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Latest Research : Neurosciences : Brain Diseases
  Last Updated: Nov 2, 2013 - 11:52:55 AM

Latest Research : Neurosciences : Brain Diseases
Deep brain stimulation is effective at improving motor symptoms patients with advanced Parkinson's disease
A study published in the online version of The Lancet Neurology journal indicates that deep brain stimulation — also known as DBS — is effective at improving motor symptoms and quality of life in patients with advanced Parkinson's disease.
Jan 12, 2012 - 1:54:41 AM

Latest Research : Neurosciences : Brain Diseases : Epilepsy
High frequency oscillation analysis on EEGs offers a new surgical approach to improve seizure control
According to a study now available in Epilepsia, a journal of the International League Against Epilepsy (ILAE), the resection of brain regions containing high-frequency oscillations recorded on an electroencephalography (EEG), along with the visually-identified seizure-onset zone, may achieve a good seizure outcome in pediatric epilepsy.

Jul 30, 2011 - 7:27:47 PM

Latest Research : Neurosciences : Brain Diseases
Zileuton may help in treatment of Alzheimer's disease
The drug Zileuton used to treat asthma has been shown to help reduce the formation of amyloid beta, a peptide in the brain that is implicated in the development of Alzheimer's disease, according to researchers at Temple University's School of Medicine.

Mar 25, 2011 - 8:04:49 AM

Latest Research : Neurosciences : Brain Diseases : Epilepsy
Anti-epileptic drugs increase risk of fractures in patients above the age of fifty years
Most anti-epileptic drugs are associated with an increased risk of non-traumatic fracture in individuals 50 years of age and older, according to a report in the January issue of Archives of Neurology, one of the JAMA/Archives journals.

Jan 10, 2011 - 9:18:44 PM

Latest Research : Neurosciences : Brain Diseases : Epilepsy
More research and attention needed for epilepsy
Epilepsy, a common and serious neurologic disorder that affects millions of people, is not getting the public attention and funding for research it deserves, according to an editorial on a study published in the January 4, 2011, print issue of Neurology®, the medical journal of the American Academy of Neurology.

Dec 28, 2010 - 9:38:39 AM

Latest Research : Neurosciences : Brain Diseases : Epilepsy
Recent - onset seizures affect white matter development
A newly published study reported that children with new/recent onset epilepsy have significantly slowed expansion of white matter volume compared to healthy children over a two year interval.
May 19, 2010 - 2:19:59 PM

Latest Research : Neurosciences : Brain Diseases : Epilepsy
Ethosuximide - most effective treatment for childhood absence epilepsy
One of the oldest available anti-seizure medications, ethosuximide, is the most effective treatment for childhood absence epilepsy, according to initial outcomes published in this week's New England Journal of Medicine.

Mar 14, 2010 - 2:08:39 AM

Latest Research : Neurosciences : Brain Diseases : Epilepsy
Studies focusing on early diagnosis and treatment of epilepsy with minimal side-effects
Early diagnosis and treatment that quickly achieves seizure freedom with nominal side effects is the key goal to epilepsy management. Three studies highlighted at the AES annual meeting address this goal from different vantage points
Dec 7, 2008 - 2:20:28 PM

Latest Research : Neurosciences : Brain Diseases : Epilepsy
Sudden Unexpected Death In Epilepsy
A new study by researchers at UC Davis Medical Center suggests that the sudden unexplained deaths of some epilepsy patients may be a result of their brains not telling their bodies to breathe during seizures.


Nov 17, 2008 - 12:11:21 PM

Latest Research : Neurosciences : Brain Diseases : Epilepsy
Topiramate may increase the risk of birth defects
Taking the epilepsy drug topiramate alone or along with other epilepsy drugs during pregnancy may increase the risk of birth defects, according to a study published in the July 22, 2008, issue of Neurology®, the medical journal of the American Academy of Neurology.
Jul 22, 2008 - 10:41:23 AM

Latest Research : Neurosciences : Brain Diseases : Epilepsy
Glutamate- involved in blocking response to anti-epileptic medication
Using a rodent model of epilepsy, researchers found one of the body’s own neurotransmitters released during seizures, glutamate, turns on a signaling pathway in the brain that increases production of a protein that could reduce medication entry into the brain. Researchers say this may explain why approximately 30 percent of patients with epilepsy do not respond to antiepileptic medications. The study, conducted by researchers at the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health, and the University of Minnesota College of Pharmacy and Medical School, in collaboration with Heidrun Potschka’s laboratory at Ludwig-Maximilians-University in Munich, Germany, is available online and will appear in the May 2008, issue of Molecular Pharmacology.
Apr 14, 2008 - 1:41:38 PM

