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Last Updated: May 10, 2008 - 3:38:29 AM |
Latest Research
Suspected cause of type 1 diabetes caught 'red-handed' for the first time
May 8, 2008 -- Scientists at Washington University School of Medicine in St. Louis working with diabetic mice have examined in unprecedented detail the immune cells long thought to be responsible for type 1 diabetes.
May 9, 2008 - 4:00:00 AM
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Latest Research
Harmful blood glucose levels linked to defective gene
A genetic mutation that can raise the amount of glucose in a person's
blood to harmful levels is identified today in a study in the journal
Science.
May 1, 2008 - 4:00:00 AM
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Latest Research
Researchers uncover new genetic links to psoriasis
In the first comprehensive study of the genetic basis of psoriasis, researchers at Washington University School of Medicine in St. Louis have discovered seven new sites of common DNA variation that increase the risk of the troublesome skin condition. They also found that variations in one genetic region link psoriasis and a related joint disorder, psoriatic arthritis, to four autoimmune diseases: type 1 diabetes, Grave's disease, celiac disease and rheumatoid arthritis.
Apr 3, 2008 - 4:00:00 AM
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Latest Research
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Endocrinology
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Diabetes
How diabetes accelerates atherosclerosis
Researchers have discovered how diabetes, by driving inflammation and slowing blood flow, dramatically accelerates atherosclerosis, according to research to be published in the March 14 edition of the journal Circulation Research.
Mar 13, 2008 - 10:12:00 AM
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Latest Research
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Endocrinology
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Diabetes
CRTC2 inhibitors may be needed for maintaining sugar levels
Continually revved up insulin production, the kind that results from overeating and obesity, slowly dulls the body’s response to insulin. As a result, blood sugar levels start to creep up, setting the stage for diabetes-associated complications such as blindness, stroke and renal failure. To make matters even worse, chronically elevated blood sugar concentrations exacerbate insulin resistance.
Mar 9, 2008 - 6:57:23 AM
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Latest Research
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Endocrinology
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Diabetes
A focus on the ADVANCE and RISC studies in the Diabetes UK conference March 2008
In the recent Annual Professional Conference held in Glasgow(March 5-7, 2008) an interesting talk was on the late breaking trials. There was a focus on the ADVANCE trial (presented by Dr Neil Poulter, London) and the RISC trial (presented by Dr Mark Walker, Newcastle). Here is a brief overview of the studies and the thoughts of the speakers and audience.
Mar 8, 2008 - 7:22:07 AM
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Latest Research
Type 2 diabetes may be caused by intestinal dysfunction
NEW YORK (March 5, 2008) -- Growing evidence shows that surgery may effectively cure Type 2 diabetes -- an approach that not only may change the way the disease is treated, but that introduces a new way of thinking about diabetes.
Mar 5, 2008 - 5:00:00 AM
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Latest Research
Protein target for diabetes drug regulates blood pressure
University of Iowa researchers have identified a molecular pathway in blood vessels that controls blood pressure and vascular function and may help explain why certain drugs for type II diabetes also appear to lower patients' blood pressure. The study is published in the March 5 issue of Cell Metabolism.
Mar 4, 2008 - 5:00:00 AM
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Latest Research
Study: highly involved patients don't always see better health outcomes
Patients who prefer to be highly involved in their treatment don't necessarily have better luck managing chronic health conditions, a new study suggests.
Feb 22, 2008 - 5:00:00 AM
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Latest Research
Intensive blood sugar treatment in trial of diabetes and cardiovascular disease changed
The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health has stopped one treatment within a large, ongoing North American clinical trial of diabetes and cardiovascular disease 18 months early due to safety concerns after review of available data, although the study will continue.
Feb 6, 2008 - 11:40:00 PM
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Latest Research
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Endocrinology
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Diabetes
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Insulin Resistance
Insulin inhibits resistin expression and secretion
Does resistin play a role in insulin resistance? Is insulin the major regulator of resistin? A research article to be published on January 7, 2008 in the World Journal of Gastroenterology (volume 14, issue 1) addresses these questions.
Jan 16, 2008 - 2:07:29 PM
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Latest Research
Oral anti diabetic substance discovered
Research in the Department of Biology at the Faculty of Science and Science Education of the University of Haifa has discovered a substance that may become an oral treatment for diabetes and its complications. The substance, which is derived from yeast, is called Glucose Tolerance Factor (GTF). The research is now at the stage where the substance has been successfully tested on diabetic rats and was found to reduce sugar and lipids in the blood of the treated animals. The next stage of the research is to evaluate GTF efficacy in humans, said Dr. Nitsa Mirsky, who is conducting the research.
