vitamin D may have a reduced risk of the early stages of the disease, according to two reports in the May issue of Archives of Ophthalmology, one of the JAMA/Archives journals.
May 14, 2007 - 8:33:58 PM

Latest Research : Ophthalmology : Retina
Genetics key factor in retinopathy of prematurity (ROP)
Genetics play a major role in predisposing infants to retinopathy of prematurity (ROP), a disease prevalent in premature infants that disrupts normal blood vessel development of the retina and can lead to blindness, researchers at Yale School of Medicine report in the November issue of Pediatrics.
Nov 24, 2006 - 9:24:18 AM

Latest Research : Ophthalmology : Retina : ARMD
HTRA1 gene linked to aggressive 'wet' age-related macular degeneration
A gene variant that increases the risk of developing the aggressive "wet" form of age-related macular degeneration (AMD), the most common cause of blindness in people over age 50, is reported in two recent articles in Science by researchers at Yale School of Medicine.
Nov 23, 2006 - 9:13:40 PM

Latest Research : Ophthalmology : Retina
Master Proteins Dictate Retinal Differentiation Timetable
The embryonic construction of the vertebrate retina is a highly ordered affair. Following a precise timetable, six different specialized cell types emerge from a mass of identical, proliferating cells. The process of retinal cell differentiation, when so-called progenitor cells stop dividing and choose among the six fates, depends primarily on homeobox genes, major regulators of embryonic patterning. How these genes control the timing of retinal cell differentiation has remained an open question—until now.
Aug 16, 2006 - 8:41:00 AM

Latest Research : Ophthalmology : Retina : ARMD
Yellow plant pigments lutein and zeaxanthin reduce risk of age-related macular degeneration
Women younger than age 75 years who eat diets rich in the yellow plant pigments lutein and zeaxanthin may have a reduced risk of developing the eye disease age-related macular degeneration, according to a report in the August issue of Archives of Ophthalmology, one of the JAMA/Archives journals. Age-related macular degeneration (AMD) occurs when the macula, the area at the back of the retina that produces the sharpest vision, deteriorates over time. The condition is the leading cause of blindness in aging Americans, according to background information in the article. There is no cure for AMD and limited treatment options are available to slow its progression, so research on preventive measures is essential. Previous studies have suggested a potential link between AMD and lutein and zeaxanthin, plant pigments known as carotenoids and found in leafy green vegetables, corn, egg yolks, squash, broccoli and peas. These compounds may reduce the risk of AMD by absorbing blue light that could damage the macula, by preventing free radicals from damaging eye cells and by strengthening eye cell membranes.
Aug 15, 2006 - 11:41:00 AM

Latest Research : Ophthalmology : Retina
Objective way to diagnose diseases of colour perception
Pictures of brain waves that reveal our ability to see colour could provide a new objective way to diagnose and monitor diseases that affect human colour perception. The research finding by a Universiy of New South Wales PhD student, Ms Mei Ying Boon, has earned her a nomination in this year's Fresh Science Awards.
Aug 10, 2006 - 2:59:00 PM

Latest Research : Ophthalmology : Retina
Antioxidants may slow retinal degeneration
Scientists at Johns Hopkins have successfully blocked the advance of retinal degeneration in mice with a form of retinitis pigmentosa (RP) by treating them with vitamin E, alpha-lipoic acid and other antioxidant chemicals.
Jul 20, 2006 - 8:22:00 PM

Latest Research : Ophthalmology : Retina : ARMD
Hormone Therapy Does Not Affect Age-Related Vision Loss
Postmenopausal hormone therapy does not appear to increase or decrease the overall risk of AMD among women, although combination hormones may slightly reduce the chances of developing certain risk factors or types of the condition, according to a report in the July issue of the Archives of Ophthalmology, one of the JAMA/Archives journals.
Jul 12, 2006 - 5:59:00 AM

Latest Research : Ophthalmology : Retina : ARMD
Eating Fish Protects Against Macular Degeneration
In a study, Brian Chua, B.Sc., M.B.B.S., M.P.H., Westmead Millennium Institute and Vision Co-operative Research Centre, Syndney, Australia, and colleagues examined the association between dietary fat intake and AMD risk in 2,895 Australians age 49 years or older, beginning in 1992-1994. At the beginning of the study and again five years later, participants had a comprehensive eye exam that included photographs of the retina. They also filled out a questionnaire with data about food types and portion sizes consumed, including specific information about margarines, butters, oils and supplements.
Jul 12, 2006 - 5:53:00 AM