Latest Research : Aging : Dementia : Alzheimer's
New therapeutic targets for neurodegenerative diseases
The focus of work in the Neurosciences Department’s Neurobiology Laboratory at the University of the Basque Country’s Faculty of Medicine and Odontology is the investigation of the molecular and cellular bases of neurodegenerative illnesses – those that affect the brain and the spinal cord. Some of these neurodegenerative illnesses are well known and affect a significant part of the population, such as Alzheimer’s disease and multiple sclerosis.
May 10, 2007 - 8:22:23 AM

Latest Research : Neurosciences : Brain Diseases : Epilepsy
Responsive Neurostimulator System: An implantable device to treat epilepsy
About 2.5 million Americans of all ages have epilepsy. Think of it as a tiny electrical storm in the brain. Many people suffer from seizures affecting their quality of life or have side effects from epilepsy medications. However, patients with some types of the disease don't respond to surgery or may be at high risk for complications. That's why new devices surgically implanted in the brain itself offer hope for an effective epilepsy treatment.
Sep 14, 2006 - 4:54:00 PM

Latest Research : Neurosciences : Brain Diseases : Epilepsy
Defibrillator to prevent epileptic seizures?
Researchers at MIT are developing a device that could detect and prevent epileptic seizures before they become debilitating.
Sep 13, 2006 - 8:10:00 PM

Latest Research : Neurosciences : Brain Diseases : Epilepsy
Septum sets the tempo of brain's electrical activity
The brain's septum helps prevent epileptic seizures by inducing rhythmical electrical activity in the circuits of another area of the brain known as the hippocampus, according to a new study in the Journal of Neurophysiology. The researchers found that, by imposing a normal "theta" rhythm on chronically epileptic rats, they could reduce epileptic seizures by 86-97 percent.
Jun 20, 2006 - 7:06:00 PM

Latest Research : Neurosciences : Brain Diseases
Computerized atlas highlights brain structure changes in Williams syndrome
A computerized atlas has brought unprecedented sensitivity to the search for brain structure changes in a genetic condition known as Williams syndrome, revealing 33 abnormalities in the folding of the brain's surface. The disorder, which occurs in 1 in every 20,000 births, impairs visual and spatial skills but preserves musical ability and sociability.
May 22, 2006 - 3:22:00 AM

Latest Research : Neurosciences : Brain Diseases : Epilepsy
Multiple-stage surgery brings hope for Tuberous Sclerosis with intractable seizures
Sadly, none of the treatments for epilepsy—anti-seizure medications, a procedure called vagus nerve stimulation, a special diet —could quell the electrical storms in the young boy’s brain. Caused by a rare genetic disease called tuberous sclerosis, the seizures began when he was only 2 months old. By the time he was 5, he was having more than 10 a day. The seizures left him with the developmental capabilities of a 1-year-old child.

May 6, 2006 - 6:50:00 PM

Latest Research : Neurosciences : Brain Diseases
Brain Gene Expression Map (BGEM) - Powerful new tool for studying brain development
Scientists at St. Jude Children's Research Hospital have given investigators around the world free access to a powerful tool for studying brain development. The Internet-based tool, called the mouse Brain Gene Expression Map (BGEM), is one of the largest gene expression maps of an organ ever developed, according to the St. Jude researchers. They say the map will likely help scientists discover the genetic origins of brain cancers, which could speed development of novel drugs to treat them.
Mar 28, 2006 - 9:23:00 PM

Latest Research : Neurosciences : Brain Diseases : Epilepsy
Flexible Drug Dosing in Epilepsy Reduces Side Effects
For the first time, researchers compared dosing regimens of an antiepileptic drug (AED) used for treatment of partial epilepsy in adults, in conjunction with other AEDs. They looked at dosing used in clinical everyday life (flexible dosing) and that used in classical clinical trials (fixed dose) and discovered that the flexible dosing method was superior. Researchers observed how patients responded to these two methods of dosing therapy over a 12-week period. According to the researchers, while clinical trials have traditionally used fixed doses throughout a treatment period, clinical practice allows for the gradual adjustment of medication dose to enhance patient tolerability and enable optimum effective dosing, based on individual patient response.
Dec 30, 2005 - 3:49:00 PM

Latest Research : Neurosciences : Brain Diseases : Epilepsy
Depression and anxiety improve after epilepsy surgery
Depression and anxiety are common problems for people whose epilepsy cannot be controlled by medication. A new study found that depression and anxiety improve significantly after epilepsy surgery.
Dec 13, 2005 - 9:45:00 PM