Dec 24, 2007 - 5:00:00 AM
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Latest Research
Stanford researchers shed light on black box of gestational diabetes
STANFORD, Calif. - A protein in the pancreas is giving researchers at the Stanford University School of Medicine their first chance at cracking the code that determines how diabetes develops during pregnancy, a finding that could lead to new treatments for all forms of diabetes.
Nov 1, 2007 - 4:00:00 AM
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Latest Research
'Knocking out' cell receptor may help block fat deposits in tissues, prevent weight gain
CINCINNATI—University of Cincinnati (UC) pathologists have identified a new molecular target that one day may help scientists develop drugs to reduce fat transport to adipocytes (fat cells) in the body and prevent obesity and related disorders, like diabetes.
Oct 25, 2007 - 4:00:00 AM
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Latest Research
'Twinkle after effect' can help retinal patients detect vision loss quickly and cheaply
Boston, MA—Scientists at Schepens Eye Research Institute have discovered a simple and inexpensive way for patients with retinal and other eye disease to keep track of changes in their vision loss. In a study published in this week’s PLoS One (October 24, 2007) they demonstrate that a compelling visual illusion known as the induced twinkle after-effect (TAE) can accurately identify the location and breadth of actual blind spots in people with retinal disease. The twinkle after-effect is a “twinkling” that people can see in a blind spot when they stare at a blank screen after staring at a noisy visual target such as a detuned television screen.
Oct 23, 2007 - 4:00:00 AM
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Latest Research
Exercise improves thinking, reduces diabetes risk in overweight children
Just three months of daily, vigorous physical activity in overweight children improves their thinking and reduces their diabetes risk, researchers say.
Oct 22, 2007 - 4:00:00 AM
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Latest Research
Cross-species transplant in rhesus macaques is step toward diabetes cure for humans
St. Louis, Oct. 18, 2007 — With an eye on curing diabetes, scientists at Washington University School of Medicine in St. Louis have successfully transplanted embryonic pig pancreatic cells destined to produce insulin into diabetic macaque monkeys – all without the need for risky immune suppression drugs that prevent rejection.
Oct 18, 2007 - 4:00:00 AM
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Latest Research
Low doses of a red wine ingredient fight diabetes in mice
Even relatively low doses of resveratrol—a chemical found in the skins of red grapes and in red wine—can improve the sensitivity of mice to the hormone insulin, according to a report in the October issue of Cell Metabolism, a Cell Press publication. As insulin resistance is often characterized as the most critical factor contributing to the development of type 2 diabetes, the findings “provide a potential new therapeutic approach for preventing or treating” both conditions, the researchers said.
Oct 2, 2007 - 4:00:00 AM
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Latest Research
Genetic 'roadblock' hoped to inspire future type 2 diabetes research
Toronto, ON (October 2, 2007) – A team of Mount Sinai Hospital researchers has found that a “genetic roadblock” identified in a recent study could pave the way toward novel treatments for type 2 diabetes.
Oct 2, 2007 - 4:00:00 AM
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Latest Research
Botched production of insulin molecule may lead to diabetes
ANN ARBOR, Mich. — Picture a pretzel factory production line, with conveyer belts carrying the dough, formed into unbaked pretzels, down to the oven to be cooked.
Oct 1, 2007 - 4:00:00 AM
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Latest Research
Joslin researchers uncover potential role of leptin in diabetes
BOSTON–October 1, 2007–A new Joslin-led study has shown that leptin, a hormone known mainly for regulating appetite control and energy metabolism, plays a major role in islet cell growth and insulin secretion. This finding opens up new avenues for studying leptin and its role in islet cell biology, which may lead to new treatments for diabetes. This study appears in the October 2007 issue of The Journal of Clinical Investigation.
Oct 1, 2007 - 4:00:00 AM
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Latest Research
'Bad carbs' not the enemy, University of Virginia professor finds
The latest common wisdom on carbohydrates claims that eating so-called “bad” carbohydrates will make you fat, but University of Virginia professor Glenn Gaesser says, “that’s just nonsense.” Eating sandwiches with white bread, or an occasional doughnut, isn't going to kill you, or necessarily even lead to obesity, he said.
Sep 28, 2007 - 4:00:00 AM
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Latest Research
Discovery supports theory of Alzheimer's disease as form of diabetes
EVANSTON, Ill. --- Insulin, it turns out, may be as important for the mind as it is for the body. Research in the last few years has raised the possibility that Alzheimer’s memory loss could be due to a novel third form of diabetes.
Sep 26, 2007 - 4:00:00 AM
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Latest Research
Consumption of omega-3 fatty acids associated with decreased risk of type 1 diabetes
Preliminary research suggests that in children at increased risk for type 1 diabetes, dietary intake of omega-3 fatty acids was associated with a reduced risk of pancreatic islet autoimmunity, which is linked to the development of diabetes, according to an article in the Sept. 26 issue of JAMA.