Latest Research : Ophthalmology : Retina : ARMD
Research Highlights Risk Factors For Age-Related Vision Loss
Eating fish frequently may be associated with decreased chances of developing age-related macular degeneration, while smoking nearly doubles the risk for this common cause of vision loss and hormone therapy appears to have no effect, according to three articles in the July issue of the Archives of Ophthalmology, one of the JAMA/Archives journals.
Jul 12, 2006 - 5:50:00 AM

Latest Research : Ophthalmology : Retina : ARMD
FDA approves ranibizumab for the treatment of wet age-related macular degeneration
The Food and Drug Administration (FDA) today approved Lucentis (ranibizumab injection) for the treatment of patients with neovascular (wet) age-related macular degeneration (AMD). Lucentis is the first treatment which, when dosed monthly, can maintain the vision of more than 90 percent of patients with this type of AMD.
Jul 6, 2006 - 2:23:00 AM

Latest Research : Ophthalmology : Retina : ARMD
High Body Mass Index Increase the Genetic Risk of AMD
Current cigarette smoking was associated with a fivefold increased risk and high BMI (30 or higher) was associated with a twofold higher risk of AMD. The homozygous risk genotype (CC) plus smoking conferred a tenfold higher risk of AMD, compared with non-smokers with the non-risk (TT) genotype, while the risk genotype plus higher BMI increased risk of AMD almost sixfold. Gene plus environment risk scores provided an area under the receiver operating characteristic (ROC) curve of 0.70-0.75. The attributable risks for the combination of genes and environment were 69% to 73%.
Jul 1, 2006 - 5:41:00 PM

Latest Research : Ophthalmology : Retina : ARMD
Ranibizumab Approved for Wet Age-Related Macular Degeneration
The Food and Drug Administration (FDA) approved Lucentis (ranibizumab injection) for the treatment of patients with neovascular (wet) age-related macular degeneration (AMD). Lucentis is the first treatment which, when dosed monthly, can maintain the vision of more than 90 percent of patients with this type of AMD. Lucentis is a new molecular entity (NME), meaning it contains an active substance that has never before been approved for marketing in any form in the United States. Lucentis will be the first FDA--approved product to provide prescription information in the new format for prescription drug package inserts, to provide professionals and consumers clear and concise prescription information.
Jul 1, 2006 - 4:41:00 PM

Latest Research : Ophthalmology : Retina
First look at the 'birth' of a retina cell
Scientists at the University of Michigan Kellogg Eye Center have gained new insight into the way an embryonic retina cell develops and then commits itself to a specific role. They have observed a small window of opportunity during which a cell has been designated to play a particular role, but has not yet begun to function as such.
May 7, 2006 - 3:25:00 PM

Latest Research : Ophthalmology : Retina : ARMD
New genetic discovery explains 74 percent cases of age-related macular degeneration
A new study, led by researchers at Columbia University Medical Center, pinpoints the role that two genes – Factor H and Factor B – play in the development of nearly three out of four cases of age-related macular degeneration (AMD), a devastating eye disease that affects more than 10 million people in the United States. Findings indicate that 74 percent of AMD patients carry certain variants in one or both genes that significantly increase their risk of this disease.
Mar 6, 2006 - 5:31:00 PM

Latest Research : Ophthalmology : Retina : ARMD
Just two genes, Factor H and Factor B, cause blindness in millions
Just two genes cause blindness in millions of older people across the globe, a discovery that scientists say could aid the development of new treatments for the condition.
Mar 6, 2006 - 4:56:00 PM

Latest Research : Ophthalmology : Retina
Marijuana for Diabetic retinopathy ?
Scientists have discovered a compound in marijuana that could protect against eye damage in diabetics.
Feb 28, 2006 - 9:26:00 PM

Latest Research : Ophthalmology : Retina
Controlling SPARC levels key to controlling angiogenesis in macular degeneration
For the second time in a week Dr. Jayakrishna Ambati, UK HealthCare physician and associate professor and vice chair of the Department of Ophthalmology and Visual Sciences, announced a discovery from his lab that will affect the future of macular degeneration treatment and research.
Feb 3, 2006 - 4:08:00 PM