Latest Research : Neurosciences : Brain Diseases
New technology to help children with cerebral palsy
Biomedical engineers at New Jersey Institute of Technology (NJIT) will use new technology to help children with cerebral palsy improve their movements, reduce stiffness in their joints and live fuller and more independent lives. Small robots mounted on wheelchairs, interactive video games and a robotic arm that can be programmed to guide and aid human motion – these are just a few of the technologies the engineers will use to help these children improve their muscular control and movements.
Nov 21, 2005 - 8:17:00 PM

Latest Research : Neurosciences : Brain Diseases : Epilepsy
Ketogenic diet prevents seizures
Although the high-fat, calorie-restricted ketogenic diet (KD) has long been used to prevent childhood epileptic seizures that are unresponsive to drugs, physicians have not really understood exactly why the diet works. New studies by a research team at Emory University School of Medicine show that the diet alters genes involved in energy metabolism in the brain, which in turn helps stabilize the function of neurons exposed to the challenges of epileptic seizures. This knowledge could help scientists identify specific molecular or genetic targets and lead to more effective drug treatments for epilepsy and brain damage.
Nov 13, 2005 - 7:55:00 PM

Latest Research : Neurosciences : Brain Diseases
How thinking can harm brain cells
Scientists at the University of Rochester Medical Center have targeted a new culprit and method of attack on neurologic functions in diseases such as Alzheimer's and dementia associated with HIV.
Nov 3, 2005 - 9:59:00 PM

Latest Research : Neurosciences : Brain Diseases : Epilepsy
Blood Test Can Help Determine Type of Seizure
Using a blood test to measure the level of the hormone prolactin can help determine, in certain clinical settings, whether an epileptic seizure has occurred, according to a guideline developed by the American Academy of Neurology and published in the September 13, 2005 issue of Neurology. The guideline authors reviewed all of the scientific evidence available on use of the prolactin blood test to diagnose seizures and developed evidence-based recommendations.
Sep 14, 2005 - 1:54:00 AM

Latest Research : Neurosciences : Brain Diseases
New non-surgical method of identifying brain infections
Researchers at Westmead Millennium Institute have discovered a safe, non-surgical method of identifying brain infections such as brain abscess, and an accurate and rapid way of diagnosing meningitis.
Sep 9, 2005 - 6:02:00 PM

Latest Research : Neurosciences : Brain Diseases : Epilepsy
Propofol is effective in pediatric refractory status epilepticus
Propofol is a safe and effective drug to treat children with refractory status epilepticus, and it is recommended before thiopental, according to a study in the August 23, 2005 issue of Neurology, the scientific journal of the American Academy of Neurology. Propofol and thiopental are widely used intravenous anesthetics which are also known to help control seizures.
Sep 1, 2005 - 8:03:00 AM

Latest Research : Neurosciences : Brain Diseases : Epilepsy
Astrocytes appear to play a key role in development of epilepsy
Star-shaped brain cells that are often overlooked by doctors and scientists as mere support cells appear to play a key role in the development of epilepsy, researchers say in a study published on-line August 14 in Nature Medicine. It's one of the first times scientists have produced firm evidence implicating the cells, known as astrocytes, in a common human disease.
Aug 15, 2005 - 5:50:00 PM

Latest Research : Neurosciences : Brain Diseases : Epilepsy
Novel treatment targets for absence seizures - Study
New research suggests novel treatment targets for the most common form of childhood epilepsy – with the potential to have fewer side effects than traditional therapy. The findings from Wake Forest University School of Medicine are reported today in the July issue of the Journal of Neurophysiology.
Jul 4, 2005 - 1:52:00 PM

Latest Research : Neurosciences : Brain Diseases : Epilepsy
Noninvasive evaluation of epilepsy patients prior to surgery- Funtional MRI
Brain surgery is a treatment option for epileptic patients who fail to respond to medical therapy.Prior to surgery, the epileptic focus and its proximity to important funtional areas needs to be identified . This was done in the past by invasive tests likethe Wada test and electrical cortical mapping.Functional MRI, which uses radio waves and a strong magnetic field, is a non-invasive test capable of identifying the location of critical brain functions that could be affected by the location of the seizure focus.

Jun 28, 2005 - 11:35:00 PM

Latest Research : Neurosciences : Brain Diseases : Epilepsy
Epilepsy surgery shows good results even after 30 years
A new study shows that the prognosis is good for people who have epilepsy surgery, even 30 years after the surgery. The study is published in the June 14 issue of Neurology, the scientific journal of the American Academy of Neurology.
Jun 14, 2005 - 3:23:00 AM

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