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Last Updated: Nov 2, 2013 - 11:52:55 AM |
Latest Research
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Cancer
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Skin
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Melanoma
Compounds extracted from vegetables help to inhibit melanoma
Compounds extracted from green vegetables such as broccoli and cabbage could be a potent drug against melanoma, according to cancer researchers. Tests on mice suggest that these compounds, when combined with selenium, target tumors more safely and effectively than conventional therapy.
Mar 1, 2009 - 9:00:20 AM
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Latest Research
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Cancer
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Skin
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Melanoma
MicroRNA responsible for aggressiveness of metastatic melanoma cell lines
Scientists have long wondered how melanoma cells travel from primary tumors on the surface of the skin to the brain, liver and lungs, where they become more aggressive, resistant to therapy, and deadly. Now, scientists from NYU Langone Medical Center have identified the possible culprit—a short strand of RNA called microRNA (miRNA) that is over-expressed in metastatic melanoma cell lines and tissues.
Feb 9, 2009 - 12:10:26 PM
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Latest Research
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Cancer
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Skin
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Melanoma
A novel designer molecule to fight malignant melanoma
By playing it safe and using a two-pronged attack, a novel designer molecule fights malignant melanoma. It was created and tested by an international team of researchers led by the University of Bonn. In Nature Medicine's November issue they report about this promising strategy.
Nov 2, 2008 - 4:05:23 PM
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Latest Research
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Cancer
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Skin
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Melanoma
Listening to the sound of skin cancer
Researchers at the University of Missouri-Columbia can now detect the spread of skin cancer cells through the blood by literally listening to their sound. The unprecedented, minimally invasive technique causes melanoma cells to emit noise, and could let oncologists spot early signs of metastases -- as few as 10 cancer cells in a blood sample -- before they even settle in other organs.
Oct 17, 2006 - 2:06:00 AM
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Latest Research
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Cancer
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Skin
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Melanoma
Malignant melanoma cells secrete a potent embryonic growth factor
A Northwestern University research group has discovered that aggressive melanoma cells secrete Nodal, a protein that is critical to proper embryo formation. The researchers identified the potent and highly unstable embryonic growth factor by injecting aggressive melanoma cells into developing zebrafish embryos, which were used as "biosensors" for tumor cell-derived signals, and were consequently able to induce ectopic (abnormal) embryonic skull and backbone (axes) formation.
Jul 31, 2006 - 11:33:00 AM
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Latest Research
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Cancer
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Skin
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Melanoma
New mouse model technology in Melanoma vaccine tool-box
Cancer vaccines are being investigated in early-phase clinical trials around the world, with many of those trials recruiting patients with melanoma. Although tumor regressions have been seen in 10% to 20% of patients with metastatic melanoma, the great promise of cancer vaccines - controlling tumor growth and cancer spread without serious side-effects - remains as yet unrealized. This could be set to change with the publication of a new mouse model technology in Cancer Research, the journal of the American Association of Cancer Research, from a multi-national team led by investigators at the Brussels Branch of the international Ludwig Institute for Cancer Research (LICR).
Mar 28, 2006 - 7:44:00 PM
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Latest Research
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Cancer
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Skin
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Melanoma
Malignant melanoma cells reprogrammed !
Scientists at Northwestern University and the Stowers Institute for Medical Research have reprogrammed malignant melanoma cells to become normal melanocytes, or pigment cells, a development that may hold promise in treating of one of the deadliest forms of cancer.
Feb 28, 2006 - 5:45:00 PM
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Latest Research
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Cancer
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Skin
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Melanoma
New option for patients with metastatic melanoma
Patients with metastatic melanoma (MM) have new hope, says a recently published study by Mayo Clinic Cancer Center. The study, which shows the combination of paclitaxel and carboplatin (PC) appears to be effective for MM when traditional treatments have failed, is in this month's issue of Cancer
Jan 4, 2006 - 5:47:00 AM
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Latest Research
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Cancer
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Skin
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Melanoma
Positive family history increases risk of multiple primary melanomas
Patients with a family history of multiple melanoma skin cancer are at increased risk of multiple primary melanomas, according to a study in the October 5 issue of JAMA.