Latest Research : Ophthalmology : Retina
Making new blood vessels: keeping the lines of sight open
The creation of new blood vessels, known as angiogenesis, is a process used to supply oxygen and nutrients at sites of tissue injury. Angiogenesis is known to be stimulated during hypoxia (low oxygen conditions, when new vessels are needed). However, the mechanisms by which hypoxia leads to new vessel formation is poorly understood.
Jan 20, 2006 - 1:56:00 PM

Latest Research : Ophthalmology : Retina : ARMD
Antioxidants reduce risk of age-related macular degeneration
A diet with a high intake of beta carotene, vitamins C and E, and zinc is associated with a substantially reduced risk of age-related macular degeneration in elderly persons, according to a study in the December 28 issue of JAMA. Age-related macular degeneration (AMD) is a degenerative disorder of the macula, the central part of the retina, and is the most common cause of irreversible blindness in developed countries, according to background information in the article. Late-stage AMD results in an inability to read, recognize faces, drive, or move freely. The prevalence of late AMD steeply increases with age, affecting 11.5 percent of white persons older than 80 years. In the absence of effective treatment for AMD, the number of patients severely disabled by late-stage AMD is expected to increase in the next 20 years by more than 50 percent to 3 million in the United States alone. Epidemiological studies evaluating both dietary intake and serum levels of antioxidant vitamins and AMD have provided conflicting results. One study (called AREDS) showed that supplements containing 5 to 13 times the recommended daily allowance of beta carotene, vitamins C and E, and zinc given to participants with early or single eye late AMD resulted in a 25 percent reduction in the 5-year progression to late AMD.
Dec 28, 2005 - 6:23:00 PM

Latest Research : Ophthalmology : Retina
Successful tests of new treatments for Leber congenital amaurosis (LCA)
A team led by Krzysztof Palczewski, Ph.D., chair of pharmacology at the Case Western Reserve University School of Medicine, has taken the first steps in treating an eye disease causing irreversible congenital blindness in millions of people worldwide by successfully testing two new treatments in mice.
Nov 2, 2005 - 11:21:00 AM

Latest Research : Ophthalmology : Retina
First-ever Images of Living Human Retinas Sprung a Surprise
First-ever images of living human retinas have yielded a surprise about how we perceive our world. Researchers at the University of Rochester have found that the number of color-sensitive cones in the human retina differs dramatically among people—by up to 40 times—yet people appear to perceive colors the same way. The findings, on the cover of this week's journal Neuroscience, strongly suggest that our perception of color is controlled much more by our brains than by our eyes.
Oct 27, 2005 - 12:32:00 AM

Latest Research : Ophthalmology : Retina : ARMD
VISION - VEGF Inhibition Study in Ocular Neovascularization Exploratory Analysis
Age-related macular degeneration (AMD) is the leading cause of blindness in older patients in the developed world. Vascular endothelial growth factor is one of the key mediators stimulating the abnormal blood vessel growth and leakage characteristic of the exudative (wet) form of the condition. Pegaptanib sodium (Macugen) is a new treatment for exudative AMD, and has been shown to stabilize vision in approximately 70 percent of cases.
Oct 8, 2005 - 5:57:00 AM

Latest Research : Ophthalmology : Retina : ARMD
Potential role of amyloid-beta in the pathogenesis of age-related macular degeneration
Age-related macular degeneration (AMD) is the main cause of blindness in patients over the age of 60. In these AMD patients, choroidal neovascularization (CNV) is the most common cause of visual loss.
Sep 27, 2005 - 1:21:00 AM

Latest Research : Ophthalmology : Retina : ARMD
FDA Approval to be filed for Ranibizumab as Treatment of Wet ARMD
Genentech, Inc. (NYSE: DNA) announced today plans to file a complete Biologics License Application (BLA) for the investigational drug Lucentis™ (ranibizumab) in December 2005. In addition, the company announced that it is in discussion with the U.S. Food and Drug Administration (FDA) regarding plans to initiate a Phase IIIb clinical study of Lucentis for patients with wet age-related macular degeneration (AMD). The study is anticipated to begin before the end of 2005. One-year Phase III data from the MARINA study presented at the annual meeting of the American Society of Retina Specialists in July showed Lucentis improved vision in patients with wet AMD.
Sep 9, 2005 - 5:25:00 PM