Sep 25, 2007 - 4:00:00 AM
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Latest Research
Breath analysis offers potential for noninvasive blood sugar monitoring in diabetes
Irvine, Calif. — Breath-analysis testing may prove to be an effective, non-invasive method for monitoring blood sugar levels in diabetes, according to a University of California, Irvine study.
Sep 24, 2007 - 4:00:00 AM
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Latest Research
Both aerobic and resistance exercise improved blood sugar control in people with diabetes
In a new randomized controlled trial, both aerobic and resistance exercise improved glycemic/blood sugar control in people with type 2 diabetes. The greatest improvements came from combined aerobic and resistance training.
Sep 17, 2007 - 4:00:00 AM
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Latest Research
Immune police recognize good and bad guys in the body
Immune system police are as good at recognizing bad guys, such as bacteria and viruses, as they are our own tissue, researchers say.
Sep 14, 2007 - 4:00:00 AM
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Latest Research
Drug could improve pregnancy outcomes in wider range of women with insulin resistance
St. Louis, Sept. 6, 2007 — Women who are obese, have type 2 diabetes or a family history of type 2 diabetes could one day have more successful pregnancies because of a study at Washington University School of Medicine in St. Louis.
Sep 6, 2007 - 4:00:00 AM
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Latest Research
Sugary drinks, not fruit juice, may be linked to insulin
BOSTON (Sept. 5, 2007) — Steady increases in consumption of sugar-sweetened beverages over the last several decades, as well as rates of Type 2 diabetes mellitus, led nutritional epidemiologists at the Jean Mayer USDA Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University and colleagues to explore the relationship between sugar-sweetened beverage consumption and insulin resistance, a precursor to Type 2 diabetes. Their findings suggest that higher consumption of sugar-sweetened drinks, but not 100 percent fruit juice, may be associated with insulin resistance, even in otherwise healthy adults.
Sep 5, 2007 - 4:00:00 AM
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Latest Research
Environmental stress probed in cardiovascular disease, diabetes
How environmental stress contributes to cardiovascular disease and type II diabetes is under study at the Medical College of Georgia.
Sep 5, 2007 - 4:00:00 AM
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Latest Research
How insulin TORC2 blood sugar levels: glowing mice light the way
La Jolla, CA — With the help of genetically engineered mice whose livers turned into glowing light bulbs, researchers at the Salk Institute for Biological Studies have illuminated the underpinnings of an insidious and growing health concern— type II diabetes.
Sep 5, 2007 - 4:00:00 AM
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Latest Research
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Endocrinology
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Diabetes
Combination drug therapy for blood pressure may reduce cardiovascular outcomes for diabetes patients
By 2030, an estimated 350 million people will be living with diabetes worldwide. Individuals with type 2 diabetes are at an increased risk of cardiovascular outcomes including heart attack, stroke, and microvascular outcomes such as degenerative eye disease. Current guidelines recommend the lowering of blood pressure for people with type 2 diabetes to reduce the risk of such events, though a strategy to reduce blood pressure regardless of baseline blood pressure (ie, including people with diabetes who do not have raised blood pressure) has not been proven in randomised trials to date.
Sep 2, 2007 - 4:00:00 AM
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Latest Research
Treating diabetes during pregnancy can break link to childhood obesity
August 28, 2007 (Oakland, Calif) -- Treating diabetes during pregnancy can break the link between gestational diabetes and childhood obesity, according to a Kaiser Permanente study featured in the September issue of Diabetes Care.
Aug 28, 2007 - 4:00:00 AM
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Latest Research
Novel method enables genomic screening of blood vessels from patient tissue
COLUMBUS, Ohio – Scientists have developed a new method of capturing a complete genome-wide screening of blood vessel cells in their actual disease state, advancing the potential for genetic research on the tissue responsible for delivering nourishment that can accelerate the growth of both a cancer tumor or wound healing.
Aug 28, 2007 - 4:00:00 AM
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Latest Research
Focus on families aims to curb diabetes spread
Family lifestyles and their impact on the health of individual family members will be the focus of a new approach to preventing diabetes.
Aug 22, 2007 - 4:00:00 AM
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Latest Research
Diabetes appears to increase risk of death for patients with acute coronary syndromes
Individuals with diabetes and acute coronary syndromes (ACS) such as a heart attack or unstable angina have an increased risk of death at 30 days and one year after ACS, compared with ACS patients without diabetes, according to a study in the August 15 issue of JAMA.
Aug 14, 2007 - 4:00:00 AM
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Latest Research
UCLA researchers identify markers that may predict diabetes in still-healthy people
In the first large scale, multiethnic study of its kind, researchers at UCLA have confirmed the role played by three particular molecules known as cytokines as a cause of Type 2 diabetes, and further, have identified these molecules as early biological markers that may be used to more accurately predict future incidences of diabetes among apparently healthy individuals.