Oct 6, 2005 - 8:47:00 PM
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Latest Research
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Cancer
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Skin
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Melanoma
Role of Slug Gene in Melanoma Metastasis Identified
About 60,000 Americans will be diagnosed with melanoma this year, says the American Cancer Society, and 10,000 of those cases will be fatal. If not caught in the early stages, melanoma can be a particularly virulent form of cancer, spreading through the body with an efficiency that few tumors possess. Now, researchers at Whitehead Institute for Biomedical Research have discovered one of the reasons why this particular skin tumor is so ruthless. Unlike other cancers, melanoma is born with its metastatic engines fully revved.
Sep 6, 2005 - 6:36:00 AM
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Latest Research
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Cancer
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Skin
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Melanoma
Incidence Of Nonmelanoma Skin Cancer On The Rise Among Young Adults
A new study from Minnesota finds the incidence of nonmelanoma skin cancer increasing among men and women under the age of 40, according to an article in the August 10 issue of JAMA.
Aug 10, 2005 - 10:49:00 PM
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Latest Research
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Cancer
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Skin
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Melanoma
Curcumin - Potent turmeric spice blocks growth of melanoma
Curcumin, the pungent yellow spice found in both turmeric and curry powders, blocks a key biological pathway needed for development of melanoma and other cancers, say researchers from The University of Texas M. D. Anderson Cancer Center.
Jul 12, 2005 - 1:13:00 PM
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Latest Research
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Cancer
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Skin
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Melanoma
MITF master regulator is the target of gene amplification in melanoma
Researchers have pinpointed specific gene and protein over-production in metastatic melanoma, pointing the way to a possible new drug target, according to a study published in Nature July 7.
Jul 10, 2005 - 3:56:00 PM
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Latest Research
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Cancer
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Skin
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Melanoma
Human Anti-CTLA-4 Antibody in Combination with a gp100 Melanoma Vaccine Shows Significant Benefit in Treating Metastatic Melanoma
Medarex, Inc. ( Nasdaq: MEDX ) and Bristol-Myers Squibb Company ( NYSE: BMY ) announced today that complete or partial responses in seven of 56 patients with metastatic melanoma showed durability ranging from four months to the longest still ongoing at over 34 months, with five of the seven responses ongoing for more than two years.
Apr 25, 2005 - 8:06:00 AM
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Latest Research
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Cancer
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Skin
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Melanoma
CR011: An Antibody-Drug Conjugate Shows Durable Effects in Animal Models of Melanoma
CuraGen Corporation (Nasdaq: CRGN - News) announced today that new preclinical data on CR011, one of the oncology products being developed by the Company, were presented at the 96th Annual Meeting of the American Association for Cancer Research in Anaheim, CA. Preclinical data on CR011, an antibody-drug conjugate (ADC) that is expected to enter clinical trials in the first half of 2006, demonstrated that it caused tumor regression in animal xenograft models of melanoma.
Apr 18, 2005 - 9:10:00 AM
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Latest Research
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Cancer
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Skin
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Melanoma
New therapy for Advanced Melanoma
Melanoma is a particularly deadly form of skin cancer very resistant to treatment. Researchers at H. Lee Moffitt Cancer Center & Research Institute and the University of South Florida are testing a promising new therapy that prompts the immune system to aid in the fight against melanoma tumors.
Apr 6, 2005 - 6:57:00 PM
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Latest Research
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Cancer
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Skin
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Melanoma
Inhibiting Mutant v599EB-Raf protein could Prevent the Spread of Melanoma
Researchers at Penn State College of Medicine have identified the mechanism by which the most mutated gene in melanoma, called v599EB-Raf, aids melanoma tumor development demonstrating its importance as a therapeutic target.
Mar 23, 2005 - 7:36:00 PM
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Latest Research
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Cancer
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Skin
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Melanoma
Clinical Trials Tests CpG7909 and Melan-A Combination Melanoma Cancer Vaccines
Results from the first Phase 1 clinical trial of a vaccine composed of a synthetic bacterial sequence, CpG7909 (ProMune TM , Coley Pharmaceuticals), and a melanoma antigen, Melan-A, indicate that this vaccine combination is not only safe but also can improve and bolster immune responses to tumors.
Mar 18, 2005 - 4:38:00 PM
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