Latest Research : Ophthalmology : Retina : ARMD
Smoking and Age Related Macular Degeneration (AMD)
Smoking greatly increases your chance of developing age-related macular degeneration (AMD), which leads to severe and irreversible sight-loss, according to an article published in the Royal College of Ophthalmologist's journal Eye this week (published online 7th September 2005).
Sep 7, 2005 - 6:06:00 PM

Latest Research : Ophthalmology : Retina : ARMD
Cogan Award to macular degeneration scientist
The Association for Research in Vision and Ophthalmology (ARVO) announced today that Joshua L. Dunaief, MD, PhD, has been selected to receive the 2006 Cogan Award during ARVO's Annual Meeting to be held in Fort Lauderdale, Fla., in May 2006.
Sep 1, 2005 - 1:23:00 AM

Latest Research : Ophthalmology : Retina : ARMD
Age-related maculopathy (ARM) gene discovered
University of Pittsburgh researchers have discovered a gene linked to age-related maculopathy (ARM), the leading cause of untreatable blindness in the elderly. Their discovery suggests a simple test might be able to identify those at risk for what is commonly known as macular degeneration (AMD) and may lead to the development of more effective preventive strategies.
Aug 17, 2005 - 1:54:00 AM

Latest Research : Ophthalmology : Retina : ARMD
Role of melanin in preventing macular degeneration
Two studies from an unusual research partnership at the University of Chicago appear to have resolved a long-standing dispute about the role of melanin in the eye. The studies, one published in the Proceedings of the National Academy of Sciences (PNAS) and one early online in the Journal of the American Chemical Society (JACS), also suggest a new way to prevent a common cause of blindness.
Jul 30, 2005 - 1:49:00 AM

Latest Research : Ophthalmology : Retina : ARMD
Chromosome region for macular degeneration pinpointed
Age-related macular degeneration is the leading cause of blindness in older adults, yet researchers are still in the dark about many of the factors that cause this incurable disease.
Jul 27, 2005 - 1:43:00 AM

Latest Research : Ophthalmology : Retina : ARMD
Eye Saver Easy Reading Light Bulb useful in macular degeneration
For years, there has been much research and development to improve poor eyesight, including the use of scratch-resistant and radiation-blocking lenses. Now, a revolutionary product for eye correction focuses specifically on the needs of those in working environments, called the Eye Saver Easy Reading Light Bulb.
Jul 27, 2005 - 1:39:00 AM

Latest Research : Ophthalmology : Retina : ARMD
FDA Approves Anecortave Acetate Suspension for Age-Related Macular Degeneration
Alcon, Inc. (NYSE:ACL) announced today that the U.S. Food and Drug Administration (FDA) has issued an approvable letter for its New Drug Application (NDA) for RETAANE(R) 15 mg (anecortave acetate suspension). RETAANE(R) suspension is an investigational treatment for preserving the vision of patients with wet age-related macular degeneration (AMD).
May 25, 2005 - 11:05:00 AM

Latest Research : Ophthalmology : Retina : ARMD
Variation in immune response gene causes age-related macular degeneration
Age-related macular degeneration, the leading cause of blindness in the elderly, occurs when a common inherited gene variation is triggered, possibly by an infection, according to a new study led by researchers at Columbia University Medical Center and the University of Iowa, with an international research team.
Apr 30, 2005 - 1:26:00 AM

Latest Research : Ophthalmology : Retina : ARMD
Common painkillers may play a role in preventing or slowing the progression of macular degeneration
Rheumatoid arthritis patients treated with anti-inflammatory drugs are 10 times less likely to develop age-related macular degeneration (AMD), the most common form of blindness in people over 55, researchers at the University of British Columbia and University of Saskatchewan have found.
Apr 27, 2005 - 1:34:00 AM

Latest Research : Ophthalmology : Retina : ARMD
Smoking doubles risk of age related macular degeneration
The risk of macular degeneration increases with age and is the most common cause of blindness in the UK, affecting around 200,000 elderly people.
Apr 13, 2005 - 1:37:00 AM

Latest Research : Ophthalmology : Retina : ARMD
New Collaboration to discover genes responsible for Macular Degeneration
AMD is the leading cause of irreversible vision loss in the developed world, affecting 15 to 20 percent of individuals over the age of 60, or an estimated 50 million individuals.
Apr 1, 2005 - 5:01:00 PM