Aug 14, 2007 - 4:00:00 AM
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Latest Research
Adverse housing conditions contribute to diabetes risk
INDIANAPOLIS – Fair or poor housing conditions are associated with the risk of developing diabetes in urban, middle-aged African-Americans according to a study published in the Aug. 15 issue of the American Journal of Epidemiology by a team of investigators from Indiana University School of Medicine, the Regenstrief Institute, Washington University in St. Louis and other institutions.
Aug 13, 2007 - 4:00:00 AM
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Latest Research
RAND finds cases of undiagnosed diabetes drop sharply
The number of men in the United States with undiagnosed diabetes has declined sharply over the past 25 years, with Hispanics and African-Americans no longer more likely than whites to unknowingly have the disease, according to a RAND Corporation study issued today.
Aug 13, 2007 - 4:00:00 AM
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Latest Research
Adverse housing conditions contribute to diabetes risk
Studying people in their homes and neighborhoods, investigators have found that poor housing conditions contribute to the risk for diabetes in urban, middle-aged African-Americans.
Aug 13, 2007 - 4:00:00 AM
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Latest Research
Researchers find vitamin B1 deficiency key to vascular problems for diabetic patients
Researchers at Warwick Medical School, University of Warwick, have discovered that deficiency of thiamine – Vitamin B1 - may be key to a range of vascular problems for people with diabetes. They have also solved the mystery as to why thiamine deficiency in diabetes had remained hidden until now.
Aug 7, 2007 - 4:00:00 AM
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Latest Research
Reducing inflammation plays key role in type 1 diabetes therapy
BOSTON -- Researchers at Beth Israel Deaconess Medical Center (BIDMC) have found that a triple combination therapy consisting of both tolerance-inducing and anti-inflammatory properties is successful in abolishing adverse autoimmunity against insulin-producing cells in a mouse model of Type 1 diabetes.
Jul 31, 2007 - 4:00:00 AM
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Latest Research
New technique to 'see' and protect transplants successful in diabetic animal model
Researchers at Johns Hopkins have found a way to overcome a major stumbling block to developing successful insulin-cell transplants for people with type I diabetes.
Jul 29, 2007 - 4:00:00 AM
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Latest Research
Genetic finding sheds light on diseases causing blood vessel breakdown
Twenty-one years after they first described a fatal genetic disorder in Missouri and Arkansas families, scientists at Washington University School of Medicine in St. Louis have linked the condition to mutations in a gene known as TREX1.
Jul 29, 2007 - 4:00:00 AM
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Latest Research
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Endocrinology
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Diabetes
Some diabetes drugs may increase heart attack risk
London, July 28 - Two drugs commonly prescribed to treat Type 2 diabetes double the risk of heart failure, say scientists.
Jul 28, 2007 - 12:21:23 PM
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Latest Research
Older is better -- Top-10 comparison of diabetes drugs give metformin top grade
A type 2 diabetes drug taken orally and in widespread use for more than a decade has been found to have distinct advantages over nine other, mostly newer medications used to control the chronic disease, according to a study by researchers at Johns Hopkins.
Jul 24, 2007 - 4:00:00 AM
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Latest Research
Reducing insulin signaling in the brain can prolong lifespan
One route to a long and healthy life may be establishing the right balance in insulin signaling between the brain and the rest of the body, according to new research from ChildrenÂ’s Hospital Boston. The study, published in the July 20 issue of Science, not only reinforces the value of exercising and eating in moderation, but also helps explain a paradox in longevity research.
Jul 19, 2007 - 4:00:00 AM
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Latest Research
New review adds more reasons to avoid diabetes drug Avandia
Little evidence supports using rosiglitazone (Avandia) to improve the quality or length of life among adults with diabetes, according to a systematic review of data by German researchers.
Jul 17, 2007 - 4:00:00 AM
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Latest Research
Gene discovered for type 1 diabetes in children
Pediatrics researchers at The ChildrenÂ’s Hospital of Philadelphia and McGill University in Montreal have identified a gene variant that raises a childÂ’s risk for type 1 diabetes, formerly called juvenile diabetes. As investigators continue to pinpoint genes contributing to diabetes, they have their eyes on providing a scientific basis for designing better treatments and preventive measures for the disease.
Jul 15, 2007 - 4:00:00 AM
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Latest Research
Selenium supplements may increase the risk of type 2 diabetes
BUFFALO, N.Y. -- Selenium, an antioxidant included in multivitamin tablets thought to have a possible protective effect against the development of type 2 diabetes, may actually increase the risk of developing the disease, an analysis by researchers at the University at Buffalo has shown.
Jul 13, 2007 - 4:00:00 AM
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