Latest Research : Ophthalmology : Retina : ARMD
Gene variation could be responsible for age-related macular degeneration
Half of all cases of age-related macular degeneration, the leading cause of blindness among the elderly, could be caused by a variation in a particular gene, according to UT Southwestern Medical Center researchers involved in a multicenter study.
Mar 27, 2005 - 2:22:00 AM

Latest Research : Ophthalmology : Retina : ARMD
Genetics important in age-related macular degeneration
Genes play a substantial role in the development of age-related macular degeneration (AMD), one of the leading causes of irreversible blindness among older individuals, according to an article in the March issue of Archives of Ophthalmology, one of the JAMA/Archives journals.
Mar 15, 2005 - 1:57:00 AM

Latest Research : Ophthalmology : Retina : ARMD
Gene Variation implicated for Age-Related Macular Degeneration (ARMD)
Half of all cases of age-related macular degeneration, the leading cause of blindness among the elderly, could be caused by a variation in a particular gene, according to UT Southwestern Medical Center researchers involved in a multicenter study.
Mar 11, 2005 - 4:28:00 PM

Latest Research : Ophthalmology : Retina : ARMD
Gene variant increases risk of age-related macular degeneration
Researchers at Duke University Medical Center and Vanderbilt University Medical Center have pinpointed the first major gene that determines an individual's risk for developing age-related macular degeneration (AMD). The chronic, progressive disease -- which affects as many as 15 million people in the United States -- is the leading cause of visual impairment and legal blindness in the elderly.
Mar 11, 2005 - 2:04:00 AM

Latest Research : Ophthalmology : Retina : ARMD
Major role of genes in age-related blindness disease
By combining the tools of high-throughput biology and statistical genetics, scientists at Rockefeller University, Yale University School of Public Health and the National Eye Institute have identified a gene that confers susceptibility to age-related macular degeneration (AMD), the most common cause of vision loss in the United Sates for those over 60. Reported in the March 10 issue of Science Express, the finding opens the door for new investigations of the role of genes in developing AMD and possible treatments for this disease.
Mar 11, 2005 - 2:00:00 AM

Latest Research : Ophthalmology : Retina : ARMD
Gene for age-related macular degeneration discovered
Researchers at Yale School of Medicine have identified a gene for age-related macular degeneration (AMD) on a region of chromosome 1, leading the way for targeted treatment for this widespread eye disease that causes blindness in millions of people.
Mar 10, 2005 - 2:26:00 AM

Latest Research : Ophthalmology : Retina : ARMD
A 'Mouse Model' to Test Potential Therapies for Age-Related Macular Degeneration
Researchers at the University of California, San Diego (UCSD) School of Medicine and the University of Utah have developed a mouse model of Age-Related Macular Degeneration (AMD), the leading cause of blindness in people over age 55, and Stargardt Macular Degeneration (STGD), a form of the disease that affects children and young adults.
Mar 7, 2005 - 8:01:00 AM

Latest Research : Ophthalmology : Retina : ARMD
Self-management training benefits macular degeneration patients
A 12-hour self-management program for individuals with advanced age-related macular degeneration (AMD) leads to lasting improvements in mood and function, especially in depressed patients, and decreases the development of clinical depression in AMD patients over time, according to a University of California, San Diego (UCSD) Shiley Eye Center study published in the January 2005 Archives of Ophthalmology.
Jan 12, 2005 - 2:15:00 AM

Latest Research : Ophthalmology : Retina : ARMD
Pegaptanib provides benefit for neovascular age-related macular degeneration
Results from two concurrent, prospective, double-blind, multi-center clinical trials show that pegaptanib (Macugen), an anti-vascular endothelial growth factor therapy, is an effective treatment for neovascular age-related macular degeneration (AMD), according to a paper in the Dec. 30 issue of the New England Journal of Medicine. Macugen was approved by the Food and Drug Administration on Dec. 17.
Dec 30, 2004 - 2:19:00 AM

Latest Research : Ophthalmology : Retina : ARMD
Growing epidemic of wet AMD
Retina specialists and ophthalmologists are encouraged by promising new scientific approaches that could have the potential to reduce the devastating effects of wet AMD for patients and offer the medical community a new paradigm of care, according to presentations made at the 2004 Annual Meeting of the American Academy of Ophthalmology in New Orleans.
Oct 27, 2004 - 2:40:00 AM

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